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Benjamin Garcia, Ph.D. - Publications

2012- University of Pennsylvania School of Medicine, Philadelphia, PA, United States 

366 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Saiman Y, Shen TD, Lund PJ, Gershuni VM, Jang C, Patel S, Jung S, Furth EE, Friedman ES, Chau L, Garcia BA, Wu GD. Global Microbiota-Dependent Histone Acetylation Patterns are Irreversible and Independent of Short Chain Fatty Acids. Hepatology (Baltimore, Md.). PMID 34233020 DOI: 10.1002/hep.32043  0.72
2021 Saiman Y, Shen TD, Lund PJ, Gershuni VM, Jang C, Patel S, Jung S, Furth EE, Friedman ES, Chau L, Garcia BA, Wu GD. Global Microbiota-Dependent Histone Acetylation Patterns are Irreversible and Independent of Short Chain Fatty Acids. Hepatology (Baltimore, Md.). PMID 34233020 DOI: 10.1002/hep.32043  0.72
2021 Schulze S, Pfeiffer F, Garcia BA, Pohlschroder M. Comprehensive glycoproteomics shines new light on the complexity and extent of glycosylation in archaea. Plos Biology. 19: e3001277. PMID 34138841 DOI: 10.1371/journal.pbio.3001277  0.4
2021 Schulze S, Pfeiffer F, Garcia BA, Pohlschroder M. Comprehensive glycoproteomics shines new light on the complexity and extent of glycosylation in archaea. Plos Biology. 19: e3001277. PMID 34138841 DOI: 10.1371/journal.pbio.3001277  0.4
2021 Faylo JL, van Eeuwen T, Kim HJ, Gorbea Colón JJ, Garcia BA, Murakami K, Christianson DW. Structural insight on assembly-line catalysis in terpene biosynthesis. Nature Communications. 12: 3487. PMID 34108468 DOI: 10.1038/s41467-021-23589-9  0.52
2021 van Eeuwen T, Shim Y, Kim HJ, Zhao T, Basu S, Garcia BA, Kaplan CD, Min JH, Murakami K. Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. Nature Communications. 12: 3338. PMID 34099686 DOI: 10.1038/s41467-021-23684-x  0.52
2021 Riedel SS, Lu C, Xie HM, Nestler K, Vermunt MW, Lenard A, Bennett L, Speck NA, Hanamura I, Lessard JA, Blobel GA, Garcia BA, Bernt KM. Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML. Molecular Cell. PMID 33974912 DOI: 10.1016/j.molcel.2021.04.014  1
2021 Wang SY, Pollina EA, Wang IH, Pino LK, Bushnell HL, Takashima K, Fritsche C, Sabin G, Garcia BA, Greer PL, Greer EL. Role of epigenetics in unicellular to multicellular transition in Dictyostelium. Genome Biology. 22: 134. PMID 33947439 DOI: 10.1186/s13059-021-02360-9  0.72
2021 Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, et al. Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nature Neuroscience. PMID 33833436 DOI: 10.1038/s41593-021-00848-y  1
2021 van Eeuwen T, Li T, Kim HJ, Gorbea Colón JJ, Parker MI, Dunbrack RL, Garcia BA, Tsai KL, Murakami K. Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Science Advances. 7. PMID 33827808 DOI: 10.1126/sciadv.abd4420  0.52
2021 Lu C, Coradin M, Janssen KA, Sidoli S, Garcia BA. Combinatorial Histone H3 Modifications Are Dynamically Altered in Distinct Cell Cycle Phases. Journal of the American Society For Mass Spectrometry. PMID 33818074 DOI: 10.1021/jasms.0c00451  1
2021 Sevilla A, Papatsenko D, Mazloom AR, Xu H, Vasileva A, Unwin RD, LeRoy G, Chen EY, Garrett-Bakelman FE, Lee DF, Trinite B, Webb RL, Wang Z, Su J, Gingold J, ... ... Garcia BA, et al. An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions. Frontiers in Cell and Developmental Biology. 9: 630067. PMID 33816475 DOI: 10.3389/fcell.2021.630067  0.92
