Tobin J. Dickerson, Ph.D. - Publications

Affiliations: 
1999-2000 Chemistry Virginia Polytechnic and State University, United States 
 2005- Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Website:
http://www.scripps.edu/dickerson/

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Aarde SM, Creehan KM, Vandewater SA, Dickerson TJ, Taffe MA. In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats. Psychopharmacology. 232: 3045-55. PMID 25925780 DOI: 10.1007/s00213-015-3944-8  1
2015 Aarde SM, Huang PK, Dickerson TJ, Taffe MA. Binge-like acquisition of 3,4-methylenedioxypyrovalerone (MDPV) self-administration and wheel activity in rats. Psychopharmacology. 232: 1867-77. PMID 25424056 DOI: 10.1007/s00213-014-3819-4  1
2014 Bompiani KM, Dickerson TJ. High-throughput screening technologies for botulinum neurotoxins. Current Topics in Medicinal Chemistry. 14: 2062-80. PMID 25335886  1
2014 Dickerson TJ, Smith GR, Pelletier JC, Reitz AB. 8-Hydroxyquinoline and hydroxamic acid inhibitors of botulinum neurotoxin BoNT/A. Current Topics in Medicinal Chemistry. 14: 2094-102. PMID 25335884  1
2014 Dickerson TJ, Smith GR, Reitz AB. Inhibition of botulinum neurotoxin BoNT/A. Current Topics in Medicinal Chemistry. 14: 2043. PMID 25335883  1
2014 Sakamuri RM, Capek P, Dickerson TJ, Barry CE, Mukundan H, Swanson BI. Detection of stealthy small amphiphilic biomarkers. Journal of Microbiological Methods. 103: 112-7. PMID 24880131 DOI: 10.1016/j.mimet.2014.05.012  1
2014 Caglič D, Krutein MC, Bompiani KM, Barlow DJ, Benoni G, Pelletier JC, Reitz AB, Lairson LL, Houseknecht KL, Smith GR, Dickerson TJ. Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain. Journal of Medicinal Chemistry. 57: 669-76. PMID 24387280 DOI: 10.1021/jm4012164  1
2014 Rodríguez LP, Vilariño N, Louzao MC, Dickerson TJ, Nicolaou KC, Frederick MO, Botana LM. Microsphere-based immunoassay for the detection of azaspiracids. Analytical Biochemistry. 447: 58-63. PMID 24215909 DOI: 10.1016/j.ab.2013.10.035  1
2013 Cagli? D, Bompiani KM, Krutein MC, ?apek P, Dickerson TJ. A high-throughput-compatible FRET-based platform for identification and characterization of botulinum neurotoxin light chain modulators. Journal of Visualized Experiments : Jove. 50908. PMID 24430674 DOI: 10.3791/50908  1
2013 Aarde SM, Huang PK, Creehan KM, Dickerson TJ, Taffe MA. The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats. Neuropharmacology. 71: 130-40. PMID 23597511 DOI: 10.1016/j.neuropharm.2013.04.003  1
2013 Aarde SM, Angrish D, Barlow DJ, Wright MJ, Vandewater SA, Creehan KM, Houseknecht KL, Dickerson TJ, Taffe MA. Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addiction Biology. 18: 786-99. PMID 23363010 DOI: 10.1111/adb.12038  1
2013 Miller ML, Creehan KM, Angrish D, Barlow DJ, Houseknecht KL, Dickerson TJ, Taffe MA. Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone). Drug and Alcohol Dependence. 127: 248-53. PMID 22832282 DOI: 10.1016/j.drugalcdep.2012.07.003  1
2012 Wright MJ, Angrish D, Aarde SM, Barlow DJ, Buczynski MW, Creehan KM, Vandewater SA, Parsons LH, Houseknecht KL, Dickerson TJ, Taffe MA. Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats. Plos One. 7: e44652. PMID 22952999 DOI: 10.1371/journal.pone.0044652  1
