Richard H. Griffey - Publications

Affiliations: 
1984 University of Utah, Salt Lake City, UT 

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, et al. Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue. Journal of Medicinal Chemistry. 53: 3919-26. PMID 20420385 DOI: 10.1021/jm901489k  1
2010 Paulsen RB, Seth PP, Swayze EE, Griffey RH, Skalicky JJ, Cheatham TE, Davis DR. Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proceedings of the National Academy of Sciences of the United States of America. 107: 7263-8. PMID 20360559 DOI: 10.1073/pnas.0911896107  1
2007 Hanessian S, Adhikari S, Szychowski J, Pachamuthu K, Wang X, Migawa MT, Griffey RH, Swayze EE. Corrigendum to "Probing the ribosomal RNA A-site with functionally diverse analogues of paromomycin-synthesis of ring I mimetics". [Tetrahedron 63 (2007) 827-846] (DOI:10.1016/j.tet.2006.10.079) Tetrahedron. 63: 5329. DOI: 10.1016/j.tet.2007.03.161  1
2007 Hanessian S, Adhikari S, Szychowski J, Pachamuthu K, Wang X, Migawa MT, Griffey RH, Swayze EE. Probing the ribosomal RNA A-site with functionally diverse analogues of paromomycin-synthesis of ring I mimetics Tetrahedron. 63: 827-846. DOI: 10.1016/j.tet.2006.10.079  1
2006 Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids. Journal of Medicinal Chemistry. 49: 2534-42. PMID 16610796 DOI: 10.1021/jm051275y  1
2006 Rao Y, Venot A, Swayze EE, Griffey RH, Boons GJ. Trisaccharide mimetics of the aminoglycoside antibiotic neomycin. Organic & Biomolecular Chemistry. 4: 1328-37. PMID 16557321 DOI: 10.1039/b517725a  1
2006 Dande P, Prakash TP, Sioufi N, Gaus H, Jarres R, Berdeja A, Swayze EE, Griffey RH, Bhat B. Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications. Journal of Medicinal Chemistry. 49: 1624-34. PMID 16509579 DOI: 10.1021/jm050822c  1
2006 Swayze EE, Griffey RH, Bennett CF. Nucleic acids (deoxyribonucleic acid and ribonucleic acid) Comprehensive Medicinal Chemistry Ii. 2: 1037-1052.  1
2005 Seth PP, Miyaji A, Jefferson EA, Sannes-Lowery KA, Osgood SA, Propp SS, Ranken R, Massire C, Sampath R, Ecker DJ, Swayze EE, Griffey RH. SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain. Journal of Medicinal Chemistry. 48: 7099-102. PMID 16279767 DOI: 10.1021/jm050815o  1
2005 Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, et al. Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid. Journal of Medicinal Chemistry. 48: 6741-9. PMID 16220989 DOI: 10.1021/jm050490b  1
2005 Migawa MT, Risen LM, Griffey RH, Swayze EE. An efficient synthesis of gougerotin and related analogues using solid- and solution-phase methodology. Organic Letters. 7: 3429-32. PMID 16048309 DOI: 10.1021/ol0507322  1
2005 Prakash TP, Allerson CR, Dande P, Vickers TA, Sioufi N, Jarres R, Baker BF, Swayze EE, Griffey RH, Bhat B. Positional effect of chemical modifications on short interference RNA activity in mammalian cells. Journal of Medicinal Chemistry. 48: 4247-53. PMID 15974578 DOI: 10.1021/jm050044o  1
2005 Sampath R, Hofstadler SA, Blyn LB, Eshoo MW, Hall TA, Massire C, Levene HM, Hannis JC, Harrell PM, Neuman B, Buchmeier MJ, Jiang Y, Ranken R, Drader JJ, Samant V, ... Griffey RH, et al. Rapid identification of emerging pathogens: coronavirus. Emerging Infectious Diseases. 11: 373-9. PMID 15757550 DOI: 10.3201/eid1103.040629  1
2005 Allerson CR, Sioufi N, Jarres R, Prakash TP, Naik N, Berdeja A, Wanders L, Griffey RH, Swayze EE, Bhat B. Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA. Journal of Medicinal Chemistry. 48: 901-4. PMID 15715458 DOI: 10.1021/jm049167j  1
2004 François B, Szychowski J, Adhikari SS, Pachamuthu K, Swayze EE, Griffey RH, Migawa MT, Westhof E, Hanessian S. Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site. Angewandte Chemie (International Ed. in English). 43: 6735-8. PMID 15593140 DOI: 10.1002/anie.200462092  1
2004 Esau C, Kang X, Peralta E, Hanson E, Marcusson EG, Ravichandran LV, Sun Y, Koo S, Perera RJ, Jain R, Dean NM, Freier SM, Bennett CF, Lollo B, Griffey R. MicroRNA-143 regulates adipocyte differentiation Journal of Biological Chemistry. 279: 52361-52365. PMID 15504739 DOI: 10.1074/jbc.C400438200  1
2004 Venot A, Swayze EE, Griffey RH, Boons GJ. Disaccharide mimetics of the aminoglycoside antibiotic neamine. Chembiochem : a European Journal of Chemical Biology. 5: 1228-36. PMID 15368574 DOI: 10.1002/cbic.200400105  1