2021 Pino LK, Baeza J, Lauman R, Schilling B, Garcia BA. Improved SILAC Quantification with Data-Independent Acquisition to Investigate Bortezomib-Induced Protein Degradation. Journal of Proteome Research. PMID 33764077 DOI: 10.1021/acs.jproteome.0c00938  1
2021 Narapareddy L, Rhon-Calderon EA, Vrooman LA, Baeza J, Nguyen DK, Mesaros C, Lan Y, Garcia BA, Schultz RM, Bartolomei MS. Sex-specific effects of in vitro fertilization on adult metabolic outcomes and hepatic transcriptome and proteome in mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21523. PMID 33734487 DOI: 10.1096/fj.202002744R  0.72
2021 Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, et al. Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nature Neuroscience. PMID 33723435 DOI: 10.1038/s41593-021-00814-8  1
2021 Farhangdoost N, Horth C, Hu B, Bareke E, Chen X, Li Y, Coradin M, Garcia BA, Lu C, Majewski J. Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma. Cell Reports. 34: 108769. PMID 33626351 DOI: 10.1016/j.celrep.2021.108769  1
2021 Porter SS, Liddle JC, Browne K, Pastrana DV, Garcia BA, Buck CB, Weitzman MD, McBride AA. Histone Modifications in Papillomavirus Virion Minichromosomes. Mbio. 12. PMID 33593981 DOI: 10.1128/mBio.03274-20  0.48
2021 Steimle S, van Eeuwen T, Ozturk Y, Kim HJ, Braitbard M, Selamoglu N, Garcia BA, Schneidman-Duhovny D, Murakami K, Daldal F. Cryo-EM structures of engineered active bc-cbb type CIIICIV super-complexes and electronic communication between the complexes. Nature Communications. 12: 929. PMID 33568648 DOI: 10.1038/s41467-021-21051-4  0.52
2021 Schulze S, Igiraneza AB, Kösters M, Leufken J, Leidel SA, Garcia BA, Fufezan C, Pohlschroder M. Enhancing Open Modification Searches via a Combined Approach Facilitated by Ursgal. Journal of Proteome Research. PMID 33514075 DOI: 10.1021/acs.jproteome.0c00799  0.4
2021 Slaughter MJ, Shanle EK, Khan A, Chua KF, Hong T, Boxer LD, Allis CD, Josefowicz SZ, Garcia BA, Rothbart SB, Strahl BD, Davis IJ. HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies. Cell Reports. 34: 108638. PMID 33472068 DOI: 10.1016/j.celrep.2020.108638  0.64
2021 Kim ET, Dybas JM, Kulej K, Reyes ED, Price AM, Akhtar LN, Orr A, Garcia BA, Boutell C, Weitzman MD. Comparative proteomics identifies Schlafen 5 (SLFN5) as a herpes simplex virus restriction factor that suppresses viral transcription. Nature Microbiology. PMID 33432153 DOI: 10.1038/s41564-020-00826-3  0.84
2020 Bhanu NV, Sidoli S, Garcia BA. A Workflow for Ultra-rapid Analysis of Histone Post-translational Modifications with Direct-injection Mass Spectrometry. Bio-Protocol. 10: e3756. PMID 33659415 DOI: 10.21769/BioProtoc.3756  1
2020 White ER, Leace DM, Bedell VM, Bhanu NV, Garcia BA, Dailey WP, Eckenhoff RG. Synthesis and Characterization of a Diazirine-Based Photolabel of the Nonanesthetic Fropofol. Acs Chemical Neuroscience. PMID 33355437 DOI: 10.1021/acschemneuro.0c00667  0.92
2020 Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM. Mechanistic insights into volatile anesthetic modulation of K2P channels. Elife. 9. PMID 33345771 DOI: 10.7554/eLife.59839  0.92
2020 Willcockson MA, Healton SE, Weiss CN, Bartholdy BA, Botbol Y, Mishra LN, Sidhwani DS, Wilson TJ, Pinto HB, Maron MI, Skalina KA, Toro LN, Zhao J, Lee CH, Hou H, ... ... Garcia BA, et al. H1 histones control the epigenetic landscape by local chromatin compaction. Nature. PMID 33299182 DOI: 10.1038/s41586-020-3032-z  1
