Keith D. Green - Publications

Affiliations: 
Chemistry University of Kentucky, Lexington, KY 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Punetha A, Ngo HX, Holbrook SYL, Green KD, Willby MJ, Bonnett SA, Krieger K, Dennis EK, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from . Acs Chemical Biology. PMID 32421305 DOI: 10.1021/acschembio.0c00184  1
2019 Green KD, Punetha A, Hou C, Garneau-Tsodikova S, Tsodikov OV. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis. Acs Infectious Diseases. PMID 31433614 DOI: 10.1021/acsinfecdis.9b00228  1
2019 Green KD, Fosso MY, Mayhoub AS, Garneau-Tsodikova S. Investigating the promiscuity of the chloramphenicol nitroreductase from Haemophilus influenzae towards the reduction of 4-nitrobenzene derivatives. Bioorganic & Medicinal Chemistry Letters. PMID 30826292 DOI: 10.1016/j.bmcl.2019.02.025  1
2018 Thamban Chandrika N, Dennis EK, Shrestha SK, Ngo HX, Green KD, Kwiatkowski S, Deaciuc AG, Dwoskin LP, Watt DS, Garneau-Tsodikova S. N,N'-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents. European Journal of Medicinal Chemistry. 164: 273-281. PMID 30597328 DOI: 10.1016/j.ejmech.2018.12.042  1
2018 Green KD, Fosso MY, Garneau-Tsodikova S. Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors. Molecules (Basel, Switzerland). 23. PMID 30544832 DOI: 10.3390/molecules23123252  1
2018 Story S, Skriba MJ, Maiti K, Nihar Ranjan, Degtyareva NN, Green KD, Khodaverdian V, Oyelere AK, Garneau-Tsodikova S, Arya DP. Synthesis, antimicrobial activity, attenuation of aminoglycoside resistance in MRSA, and ribosomal A-site binding of pyrene-neomycin conjugates. European Journal of Medicinal Chemistry. 163: 381-393. PMID 30530174 DOI: 10.1016/j.ejmech.2018.11.022  1
2018 Scutigliani EM, Scholl ER, Grootemaat AE, Khanal S, Kochan JA, Krawczyk PM, Reits EA, Garzan A, Ngo HX, Green KD, Garneau-Tsodikova S, Ruijter JM, van Veen HA, van der Wel NN. Interfering With DNA Decondensation as a Strategy Against Mycobacteria. Frontiers in Microbiology. 9: 2034. PMID 30233521 DOI: 10.3389/fmicb.2018.02034  1
2018 Mori S, Green KD, Choi R, Buchko GW, Fried MG, Garneau-Tsodikova S. Using MbtH-like proteins to alter substrate profile of a nonribosomal peptide adenylation enzyme. Chembiochem : a European Journal of Chemical Biology. PMID 30134012 DOI: 10.1002/cbic.201800240  1
2018 Louzoun Zada S, Green KD, Shrestha SK, Herzog IM, Garneau-Tsodikova S, Fridman M. Derivatives of Ribosome-Inhibiting Antibiotic Chloramphenicol Inhibit the Biosynthesis of Bacterial Cell Wall. Acs Infectious Diseases. PMID 29714997 DOI: 10.1021/acsinfecdis.8b00078  1
2018 Fosso MY, Shrestha SK, Thamban Chandrika N, Dennis EK, Green KD, Garneau-Tsodikova S. Differential Effects of Linkers on the Activity of Amphiphilic Tobramycin Antifungals. Molecules (Basel, Switzerland). 23. PMID 29652845 DOI: 10.3390/molecules23040899  1
2018 Ngo HX, Green KD, Gajadeera CS, Willby MJ, Holbrook SYL, Hou C, Garzan A, Mayhoub AS, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29601176 DOI: 10.1021/acsinfecdis.8b00074  1
2018 Green KD, Biswas T, Pang AH, Willby MJ, Reed MS, Stuchlik O, Pohl J, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight. Biochemistry. PMID 29345920 DOI: 10.1021/acs.biochem.7b01089  1
2017 Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Combating Eis-mediated kanamycin resistance of M. tuber-culosis by novel pyrrolo[1,5-a]pyrazine-based Eis inhibitors. Acs Infectious Diseases. PMID 28192916 DOI: 10.1021/acsinfecdis.6b00193  1