2004 He Y, Yang J, Wu B, Robinson D, Sprankle K, Kung PP, Lowery K, Mohan V, Hofstadler S, Swayze EE, Griffey R. Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry. Bioorganic & Medicinal Chemistry Letters. 14: 695-9. PMID 14741271 DOI: 10.1016/j.bmcl.2003.11.031  1
2003 Wu B, Yang J, Robinson D, Hofstadler S, Griffey R, Swayze EE, He Y. Synthesis of linked carbohydrates and evaluation of their binding for 16S RNA by mass spectrometry Bioorganic and Medicinal Chemistry Letters. 13: 3915-3918. PMID 14592474 DOI: 10.1016/j.bmcl.2003.09.005  1
2003 Cummins LL, Chen S, Blyn LB, Sannes-Lowery KA, Drader JJ, Griffey RH, Hofstadler SA. Multitarget affinity/specificity screening of natural products: finding and characterizing high-affinity ligands from complex mixtures by using high-performance mass spectrometry. Journal of Natural Products. 66: 1186-90. PMID 14510594 DOI: 10.1021/np0301137  1
2003 Ding Y, Hofstadler SA, Swayze EE, Risen L, Griffey RH. Design and synthesis of paromomycin-related heterocycle-substituted aminoglycoside mimetics based on a mass spectrometry RNA-binding assay. Angewandte Chemie (International Ed. in English). 42: 3409-12. PMID 12888972 DOI: 10.1002/anie.200351354  1
2003 Ding Y, Hofstadler SA, Swayze EE, Griffey RH. Efficient Synthesis of Heterocyclic 2-Deoxysteptamine Derivatives as RNA Binding Ligands Chemistry Letters. 32: 908-909. DOI: 10.1246/cl.2003.908  1
2003 Li J, Lee SA, Anderson A, Lettress L, Griffey RH, Mohan V. Temperature-dependent Raman and infrared spectra of nucleosides. III - Deoxycytidine Journal of Raman Spectroscopy. 34: 183-191. DOI: 10.1002/jrs.973  1
2003 Seeberger PH, Baumann M, Zhang G, Kanemitsu T, Swayze EE, Hofstadler SA, Griffey RH. Synthesis of neomycin analogs to investigate aminoglycoside-RNA interactions Synlett. 1323-1326.  1
2002 Fogel GB, Porto VW, Weekes DG, Fogel DB, Griffey RH, McNeil JA, Lesnik E, Ecker DJ, Sampath R. Discovery of RNA structural elements using evolutionary computation. Nucleic Acids Research. 30: 5310-7. PMID 12466557 DOI: 10.1093/nar/gkf653  1
2002 Griffey RH. Converting solution macromolecular thermodynamic properties into gas-phase mass spectrometry observations. Chemistry & Biology. 9: 958-9. PMID 12323369 DOI: 10.1016/S1074-5521(02)00221-1  1
2002 Swayze EE, Jefferson EA, Sannes-Lowery KA, Blyn LB, Risen LM, Arakawa S, Osgood SA, Hofstadler SA, Griffey RH. SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets. Journal of Medicinal Chemistry. 45: 3816-9. PMID 12190303 DOI: 10.1021/jm0255466  1
2002 Chen S, Lesnik EA, Hall TA, Sampath R, Griffey RH, Ecker DJ, Blyn LB. A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome. Bio Systems. 65: 157-77. PMID 12069726 DOI: 10.1016/S0303-2647(02)00013-8  1
2002 Li J, Lee SA, Pinnick DA, Anderson A, Smith W, Griffey RH, Mohan V. Raman and infrared studies of nucleosides at high pressures: II. Cytidine. Journal of Biomolecular Structure & Dynamics. 19: 1111-20. PMID 12023813 DOI: 10.1080/07391102.2002.10506814  1
2002 Griffey RH, Swayze EE. RNA-targeted therapeutics: Prospects and promise Expert Opinion On Therapeutic Patents. 12: 1367-1374. DOI: 10.1517/13543776.12.9.1367  1
2001 Hofstadler SA, Griffey RH. Analysis of noncovalent complexes of DNA and RNA by mass spectrometry. Chemical Reviews. 101: 377-90. PMID 11712252 DOI: 10.1021/cr990105o  1
2001 Major F, Griffey R. Computational methods for RNA structure determination Current Opinion in Structural Biology. 11: 282-286. PMID 11406375 DOI: 10.1016/S0959-440X(00)00203-7  1
2001 Ding Y, Hofstadler SA, Swayze EE, Griffey RH. An efficient synthesis of mimetics of neamine for RNA recognition. Organic Letters. 3: 1621-3. PMID 11405670 DOI: 10.1021/ol015794g  1
2001 Sannes-Lowery KA, Drader JJ, Griffey RH, Hofstadler SA. High performance mass spectrometry as a drug discovery tool: A high throughput screening assay to identify RNA-binding ligands Proceedings of Spie - the International Society For Optical Engineering. 4264: 27-36. DOI: 10.1117/12.424586  1
2001 Hofstadler SA, Sannes-Lowery KA, Griffey RH. m/z-Selective infrared multiphoton dissociation in a penning trap using sidekick trapping and an rf-tickle pulse Rapid Communications in Mass Spectrometry. 15: 945-951. DOI: 10.1002/rcm.312  1