2020 Bryant L, Li D, Cox SG, Marchione D, Joiner EF, Wilson K, Janssen K, Lee P, March ME, Nair D, Sherr E, Fregeau B, Wierenga KJ, Wadley A, Mancini GMS, ... ... Garcia B, et al. Histone H3.3 beyond cancer: Germline mutations in cause a previously unidentified neurodegenerative disorder in 46 patients. Science Advances. 6. PMID 33268356 DOI: 10.1126/sciadv.abc9207  0.84
2020 Chen CCL, Deshmukh S, Jessa S, Hadjadj D, Lisi V, Andrade AF, Faury D, Jawhar W, Dali R, Suzuki H, Pathania M, A D, Dubois F, Woodward E, Hébert S, ... ... Garcia BA, et al. Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell. PMID 33259802 DOI: 10.1016/j.cell.2020.11.012  0.84
2020 He C, Bozler J, Janssen KA, Wilusz JE, Garcia BA, Schorn AJ, Bonasio R. TET2 chemically modifies tRNAs and regulates tRNA fragment levels. Nature Structural & Molecular Biology. PMID 33230319 DOI: 10.1038/s41594-020-00526-w  1
2020 Harutyunyan AS, Chen H, Lu T, Horth C, Nikbakht H, Krug B, Russo C, Bareke E, Marchione DM, Coradin M, Garcia BA, Jabado N, Majewski J. H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation. Cell Reports. 33: 108390. PMID 33207202 DOI: 10.1016/j.celrep.2020.108390  1
2020 Lu C, Coradin M, Porter EG, Garcia BA. Accelerating the field of epigenetic histone modification through mass spectrometry-based approaches. Molecular & Cellular Proteomics : McP. PMID 33203747 DOI: 10.1074/mcp.R120.002257  1
2020 Li J, Yuan S, Norgard RJ, Yan F, Sun YH, Kim IK, Merrell AJ, Sela Y, Jiang Y, Bhanu NV, Garcia BA, Vonderheide RH, Blanco A, Stanger BZ. Epigenetic and transcriptional control of the epidermal growth factor receptor (EGFR) regulates the tumor immune microenvironment in pancreatic cancer. Cancer Discovery. PMID 33158848 DOI: 10.1158/2159-8290.CD-20-0519  0.92
2020 Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW. Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 33067396 DOI: 10.1073/pnas.2006076117  1
2020 Nativio R, Lan Y, Donahue G, Sidoli S, Berson A, Srinivasan AR, Shcherbakova O, Amlie-Wolf A, Nie J, Cui X, He C, Wang LS, Garcia BA, Trojanowski JQ, Bonini NM, et al. Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease. Nature Genetics. PMID 33033384 DOI: 10.1038/s41588-020-00733-7  1
2020 Millan-Ariño L, Yuan ZF, Oomen ME, Brandenburg S, Chernobrovkin A, Salignon J, Körner L, Zubarev RA, Garcia BA, Riedel CG. Histone Purification Combined with High-Resolution Mass Spectrometry to Examine Histone Post-Translational Modifications and Histone Variants in Caenorhabditis elegans. Current Protocols in Protein Science. 102: e114. PMID 32997895 DOI: 10.1002/cpps.114  0.84
2020 Nativio R, Lan Y, Donahue G, Sidoli S, Berson A, Srinivasan AR, Shcherbakova O, Amlie-Wolf A, Nie J, Cui X, He C, Wang LS, Garcia BA, Trojanowski JQ, Bonini NM, et al. An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease. Nature Genetics. PMID 32989324 DOI: 10.1038/s41588-020-0696-0  1
2020 Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, et al. SIRT1 is downregulated by autophagy in senescence and ageing. Nature Cell Biology. PMID 32989246 DOI: 10.1038/s41556-020-00579-5  1
2020 Khazaei S, De Jay N, Deshmukh S, Hendrikse LD, Jawhar W, Chen CC, Mikael LG, Faury D, Marchione DM, Lanoix J, Bonneil E, Ishii T, Jain SU, Rossokhata K, Sihota TS, ... ... Garcia BA, et al. H3.3G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in Giant Cell Tumour of Bone. Cancer Discovery. PMID 32967858 DOI: 10.1158/2159-8290.CD-20-0461  0.84