2012 Wright MJ, Vandewater SA, Angrish D, Dickerson TJ, Taffe MA. Mephedrone (4-methylmethcathinone) and d-methamphetamine improve visuospatial associative memory, but not spatial working memory, in rhesus macaques. British Journal of Pharmacology. 167: 1342-52. PMID 22748013 DOI: 10.1111/j.1476-5381.2012.02091.x  1
2012 Huang PK, Aarde SM, Angrish D, Houseknecht KL, Dickerson TJ, Taffe MA. Contrasting effects of d-methamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxypyrovalerone, and 4-methylmethcathinone on wheel activity in rats. Drug and Alcohol Dependence. 126: 168-75. PMID 22664136 DOI: 10.1016/j.drugalcdep.2012.05.011  1
2012 Smith GR, Caglič D, Capek P, Zhang Y, Godbole S, Reitz AB, Dickerson TJ. Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: extending towards the β-exosite. Bioorganic & Medicinal Chemistry Letters. 22: 3754-7. PMID 22542019 DOI: 10.1016/j.bmcl.2012.04.019  1
2012 Cagli? D, Dickerson TJ. A coincidence detector triggers botulinum neurotoxin translocation. Future Microbiology. 7: 185-8. PMID 22324987 DOI: 10.2217/fmb.11.157  1
2011 Capek P, Zhang Y, Barlow DJ, Houseknecht KL, Smith GR, Dickerson TJ. Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design. Acs Chemical Neuroscience. 2: 288-293. PMID 21743830 DOI: 10.1021/cn200021q  1
2011 Denery JR, Nunes AA, Dickerson TJ. Characterization of differences between blood sample matrices in untargeted metabolomics. Analytical Chemistry. 83: 1040-7. PMID 21175165 DOI: 10.1021/ac102806p  1
2010 Capek P, Dickerson TJ. Sensing the deadliest toxin: technologies for botulinum neurotoxin detection. Toxins. 2: 24-53. PMID 22069545 DOI: 10.3390/toxins2020024  1
2010 Denery JR, Nunes AA, Hixon MS, Dickerson TJ, Janda KD. Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis. Plos Neglected Tropical Diseases. 4. PMID 20957145 DOI: 10.1371/journal.pntd.0000834  1
2010 Capek P, Kirkconnell KS, Dickerson TJ. A bacteriophage-based platform for rapid trace detection of proteases. Journal of the American Chemical Society. 132: 13126-8. PMID 20812737 DOI: 10.1021/ja104572f  1
2010 Moreno AY, Azar MR, Warren NA, Dickerson TJ, Koob GF, Janda KD. A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Molecular Pharmaceutics. 7: 431-41. PMID 20104903 DOI: 10.1021/mp900213u  1
2009 Frederick MO, De Lamo Marin S, Janda KD, Nicolaou KC, Dickerson TJ. Monoclonal antibodies with orthogonal azaspiracid epitopes. Chembiochem : a European Journal of Chemical Biology. 10: 1625-9. PMID 19492388 DOI: 10.1002/cbic.200900201  1
2009 Treweek JB, Dickerson TJ, Janda KD. Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology. Accounts of Chemical Research. 42: 659-69. PMID 19275211 DOI: 10.1021/ar800247d  1
2009 Fischer A, Nakai Y, Eubanks LM, Clancy CM, Tepp WH, Pellett S, Dickerson TJ, Johnson EA, Janda KD, Montal M. Bimodal modulation of the botulinum neurotoxin protein-conducting channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 1330-5. PMID 19164566 DOI: 10.1073/pnas.0812839106  1
2009 Rohrbach AS, Dickerson TJ. Predicting protein evolution in vitro by phage escape technology. Molecular Biosystems. 5: 128-33. PMID 19156257 DOI: 10.1039/b814768j  1
2009 Nakai Y, Tepp WH, Dickerson TJ, Johnson EA, Janda KD. Function-oriented synthesis applied to the anti-botulinum natural product toosendanin. Bioorganic & Medicinal Chemistry. 17: 1152-7. PMID 19131252 DOI: 10.1016/j.bmc.2008.12.042  1