2001 Lee SA, Li J, Anderson A, Smith W, Griffey RH, Mohan V. Temperature-dependent Raman and infrared spectra of nucleosides. II-cytidine Journal of Raman Spectroscopy. 32: 795-802. DOI: 10.1002/jrs.749  1
2000 Hofstadler SA, Griffey RH. Mass spectrometry as a drug discovery platform against RNA targets. Current Opinion in Drug Discovery & Development. 3: 423-31. PMID 19649873  1
2000 Chen YZ, Mohan V, Griffey RH. Spontaneous base flipping in DNA and its possible role in methyltransferase binding. Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 62: 1133-7. PMID 11088571 DOI: 10.1103/PhysRevE.62.1133  1
2000 Chen YZ, Mohan V, Griffey RH. Base opening in RNA and DNA duplexes: implication for RNA stability. Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 61: 5640-5. PMID 11031620  1
2000 Filikov AV, Mohan V, Vickers TA, Griffey RH, Cook PD, Abagyan RA, James TL. Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR. Journal of Computer-Aided Molecular Design. 14: 593-610. PMID 10921774 DOI: 10.1023/A:1008121029716  1
2000 Sannes-Lowery KA, Griffey RH, Hofstadler SA. Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry. Analytical Biochemistry. 280: 264-71. PMID 10790309 DOI: 10.1006/abio.2000.4550  1
2000 Blyn LB, Risen LM, Griffey RH, Draper DE. The RNA-binding domain of ribosomal protein L11 recognizes an rRNA tertiary structure stabilized by both thiostrepton and magnesium ion. Nucleic Acids Research. 28: 1778-84. PMID 10734197  1
2000 Hofstadler SA, Sannes-Lowery KA, Griffey RH. Enhanced gas-phase hydrogen-deuterium exchange of oligonucleotide and protein ions stored in an external multipole ion reservoir. Journal of Mass Spectrometry : Jms. 35: 62-70. PMID 10633235 DOI: 10.1002/(SICI)1096-9888(200001)35:1<62::AID-JMS913>3.0.CO;2-9  1
2000 Griffey RH, Sannes-Lowery KA, Drader JJ, Mohan V, Swayze EE, Hofstadler SA. Characterization of low-affinity complexes between RNA and small molecules using electrospray ionization mass spectrometry Journal of the American Chemical Society. 122: 9933-9938. DOI: 10.1021/ja0017108  1
2000 Sannes-Lowery KA, Drader JJ, Griffey RH, Hofstadler SA. Fourier transform ion cyclotron resonance mass spectrometry as a high throughput affinity screen to identify RNA binding ligands Trac - Trends in Analytical Chemistry. 19: 481-491. DOI: 10.1016/S0165-9936(00)00029-7  1
2000 Lee SA, Anderson A, Smith W, Griffey RH, Mohan V. Temperature-dependent Raman and infrared spectra of nucleosides. Part I - Adenosine Journal of Raman Spectroscopy. 31: 891-896. DOI: 10.1002/1097-4555(200010)31:10<891::AID-JRS606>3.0.CO;2-2  1
2000 Ding Y, Swayze EE, Hofstadler SA, Griffey RH. Efficient synthesis of neomycin B related aminoglycosides Tetrahedron Letters. 41: 4049-4052.  1
1999 Hofstadler SA, Sannes-Lowery KA, Griffey RH. A gated-beam electrospray ionization source with an external ion reservoir. A new tool for the characterization of biomolecules using electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 13: 1971-9. PMID 10510407 DOI: 10.1002/(SICI)1097-0231(19991030)13:20<1971::AID-RCM740>3.0.CO;2-D  1
1999 Griffey RH, Hofstadler SA, Sannes-Lowery KA, Ecker DJ, Crooke ST. Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 96: 10129-33. PMID 10468574 DOI: 10.1073/pnas.96.18.10129  1
1999 Hofstadler SA, Sannes-Lowery KA, Crooke ST, Ecker DJ, Sasmor H, Manalili S, Griffey RH. Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: a paradigm for high-throughput affinity screening. Analytical Chemistry. 71: 3436-40. PMID 10464476 DOI: 10.1021/ac990262n  1
1999 Ecker DJ, Griffey RH. RNA as a small-molecule drug target: doubling the value of genomics. Drug Discovery Today. 4: 420-429. PMID 10461152 DOI: 10.1016/S1359-6446(99)01389-6  1
1999 Martin KC, Pinnick DA, Lee SA, Anderson A, Smith W, Griffey RH, Mohan V. Raman and infrared studies of nucleosides at high pressures: I. Adenosine. Journal of Biomolecular Structure & Dynamics. 16: 1159-67. PMID 10447200 DOI: 10.1080/07391102.1999.10508324  1
1999 Griffey RH, Greig MJ, An H, Sasmor H, Manalili S. Targeted site-specific gas-phase cleavage of oligoribonucleotides. Application in mass spectrometry-based identification of ligand binding sites Journal of the American Chemical Society. 121: 474-475. DOI: 10.1021/ja983131x  1
