Ioanna Ntai, Ph.D. - Publications

Affiliations: 
2003-2008 Vanderbilt University, Nashville, TN 
 2010- Northwestern University, Evanston, IL 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ntai I, Fornelli L, DeHart CJ, Hutton JE, Doubleday PF, LeDuc RD, van Nispen AJ, Fellers RT, Whiteley G, Boja ES, Rodriguez H, Kelleher NL. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610327 DOI: 10.1073/pnas.1716122115  1
2017 Haverland NA, Waas M, Ntai I, Keppel T, Gundry RL, Kelleher NL. Cell Surface Proteomics of N-Linked Glycoproteins for Typing of Human Lymphocytes. Proteomics. PMID 28834292 DOI: 10.1002/pmic.201700156  1
2016 Gan R, Perez JG, Carlson ED, Ntai I, Isaacs FJ, Kelleher NL, Jewett MC. Translation system engineering in Escherichia coli enhances non-canonical amino acid incorporation into proteins. Biotechnology and Bioengineering. PMID 27987323 DOI: 10.1002/bit.26239  1
2016 Ntai I, Toby TK, LeDuc RD, Kelleher NL. A Method for Label-Free, Differential Top-Down Proteomics. Methods in Molecular Biology (Clifton, N.J.). 1410: 121-33. PMID 26867742 DOI: 10.1007/978-1-4939-3524-6_8  0.64
2015 Amiram M, Haimovich AD, Fan C, Wang YS, Aerni HR, Ntai I, Moonan DW, Ma NJ, Rovner AJ, Hong SH, Kelleher NL, Goodman AL, Jewett MC, Söll D, Rinehart J, et al. Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nature Biotechnology. PMID 26571098 DOI: 10.1038/nbt.3372  1
2015 Ntai I, LeDuc RD, Fellers RT, Erdmann-Gilmore P, Davies SR, Rumsey J, Early BP, Thomas PM, Li S, Compton PD, Ellis MJ, Ruggles KV, Fenyo D, Boja ES, Rodriguez H, et al. Integrated Bottom-up and Top-down Proteomics of Patient-derived Breast Tumor Xenografts. Molecular & Cellular Proteomics : McP. PMID 26503891 DOI: 10.1074/mcp.M114.047480  0.64
2015 Rodrigues Lorenzatto K, Kim K, Ntai I, Prado Paludo G, Camargo de Lima J, Thomas PM, Kelleher NL, Ferreira HB. Top down proteomics reveals mature proteoforms expressed in subcellular fractions of the Echinococcus granulosus pre-adult stage. Journal of Proteome Research. PMID 26465659 DOI: 10.1021/acs.jproteome.5b00642  1
2015 Moatsou D, Li J, Ranji A, Pitto-Barry A, Ntai I, Jewett MC, O'Reilly RK. Self-Assembly of Temperature-Responsive Protein-Polymer Bioconjugates. Bioconjugate Chemistry. PMID 26083370 DOI: 10.1021/acs.bioconjchem.5b00264  1
2015 Hong SH, Kwon YC, Martin RW, Des Soye BJ, de Paz AM, Swonger KN, Ntai I, Kelleher NL, Jewett MC. Improving cell-free protein synthesis through genome engineering of Escherichia coli lacking release factor 1. Chembiochem : a European Journal of Chemical Biology. 16: 844-53. PMID 25737329 DOI: 10.1002/cbic.201402708  1
2014 Kelleher NL, Thomas PM, Ntai I, Compton PD, LeDuc RD. Deep and quantitative top-down proteomics in clinical and translational research. Expert Review of Proteomics. 11: 649-51. PMID 25347991 DOI: 10.1586/14789450.2014.976559  1
2014 Ntai I, Kim K, Fellers RT, Skinner OS, Smith AD, Early BP, Savaryn JP, LeDuc RD, Thomas PM, Kelleher NL. Applying label-free quantitation to top down proteomics. Analytical Chemistry. 86: 4961-8. PMID 24807621 DOI: 10.1021/ac500395k  1
2014 Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, et al. The first pilot project of the consortium for top-down proteomics: a status report. Proteomics. 14: 1130-40. PMID 24644084 DOI: 10.1002/pmic.201300438  1
2014 Li Y, Compton PD, Tran JC, Ntai I, Kelleher NL. Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins. Proteomics. 14: 1158-64. PMID 24596178 DOI: 10.1002/pmic.201300381  1
2014 Durbin KR, Fellers RT, Ntai I, Kelleher NL, Compton PD. Autopilot: an online data acquisition control system for the enhanced high-throughput characterization of intact proteins. Analytical Chemistry. 86: 1485-92. PMID 24400813 DOI: 10.1021/ac402904h  1
2014 Hong SH, Ntai I, Haimovich AD, Kelleher NL, Isaacs FJ, Jewett MC. Cell-free protein synthesis from a release factor 1 deficient Escherichia coli activates efficient and multiple site-specific nonstandard amino acid incorporation. Acs Synthetic Biology. 3: 398-409. PMID 24328168 DOI: 10.1021/sb400140t  1
2013 Rothmann M, Kang M, Villa R, Ntai I, La Clair JJ, Kelleher NL, Chapman E, Burkart MD. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. 135: 5962-5. PMID 23550886 DOI: 10.1021/ja400795m  1
2013 Chen Y, Unger M, Ntai I, McClure RA, Albright JC, Thomson RJ, Kelleher NL. Gobichelin A and B: Mixed-Ligand Siderophores Discovered Using Proteomics. Medchemcomm. 4: 233-238. PMID 23336063 DOI: 10.1039/C2MD20232H  1