2020 Robinson AE, Binek A, Venkatraman V, Searle BC, Holewinski RJ, Rosenberger G, Parker SJ, Basisty N, Xie X, Lund PJ, Saxena G, Mato JM, Garcia BA, Schilling B, Lu SC, et al. Lysine and Arginine Protein Post-translational Modifications by Enhanced DIA Libraries: Quantification in Murine Liver Disease. Journal of Proteome Research. PMID 32966080 DOI: 10.1021/acs.jproteome.0c00685  0.72
2020 Dobenecker MW, Marcello J, Becker A, Rudensky E, Bhanu NV, Carrol T, Garcia BA, Prinjha R, Yurchenko V, Tarakhovsky A. The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice. Febs Letters. PMID 32862441 DOI: 10.1002/1873-3468.13903  0.92
2020 Genoyer E, Kulej K, Hung CT, Thibault PA, Azarm K, Takimoto T, Garcia BA, Lee B, Lakdawala S, Weitzman MD, López CB. The Viral Polymerase Complex Mediates the Interaction of Viral Ribonucleoprotein Complexes with Recycling Endosomes during Sendai Virus Assembly. Mbio. 11. PMID 32843550 DOI: 10.1128/Mbio.02028-20  0.84
2020 Hoshino A, Kim HS, Bojmar L, Gyan KE, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S, Mark MT, Steiner L, Benito-Martin A, Lucotti S, Di Giannatale A, ... ... Garcia BA, et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. PMID 32795414 DOI: 10.1016/J.Cell.2020.07.009  0.68
2020 Kramer MC, Janssen KA, Palos K, Nelson ADL, Vandivier LE, Garcia BA, Lyons E, Beilstein MA, Gregory BD. N-methyladenosine and RNA secondary structure affect transcript stability and protein abundance during systemic salt stress in Arabidopsis. Plant Direct. 4: e00239. PMID 32724893 DOI: 10.1002/pld3.239  1
2020 Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, ... ... Garcia BA, et al. Histone H3.3 phosphorylation amplifies stimulation-induced transcription. Nature. PMID 32699416 DOI: 10.1038/S41586-020-2533-0  1
2020 Herrmann C, Dybas JM, Liddle JC, Price AM, Hayer KE, Lauman R, Purman CE, Charman M, Kim ET, Garcia BA, Weitzman MD. Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing. Nature Microbiology. PMID 32661314 DOI: 10.1038/S41564-020-0750-9  1
2020 Khoa LTP, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, et al. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. PMID 32610040 DOI: 10.1016/J.Stem.2020.06.005  0.92
2020 Rezazadeh S, Yang D, Biashad SA, Firsanov D, Takasugi M, Gilbert M, Tombline G, Bhanu NV, Garcia BA, Seluanov A, Gorbunova V. SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. Aging. 12. PMID 32584788 DOI: 10.18632/aging.103567  0.92
2020 de Lima LP, Poubel SB, Yuan ZF, Rosón JN, de Luna Vitorino FN, Holetz FB, Garcia BA, da Cunha JPC. Improvements on the quantitative analysis of Trypanosoma cruzi histone post translational modifications: Study of changes in epigenetic marks through the parasite's metacyclogenesis and life cycle. Journal of Proteomics. 103847. PMID 32480077 DOI: 10.1016/j.jprot.2020.103847  0.84
2020 Michealraj KA, Kumar SA, Kim LJY, Cavalli FMG, Przelicki D, Wojcik JB, Delaidelli A, Bajic A, Saulnier O, MacLeod G, Vellanki RN, Vladoiu MC, Guilhamon P, Ong W, Lee JJY, ... ... Garcia BA, et al. Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. PMID 32445698 DOI: 10.1016/J.Cell.2020.04.047  0.4
2020 Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K. Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function. Nature Communications. 11: 2219. PMID 32376827 DOI: 10.1038/S41467-020-15902-9  1