1999 Griffey RH, Greig MJ, Robinson JM, Laude DA. Gas-phase hydrogen-deuterium exchange in phosphorothioate d(GTCAG) and d(TCGAT) Rapid Communications in Mass Spectrometry. 13: 113-117. DOI: 10.1002/(SICI)1097-0231(19990130)13:2<113::AID-RCM464>3.0.CO;2-X  1
1999 Kawasaki AM, Casper MD, Gaus HJ, Herrmann R, Griffey RH, Cook PD. Solution phase combinatorial chemistry. Purine- and pyrimidine-based libraries with antibacterial activity via solution phase simultaneous addition of functionalities Nucleosides and Nucleotides. 18: 659-660.  1
1998 Sannes-Lowery K, Griffey RH, Kruppa GH, Speir JP, Hofstadler SA. Multipole storage assisted dissociation, a novel in-source dissociation technique for electrospray ionization generated ions. Rapid Communications in Mass Spectrometry : Rcm. 12: 1957-61. PMID 9842743 DOI: 10.1002/(SICI)1097-0231(19981215)12:23<1957::AID-RCM418>3.0.CO;2-M  1
1998 Robinson JM, Greig MJ, Griffey RH, Mohan V, Laude DA. Hydrogen/deuterium exchange of nucleotides in the gas phase. Analytical Chemistry. 70: 3566-71. PMID 9737208  1
1998 Chen YZ, Mohan V, Griffey RH. The opening of a single base without perturbations of neighboring nucleotides: a study on crystal B-DNA duplex d(CGCGAATTCGCG)2. Journal of Biomolecular Structure & Dynamics. 15: 765-77. PMID 9514252 DOI: 10.1080/07391102.1998.10508991  1
1998 Griffey RH, An H, Cummins LL, Gaus HJ, Haly B, Herrmann R, Dan Cook P. Rapid deconvolution of combinatorial libraries using HPLC fractionation Tetrahedron. 54: 4067-4076. DOI: 10.1016/S0040-4020(98)00135-5  1
1998 An H, Wang T, Mohan V, Griffey RH, Dan Cook P. Solution phase combinatorial chemistry. Discovery of 13- and 15-membered polyazapyridinocyclophane libraries with antibacterial activity Tetrahedron. 54: 3999-4012. DOI: 10.1016/S0040-4020(98)00131-8  1
1998 Hofstadler SA, Griffey RH, Pasa-Tolic L, Smith RD. The use of a stable internal mass standard for accurate mass measurements of oligonucleotide fragment ions using electrospray ionization fourier transform ion cyclotron resonance mass spectrometry with infrared multiphoton dissociation Rapid Communications in Mass Spectrometry. 12: 1400-1404. DOI: 10.1002/(SICI)1097-0231(19981015)12:19<1400::AID-RCM337>3.0.CO;2-T  1
1998 Chen YZ, Mohan V, Griffey RH. Principal torsion angles of collective motions in biomolecules: A study of a single base opening in DNA duplexes Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 58: 909-913.  1
1998 Lind KE, Sherlin LD, Mohan V, Griffey RH, Ferguson DM. Parameterization and Simulation of the Physical Properties of Phosphorothioate Nucleic Acids Acs Symposium Series. 682: 41-54.  1
1998 Chen YZ, Mohan V, Griffey RH. Effect of backbone ζ torsion angle on low energy single base opening in B-DNA crystal structures Chemical Physics Letters. 287: 570-574.  1
1997 Dean NM, Griffey RH. Identification and characterization of second-generation antisense oligonucleotides. Antisense & Nucleic Acid Drug Development. 7: 229-33. PMID 9212916  1
1997 Steinke CA, Reeves KK, Powell JW, Lee SA, Chen YZ, Wyrzykiewicz T, Griffey RH, Mohan V. Vibrational analysis of phosphorothioate DNA: II. The POS group in the model compound dimethyl phosphorothioate [(CH3O)2(POS)]-. Journal of Biomolecular Structure & Dynamics. 14: 509-16. PMID 9172650 DOI: 10.1080/07391102.1997.10508149  1
1997 Griffey RH, Greig MJ, Gaus HJ, Liu K, Monteith D, Winniman M, Cummins LL. Characterization of oligonucleotide metabolism in vivo via liquid chromatography/electrospray tandem mass spectrometry with a quadrupole ion trap mass spectrometer. Journal of Mass Spectrometry : Jms. 32: 305-13. PMID 9075339 DOI: 10.1002/(SICI)1096-9888(199703)32:3<305::AID-JMS482>3.0.CO;2-R  1
1997 Griffey RH, Greig MJ. Detection of base pair mismatches in duplex DNA and RNA oligonucleotides using electrospray mass spectrometry Proceedings of Spie - the International Society For Optical Engineering. 2985: 82-86. DOI: 10.1117/12.274340  1
1997 An H, Cummins LL, Griffey RH, Bharadwaj R, Haly BD, Fraser AS, Wilson-Lingardo L, Risen LM, Wyatt JR, Cook PD. Solution phase combinatorial chemistry. Discovery of novel polyazapyridinophanes with potent antibacterial activity by a solution phase simultaneous addition of functionalities approach Journal of the American Chemical Society. 119: 3696-3708. DOI: 10.1021/ja964153r  1
