Hakon Leffler - Publications

1984-1990 University of California, San Diego, La Jolla, CA 

184 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, Nilsson UJ, Leffler H, Poirier F, Terzi F, Delacour D. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Scientific Reports. 7: 1474. PMID 28469279 DOI: 10.1038/s41598-017-01614-6  0.6
2016 Chen WS, Cao Z, Sugaya S, Lopez MJ, Sendra VG, Laver N, Leffler H, Nilsson UJ, Fu J, Song J, Xia L, Hamrah P, Panjwani N. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nature Communications. 7: 11302. PMID 27066737 DOI: 10.1038/ncomms11302  0.96
2016 Ippel H, Miller MC, Vértesy S, Zhang Y, Cañada FJ, Suylen D, Umemoto K, Romanò C, Hackeng T, Tai G, Leffler H, Kopitz J, André S, Kübler D, Jiménez-Barbero J, et al. Intra- and inter-molecular interactions of human galectin-3: assessment by full-assignment-based NMR. Glycobiology. PMID 26911284 DOI: 10.1093/glycob/cww021  0.96
2016 Block M, Mölne J, Leffler H, Börjesson L, Breimer ME. Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis. Biomed Research International. 2016: 5989128. PMID 26885508 DOI: 10.1155/2016/5989128  0.96
2016 Bum-Erdene K, Leffler H, Nilsson UJ, Blanchard H. Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose. Scientific Reports. 6: 20289. PMID 26828567 DOI: 10.1038/srep20289  0.96
2015 Bum-Erdene K, Leffler H, Nilsson UJ, Blanchard H. Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens. The Febs Journal. PMID 26077389 DOI: 10.1111/febs.13348  0.96
2015 Burguillos MA, Svensson M, Schulte T, Boza-Serrano A, Garcia-Quintanilla A, Kavanagh E, Santiago M, Viceconte N, Oliva-Martin MJ, Osman AM, Salomonsson E, Amar L, Persson A, Blomgren K, Achour A, ... ... Leffler H, et al. Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation. Cell Reports. PMID 25753426 DOI: 10.1016/j.celrep.2015.02.012  0.96
2015 Volarevic V, Markovic BS, Bojic S, Stojanovic M, Nilsson U, Leffler H, Besra GS, Arsenijevic N, Paunovic V, Trajkovic V, Lukic ML. Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury. European Journal of Immunology. 45: 531-43. PMID 25359399 DOI: 10.1002/eji.201444849  0.96
2015 Mackinnon A, Chen WS, Leffler H, Panjwani N, Schambye H, Sethi T, Nilsson UJ. Design, synthesis, And applications of galectin modulators in human health Topics in Medicinal Chemistry. 12: 95-122. DOI: 10.1007/7355_2014_49  0.96
2014 Boza-Serrano A, Reyes JF, Rey NL, Leffler H, Bousset L, Nilsson U, Brundin P, Venero JL, Burguillos MA, Deierborg T. The role of Galectin-3 in α-synuclein-induced microglial activation. Acta Neuropathologica Communications. 2: 156. PMID 25387690 DOI: 10.1186/s40478-014-0156-0  0.96
2014 Rajput VK, Leffler H, Nilsson UJ, Mukhopadhyay B. Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists. Bioorganic & Medicinal Chemistry Letters. 24: 3516-20. PMID 24973029 DOI: 10.1016/j.bmcl.2014.05.063  0.96
2014 von Mach T, Carlsson MC, Straube T, Nilsson U, Leffler H, Jacob R. Ligand binding and complex formation of galectin-3 is modulated by pH variations. The Biochemical Journal. 457: 107-15. PMID 24147723 DOI: 10.1042/BJ20130933  0.96
2014 Mackeviča J, Ostrovskis P, Leffler H, Nilsson UJ, Rudovica V, Viksna A, Belyakov S, Turks M. Synthesis of 1,2,3-triazole-linked galactohybrids and their inhibitory activities on galectins Arkivoc. 2014: 90-112. DOI: 10.3998/ark.5550190.p008.402  0.96
2013 Carlsson MC, Bengtson P, Cucak H, Leffler H. Galectin-3 guides intracellular trafficking of some human serotransferrin glycoforms. The Journal of Biological Chemistry. 288: 28398-408. PMID 23926108 DOI: 10.1074/jbc.M113.487793  0.96
2013 Bum-Erdene K, Gagarinov IA, Collins PM, Winger M, Pearson AG, Wilson JC, Leffler H, Nilsson UJ, Grice ID, Blanchard H. Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors. Chembiochem : a European Journal of Chemical Biology. 14: 1331-42. PMID 23864426 DOI: 10.1002/cbic.201300245  0.96
2013 van Hattum H, Branderhorst HM, Moret EE, Nilsson UJ, Leffler H, Pieters RJ. Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. Journal of Medicinal Chemistry. 56: 1350-4. PMID 23281927 DOI: 10.1021/jm301677r  0.96
2013 Saksida T, Nikolic I, Vujicic M, Nilsson UJ, Leffler H, Lukic ML, Stojanovic I, Stosic-Grujicic S. Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro. Journal of Cellular Physiology. 228: 1568-76. PMID 23280610 DOI: 10.1002/jcp.24318  0.96
2012 Breimer ME, Hansson GC, Karlsson KA, Larson G, Leffler H. Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual. Glycobiology. 22: 1721-30. PMID 22833314 DOI: 10.1093/glycob/cws115  0.96
2012 Lepur A, Salomonsson E, Nilsson UJ, Leffler H. Ligand induced galectin-3 protein self-association. The Journal of Biological Chemistry. 287: 21751-6. PMID 22549776 DOI: 10.1074/jbc.C112.358002  0.96
2012 Lepur A, Carlsson MC, Novak R, Dumi? J, Nilsson UJ, Leffler H. Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types. Biochimica Et Biophysica Acta. 1820: 804-18. PMID 22450157 DOI: 10.1016/j.bbagen.2012.02.018  0.96
2012 Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H. Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease. Biochimica Et Biophysica Acta. 1820: 1366-72. PMID 22285770 DOI: 10.1016/j.bbagen.2012.01.007  0.96
2012 Cederfur C, Malmström J, Nihlberg K, Block M, Breimer ME, Bjermer L, Westergren-Thorsson G, Leffler H. Glycoproteomic identification of galectin-3 and -8 ligands in bronchoalveolar lavage of mild asthmatics and healthy subjects. Biochimica Et Biophysica Acta. 1820: 1429-36. PMID 22240167 DOI: 10.1016/j.bbagen.2011.12.016  0.96