2017 Degtyareva NN, Gong C, Story S, Levinson N, Oyelere AK, Green KD, Garneau-Tsodikova S, Arya DP. Antimicrobial Activity, AME Resistance and Translation Inhibition Studies of Anthraquinone-Neomycin Conjugates. Acs Infectious Diseases. PMID 28103015 DOI: 10.1021/acsinfecdis.6b00176  1
2016 Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis. Acs Medicinal Chemistry Letters. 7: 1219-1221. PMID 27994767 DOI: 10.1021/acsmedchemlett.6b00261  1
2016 Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 59: 10619-10628. PMID 27933949 DOI: 10.1021/acs.jmedchem.6b01161  1
2016 Shrestha SK, Kril LM, Green KD, Kwiatkowski S, Sviripa VM, Nickell JR, Dwoskin LP, Watt DS, Garneau-Tsodikova S. Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. Bioorganic & Medicinal Chemistry. PMID 27769670 DOI: 10.1016/j.bmc.2016.10.009  1
2016 Ngo HX, Garneau-Tsodikova S, Green KD. A complex game of hide and seek: the search for new antifungals. Medchemcomm. 7: 1285-1306. PMID 27766140 DOI: 10.1039/C6MD00222F  1
2016 Ngo HX, Shrestha SK, Green KD, Garneau-Tsodikova S. Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. PMID 27073054 DOI: 10.1016/j.bmc.2016.03.060  1
2016 Liu X, Jin Y, Cai W, Green KD, Goswami A, Garneau-Tsodikova S, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW. Organic & Biomolecular Chemistry. PMID 27050157 DOI: 10.1039/c6ob00381h  1
2016 Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Potent inhibitors of acetyltransferase Eis overcome kanamycin re-sistance in Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27010218 DOI: 10.1021/acschembio.6b00110  1
2016 Jin Y, Watkins D, Degtyareva NN, Green KD, Spano MN, Garneau-Tsodikova S, Arya DP. Arginine-linked neomycin B dimers: synthesis, rRNA binding, and resistance enzyme activity. Medchemcomm. 7: 164-169. PMID 26811742 DOI: 10.1039/C5MD00427F  1
2016 Ngo HX, Garneau-Tsodikova S, Green KD. A complex game of hide and seek: The search for new antifungals Medchemcomm. 7: 1285-1306. DOI: 10.1039/c6md00222f  1
2015 Green KD, Pricer RE, Stewart MN, Garneau-Tsodikova S. Comparative Study of Eis-like Enzymes from Pathogenic and Nonpathogenic Bacteria. Acs Infectious Diseases. 1: 272-83. PMID 27622743 DOI: 10.1021/acsinfecdis.5b00036  1
2015 Thamban Chandrika N, Green KD, Houghton JL, Garneau-Tsodikova S. Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides. Acs Medicinal Chemistry Letters. 6: 1134-1139. PMID 26617967 DOI: 10.1021/acsmedchemlett.5b00255  1
2015 Fosso MY, Shrestha SK, Green KD, Garneau-Tsodikova S. Synthesis and bioactivities of kanamycin B-derived cationic amphiphiles. Journal of Medicinal Chemistry. PMID 26592740 DOI: 10.1021/acs.jmedchem.5b01375  1
2015 Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones. Organic & Biomolecular Chemistry. 13: 9418-26. PMID 26248214 DOI: 10.1039/c5ob01478f  1
2015 Wasserman MR, Pulk A, Zhou Z, Altman RB, Zinder JC, Green KD, Garneau-Tsodikova S, Doudna Cate JH, Blanchard SC. Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions. Nature Communications. 6: 7896. PMID 26224058 DOI: 10.1038/ncomms8896  1
2015 Shrestha SK, Fosso MY, Green KD, Garneau-Tsodikova S. Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal Agents. Antimicrobial Agents and Chemotherapy. 59: 4861-9. PMID 26033722 DOI: 10.1128/AAC.00229-15  1
2015 Fosso MY, Zhu H, Green KD, Garneau-Tsodikova S, Fredrick K. Tobramycin Variants with Enhanced Ribosome-Targeting Activity. Chembiochem : a European Journal of Chemical Biology. 16: 1565-70. PMID 26033429 DOI: 10.1002/cbic.201500256  1