2008 Treweek JB, Sun C, Mayorov AV, Qi L, Levy CL, Roberts AJ, Dickerson TJ, Janda KD. Prevention of drug-induced memory impairment by immunopharmacotherapy. Journal of Medicinal Chemistry. 51: 6866-75. PMID 18921991 DOI: 10.1021/jm800506v  1
2008 Willis B, Eubanks LM, Dickerson TJ, Janda KD. The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison. Angewandte Chemie (International Ed. in English). 47: 8360-79. PMID 18844202 DOI: 10.1002/anie.200705531  1
2008 Park J, Dickerson TJ, Janda KD. Major sperm protein as a diagnostic antigen for onchocerciasis. Bioorganic & Medicinal Chemistry. 16: 7206-9. PMID 18632276 DOI: 10.1016/j.bmc.2008.06.038  1
2008 Lowery CA, Dickerson TJ, Janda KD. Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chemical Society Reviews. 37: 1337-46. PMID 18568160 DOI: 10.1039/b702781h  1
2008 Willis B, Eubanks LM, Wood MR, Janda KD, Dickerson TJ, Lerner RA. Biologically templated organic polymers with nanoscale order. Proceedings of the National Academy of Sciences of the United States of America. 105: 1416-9. PMID 18216240 DOI: 10.1073/pnas.0711308105  1
2007 Brogan AP, Dickerson TJ, Janda KD. Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes. Chemical Communications (Cambridge, England). 4952-4. PMID 18361380 DOI: 10.1039/b713273e  1
2007 Eubanks LM, Dickerson TJ. Investigating novel therapeutic targets and molecular mechanisms to treat botulinum neurotoxin A intoxication. Future Microbiology. 2: 677-87. PMID 18041908 DOI: 10.2217/17460913.2.6.677  1
2007 Capková K, Yoneda Y, Dickerson TJ, Janda KD. Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 6463-6. PMID 17951059 DOI: 10.1016/j.bmcl.2007.09.103  1
2007 Yao Y, Dickerson TJ, Hixon MS, Dyson HJ. NMR detection of adventitious xylose binding to the quorum-sensing protein SdiA of Escherichia coli. Bioorganic & Medicinal Chemistry Letters. 17: 6202-5. PMID 17889538 DOI: 10.1016/j.bmcl.2007.09.029  1
2007 Dickerson TJ, McKenzie KM, Hoyt AS, Wood MR, Janda KD, Brenner SB, Lerner RA. Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12703-8. PMID 17646645 DOI: 10.1073/pnas.0705362104  1
2007 Treweek J, Wee S, Koob GF, Dickerson TJ, Janda KD. Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 11580-4. PMID 17592122 DOI: 10.1073/pnas.0701328104  1
2007 Ino A, Dickerson TJ, Janda KD. Positional linker effects in haptens for cocaine immunopharmacotherapy. Bioorganic & Medicinal Chemistry Letters. 17: 4280-3. PMID 17531484 DOI: 10.1016/j.bmcl.2007.05.032  1
2007 Brogan AP, Eubanks LM, Koob GF, Dickerson TJ, Janda KD. Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. Journal of the American Chemical Society. 129: 3698-702. PMID 17335216 DOI: 10.1021/ja070022m  1
2007 Eubanks LM, Dickerson TJ, Janda KD. Technological advancements for the detection of and protection against biological and chemical warfare agents. Chemical Society Reviews. 36: 458-70. PMID 17325785 DOI: 10.1039/b615227a  1
2007 Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD. An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. Proceedings of the National Academy of Sciences of the United States of America. 104: 2602-7. PMID 17293454 DOI: 10.1073/pnas.0611213104  1
