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Matthew Clark, Ph.D. - Publications

Affiliations: 
1986-1991 Chemistry Cornell University, Ithaca, NY, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Johannes JW, Bates S, Beigie C, Belmonte MA, Breen J, Cao S, Centrella PA, Clark MA, Cuozzo JW, Dumelin CE, Ferguson AD, Habeshian S, Hargreaves D, Joubran C, Kazmirski S, et al. Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors". Acs Medicinal Chemistry Letters. 8: 1204. PMID 29152055 DOI: 10.1021/acsmedchemlett.7b00397  0.32
2017 Johannes JW, Bates S, Beigie C, Belmonte MA, Breen J, Cao S, Centrella PA, Clark MA, Cuozzo JW, Dumelin CE, Ferguson AD, Habeshian S, Hargreaves D, Joubran C, Kazmirski S, et al. Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors. Acs Medicinal Chemistry Letters. 8: 239-244. PMID 28197319 DOI: 10.1021/acsmedchemlett.6b00464  0.32
2016 Ding Y, Franklin GJ, DeLorey JL, Centrella PA, Mataruse S, Clark MA, Skinner SR, Belyanskaya SL. Design and Synthesis of Biaryl DNA-Encoded Libraries. Acs Combinatorial Science. PMID 27571034 DOI: 10.1021/acscombsci.6b00078  1
2016 Janowitz Koch I, Clark MM, Thompson MJ, Deere-Machemer KA, Wang J, Duarte L, Gnanadesikan GE, Mccoy EL, Rubbi L, Stahler DR, Pellegrini M, Ostrander EA, Wayne RK, Sinsheimer JS, vonHoldt BM. The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves Molecular Ecology. DOI: 10.1111/mec.13480  0.32
2016 Clark ML, Rudshteyn B, Ge A, Chabolla SA, MacHan CW, Psciuk BT, Song J, Canzi G, Lian T, Batista VS, Kubiak CP. Orientation of cyano-substituted bipyridine Re(I) fac-tricarbonyl electrocatalysts bound to conducting au surfaces Journal of Physical Chemistry C. 120: 1657-1665. DOI: 10.1021/acs.jpcc.5b10912  0.32
2016 Li Y, Wang J, Clark ML, Kubiak CP, Xiong W. Characterizing interstate vibrational coherent dynamics of surface adsorbed catalysts by fourth-order 3D SFG spectroscopy Chemical Physics Letters. 650: 1-6. DOI: 10.1016/j.cplett.2016.02.031  0.32
2015 Henault J, Riggs JM, Karnell JL, Liarski VM, Li J, Shirinian L, Xu L, Casey KA, Smith MA, Khatry DB, Izhak L, Clarke L, Herbst R, Ettinger R, Petri M, ... Clark MR, et al. Self-reactive IgE exacerbates interferon responses associated with autoimmunity. Nature Immunology. PMID 26692173 DOI: 10.1038/ni.3326  0.64
2015 Wang J, Clark ML, Li Y, Kaslan CL, Kubiak CP, Xiong W. Short-Range Catalyst-Surface Interactions Revealed by Heterodyne Two-Dimensional Sum Frequency Generation Spectroscopy. The Journal of Physical Chemistry Letters. 6: 4204-9. PMID 26538035 DOI: 10.1021/acs.jpclett.5b02158  0.32
2015 Ding Y, O'Keefe H, DeLorey JL, Israel DI, Messer JA, Chiu CH, Skinner SR, Matico RE, Murray-Thompson MF, Li F, Clark MA, Cuozzo JW, Arico-Muendel C, Morgan BA. Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT). Acs Medicinal Chemistry Letters. 6: 888-93. PMID 26288689 DOI: 10.1021/acsmedchemlett.5b00138  1
2015 Litovchick A, Dumelin CE, Habeshian S, Gikunju D, Guié MA, Centrella P, Zhang Y, Sigel EA, Cuozzo JW, Keefe AD, Clark MA. Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library. Scientific Reports. 5: 10916. PMID 26061191 DOI: 10.1038/srep10916  1
2015 Yang H, Medeiros PF, Raha K, Elkins P, Lind KE, Lehr R, Adams ND, Burgess JL, Schmidt SJ, Knight SD, Auger KR, Schaber MD, Franklin GJ, Ding Y, DeLorey JL, ... ... Clark MA, et al. Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT). Acs Medicinal Chemistry Letters. 6: 531-6. PMID 26005528 DOI: 10.1021/acsmedchemlett.5b00025  1
2015 Keefe AD, Clark MA, Hupp CD, Litovchick A, Zhang Y. Chemical ligation methods for the tagging of DNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 80-8. PMID 25756406 DOI: 10.1016/j.cbpa.2015.02.015  1
2015 Ding Y, Clark MA. Robust Suzuki-Miyaura cross-coupling on DNA-linked substrates. Acs Combinatorial Science. 17: 1-4. PMID 25459065 DOI: 10.1021/co5001037  1
2015 Deng H, Zhou J, Sundersingh FS, Summerfield J, Somers D, Messer JA, Satz AL, Ancellin N, Arico-Muendel CC, Bedard KL, Beljean A, Belyanskaya SL, Bingham R, Smith SE, Boursier E, ... ... Clark MA, et al. Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library Acs Medicinal Chemistry Letters. 6: 919-924. DOI: 10.1021/acsmedchemlett.5b00179  1