2012 Volarevic V, Milovanovic M, Ljujic B, Pejnovic N, Arsenijevic N, Nilsson U, Leffler H, Lukic ML. Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice. Hepatology (Baltimore, Md.). 55: 1954-64. PMID 22213244 DOI: 10.1002/hep.25542  0.96
2012 Carlsson MC, Bakoush O, Tengroth L, Kilsgård O, Malmström J, Hellmark T, Segelmark M, Leffler H. Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins. Journal of Clinical Immunology. 32: 246-55. PMID 22173878 DOI: 10.1007/s10875-011-9618-3  0.96
2012 Collins PM, Oberg CT, Leffler H, Nilsson UJ, Blanchard H. Taloside inhibitors of galectin-1 and galectin-3. Chemical Biology & Drug Design. 79: 339-46. PMID 22136701 DOI: 10.1111/j.1747-0285.2011.01283.x  0.96
2012 Saraboji K, HÃ¥kansson M, Genheden S, Diehl C, Qvist J, Weininger U, Nilsson UJ, Leffler H, Ryde U, Akke M, Logan DT. The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics. Biochemistry. 51: 296-306. PMID 22111949 DOI: 10.1021/bi201459p  0.96
2012 Mackinnon AC, Gibbons MA, Farnworth SL, Leffler H, Nilsson UJ, Delaine T, Simpson AJ, Forbes SJ, Hirani N, Gauldie J, Sethi T. Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. American Journal of Respiratory and Critical Care Medicine. 185: 537-46. PMID 22095546 DOI: 10.1164/rccm.201106-0965OC  0.96
2012 Masuyer G, Jabeen T, Öberg CT, Leffler H, Nilsson UJ, Acharya KR. Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor. The Febs Journal. 279: 193-202. PMID 22059385 DOI: 10.1111/j.1742-4658.2011.08414.x  0.96
2012 Leffler H, Nilsson UJ. Low-molecular weight inhibitors of galectins Acs Symposium Series. 1115: 47-59. DOI: 10.1021/bk-2012-1115.ch002  0.96
2011 Carlsson MC, Cederfur C, Schaar V, Balog CI, Lepur A, Touret F, Salomonsson E, Deelder AM, Fernö M, Olsson H, Wuhrer M, Leffler H. Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients. Plos One. 6: e26560. PMID 22028908 DOI: 10.1371/journal.pone.0026560  0.96
2011 Öberg CT, Noresson AL, Leffler H, Nilsson UJ. Arene-anion based arginine-binding motif on a galactose scaffold: structure-activity relationships of interactions with arginine-rich galectins. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 8139-44. PMID 21656580 DOI: 10.1002/chem.201003247  0.96
2011 Oberg CT, Leffler H, Nilsson UJ. Inhibition of galectins with small molecules. Chimia. 65: 18-23. PMID 21469439 DOI: 10.2533/chimia.2011.18  0.96
2011 Salomonsson E, Thijssen VL, Griffioen AW, Nilsson UJ, Leffler H. The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins. The Journal of Biological Chemistry. 286: 13801-4. PMID 21372130 DOI: 10.1074/jbc.C111.229096  0.96
2011 Öberg CT, Noresson AL, Leffler H, Nilsson UJ. Synthesis of 3-amido-3-deoxy-β-d-talopyranosides: All-cis-substituted pyranosides as lectin inhibitors Tetrahedron. 67: 9164-9172. DOI: 10.1016/j.tet.2011.09.098  0.96
2010 Diehl C, Engström O, Delaine T, Håkansson M, Genheden S, Modig K, Leffler H, Ryde U, Nilsson UJ, Akke M. Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3. Journal of the American Chemical Society. 132: 14577-89. PMID 20873837 DOI: 10.1021/ja105852y  0.96
2010 Salomonsson E, Larumbe A, Tejler J, Tullberg E, Rydberg H, Sundin A, Khabut A, Frejd T, Lobsanov YD, Rini JM, Nilsson UJ, Leffler H. Monovalent interactions of galectin-1. Biochemistry. 49: 9518-32. PMID 20873803 DOI: 10.1021/bi1009584  0.96
2010 Stannard KA, Collins PM, Ito K, Sullivan EM, Scott SA, Gabutero E, Darren Grice I, Low P, Nilsson UJ, Leffler H, Blanchard H, Ralph SJ. Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. Cancer Letters. 299: 95-110. PMID 20826047 DOI: 10.1016/j.canlet.2010.08.005  0.96
2010 Salomonsson E, Carlsson MC, Osla V, Hendus-Altenburger R, Kahl-Knutson B, Oberg CT, Sundin A, Nilsson R, Nordberg-Karlsson E, Nilsson UJ, Karlsson A, Rini JM, Leffler H. Mutational tuning of galectin-3 specificity and biological function. The Journal of Biological Chemistry. 285: 35079-91. PMID 20807768 DOI: 10.1074/jbc.M109.098160  0.96
2010 Gouin SG, García Fernández JM, Vanquelef E, Dupradeau FY, Salomonsson E, Leffler H, Ortega-Muñoz M, Nilsson UJ, Kovensky J. Multimeric lactoside "click clusters" as tools to investigate the effect of linker length in specific interactions with peanut lectin, galectin-1, and -3. Chembiochem : a European Journal of Chemical Biology. 11: 1430-42. PMID 20549756 DOI: 10.1002/cbic.201000167  0.96
2010 Salameh BA, Cumpstey I, Sundin A, Leffler H, Nilsson UJ. 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorganic & Medicinal Chemistry. 18: 5367-78. PMID 20538469 DOI: 10.1016/j.bmc.2010.05.040  0.96
2010 Paz I, Sachse M, Dupont N, Mounier J, Cederfur C, Enninga J, Leffler H, Poirier F, Prevost MC, Lafont F, Sansonetti P. Galectin-3, a marker for vacuole lysis by invasive pathogens. Cellular Microbiology. 12: 530-44. PMID 19951367 DOI: 10.1111/j.1462-5822.2009.01415.x  0.96
2010 Rini JM, Leffler H. Carbohydrate recognition and signaling Handbook of Cell Signaling, 2/E. 1: 85-91. DOI: 10.1016/B978-0-12-374145-5.00013-9  0.96
2010 Oberg CT, Leffler H, Nilsson UJ. Copper-free huisgen 1,3-dipolar cycloaddition to 3-benzotriazolo-3-deoxy-β-D-galactopyranoside: Cyclization of a galactopyranoside azide and benzyne Trends in Carbohydrate Research. 2: 1-4.  0.96