2012 Park S, Ntai I, Thomas P, Konishcheva E, Kelleher NL, Statsuk AV. Mechanism-based small molecule cross-linkers of HECT E3 ubiquitin ligase-substrate pairs. Biochemistry. 51: 8327-9. PMID 23043241 DOI: 10.1021/bi301231h  1
2012 Chen Y, Ntai I, Ju KS, Unger M, Zamdborg L, Robinson SJ, Doroghazi JR, Labeda DP, Metcalf WW, Kelleher NL. A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria. Journal of Proteome Research. 11: 85-94. PMID 21978092 DOI: 10.1021/pr2009115  1
2011 Zhang W, Ntai I, Kelleher NL, Walsh CT. tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 108: 12249-53. PMID 21746899 DOI: 10.1073/pnas.1109539108  1
2011 Evans BS, Ntai I, Chen Y, Robinson SJ, Kelleher NL. Proteomics-based discovery of koranimine, a cyclic imine natural product. Journal of the American Chemical Society. 133: 7316-9. PMID 21520944 DOI: 10.1021/ja2015795  1
2011 Hollenhorst MA, Ntai I, Badet B, Kelleher NL, Walsh CT. A head-to-head comparison of eneamide and epoxyamide inhibitors of glucosamine-6-phosphate synthase from the dapdiamide biosynthetic pathway. Biochemistry. 50: 3859-61. PMID 21520904 DOI: 10.1021/bi2004735  1
2011 Zhang W, Ntai I, Bolla ML, Malcolmson SJ, Kahne D, Kelleher NL, Walsh CT. Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. Journal of the American Chemical Society. 133: 5240-3. PMID 21417270 DOI: 10.1021/ja2011109  1
2010 Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, Kelleher NL. The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput. Molecular Biosystems. 6: 1532-9. PMID 20711533 DOI: 10.1039/c000896f  1
2010 Akif M, Ntai I, Sturrock ED, Isaac RE, Bachmann BO, Acharya KR. Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochemical and Biophysical Research Communications. 398: 532-6. PMID 20599761 DOI: 10.1016/j.bbrc.2010.06.113  1
2010 Ntai I, Kelleher NL. Approaches for natural product detection and structural elucidation using mass spectrometry with high mass accuracy Methodologies For Metabolomics: Experimental Strategies and Techniques. 174-184. DOI: 10.1017/CBO9780511996634.008  1
2009 Bumpus SB, Evans BS, Thomas PM, Ntai I, Kelleher NL. A proteomics approach to discovering natural products and their biosynthetic pathways. Nature Biotechnology. 27: 951-6. PMID 19767731 DOI: 10.1038/nbt.1565  1
2009 Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AD, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Marshall AG, Kelleher NL. A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome. Journal of the American Society For Mass Spectrometry. 20: 2183-91. PMID 19747844 DOI: 10.1016/j.jasms.2009.08.001  1
2009 Ghidu VP, Ntai I, Wang J, Jacobs AT, Marnett LJ, Bachmann BO, Sulikowski GA. Combined chemical and biosynthetic route to access a new apoptolidin congener. Organic Letters. 11: 3032-4. PMID 19552384 DOI: 10.1021/ol901045v  1
2008 Ntai I, Bachmann BO. Identification of ACE pharmacophore in the phosphonopeptide metabolite K-26. Bioorganic & Medicinal Chemistry Letters. 18: 3068-71. PMID 18096385 DOI: 10.1016/j.bmcl.2007.11.130  1
2007 Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO. Benzodiazepine biosynthesis in Streptomyces refuineus. Chemistry & Biology. 14: 691-701. PMID 17584616 DOI: 10.1016/j.chembiol.2007.05.009  1
2007 Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO. Benzodiazepine Biosynthesis in Streptomyces refuineus (DOI:10.1016/j.chembiol.2007.05.009) Chemistry and Biology. 14: 870. DOI: 10.1016/j.chembiol.2007.07.006  1
2006 Ntai I, Phelan VV, Bachmann BO. Phosphonopeptide K-26 biosynthetic intermediates in Astrosporangium hypotensionis. Chemical Communications (Cambridge, England). 4518-20. PMID 17283804 DOI: 10.1039/b611768f  1
2005 Ntai I, Manier ML, Hachey DL, Bachmann BO. Biosynthetic origins of C-P bond containing tripeptide K-26. Organic Letters. 7: 2763-5. PMID 15957941 DOI: 10.1021/ol051091d  1
2004 Carter EB, Culver SL, Fox PA, Goode RD, Ntai I, Tickell MD, Traylor RK, Hoffman NW, Davis JH. Sweet success: Ionic liquids derived from non-nutritive sweeteners. Chemical Communications (Cambridge, England). 630-1. PMID 15010753 DOI: 10.1039/b313068a  1
2002 Cole AC, Jensen JL, Ntai I, Tran KL, Weaver KJ, Forbes DC, Davis JH. Novel Brønsted acidic ionic liquids and their use as dual solvent-catalysts. Journal of the American Chemical Society. 124: 5962-3. PMID 12022828 DOI: 10.1021/ja026290w  1
2002 Bates ED, Mayton RD, Ntai I, Davis JH. CO(2) capture by a task-specific ionic liquid. Journal of the American Chemical Society. 124: 926-7. PMID 11829599 DOI: 10.1021/ja017593d  1
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