2014 Vollmer MV, Machan CW, Clark ML, Antholine WE, Agarwal J, Schaefer HF, Kubiak CP, Walensky JR. Synthesis, Spectroscopy, and Electrochemistry of (α-Diimine)M(CO)3Br, M = Mn, Re, Complexes: Ligands Isoelectronic to Bipyridyl Show Differences in CO2 Reduction. Organometallics. 34: 3-12. PMID 25892841 DOI: 10.1021/om500838z  0.32
2014 Litovchick A, Clark MA, Keefe AD. Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags. Artificial Dna, Pna & Xna. 5: e27896. PMID 25483841 DOI: 10.4161/adna.27896  1
2014 Encinas L, O'Keefe H, Neu M, Remuiñán MJ, Patel AM, Guardia A, Davie CP, Pérez-Macías N, Yang H, Convery MA, Messer JA, Pérez-Herrán E, Centrella PA, Alvarez-Gómez D, Clark MA, et al. Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA. Journal of Medicinal Chemistry. 57: 1276-88. PMID 24450589 DOI: 10.1021/jm401326j  1
2014 Mast N, Li Y, Linger M, Clark M, Wiseman J, Pikuleva IA. Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice. The Journal of Biological Chemistry. 289: 3529-38. PMID 24352658 DOI: 10.1074/jbc.M113.532846  0.32
2014 Götz AW, Clark MA, Walker RC. An extensible interface for QM/MM molecular dynamics simulations with AMBER. Journal of Computational Chemistry. 35: 95-108. PMID 24122798 DOI: 10.1002/jcc.23444  1
2012 Isborn CM, Götz AW, Clark MA, Walker RC, Martínez TJ. Electronic Absorption Spectra from MM and ab initio QM/MM Molecular Dynamics: Environmental Effects on the Absorption Spectrum of Photoactive Yellow Protein. Journal of Chemical Theory and Computation. 8: 5092-5106. PMID 23476156 DOI: 10.1021/ct3006826  1
2012 Deng H, O'Keefe H, Davie CP, Lind KE, Acharya RA, Franklin GJ, Larkin J, Matico R, Neeb M, Thompson MM, Lohr T, Gross JW, Centrella PA, O'Donovan GK, Bedard KL, ... ... Clark MA, et al. Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT). Journal of Medicinal Chemistry. 55: 7061-79. PMID 22891645 DOI: 10.1021/jm300449x  1
2012 Mast N, Linger M, Clark M, Wiseman J, Stout CD, Pikuleva IA. In silico and intuitive predictions of CYP46A1 inhibition by marketed drugs with subsequent enzyme crystallization in complex with fluvoxamine. Molecular Pharmacology. 82: 824-34. PMID 22859721 DOI: 10.1124/mol.112.080424  0.32
2012 Rausch SM, Gonzalez BD, Clark MM, Patten C, Felten S, Liu H, Li Y, Sloan J, Yang P. SNPs in PTGS2 and LTA predict pain and quality of life in long term lung cancer survivors. Lung Cancer (Amsterdam, Netherlands). 77: 217-23. PMID 22464751 DOI: 10.1016/j.lungcan.2012.02.017  0.32
2010 Clark MA. Selecting chemicals: the emerging utility of DNA-encoded libraries Current Opinion in Chemical Biology. 14: 396-403. PMID 20346729 DOI: 10.1016/j.cbpa.2010.02.017  1
2009 Clark MA, Acharya RA, Arico-Muendel CC, Belyanskaya SL, Benjamin DR, Carlson NR, Centrella PA, Chiu CH, Creaser SP, Cuozzo JW, Davie CP, Ding Y, Franklin GJ, Franzen KD, Gefter ML, et al. Design, synthesis and selection of DNA-encoded small-molecule libraries. Nature Chemical Biology. 5: 647-54. PMID 19648931 DOI: 10.1038/nchembio.211  1
2004 Clark MA, Hilderbrand SA, Lippard SJ. Synthesis of fluorescein derivatives containing metal-coordinating heterocycles Tetrahedron Letters. 45: 7129-7131. DOI: 10.1016/j.tetlet.2004.07.131  1
2003 Clark MA, Duffy K, Tibrewala J, Lippard SJ. Synthesis and metal-binding properties of chelating fluorescein derivatives. Organic Letters. 5: 2051-4. PMID 12790526 DOI: 10.1021/ol0344570  1
2002 Clark MA, Wang Q, Ganem B. Oxidation of bicyclic oxazolines: Applications to glycomimetics and novel saccharide derivatives Tetrahedron Letters. 43: 347-349.  1
2001 Clark MA, Schoenfeld RC, Ganem B. The photochemistry of pyrylium salts: new photohydrations and photoamidations of heterocycles leading to bicyclic oxazolines and functionalized cyclopentenes. Journal of the American Chemical Society. 123: 10425-6. PMID 11604009 DOI: 10.1021/ja0166040  0.64
2000 Clark MA, Goering BK, Li J, Ganem B. Stereoselective synthetic approaches to highly substituted cyclopentanes via electrophilic additions to mono-, di-, and trisubstituted cyclopentenes. The Journal of Organic Chemistry. 65: 4058-69. PMID 10866624 DOI: 10.1021/jo000101f  1
2000 Clark MA, Ganem B. What about BOB? A synthetically useful protecting group Tetrahedron Letters. 41: 9523-9526.  1
1988 Brown F, Clark M, Graves D, Hadley M, Hatcher J, McArthur R, Riley G, Semple J. Variation of muscarinic activities of oxotremorine analogues Drug Development Research. 14: 343-347.  1
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