2009 Lin CI, Whang EE, Donner DB, Jiang X, Price BD, Carothers AM, Delaine T, Leffler H, Nilsson UJ, Nose V, Moore FD, Ruan DT. Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer. Molecular Cancer Research : McR. 7: 1655-62. PMID 19825987 DOI: 10.1158/1541-7786.MCR-09-0274  0.96
2009 Tejler J, Salameh B, Leffler H, Nilsson UJ. Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3. Organic & Biomolecular Chemistry. 7: 3982-90. PMID 19763301 DOI: 10.1039/b909091f  0.96
2009 van Scherpenzeel M, Moret EE, Ballell L, Liskamp RM, Nilsson UJ, Leffler H, Pieters RJ. Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3. Chembiochem : a European Journal of Chemical Biology. 10: 1724-33. PMID 19492387 DOI: 10.1002/cbic.200900198  0.96
2009 Jendholm J, Mörgelin M, Perez Vidakovics ML, Carlsson M, Leffler H, Cardell LO, Riesbeck K. Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 4713-20. PMID 19342647 DOI: 10.4049/jimmunol.0803032  0.96
2009 Diskin S, Cao Z, Leffler H, Panjwani N. The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology. 19: 29-37. PMID 18849583 DOI: 10.1093/glycob/cwn100  0.96
2009 Karlsson A, Christenson K, Matlak M, Björstad A, Brown KL, Telemo E, Salomonsson E, Leffler H, Bylund J. Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils. Glycobiology. 19: 16-20. PMID 18849325 DOI: 10.1093/glycob/cwn104  0.96
2008 Delaine T, Cumpstey I, Ingrassia L, Le Mercier M, Okechukwu P, Leffler H, Kiss R, Nilsson UJ. Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells. Journal of Medicinal Chemistry. 51: 8109-14. PMID 19053747 DOI: 10.1021/jm801077j  0.96
2008 Forsman H, Salomonsson E, Onnheim K, Karlsson J, Björstad A, Leffler H, Bylund J, Karlsson A, Dahlgren C. The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. Glycobiology. 18: 905-12. PMID 18725453 DOI: 10.1093/glycob/cwn081  0.96
2008 Oberg CT, Blanchard H, Leffler H, Nilsson UJ. Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8. Bioorganic & Medicinal Chemistry Letters. 18: 3691-4. PMID 18539029 DOI: 10.1016/j.bmcl.2008.05.066  0.96
2008 Cumpstey I, Salomonsson E, Sundin A, Leffler H, Nilsson UJ. Double affinity amplification of galectin-ligand interactions through arginine-arene interactions: synthetic, thermodynamic, and computational studies with aromatic diamido thiodigalactosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4233-45. PMID 18366047 DOI: 10.1002/chem.200701932  0.96
2008 Oberg CT, Leffler H, Nilsson UJ. Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors. Journal of Medicinal Chemistry. 51: 2297-301. PMID 18318467 DOI: 10.1021/jm701266y  0.96
2008 Stowell SR, Qian Y, Karmakar S, Koyama NS, Dias-Baruffi M, Leffler H, McEver RP, Cummings RD. Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion. Journal of Immunology (Baltimore, Md. : 1950). 180: 3091-102. PMID 18292532  0.96
2008 Cederfur C, Salomonsson E, Nilsson J, Halim A, Oberg CT, Larson G, Nilsson UJ, Leffler H. Different affinity of galectins for human serum glycoproteins: galectin-3 binds many protease inhibitors and acute phase proteins. Glycobiology. 18: 384-94. PMID 18263896 DOI: 10.1093/glycob/cwn015  0.96
2008 MacKinnon AC, Farnworth SL, Hodkinson PS, Henderson NC, Atkinson KM, Leffler H, Nilsson UJ, Haslett C, Forbes SJ, Sethi T. Regulation of alternative macrophage activation by galectin-3. Journal of Immunology (Baltimore, Md. : 1950). 180: 2650-8. PMID 18250477  0.96
2008 Stowell SR, Arthur CM, Mehta P, Slanina KA, Blixt O, Leffler H, Smith DF, Cummings RD. Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens. The Journal of Biological Chemistry. 283: 10109-23. PMID 18216021 DOI: 10.1074/jbc.M709545200  0.96
2007 Bax M, García-Vallejo JJ, Jang-Lee J, North SJ, Gilmartin TJ, Hernández G, Crocker PR, Leffler H, Head SR, Haslam SM, Dell A, van Kooyk Y. Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8216-24. PMID 18056365  0.96
2007 Cumpstey I, Salomonsson E, Sundin A, Leffler H, Nilsson UJ. Studies of arginine-arene interactions through synthesis and evaluation of a series of galectin-binding aromatic lactose esters. Chembiochem : a European Journal of Chemical Biology. 8: 1389-98. PMID 17631664 DOI: 10.1002/cbic.200700040  0.96
2007 Carlsson S, Carlsson MC, Leffler H. Intracellular sorting of galectin-8 based on carbohydrate fine specificity. Glycobiology. 17: 906-12. PMID 17580315 DOI: 10.1093/glycob/cwm059  0.96
2007 Gustavsson P, Linsmeier CE, Leffler H, Kanje M. Galectin-3 inhibits Schwann cell proliferation in cultured sciatic nerve. Neuroreport. 18: 669-73. PMID 17426596 DOI: 10.1097/WNR.0b013e3280bef97b  0.96
2007 Tejler J, Skogman F, Leffler H, Nilsson UJ. Synthesis of galactose-mimicking 1H-(1,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors. Carbohydrate Research. 342: 1869-75. PMID 17407769 DOI: 10.1016/j.carres.2007.03.012  0.96
2007 Carlsson S, Oberg CT, Carlsson MC, Sundin A, Nilsson UJ, Smith D, Cummings RD, Almkvist J, Karlsson A, Leffler H. Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface. Glycobiology. 17: 663-76. PMID 17339281 DOI: 10.1093/glycob/cwm026  0.96
2007 Delacour D, Greb C, Koch A, Salomonsson E, Leffler H, Le Bivic A, Jacob R. Apical sorting by galectin-3-dependent glycoprotein clustering. Traffic (Copenhagen, Denmark). 8: 379-88. PMID 17319896 DOI: 10.1111/j.1600-0854.2007.00539.x  0.96