2015 Li Y, Green KD, Johnson BR, Garneau-Tsodikova S. Inhibition of Aminoglycoside Acetyltransferase Resistance Enzymes by Metal Salts. Antimicrobial Agents and Chemotherapy. 59: 4148-56. PMID 25941215 DOI: 10.1128/AAC.00885-15  1
2015 Green KD, Biswas T, Chang C, Wu R, Chen W, Janes BK, Chalupska D, Gornicki P, Hanna PC, Tsodikov OV, Joachimiak A, Garneau-Tsodikova S. Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis. Biochemistry. 54: 3197-206. PMID 25928210 DOI: 10.1021/acs.biochem.5b00244  1
2015 Watkins D, Kumar S, Green KD, Arya DP, Garneau-Tsodikova S. Influence of Linker Length and Composition on Enzymatic Activity and Ribosomal Binding of Neomycin Dimers. Antimicrobial Agents and Chemotherapy. 59: 3899-905. PMID 25896697 DOI: 10.1128/AAC.00861-15  1
2015 Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/jbc.M115.646414  1
2015 Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP. Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library. Acs Chemical Biology. 10: 1278-89. PMID 25706406 DOI: 10.1021/cb5010367  1
2015 Gajadeera C, Willby MJ, Green KD, Shaul P, Fridman M, Garneau-Tsodikova S, Posey JE, Tsodikov OV. Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG. The Journal of Antibiotics. 68: 153-7. PMID 25248725 DOI: 10.1038/ja.2014.131  1
2015 Blacher E, Ben Baruch B, Levy A, Geva N, Green KD, Garneau-Tsodikova S, Fridman M, Stein R. Inhibition of glioma progression by a newly discovered CD38 inhibitor. International Journal of Cancer. Journal International Du Cancer. 136: 1422-33. PMID 25053177 DOI: 10.1002/ijc.29095  1
2015 Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones Organic and Biomolecular Chemistry. 13: 9418-9426. DOI: 10.1039/c5ob01478f  1
2014 Tsodikov OV, Green KD, Garneau-Tsodikova S. A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein. Plos One. 9: e92370. PMID 24699000 DOI: 10.1371/journal.pone.0092370  1
2013 Biswas T, Green KD, Garneau-Tsodikova S, Tsodikov OV. Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry. 52: 6905-10. PMID 24004110 DOI: 10.1021/bi4011286  1
2013 Green KD, Garneau-Tsodikova S. Resistance in tuberculosis: what do we know and where can we go? Frontiers in Microbiology. 4: 208. PMID 23888158 DOI: 10.3389/fmicb.2013.00208  1
2013 Jennings BC, Labby KJ, Green KD, Garneau-Tsodikova S. Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis. Biochemistry. 52: 5125-32. PMID 23837529 DOI: 10.1021/bi4002985  1
2013 Berkov-Zrihen Y, Green KD, Labby KJ, Feldman M, Garneau-Tsodikova S, Fridman M. Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. Journal of Medicinal Chemistry. 56: 5613-25. PMID 23786357 DOI: 10.1021/jm400707f  1
2013 Eckroat TJ, Green KD, Reed RA, Bornstein JJ, Garneau-Tsodikova S. Investigation of the role of linker moieties in bifunctional tacrine hybrids. Bioorganic & Medicinal Chemistry. 21: 3614-23. PMID 23535563 DOI: 10.1016/j.bmc.2013.02.047  1
2013 Green KD, Garneau-Tsodikova S. Domain dissection and characterization of the aminoglycoside resistance enzyme ANT(3″)-Ii/AAC(6')-IId from Serratia marcescens. Biochimie. 95: 1319-25. PMID 23485681 DOI: 10.1016/j.biochi.2013.02.011  1
2013 Houghton JL, Green KD, Pricer RE, Mayhoub AS, Garneau-Tsodikova S. Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes. The Journal of Antimicrobial Chemotherapy. 68: 800-5. PMID 23233486 DOI: 10.1093/jac/dks497  1
2013 Kochi A, Eckroat TJ, Green KD, Mayhoub AS, Lim MH, Garneau-Tsodikova S. A novel hybrid of 6-chlorotacrine and metal-amyloid-β modulator for inhibition of acetylcholinesterase and metal-induced amyloid-β aggregation Chemical Science. 4: 4137-4145. DOI: 10.1039/c3sc51902c  1