1997 Griffey RH, Sasmor H, Greig MJ. Oligonucleotide charge states in negative ionization electrospray-mass spectrometry are a function of solution ammonium ion concentration Journal of the American Society For Mass Spectrometry. 8: 155-160. DOI: 10.1016/S1044-0305(96)00200-0  1
1997 Peoc'h D, Swayze EE, Bhat B, Dimock S, Griffey R, Sanghvi YS. Synthesis and evaluation of 2'-modified MMI linked dimers in antisense constructs Nucleosides and Nucleotides. 16: 959-962.  1
1997 Ross BS, Vasquez G, Manalili S, Lesnik E, Griffey R. Synthesis and incorporation of 2'-O-methyl-pseudouridine into oligonucleotides Nucleosides and Nucleotides. 16: 1547-1549.  1
1997 Lesnik E, Hassman F, Barbeau J, Teng K, Weiler K, Griffey R, Freier S. Triplex formation between DNA and mixed purine-pyrimidine PNA analog with lysines in backbone Nucleosides and Nucleotides. 16: 1775-1779.  1
1996 Griffey RH, Monia BP, Cummins LL, Freier S, Greig MJ, Guinosso CJ, Lesnik E, Manalili SM, Mohan V, Owens S, Ross BR, Sasmor H, Wancewicz E, Weiler K, Wheeler PD, et al. 2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. Journal of Medicinal Chemistry. 39: 5100-9. PMID 8978841 DOI: 10.1021/jm950937o  1
1996 Bartlett MG, McCloskey JA, Manalili S, Griffey RH. The effect of backbone charge on the collision-induced dissociation of oligonucleotides. Journal of Mass Spectrometry : Jms. 31: 1277-83. PMID 8946735 DOI: 10.1002/(SICI)1096-9888(199611)31:11<1277::AID-JMS418>3.0.CO;2-F  1
1996 Eaton RP, Qualls C, Bicknell J, Sibbitt WL, King MK, Griffey RH. Structure-function relationships within peripheral nerves in diabetic neuropathy: the hydration hypothesis. Diabetologia. 39: 439-46. PMID 8777993 DOI: 10.1007/s001250050463  1
1996 White AP, Reeves KK, Snyder E, Farrell J, Powell JW, Mohan V, Griffey RH. Hydration of single-stranded phosphodiester and phosphorothioate oligodeoxyribonucleotides. Nucleic Acids Research. 24: 3261-6. PMID 8774910  1
1996 Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornbrust D, Manoharan M, Sasmor HM, Schleich T, Tivel KL, Griffey RH. Pharmacokinetic properties of several novel oligonucleotide analogs in mice Journal of Pharmacology and Experimental Therapeutics. 277: 923-937. PMID 8627575  1
1996 Greig MJ, Gaus HJ, Griffey RH. Negative ionization micro electrospray mass spectrometry of oligonucleotides and their complexes. Rapid Communications in Mass Spectrometry : Rcm. 10: 47-50. PMID 8563016 DOI: 10.1002/(SICI)1097-0231(19960115)10:1<47::AID-RCM436>3.0.CO;2-M  1
1995 Crooke ST, Lemonidis KM, Neilson L, Griffey R, Lesnik EA, Monia BP. Kinetic characteristics of Escherichia coli RNase H1: Cleavage of various antisense oligonucleotide-RNA duplexes Biochemical Journal. 312: 599-608. PMID 8526876  1
1995 Greig M, Griffey RH. Utility of organic bases for improved electrospray mass spectrometry of oligonucleotides. Rapid Communications in Mass Spectrometry : Rcm. 9: 97-102. PMID 7888709 DOI: 10.1002/rcm.1290090121  1
1995 Sibbitt WL, Brooks WM, Haseler LJ, Griffey RH, Frank LM, Hart BL, Sibbitt RR. Spin-spin relaxation of brain tissues in systemic lupus erythematosus. A method for increasing the sensitivity of magnetic resonance imaging for neuropsychiatric lupus. Arthritis and Rheumatism. 38: 810-8. PMID 7779125 DOI: 10.1002/art.1780380615  1
1995 Griffith MC, Risen LM, Greig MJ, Lesnik EA, Sprankle KG, Griffey RH, Kiely JS, Freier SM. Single and bis peptide nucleic acids as triplexing agents: Binding and stoichiometry Journal of the American Chemical Society. 117: 831-832. DOI: 10.1021/ja00107a033  1
1995 Mohan V, Griffey RH, Davis DR. Structure and dynamics of MMI linked nucleotides Tetrahedron. 51: 6855-6868. DOI: 10.1016/0040-4020(95)00333-4  1
1995 Perbost M, Hoshiko T, Morvan F, Swayze E, Griffey RH, Sanghvi YS. Synthesis of 5′-O-amino-2′-deoxypyrimidine and purine nucleosides: Building-blocks for antisense oligonucleosides The Journal of Organic Chemistry. 60: 5150-5156.  1
1995 Greig MJ, Gaus H, Cummins LL, Sasmor H, Griffey RH. Measurement of macromolecular binding using electrospray mass spectrometry. Determination of dissociation constants for oligonucleotide-serum albumin complexes Journal of the American Chemical Society. 117: 10765-10766.  1
1995 Sanghvi YS, Bellon L, Morvan F, Hoshiko T, Swayze E, Cummins L, Freier S, Dean N, Monia B, Griffey RH, Cook PD. Synthesis, biophysical and biological evaluations of novel antisense oligonucleosides containing dephosphono-internucleosidic linkages Nucleosides and Nucleotides. 14: 1087-1090.  1