2006 Dickerson TJ, Janda KD. The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication. Acs Chemical Biology. 1: 359-69. PMID 17163773 DOI: 10.1021/cb600179d  1
2006 Eubanks LM, Rogers CJ, Beuscher AE, Koob GF, Olson AJ, Dickerson TJ, Janda KD. A molecular link between the active component of marijuana and Alzheimer's disease pathology. Molecular Pharmaceutics. 3: 773-7. PMID 17140265 DOI: 10.1021/mp060066m  1
2006 Rogers CJ, Eubanks LM, Dickerson TJ, Janda KD. Unexpected acetylcholinesterase activity of cocaine esterases. Journal of the American Chemical Society. 128: 15364-5. PMID 17131989 DOI: 10.1021/ja066241+  1
2006 Brogan AP, Dickerson TJ, Janda KD. Enamine-based aldol organocatalysis in water: are they really "all wet"? Angewandte Chemie (International Ed. in English). 45: 8100-2. PMID 17001595 DOI: 10.1002/anie.200601392  1
2006 McAllister LA, Hixon MS, Kennedy JP, Dickerson TJ, Janda KD. Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin. Journal of the American Chemical Society. 128: 4176-7. PMID 16568962 DOI: 10.1021/ja057699z  1
2006 Boldt GE, Dickerson TJ, Janda KD. Emerging chemical and biological approaches for the preparation of discovery libraries. Drug Discovery Today. 11: 143-8. PMID 16533712 DOI: 10.1016/S1359-6446(05)03697-4  1
2006 Zhu X, Dickerson TJ, Rogers CJ, Kaufmann GF, Mee JM, McKenzie KM, Janda KD, Wilson IA. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993). 14: 205-16. PMID 16472740 DOI: 10.1016/j.str.2005.10.014  1
2006 Yao Y, Martinez-Yamout MA, Dickerson TJ, Brogan AP, Wright PE, Dyson HJ. Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones. Journal of Molecular Biology. 355: 262-73. PMID 16307757 DOI: 10.1016/j.jmb.2005.10.041  1
2006 Rogers CJ, Dickerson TJ, Janda KD. Kinetic isotope and thermodynamic analysis of the nornicotine-catalyzed aqueous aldol reaction Tetrahedron. 62: 352-356. DOI: 10.1016/j.tet.2005.09.094  1
2005 Dickerson TJ, Janda KD. Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. The Aaps Journal. 7: E579-86. PMID 16353936 DOI: 10.1208/aapsj070359  1
2005 Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate Chemistry. 16: 1352-5. PMID 16287229 DOI: 10.1021/bc050213j  1
2005 Dickerson TJ, Beuscher AE, Rogers CJ, Hixon MS, Yamamoto N, Xu Y, Olson AJ, Janda KD. Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library. Biochemistry. 44: 14845-53. PMID 16274232 DOI: 10.1021/bi051613x  1
2005 Eubanks LM, Dickerson TJ, Janda KD. Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A. Febs Letters. 579: 5361-4. PMID 16198354 DOI: 10.1016/j.febslet.2005.08.072  1
2005 Brogan AP, Dickerson TJ, Boldt GE, Janda KD. Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development. Proceedings of the National Academy of Sciences of the United States of America. 102: 10433-8. PMID 16014706 DOI: 10.1073/pnas.0504721102  1
2005 Rogers CJ, Mee JM, Kaufmann GF, Dickerson TJ, Janda KD. Toward cocaine esterase therapeutics. Journal of the American Chemical Society. 127: 10016-7. PMID 16011362 DOI: 10.1021/ja053086a  1
2005 Dickerson TJ, Kaufmann GF, Janda KD. Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy. Expert Opinion On Biological Therapy. 5: 773-81. PMID 15952908 DOI: 10.1517/14712598.5.6.773  1
2005 Rogers CJ, Dickerson TJ, Brogan AP, Janda KD. Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis. The Journal of Organic Chemistry. 70: 3705-8. PMID 15845010 DOI: 10.1021/jo050161r  1