2012 Senevirathne C, Green KD, Pflum MK. Kinase-Catalyzed Biotinylation. Current Protocols in Chemical Biology. 4: 83-100. PMID 25177527 DOI: 10.1002/9780470559277.ch110228  0.88
2012 Pricer RE, Houghton JL, Green KD, Mayhoub AS, Garneau-Tsodikova S. Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis. Molecular Biosystems. 8: 3305-13. PMID 23090428 DOI: 10.1039/c2mb25341k  1
2012 Chen W, Green KD, Garneau-Tsodikova S. Cosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 56: 5831-8. PMID 22948873 DOI: 10.1128/AAC.00932-12  1
2012 Chen W, Green KD, Tsodikov OV, Garneau-Tsodikova S. Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition. Biochemistry. 51: 4959-67. PMID 22646013 DOI: 10.1021/bi3004473  1
2012 Herzog IM, Green KD, Berkov-Zrihen Y, Feldman M, Vidavski RR, Eldar-Boock A, Satchi-Fainaro R, Eldar A, Garneau-Tsodikova S, Fridman M. 6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes. Angewandte Chemie (International Ed. in English). 51: 5652-6. PMID 22499286 DOI: 10.1002/anie.201200761  1
2012 Green KD, Chen W, Garneau-Tsodikova S. Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis. Chemmedchem. 7: 73-7. PMID 21898832 DOI: 10.1002/cmdc.201100332  1
2011 Green KD, Chen W, Garneau-Tsodikova S. Effects of altering aminoglycoside structures on bacterial resistance enzyme activities. Antimicrobial Agents and Chemotherapy. 55: 3207-13. PMID 21537023 DOI: 10.1128/AAC.00312-11  1
2011 Shaul P, Green KD, Rutenberg R, Kramer M, Berkov-Zrihen Y, Breiner-Goldstein E, Garneau-Tsodikova S, Fridman M. Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance. Organic & Biomolecular Chemistry. 9: 4057-63. PMID 21365081 DOI: 10.1039/c0ob01133a  1
2011 Bornstein JJ, Eckroat TJ, Houghton JL, Jones CK, Green KD, Garneau-Tsodikova S. Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesterase Medchemcomm. 2: 406-412. DOI: 10.1039/c0md00256a  1
2010 Porter VR, Green KD, Zolova OE, Houghton JL, Garneau-Tsodikova S. Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4'). Biochemical and Biophysical Research Communications. 403: 85-90. PMID 21040710 DOI: 10.1016/j.bbrc.2010.10.119  1
2010 Green KD, Porter VR, Zhang Y, Garneau-Tsodikova S. Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT. Biochemistry. 49: 6219-27. PMID 20560540 DOI: 10.1021/bi1007996  1
2010 Houghton JL, Green KD, Chen W, Garneau-Tsodikova S. The future of aminoglycosides: the end or renaissance? Chembiochem : a European Journal of Chemical Biology. 11: 880-902. PMID 20397253 DOI: 10.1002/cbic.200900779  1
2010 Green KD, Chen W, Houghton JL, Fridman M, Garneau-Tsodikova S. Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides. Chembiochem : a European Journal of Chemical Biology. 11: 119-26. PMID 19899089 DOI: 10.1002/cbic.200900584  1
2010 Green KD, Garneau-Tsodikova S. Posttranslational modification of proteins Comprehensive Natural Products Ii: Chemistry and Biology. 5: 433-468.  1
2009 Green KD, Fridman M, Garneau-Tsodikova S. hChAT: a tool for the chemoenzymatic generation of potential acetyl/butyrylcholinesterase inhibitors. Chembiochem : a European Journal of Chemical Biology. 10: 2191-4. PMID 19637146 DOI: 10.1002/cbic.200900309  1
2009 Green KD, Pflum MK. Exploring kinase cosubstrate promiscuity: monitoring kinase activity through dansylation. Chembiochem : a European Journal of Chemical Biology. 10: 234-7. PMID 19107758 DOI: 10.1002/cbic.200800393  1
2007 Green KD, Pflum MK. Kinase-catalyzed biotinylation for phosphoprotein detection. Journal of the American Chemical Society. 129: 10-1. PMID 17199263 DOI: 10.1021/ja066828o  1
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