1994 Sibbitt WL, Haseler LJ, Griffey RH, Hart BL, Sibbitt RR, Matwiyoff NA. Analysis of cerebral structural changes in systemic lupus erythematosus by proton MR spectroscopy. Ajnr. American Journal of Neuroradiology. 15: 923-8. PMID 8059662  1
1994 Griffey RH, Sibbitt WL, Sibbitt RR, Griffey BV, Eaton RP, Hunsaker LA, Vander Jagt DL. Polyol and water accumulation in muscle of galactose-fed rats. Biochemical Pharmacology. 48: 1839-41. PMID 7980654 DOI: 10.1016/0006-2952(94)90471-5  1
1994 Chen SM, Mohan V, Kiely JS, Griffith MC, Griffey RH. Molecular dynamics and NMR studies of single-stranded PNAs Tetrahedron Letters. 35: 5105-5108. DOI: 10.1016/S0040-4039(00)77039-0  1
1994 Ramasamy KS, Zounes M, Gonzalez C, Freier SM, Lesnik EA, Cummins LL, Griffey RH, Monia BP, Dan Cook P. Remarkable enhancement of binding affinity of Heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N2-imidazolylpropylguanine and N2-imidazolylpropyl-2-aminoadenine modified oligonucleotides Tetrahedron Letters. 35: 215-218. DOI: 10.1016/S0040-4039(00)76514-2  1
1993 Eaton RP, Sibbitt WL, Bicknell JM, King MK, Griffey RH, Sibbitt RR. Sural nerve water in vivo in normal humans measured by magnetic resonance spectroscopy: relation to age, height, gender, and neurological profile. Muscle & Nerve. 16: 307-11. PMID 8446130 DOI: 10.1002/mus.880160311  1
1992 Yaquinto JJ, Harms SE, Siemers PT, Flamig DP, Griffey RH, Foreman ML. Arterial injury from penetrating trauma: evaluation with single-acquisition fat-suppressed MR imaging. Ajr. American Journal of Roentgenology. 158: 631-3. PMID 1739008 DOI: 10.2214/ajr.158.3.1739008  1
1992 Flamig DP, Pierce WB, Harms SE, Griffey RH. Magnetization transfer contrast in fat-suppressed steady-state three-dimensional MR images. Magnetic Resonance in Medicine. 26: 122-31. PMID 1625559 DOI: 10.1002/mrm.1910260113  1
1992 Mann PL, Busse SC, Griffey RH, Laubscher K. Cell surface oligosaccharide modulation during differentiation: VI. The effect of biomodulation on the senescent and neoplastic cell phenotype. Mechanisms of Ageing and Development. 62: 79-110. PMID 1560684 DOI: 10.1016/0047-6374(92)90144-3  1
1992 Mann PL, Busse SC, Griffey RH, Tellez CM. Cell surface oligosaccharide modulation during differentiation: V. Partial characterization of the regulated surface during substrate adhesion and spreading. Mechanisms of Ageing and Development. 62: 47-77. PMID 1560683 DOI: 10.1016/0047-6374(92)90143-2  1
1992 Ford CC, Griffey RH, Matwiyoff NA, Rosenberg GA. Multivoxel 1H-MRS of stroke. Neurology. 42: 1408-12. PMID 1320220  1
1991 Pierce WB, Harms SE, Flamig DP, Griffey RH, Evans WP, Hagans JE. Three-dimensional gadolinium-enhanced MR imaging of the breast: pulse sequence with fat suppression and magnetization transfer contrast. Work in progress. Radiology. 181: 757-63. PMID 1947093 DOI: 10.1148/radiology.181.3.1947093  1
1991 Rosenberg GA, White J, Gasparovic C, Crisostomo EA, Griffey RH. Effect of hypoxia on cerebral metabolites measured by proton nuclear magnetic resonance spectroscopy in rats. Stroke; a Journal of Cerebral Circulation. 22: 73-9. PMID 1846248  1
1991 Vinitski S, Griffey RH. MR image contrast at high field strength. Journal of Magnetic Resonance Imaging : Jmri. 1: 451-6. PMID 1790367  1
1991 Vinitski S, Mitchell DG, Griffey RH, Ortega HV, Mohamed F, Rifkin MD. Image contrast in gradient and spin-echo MRI as a function of field strength Proceedings of the Annual Conference On Engineering in Medicine and Biology. 13: 118-120.  1
1990 Caprihan A, Griffey RH, Fukushima E. Velocity imaging of slow coherent flows using stimulated echoes. Magnetic Resonance in Medicine. 15: 327-33. PMID 2392055 DOI: 10.1002/mrm.1910150214  1
1990 Griffey RH, Brown MS, Bankhurst AD, Sibbitt RR, Sibbitt WL. Depletion of high-energy phosphates in the central nervous system of patients with systemic lupus erythematosus, as determined by phosphorus-31 nuclear magnetic resonance spectroscopy. Arthritis and Rheumatism. 33: 827-33. PMID 2363738 DOI: 10.1002/art.1780330609  1
1990 Griffey RH, Griffey BV, Matwiyoff NA. Triple-quantum-coherence-filtered imaging of sodium ions in vivo at 4.7 tesla. Magnetic Resonance in Medicine. 13: 305-13. PMID 2314219  1