2007 Eriksson C, Frängsmyr L, Danielsson Niemi L, Loimaranta V, Holmskov U, Bergman T, Leffler H, Jenkinson HF, Strömberg N. Variant size- and glycoforms of the scavenger receptor cysteine-rich protein gp-340 with differential bacterial aggregation. Glycoconjugate Journal. 24: 131-42. PMID 17243023 DOI: 10.1007/s10719-006-9020-1  0.96
2006 Zhuang T, Leffler H, Prestegard JH. Enhancement of bound-state residual dipolar couplings: conformational analysis of lactose bound to Galectin-3. Protein Science : a Publication of the Protein Society. 15: 1780-90. PMID 16751604 DOI: 10.1110/ps.051994306  0.96
2006 Tejler J, Tullberg E, Frejd T, Leffler H, Nilsson UJ. Synthesis of multivalent lactose derivatives by 1,3-dipolar cycloadditions: selective galectin-1 inhibition. Carbohydrate Research. 341: 1353-62. PMID 16697988 DOI: 10.1016/j.carres.2006.04.028  0.96
2006 Aplander K, Tejler J, Toftered J, Carlsson S, Kahl-Knutsson B, Sundin A, Leffler H, Nilsson UJ. Synthesis of a 3'-naphthamido-LacNAc fluorescein conjugate with high selectivity and affinity for galectin-3. Carbohydrate Research. 341: 1363-9. PMID 16697983 DOI: 10.1016/j.carres.2006.04.027  0.96
2006 Patnaik SK, Potvin B, Carlsson S, Sturm D, Leffler H, Stanley P. Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells. Glycobiology. 16: 305-17. PMID 16319083 DOI: 10.1093/glycob/cwj063  0.96
2006 Salameh BA, Sundin A, Leffler H, Nilsson UJ. Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors. Bioorganic & Medicinal Chemistry. 14: 1215-20. PMID 16242339 DOI: 10.1016/j.bmc.2005.09.050  0.96
2006 Bergh A, Leffler H, Sundin A, Nilsson UJ, Kann N. Cobalt-mediated solid phase synthesis of 3-O-alkynylbenzyl galactosides and their evaluation as galectin inhibitors Tetrahedron. 62: 8309-8317. DOI: 10.1016/j.tet.2006.06.057  0.96
2005 Cumpstey I, Sundin A, Leffler H, Nilsson UJ. C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions. Angewandte Chemie (International Ed. in English). 44: 5110-2. PMID 16007713 DOI: 10.1002/anie.200500627  0.96
2005 Salameh BA, Leffler H, Nilsson UJ. 3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3. Bioorganic & Medicinal Chemistry Letters. 15: 3344-6. PMID 15963723 DOI: 10.1016/j.bmcl.2005.05.084  0.96
2005 Cumpstey I, Carlsson S, Leffler H, Nilsson UJ. Synthesis of a phenyl thio-beta-D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7. Organic & Biomolecular Chemistry. 3: 1922-32. PMID 15889175 DOI: 10.1039/b502354h  0.96
2005 Tejler J, Leffler H, Nilsson UJ. Synthesis of O-galactosyl aldoximes as potent LacNAc-mimetic galectin-3 inhibitors. Bioorganic & Medicinal Chemistry Letters. 15: 2343-5. PMID 15837322 DOI: 10.1016/j.bmcl.2005.02.079  0.96
2005 Sabirsh A, Wetterholm A, Bristulf J, Leffler H, Haeggström JZ, Owman C. Fluorescent leukotriene B4: potential applications. Journal of Lipid Research. 46: 1339-46. PMID 15805550 DOI: 10.1194/jlr.D500005-JLR200  0.96
2005 Sörme P, Arnoux P, Kahl-Knutsson B, Leffler H, Rini JM, Nilsson UJ. Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction. Journal of the American Chemical Society. 127: 1737-43. PMID 15701008 DOI: 10.1021/ja043475p  0.96
2004 Sörme P, Kahl-Knutsson B, Huflejt M, Nilsson UJ, Leffler H. Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions. Analytical Biochemistry. 334: 36-47. PMID 15464951 DOI: 10.1016/j.ab.2004.06.042  0.96
2004 Almkvist J, Dahlgren C, Leffler H, Karlsson A. Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe. Experimental Cell Research. 298: 74-82. PMID 15242763 DOI: 10.1016/j.yexcr.2004.04.006  0.96
2004 Huflejt ME, Leffler H. Galectin-4 in normal tissues and cancer. Glycoconjugate Journal. 20: 247-55. PMID 15115909 DOI: 10.1023/B:GLYC.0000025819.54723.a0  0.96
2004 Houzelstein D, Gonçalves IR, Fadden AJ, Sidhu SS, Cooper DN, Drickamer K, Leffler H, Poirier F. Phylogenetic analysis of the vertebrate galectin family. Molecular Biology and Evolution. 21: 1177-87. PMID 14963092 DOI: 10.1093/molbev/msh082  0.96
2004 Leffler H, Carlsson S, Hedlund M, Qian Y, Poirier F. Introduction to galectins. Glycoconjugate Journal. 19: 433-40. PMID 14758066 DOI: 10.1023/B:GLYC.0000014072.34840.04  0.96
2003 Oberg CT, Carlsson S, Fillion E, Leffler H, Nilsson UJ. Efficient and expedient two-step pyranose-retaining fluorescein conjugation of complex reducing oligosaccharides: galectin oligosaccharide specificity studies in a fluorescence polarization assay. Bioconjugate Chemistry. 14: 1289-97. PMID 14624646 DOI: 10.1021/bc034130j  0.96
2003 Sörme P, Kahl-Knutsson B, Wellmar U, Magnusson BG, Leffler H, Nilsson UJ. Design and synthesis of galectin inhibitors. Methods in Enzymology. 363: 157-69. PMID 14579574 DOI: 10.1016/S0076-6879(03)01050-4  0.96
2003 Sörme P, Kahl-Knutson B, Wellmar U, Nilsson UJ, Leffler H. Fluorescence polarization to study galectin-ligand interactions. Methods in Enzymology. 362: 504-12. PMID 12968384 DOI: 10.1016/S0076-6879(03)01033-4  0.96
2003 John CM, Leffler H, Kahl-Knutsson B, Svensson I, Jarvis GA. Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2374-83. PMID 12796408  0.96
2003 Umemoto K, Leffler H, Venot A, Valafar H, Prestegard JH. Conformational differences in liganded and unliganded states of Galectin-3. Biochemistry. 42: 3688-95. PMID 12667058 DOI: 10.1021/bi026671m  0.96
2002 Sjöber K, Eriksson S, Tenngart B, Roth EB, Leffler H, Stenberg P. Factor XIII and tissue transglutaminase antibodies in coeliac and inflammatory bowel disease. Autoimmunity. 35: 357-64. PMID 12515290 DOI: 10.1080/0891693021000005402  0.96