2005 Reed NN, Dickerson TJ, Boldt GE, Janda KD. Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer. The Journal of Organic Chemistry. 70: 1728-31. PMID 15730294 DOI: 10.1021/jo048009x  1
2005 Kaufmann GF, Sartorio R, Lee SH, Rogers CJ, Meijler MM, Moss JA, Clapham B, Brogan AP, Dickerson TJ, Janda KD. Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones. Proceedings of the National Academy of Sciences of the United States of America. 102: 309-14. PMID 15623555 DOI: 10.1073/pnas.0408639102  1
2005 Rogers CJ, Dickerson TJ, Wentworth P, Janda KD. A high-swelling reagent scaffold suitable for use in aqueous and organic solvents Tetrahedron. 61: 12140-12144. DOI: 10.1016/j.tet.2005.07.115  1
2004 Dickerson TJ, Reed NN, LaClair JJ, Janda KD. A precipitator for the detection of thiophilic metals in aqua. Journal of the American Chemical Society. 126: 16582-6. PMID 15600364 DOI: 10.1021/ja045798r  1
2004 Dickerson TJ, Lovell T, Meijler MM, Noodleman L, Janda KD. Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis. The Journal of Organic Chemistry. 69: 6603-9. PMID 15387581 DOI: 10.1021/jo048894j  1
2004 Dickerson TJ, Yamamoto N, Ruiz DI, Janda KD. Immunological consequences of methamphetamine protein glycation. Journal of the American Chemical Society. 126: 11446-7. PMID 15366884 DOI: 10.1021/ja047690h  1
2004 Dickerson TJ, Yamamoto N, Janda KD. Antibody-catalyzed oxidative degradation of nicotine using riboflavin. Bioorganic & Medicinal Chemistry. 12: 4981-7. PMID 15336277 DOI: 10.1016/j.bmc.2004.07.006  1
2003 Dickerson TJ, Tremblay MR, Hoffman TZ, Ruiz DI, Janda KD. Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states. Journal of the American Chemical Society. 125: 15395-401. PMID 14664584 DOI: 10.1021/ja038016n  1
2003 Dickerson TJ, Janda KD. Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 8182-7. PMID 12815102 DOI: 10.1073/pnas.1332847100  1
2003 Gambs C, Dickerson TJ, Mahajan S, Pasternack LB, Janda KD. High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins. The Journal of Organic Chemistry. 68: 3673-8. PMID 12713377 DOI: 10.1021/jo034152z  1
2002 Dickerson TJ, Janda KD. A previously undescribed chemical link between smoking and metabolic disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 15084-8. PMID 12403823 DOI: 10.1073/pnas.222561699  1
2002 Dickerson TJ, Reed NN, Janda KD. Soluble polymers as scaffolds for recoverable catalysts and reagents. Chemical Reviews. 102: 3325-44. PMID 12371887 DOI: 10.1021/cr010335e  1
2002 Dickerson TJ, Janda KD. Aqueous aldol catalysis by a nicotine metabolite. Journal of the American Chemical Society. 124: 3220-1. PMID 11916401 DOI: 10.1021/ja017774f  1
2002 Moss JA, Dickerson TJ, Janda KD. Solid phase peptide synthesis on JandaJel™ resin Tetrahedron Letters. 43: 37-40. DOI: 10.1016/S0040-4039(01)02076-7  1
2001 Dickerson TJ, Reed NN, Janda KD. Regio-reactive resin: a platform for orthogonal loading using the polymer backbone and cross-linker. Bioorganic & Medicinal Chemistry Letters. 11: 1507-9. PMID 11412970 DOI: 10.1016/S0960-894X(01)00152-4  1
2001 Tremblay MR, Dickerson TJ, Janda KD. Advances in Antibody Catalysis of Cycloaddition Reactions Advanced Synthesis and Catalysis. 343: 577-585.  1
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