1990 Griffey RH, P. Flamig D. VAPOR for solvent-suppressed, short-echo, volume-localized proton spectroscopy Journal of Magnetic Resonance (1969). 88: 161-166. DOI: 10.1016/0022-2364(90)90120-X  1
1990 Abousleman GP, Jordan R, Asgharzadeh A, Canady LD, Koechner D, Griffey RH. A novel eigenvector-based technique for spectral estimation of time-domain data in medical imaging . 426-431.  1
1990 Canady LD, Jordan R, Asgharzadeh A, Abousleman G, Koechner D, Griffey RH. Time-domain analysis of magnetic resonance spectra and chemical shift images . 432-437.  1
1990 Asgharzadeh A, Jordan R, Abousleman G, Canady LD, Koechner D, Griffey RH. Applications of adaptive analysis in magnetic resonance imaging . 75-80.  1
1989 Busse SC, Mann PL, Griffey RH. Senescence-induced alteration in cell surface carbohydrates correlated using proton NMR spectroscopy and a lectin-based affinity-binding assay. Biochimica Et Biophysica Acta. 984: 183-7. PMID 2765547 DOI: 10.1016/0005-2736(89)90214-9  1
1989 Martin JF, Guth BD, Griffey RH, Hoekenga DE. Myocardial creatine kinase exchange rates and 31P NMR relaxation rates in intact pigs. Magnetic Resonance in Medicine. 11: 64-72. PMID 2747517  1
1989 Sibbitt WL, Sibbitt RR, Griffey RH, Eckel C, Bankhurst AD. Magnetic resonance and computed tomographic imaging in the evaluation of acute neuropsychiatric disease in systemic lupus erythematosus. Annals of the Rheumatic Diseases. 48: 1014-22. PMID 2619353 DOI: 10.1136/ard.48.12.1014  1
1989 Griffey RH. Tumor characterization using unconventional MR modalities. Investigative Radiology. 24: 985-7. PMID 2558089  1
1989 Griffey RH. Carbon-13 magnetic resonance spectroscopy. Problems and promise. Investigative Radiology. 24: 1017-9. PMID 2558084  1
1989 Sibbitt WL, Mills RG, Bigler CF, Eaton RP, Griffey RH, Vander Jagt DL. Glucose inhibition of human fibroblast proliferation and response to growth factors is prevented by inhibitors of aldose reductase. Mechanisms of Ageing and Development. 47: 265-79. PMID 2497284 DOI: 10.1016/0047-6374(89)90038-9  1
1988 Nakada T, Kwee IL, Card PJ, Matwiyoff NA, Griffey BV, Griffey RH. Fluorine-19 NMR imaging of glucose metabolism. Magnetic Resonance in Medicine. 6: 307-13. PMID 3362066  1
1988 Nakada T, Kwee IL, Griffey BV, Griffey RH. 19F 2-FDG NMR imaging of the brain in rat. Magnetic Resonance Imaging. 6: 633-5. PMID 3210906 DOI: 10.1016/0730-725X(88)90085-9  1
1988 Griffey RH, Scavini M, Eaton RP. Characterization of the carbamino adducts of insulin. Biophysical Journal. 54: 295-300. PMID 3145039 DOI: 10.1016/S0006-3495(88)82959-X  1
1988 Griffey RH, Eaton RP, Sibbitt RR, Sibbitt WL, Bicknell JM. Diabetic neuropathy. Structural analysis of nerve hydration by magnetic resonance spectroscopy. Jama. 260: 2872-8. PMID 3141635 DOI: 10.1001/jama.1988.03410190120034  1
1988 Nakada T, Kwee IL, Griffey BV, Griffey RH. F-19 MR imaging of glucose metabolism in the rabbit. Radiology. 168: 823-5. PMID 3136509 DOI: 10.1148/radiology.168.3.3136509  1
1988 Vinitski S, Griffey RH, Szumowski J, Matwiyoff NA. Lactate observation in vivo by spectral editing in real time. Magnetic Resonance Imaging. 6: 707-11. PMID 3062299 DOI: 10.1016/0730-725X(88)90095-1  1
1988 Sillerud LO, Halliday KR, Griffey RH, Fenoglio-Preiser C, Sheppard S. In vivo 13C NMR spectroscopy of the human prostate. Magnetic Resonance in Medicine. 8: 224-30. PMID 2463457  1
1988 Sillerud LO, Van Hulsteyn DB, Griffey RH. {13C}-polarization transfer proton NMR imaging of a sodium [13C]formate phantom at 4.7 tesla Journal of Magnetic Resonance (1969). 76: 380-385. DOI: 10.1016/0022-2364(88)90126-6  1
1987 Griffey RH, Eaton RP, Gasparovic C, Sibbitt W. Galactose neuropathy. Structural changes evaluated by nuclear magnetic resonance spectroscopy. Diabetes. 36: 776-8. PMID 3032717  1
1987 McIntosh LP, Griffey RH, Muchmore DC, Nielson CP, Redfield AG, Dahlquist FW. Proton NMR measurements of bacteriophage T4 lysozyme aided by 15N isotopic labeling: structural and dynamic studies of larger proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 1244-8. PMID 3029773 DOI: 10.1073/pnas.84.5.1244  1
1987 Griffey RH, Redfield AG. Proton-detected heteronuclear edited and correlated nuclear magnetic resonance and nuclear Overhauser effect in solution. Quarterly Reviews of Biophysics. 19: 51-82. PMID 2819934  1