2002 John CM, Jarvis GA, Swanson KV, Leffler H, Cooper MD, Huflejt ME, Griffiss JM. Galectin-3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected. Cellular Microbiology. 4: 649-62. PMID 12366402 DOI: 10.1046/j.1462-5822.2002.00219.x  0.96
2002 Almkvist J, Dahlgren C, Leffler H, Karlsson A. Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1. Journal of Immunology (Baltimore, Md. : 1950). 168: 4034-41. PMID 11937561  0.96
2002 Sörme P, Qian Y, Nyholm PG, Leffler H, Nilsson UJ. Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine. Chembiochem : a European Journal of Chemical Biology. 3: 183-9. PMID 11921396 DOI: 10.1002/1439-7633(20020301)3:2/3<183::AID-CBIC183>3.0.CO;2-#  0.96
2002 Thomsson KA, Prakobphol A, Leffler H, Reddy MS, Levine MJ, Fisher SJ, Hansson GC. The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and diverse. Glycobiology. 12: 1-14. PMID 11825880  0.96
2001 Jain NU, Venot A, Umemoto K, Leffler H, Prestegard JH. Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands. Protein Science : a Publication of the Protein Society. 10: 2393-400. PMID 11604544 DOI: 10.1110/ps.17401  0.96
2001 Capon C, Maes E, Michalski JC, Leffler H, Kim YS. Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon. The Biochemical Journal. 358: 657-64. PMID 11577689  0.96
2001 Umemoto K, Leffler H. Assignment of 1H, 15N and 13C resonances of the carbohydrate recognition domain of human galectin-3. Journal of Biomolecular Nmr. 20: 91-2. PMID 11430761 DOI: 10.1023/A:1011269008175  0.96
2001 Medzihradszky KF, Leffler H, Baldwin MA, Burlingame AL. Protein identification by in-gel digestion, high-performance liquid chromatography, and mass spectrometry: peptide analysis by complementary ionization techniques. Journal of the American Society For Mass Spectrometry. 12: 215-21. PMID 11212006 DOI: 10.1016/S1044-0305(00)00214-2  0.96
2001 Leffler H. Galectins structure and function--a synopsis. Results and Problems in Cell Differentiation. 33: 57-83. PMID 11190679  0.96
2001 Almkvist J, Fäldt J, Dahlgren C, Leffler H, Karlsson A. Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe. Infection and Immunity. 69: 832-7. PMID 11159975 DOI: 10.1128/IAI.69.2.832-837.2001  0.96
2000 Prakobphol A, Xu F, Hoang VM, Larsson T, Bergstrom J, Johansson I, Frängsmyr L, Holmskov U, Leffler H, Nilsson C, Borén T, Wright JR, Strömberg N, Fisher SJ. Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340. The Journal of Biological Chemistry. 275: 39860-6. PMID 11007786 DOI: 10.1074/jbc.M006928200  0.96
1999 Feuk-Lagerstedt E, Jordan ET, Leffler H, Dahlgren C, Karlsson A. Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 163: 5592-8. PMID 10553088  0.96
1999 Prakobphol A, Tangemann K, Rosen SD, Hoover CI, Leffler H, Fisher SJ. Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria. Biochemistry. 38: 6817-25. PMID 10346903 DOI: 10.1021/bi990145m  0.96
1999 Hang L, Haraoka M, Agace WW, Leffler H, Burdick M, Strieter R, Svanborg C. Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. Journal of Immunology (Baltimore, Md. : 1950). 162: 3037-44. PMID 10072556  0.96
1999 Svensson M, Sabharwal H, Håkansson A, Mossberg AK, Lipniunas P, Leffler H, Svanborg C, Linse S. Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells. The Journal of Biological Chemistry. 274: 6388-96. PMID 10037730 DOI: 10.1074/jbc.274.10.6388  0.96
1998 Seetharaman J, Kanigsberg A, Slaaby R, Leffler H, Barondes SH, Rini JM. X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. The Journal of Biological Chemistry. 273: 13047-52. PMID 9582341 DOI: 10.1074/jbc.273.21.13047  0.96
1998 Karlsson A, Follin P, Leffler H, Dahlgren C. Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils. Blood. 91: 3430-8. PMID 9558402  0.96
1998 Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ. Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. Biochemistry. 37: 4916-27. PMID 9538010 DOI: 10.1021/bi972612a  0.96
1998 Gitt MA, Xia YR, Atchison RE, Lusis AJ, Barondes SH, Leffler H. Sequence, structure, and chromosomal mapping of the mouse Lgals6 gene, encoding galectin-6. The Journal of Biological Chemistry. 273: 2961-70. PMID 9446609 DOI: 10.1074/jbc.273.5.2961  0.96
1998 Gitt MA, Colnot C, Poirier F, Nani KJ, Barondes SH, Leffler H. Galectin-4 and galectin-6 are two closely related lectins expressed in mouse gastrointestinal tract. The Journal of Biological Chemistry. 273: 2954-60. PMID 9446608 DOI: 10.1074/jbc.273.5.2954  0.96
1997 Capon C, Wieruszeski JM, Lemoine J, Byrd JC, Leffler H, Kim YS. Sulfated lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin. The Journal of Biological Chemistry. 272: 31957-68. PMID 9405387 DOI: 10.1074/jbc.272.51.31957  0.96
1997 Prakobphol A, Leffler H, Hoover CI, Fisher SJ. Palmitoyl carnitine, a lysophospholipase-transacylase inhibitor, prevents Candida adherence in vitro. Fems Microbiology Letters. 151: 89-94. PMID 9198287 DOI: 10.1016/S0378-1097(97)00146-8  0.96
1997 Huflejt ME, Jordan ET, Gitt MA, Barondes SH, Leffler H. Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion. The Journal of Biological Chemistry. 272: 14294-303. PMID 9162064 DOI: 10.1074/jbc.272.22.14294  0.96
1997 Gitt MA, Jordan ET, Leffler H. Galectin-2, galectins-5 and -9, and galectins-4 and -6 Trends in Glycoscience and Glycotechnology. 9: 87-93.  0.96
1996 Mey A, Leffler H, Hmama Z, Normier G, Revillard JP. The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites. Journal of Immunology (Baltimore, Md. : 1950). 156: 1572-7. PMID 8568262  0.96
1995 Leonidas DD, Elbert BL, Zhou Z, Leffler H, Ackerman SJ, Acharya KR. Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure (London, England : 1993). 3: 1379-93. PMID 8747464 DOI: 10.1016/S0969-2126(01)00275-1  0.96
1995 Gitt MA, Wiser MF, Leffler H, Herrmann J, Xia YR, Massa SM, Cooper DN, Lusis AJ, Barondes SH. Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes. The Journal of Biological Chemistry. 270: 5032-8. PMID 7890611 DOI: 10.1074/jbc.270.10.5032  0.96
1995 Hemmerich S, Leffler H, Rosen SD. Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin. The Journal of Biological Chemistry. 270: 12035-47. PMID 7538131  0.96
1995 Leffler H, Agace W, Hedges S, Lindstedt R, Svensson M, Svanborg C. Strategies for studying bacterial adhesion in vivo Methods in Enzymology. 253: 206-220. PMID 7476387 DOI: 10.1016/S0076-6879(95)53020-7  0.96
1995 Prakobphol A, Leffler H, Fisher SJ. Identifying bacterial receptor proteins and quantifying strength of interactions they mediate Methods in Enzymology. 253: 132-142. PMID 7476382 DOI: 10.1016/S0076-6879(95)53014-2  0.96
1994 Barondes SH, Castronovo V, Cooper DN, Cummings RD, Drickamer K, Feizi T, Gitt MA, Hirabayashi J, Hughes C, Kasai K. Galectins: a family of animal beta-galactoside-binding lectins. Cell. 76: 597-8. PMID 8124704 DOI: 10.1016/0092-8674(94)90498-7  0.96
1994 Prakobphol A, Leffler H, Fisher SJ. Specific adherence of Candida tropicalis to lysophospholipids Biochemistry. 33: 9496-9503. PMID 8068624  0.96
1994 Barondes SH, Cooper DN, Gitt MA, Leffler H. Galectins. Structure and function of a large family of animal lectins. The Journal of Biological Chemistry. 269: 20807-10. PMID 8063692  0.96
1994 Mandrell RE, Apicella MA, Lindstedt R, Leffler H. Possible interaction between animal lectins and bacterial carbohydrates Methods in Enzymology. 236: 231-254. PMID 7968613 DOI: 10.1016/0076-6879(94)36019-7  0.96
1993 Lindstedt R, Apodaca G, Barondes SH, Mostov KE, Leffler H. Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. The Journal of Biological Chemistry. 268: 11750-7. PMID 8505302  0.96
1993 Oda Y, Herrmann J, Gitt MA, Turck CW, Burlingame AL, Barondes SH, Leffler H. Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain. The Journal of Biological Chemistry. 268: 5929-39. PMID 8449956  0.96
1993 Mehrabian M, Gitt MA, Sparkes RS, Leffler H, Barondes SH, Lusis AJ. Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. Genomics. 15: 418-20. PMID 8449510 DOI: 10.1006/geno.1993.1078  0.96
1993 Massa SM, Cooper DN, Leffler H, Barondes SH. L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity. Biochemistry. 32: 260-7. PMID 8418845 DOI: 10.1021/bi00052a033  0.96
1993 Lobsanov YD, Gitt MA, Leffler H, Barondes S, Rini JM. Crystallization and preliminary X-ray diffraction analysis of the human dimeric S-Lac lectin (L-14-II). Journal of Molecular Biology. 233: 553-5. PMID 8411163 DOI: 10.1006/jmbi.1993.1533  0.96
1993 Lobsanov YD, Gitt MA, Leffler H, Barondes SH, Rini JM. X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution. The Journal of Biological Chemistry. 268: 27034-8. PMID 8262940  0.96
1993 Huflejt ME, Turck CW, Lindstedt R, Barondes SH, Leffler H. L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I. The Journal of Biological Chemistry. 268: 26712-8. PMID 8253806  0.96
1993 Herrmann J, Turck CW, Atchison RE, Huflejt ME, Poulter L, Gitt MA, Burlingame AL, Barondes SH, Leffler H. Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase. The Journal of Biological Chemistry. 268: 26704-11. PMID 8253805  0.96
1993 Prakobphol A, Leffler H, Fisher SJ. The high-molecular-weight human mucin is the primary salivary carrier of ABH, Lea, Leb blood group antigens Critical Reviews in Oral Biology and Medicine. 4: 325-333. PMID 7690601  0.96
1992 Marschal P, Herrmann J, Leffler H, Barondes SH, Cooper DN. Sequence and specificity of a soluble lactose-binding lectin from Xenopus laevis skin. The Journal of Biological Chemistry. 267: 12942-9. PMID 1618791  0.96
1992 Lomberg H, Jodal U, Leffler H, Man PD, Svanborg C. Blood group non-secretors have an increased inflammatory response to urinary tract infection Scandinavian Journal of Infectious Diseases. 24: 77-83. PMID 1589729 DOI: 10.3109/00365549209048404  0.96
1992 Gitt MA, Massa SM, Leffler H, Barondes SH. Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin. The Journal of Biological Chemistry. 267: 10601-6. PMID 1375225  0.96
1991 Oda Y, Leffler H, Sakakura Y, Kasai K, Barondes SH. Human breast carcinoma cDNA encoding a galactoside-binding lectin homologous to mouse Mac-2 antigen. Gene. 99: 279-83. PMID 2022338 DOI: 10.1016/0378-1119(91)90139-3  0.96
1991 Gillece-Castro BL, Prakobphol A, Burlingame AL, Leffler H, Fisher SJ. Structure and bacterial receptor activity of a human salivary proline-rich glycoprotein Journal of Biological Chemistry. 266: 17358-17368. PMID 1894623  0.96
1991 Rafiee P, Leffler H, Byrd JC, Cassels FJ, Boedeker EC, Kim YS. A sialoglycoprotein complex linked to the microvillus cytoskeleton acts as a receptor for pilus (AF/R1) mediated adhesion of enteropathogenic Escherichia coli (RDEC-1) in rabbit small intestine Journal of Cell Biology. 115: 1021-1029. PMID 1683351  0.96