1986 Griffey RH, Davis DR, Yamaizumi Z, Nishimura S, Hawkins BL, Poulter CD. 15N-labeled tRNA. Identification of 4-thiouridine in Escherichia coli tRNASer1 and tRNATyr2 by 1H-15N two-dimensional NMR spectroscopy. The Journal of Biological Chemistry. 261: 12074-8. PMID 3638307  1
1986 Davis DR, Griffey RH, Yamaizumi Z, Nishimura S, Poulter CD. 15N-labeled tRNA. Identification of dihydrouridine in Escherichia coli tRNAfMet, tRNALys, and tRNAPhe by 1H-15N two-dimensional NMR. The Journal of Biological Chemistry. 261: 3584-7. PMID 3512560  1
1986 Weiss MA, Redfield AG, Griffey RH. Isotope-detected 1H NMR studies of proteins: a general strategy for editing interproton nuclear Overhauser effects by heteronuclear decoupling, with application to phage lambda repressor. Proceedings of the National Academy of Sciences of the United States of America. 83: 1325-9. PMID 3006046  1
1986 Griffey RH, Redfield AG, McIntosh LP, Oas TG, Dahlquist FW. Assignment of proton amide resonances of T4 lysozyme by 13C and 15N multiple isotopic labeling Journal of the American Chemical Society. 108: 6816-6817.  1
1985 Griffey RH, Davis D, Yamaizumi Z, Nishimura S, Bax A, Hawkins B, Poulter CD. 15N-labeled Escherichia coli tRNAfMet, tRNAGlu, tRNATyr, and tRNAPhe. Double resonance and two-dimensional NMR of N1-labeled pseudouridine. The Journal of Biological Chemistry. 260: 9734-41. PMID 3894360  1
1985 Griffey RH, Redfield AG, Loomis RE, Dahlquist FW. Nuclear magnetic resonance observation and dynamics of specific amide protons in T4 lysozyme. Biochemistry. 24: 817-22. PMID 3888265  1
1985 Griffey RH, Redfield AG. Identification of isotope-labeled resonances in two-dimensional proton-proton correlation and exchange spectroscopy with gated heteronuclear decoupling Journal of Magnetic Resonance (1969). 65: 344-347. DOI: 10.1016/0022-2364(85)90016-2  1
1985 Griffey RH, Jarema MA, Kunz S, Rosevear PR, Redfield AG. Isotopic-label-directed observation of the nuclear Overhauser effect in poorly resolved proton NMR spectra Journal of the American Chemical Society. 107: 711-712.  1
1983 Griffey RH, Poulter CD. Efficient syntheses of [3-15N]uracil and [3-15N]thymine. Nucleic Acids Research. 11: 6497-504. PMID 6622258 DOI: 10.1093/nar/11.18.6497  1
1983 Griffey RH, Poulter CD, Bax A, Hawkins BL, Yamaizumi Z, Nishimura S. Multiple quantum two-dimensional 1H--15N nuclear magnetic resonance spectroscopy: chemical shift correlation maps for exchangeable imino protons of Escherichia coli tRNAMetf in water. Proceedings of the National Academy of Sciences of the United States of America. 80: 5895-7. PMID 6351069  1
1983 Griffey RH, Poulter CD. Detection of the imino hydrogen bond in GC pairs by 1H and 15N nuclear magnetic resonance spectroscopy Tetrahedron Letters. 24: 4067-4070. DOI: 10.1016/S0040-4039(00)88263-5  1
1983 Bax A, Griffey RH, Hawkins BL. Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR Journal of Magnetic Resonance (1969). 55: 301-315. DOI: 10.1016/0022-2364(83)90241-X  1
1983 Griffey RH, Poulter CD, Yamaizumi Z, Nishimura S, Hawkins BL. 1H NMR studies of nitrogen-15-labeled Escbericbia coli tRNAf Met. Assignments of imino resonances for uridine-related bases by 1H-15N heteronuclear double resonance difference spectroscopy Journal of the American Chemical Society. 105: 143-145.  1
1983 Gueron M, Leroy JL, Griffey RH. PROTON NUCLEAR MAGNETITE RELAXATION OF **1**5N-LABELED NUCLEIC ACIDS VIA DIPOLAR COUPLING AND CHEMICAL SHIFT ANISOTROPY Journal of the American Chemical Society. 105: 7262-7266.  1
1983 Bax A, Griffey RH, Hawkins BL. Sensitivity-enhanced correlation of 15N and 1H chemical shifts in natural-abundance samples via multiple quantum coherence Journal of the American Chemical Society. 105: 7188-7190.  1
1982 Griffey RH, Poulter CD, Yamaizumi Z, Nishimura S, Hurd RE. 1H NMR studies of 15N-labeled Escherichia coli tRNAfMet. An unambiguous assignment for the G-U pair and detection of a uridine resonance at 11.4 ppm Journal of the American Chemical Society. 104: 5811-5813.  1
1982 Griffey RH, Poulter CD, Yamaizumi Z, Nishimura S, Hurd RE. 1H NMR studies of 15N-labeled Escherichia coli tRNAf Met. Use of 1J1H-15N couplings to identify imino resonances of undine-related bases Journal of the American Chemical Society. 104: 5810-5811.  1
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