1991 Lindstedt R, Larson G, Falk P, Jodal U, Leffler H, Svanborg C. The receptor repertoir defines the host range for attaching Escherichia coli strains that recognize globo-A Infection and Immunity. 59: 1086-1092. PMID 1671774  0.96
1990 Svanborg Eden C, Andersson B, Aniansson G, Lindstedt R, De Man P, Nielsen A, Leffler H, Wold A. Inhibition of bacterial attachment: Examples from the urinary and respiratory tracts Current Topics in Microbiology and Immunology. 151: 167-184. PMID 2196162  0.96
1990 Leffler H, Svanborg-Eden C. Host epithelial glycoconjugates and pathogenic bacteria American Journal of Respiratory Cell and Molecular Biology. 2: 409-411. PMID 2187491  0.96
1990 Baker N, Hansson GC, Leffler H, Riise G, Svanborg-Eden C. Glycosphingolipid receptors for Pseudomonas aeruginosa Infection and Immunity. 58: 2361-2366. PMID 2114364  0.96
1989 Leffler H, Masiarz FR, Barondes SH. Soluble lactose-binding vertebrate lectins: a growing family. Biochemistry. 28: 9222-9. PMID 2605254  0.96
1989 Tomisawa S, Kogure T, Kuroume T, Leffler H, Lomberg H, Shimabukoro N, Terao K, Edén CS. P blood group and proneness to urinary tract infection in japanese children Scandinavian Journal of Infectious Diseases. 21: 403-408. PMID 2587941 DOI: 10.3109/00365548909167444  0.96
1989 Lindstedt R, Baker N, Falk P, Hull R, Hull S, Karr J, Leffler H, Svanborg Edén C, Larson G. Binding specificities of wild-type and cloned Escherichia coli strains that recognize globo-A. Infection and Immunity. 57: 3389-94. PMID 2572551  0.96
1989 Finne J, Breimer ME, Hansson GC, Karlsson KA, Leffler H, Vliegenthart JF, van Halbeek H. Novel polyfucosylated N-linked glycopeptides with blood group A, H, X, and Y determinants from human small intestinal epithelial cells. The Journal of Biological Chemistry. 264: 5720-35. PMID 2466830  0.96
1988 Leffler H. The role of epithelial cell surface glycoconjugates in self-not-self and self-self interaction Monographs in Allergy. 24: 25-34. PMID 3362143  0.96
1988 Barondes SH, Gitt MA, Leffler H, Cooper DN. Multiple soluble vertebrate galactoside-binding lectins. Biochimie. 70: 1627-32. PMID 3149527 DOI: 10.1016/0300-9084(88)90298-2  0.96
1987 Barondes SH, Leffler H. Soluble lactose-binding lectins from chicken and rat. Methods in Enzymology. 138: 510-5. PMID 3600343  0.96
1987 Björk S, Breimer ME, Hansson GC, Karlsson KA, Leffler H. Structures of blood group glycosphingolipids of human small intestine. A relation between the expression of fucolipids of epithelial cells and the ABO, Le and Se phenotype of the donor Journal of Biological Chemistry. 262: 6758-6765. PMID 3571286  0.96
1987 Larson G, Watsfeldt P, Falk P, Leffler H, Koprowski H. Fecal excretion of intestinal glycosphingolipids by newborns and young children Febs Letters. 214: 41-44. PMID 3569516 DOI: 10.1016/0014-5793(87)80009-1  0.96
1987 Svanborg Eden C, Andersson B, Aniansson G, Leffler H, Lomberg H, Mestecky J, Wold AE. Glycoconjugate receptors for bacteria attaching to mucosal sites: examples for Escherichia coli and Streptococcus pneumoniae Advances in Experimental Medicine and Biology. 216: 931-939. PMID 2892361  0.96
1987 Enerback S, Larsson AC, Leffler H, Lundell A, de Man P, Nilsson B, Svanborg-Edén C. Binding to galactoseα1→4galactoseβ-containing receptors as potential diagnostic tool in urinary tract infection Journal of Clinical Microbiology. 25: 407-411. PMID 2880868  0.96
1987 de Man P, Cedergren B, Enerback S, Larsson AC, Leffler H, Lundell AL, Nilsson B, Svanborg-Edén C. Receptor-specific agglutination tests for detection of bacteria that bind globoseries glycolipids Journal of Clinical Microbiology. 25: 401-406. PMID 2880867  0.96
1987 Sparrow CP, Leffler H, Barondes SH. Multiple soluble beta-galactoside-binding lectins from human lung. The Journal of Biological Chemistry. 262: 7383-90. PMID 2438278  0.96
1986 Leffler H, Hansson GC, Stromberg N. A novel sulfoglycosphingolipid of mouse small intestine, IV3-sulfogangliotetraosylceramide, demonstrated by negative ion fast atom bombardment mass spectrometry Journal of Biological Chemistry. 261: 1440-1444. PMID 3944094  0.96
1986 Leffler H, Barondes SH. Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides. The Journal of Biological Chemistry. 261: 10119-26. PMID 3733704  0.96
1986 Lomberg H, Cedergren B, Leffler H, Nilsson B, Carlström AS, Svanborg-Edén C. Influence of blood group on the availability of receptors for attachment of uropathogenic Escherichia coli Infection and Immunity. 51: 919-926. PMID 2868993  0.96
1985 Breimer ME, Hansson GC, Leffler H. The specific glycosphingolipid composition of human ureteral epithelial cells Journal of Biochemistry. 98: 1169-1180. PMID 4086474  0.96
1985 Hagberg L, Edén CS, Leffler H. Non-antibiotic prevention of urinary tract infection Infection. 13: S196-S201. PMID 3902654 DOI: 10.1007/BF01644430  0.96
1985 Bock K, Breimer ME, Brignole A, Hansson GC, Karlsson KA, Larson G, Leffler H, Samuelsson BE, Strömberg N, Edén CS. Specificity of binding of a strain of uropathogenic Escherichia coli to Galα1→4Gal-containing glycosphingolipids Journal of Biological Chemistry. 260: 8545-8551. PMID 3891756  0.96
1984 Andersson B, Fogh A, Jørgensen F, Larsson S, Leffler H, Magnusson G, Nylén O, Südow C, Svanborg Edén C. Attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells in vitro - mechanism of binding Otolaryngology - Head and Neck Surgery. 92: 266-269. PMID 6431363  0.96
1984 Svanborg Edén C, Andersson B, Leffler H, Magnusson G. Glycoconjugate receptors involved in the adhesion of Escherichia coli and Streptococcus pneumoniae to epithelial cells Journal of Dental Research. 63: 386-388. PMID 6365999  0.96
1983 Andersson B, Dahmen J, Frejd T, Leffler H, Magnusson G, Noori G, Edén CS. Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells Journal of Experimental Medicine. 158: 559-567. PMID 6886624  0.96
1983 Breimer M, Hansson GC, Karlsson KA, Leffler H. The preparative separation of sialic acid-containing lipids from sulphate group-containing glycolipids from small intestine of different animals. Analysis by thin-layer chromatography and detection of novel species Journal of Biochemistry. 93: 1473-1485. PMID 6885733  0.96
1983 Andersson B, Leffler H, Magnusson G, Svanborg Eden C. Molecular mechanisms of adhesion of Streptococcus Pneumoniae to human oropharyngeal epithelial cells Scandinavian Journal of Infectious Diseases. 15: 45-47. PMID 6580732  0.96
1983 Lomberg H, Hanson LA, Jacobsson B, Jodal U, Leffler H, Edén CS. Correlation of P blood group, vesicoureteral reflux, and bacterial attachment in patients with recurrent pyelonephritis New England Journal of Medicine. 308: 1189-1192. PMID 6341837  0.96
1983 Svanborg Edén C, Hagberg L, Hanson LA, Hull S, Hull R, Jodal U, Leffler H, Lomberg H, Straube E. Bacterial adherence--a pathogenetic mechanism in urinary tract infections caused by Escherichia coli Progress in Allergy. 33: 175-188. PMID 6338511  0.96
1983 Svanborg Edén C, Hull R, Falkow S, Leffler H. Target cell specificity of wild-type E. coli and mutants and clones with genetically defined adhesins. Progress in Food & Nutrition Science. 7: 75-89. PMID 6140705  0.96
1983 Svanborg Edén C, Gotschlich EC, Korhonen TK, Leffler H, Schoolnik G. Aspects on structure and function of pili on uropathogenic Escherichia coli Progress in Allergy. 33: 189-202. PMID 6131425  0.96
1983 Breimer ME, Hansson GC, Karlsson KA, Larson G, Leffler H, Pimlott W, Samuelsson BE, Strömberg N, Teneberg S, Thurin J. Sequencing of large oligosaccharides by direct inlet mass spectrometry. Application to cell surface glycolipids International Journal of Mass Spectrometry and Ion Physics. 48: 113-116. DOI: 10.1016/0020-7381(83)87041-7  0.96
1982 Hansson GC, Karlsson KA, Leffler H, Strömberg N. Gangliotetraosylceramide is a major glycolipid of epithelial cells of mouse small intestine Febs Letters. 139: 291-294. PMID 7075779 DOI: 10.1016/0014-5793(82)80873-9  0.96
1982 Breimer ME, Hansson GC, Karlsson KA, Leffler H. Studies on differentiating epithelial cells of rat small intestine. Alterations in the lipophilic part of glycosphingolipids during cell migration from crypt to villus tip Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 710: 415-427. PMID 7074122 DOI: 10.1016/0005-2760(82)90125-4  0.96
1982 Ångström J, Breimer ME, Falk KE, Hansson GC, Karlsson KA, Leffler H, Pascher I. Structural characterization of glycolipids of rat small intestine having one to eight hexoses in a linear sequence Archives of Biochemistry and Biophysics. 213: 708-725. PMID 7073294 DOI: 10.1016/0003-9861(82)90601-4  0.96
1982 Angström J, Breimer ME, Falk KE, Hansson GC, Karlsson KA, Leffler H. Chemical characterization of penta-, hexa-, hepta-, octa-, and nonaglycosylceramides of rat small intestine having a globoside-like terminus Journal of Biological Chemistry. 257: 682-688. PMID 7054174  0.96
1982 Breimer ME, Hansson GC, Karlsson KA, Leffler H. Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine Journal of Biological Chemistry. 257: 557-568. PMID 7053385  0.96
1982 Eden CS, Freter R, Hagberg L, Hull R, Hull S, Leffler H, Schoolnik G. Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue Nature. 298: 560-562. PMID 7048106 DOI: 10.1038/298560a0  0.96
1982 Breimer ME, Hansson GC, Karlsson KA, Leffler H. Isolation and partial characterization of blood group A and H active glycosphingolipids of rat small intestine Journal of Biological Chemistry. 257: 906-912. PMID 6798034  0.96
1982 Lomberg H, Larsson P, Leffler H, Svanborg-Eden C. Different binding specificities of P. mirabilis compared to E. coli Scandinavian Journal of Infectious Diseases. 14: 37-42. PMID 6753134  0.96
1982 Edén CS, Hagberg L, Lomberg H, Leffler H. Recent progress in the understanding of the role of bacterial adhesion in the pathogenesis of urinary tract infection Infection. 10: 327-332. PMID 6129198 DOI: 10.1007/BF01640890  0.96
1982 Leffler H, Lomberg H, Gotschlich E. Chemical and clinical studies on the interaction of Escherichia coli with host glycolipid receptors in urinary tract infection Scandinavian Journal of Infectious Diseases. 14: 46-51. PMID 6127802  0.96
1981 Angstrom J, Breimer ME, Falk KE, Griph I, Hansson GC, Karlsson KA, Leffler H. Separation and characterization of hematosides with different sialic acids and ceramides from rat small intestine. Different composition of epithelial cells versus non-epithelial tissue and of duodenum versus jejunum-ileum Journal of Biochemistry. 90: 909-921. PMID 7309719  0.96
1981 Lomberg H, Jodal U, Svanborg Edén C, Leffler H, Samuelsson B. P1 BLOOD GROUP AND URINARY TRACT INFECTION The Lancet. 317: 551-552. PMID 6111646 DOI: 10.1016/S0140-6736(81)92878-6  0.96
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