2020 Klichinsky M, Ruella M, Shestova O, Lu XM, Best A, Zeeman M, Schmierer M, Gabrusiewicz K, Anderson NR, Petty NE, Cummins KD, Shen F, Shan X, Veliz K, Blouch K, ... ... Garcia BA, et al. Human chimeric antigen receptor macrophages for cancer immunotherapy. Nature Biotechnology. PMID 32361713 DOI: 10.1038/S41587-020-0462-Y  0.84
2020 Zhang X, Baer AG, Price JM, Jones PC, Garcia BJ, Romero J, Cliff AM, Mi W, Brown JB, Jacobson DA, Lydic R, Baghdoyan HA. Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia. Journal of Neurophysiology. PMID 32347157 DOI: 10.1152/Jn.00092.2020  0.56
2020 Chen M, Yan T, Ji L, Yu D, Sidoli S, Yuan Z, Cai C, Chen J, Tang Y, Shen Q, Pan Q, Fu X, Xin K, Liao L, Garcia BA, et al. Comprehensive Map of the Artemisia annua Proteome and Quantification of Differential Protein Expression in Chemotypes Producing High vs Low Content of Artemisinin. Proteomics. e1900310. PMID 32311217 DOI: 10.1002/Pmic.201900310  1
2020 Lauman R, Garcia BA. Unraveling the RNA modification code with mass spectrometry. Molecular Omics. PMID 32285055 DOI: 10.1039/c8mo00247a  1
2020 Bittinger K, Zhao C, Li Y, Ford E, Friedman ES, Ni J, Kulkarni CV, Cai J, Tian Y, Liu Q, Patterson AD, Sarkar D, Chan SHJ, Maranas C, Saha-Shah A, ... ... Garcia BA, et al. Bacterial colonization reprograms the neonatal gut metabolome. Nature Microbiology. PMID 32284564 DOI: 10.1038/S41564-020-0694-0  0.52
2020 Chan JC, Morgan CP, Adrian Leu N, Shetty A, Cisse YM, Nugent BM, Morrison KE, Jašarević E, Huang W, Kanyuch N, Rodgers AB, Bhanu NV, Berger DS, Garcia BA, Ament S, et al. Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment. Nature Communications. 11: 1499. PMID 32198406 DOI: 10.1038/S41467-020-15305-W  0.92
2020 Yuan S, Natesan R, Sanchez-Rivera FJ, Li J, Bhanu NV, Yamazoe T, Lin JH, Merrell AJ, Sela Y, Thomas SK, Jiang Y, Plesset JB, Miller EM, Shi J, Garcia BA, et al. Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression. Cancer Discovery. PMID 32188706 DOI: 10.1158/2159-8290.Cd-19-1299  0.92
2020 Selamoglu N, Önder Ö, Öztürk Y, Khalfaoui-Hassani B, Blaby-Haas CE, Garcia BA, Koch HG, Daldal F. Comparative differential cuproproteomes of Rhodobacter capsulatus reveal novel copper homeostasis related proteins. Metallomics : Integrated Biometal Science. PMID 32149296 DOI: 10.1039/C9Mt00314B  0.56
2020 Gehre M, Bunina D, Sidoli S, Lübke MJ, Diaz N, Trovato M, Garcia BA, Zaugg JB, Noh KM. Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy. Nature Genetics. 52: 273-282. PMID 32139906 DOI: 10.1038/S41588-020-0586-5  1
2020 Coradin M, Mendoza MR, Sidoli S, Alpert AJ, Lu C, Garcia BA. Bullet points to evaluate the performance of the middle-down proteomics workflow for histone modification analysis. Methods (San Diego, Calif.). PMID 32070774 DOI: 10.1016/J.Ymeth.2020.01.013  1
2020 Marchione DM, Ilieva I, Devins K, Sharpe D, Pappin DJ, Garcia BA, Wilson JP, Wojcik JB. HYPERsol: High-Quality Data from Archival FFPE Tissue for Clinical Proteomics. Journal of Proteome Research. PMID 31935107 DOI: 10.1021/acs.jproteome.9b00686  0.84
2020 Bhagwat AR, Le Sage V, Nturibi E, Kulej K, Jones J, Guo M, Tae Kim E, Garcia BA, Weitzman MD, Shroff H, Lakdawala SS. Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association. Nature Communications. 11: 23. PMID 31911620 DOI: 10.1038/S41467-019-13838-3  0.84
2019 Janssen KA, Coradin M, Lu C, Sidoli S, Garcia BA. Quantitation of Single and Combinatorial Histone Modifications by Integrated Chromatography of Bottom-up Peptides and Middle-down Polypeptide Tails. Journal of the American Society For Mass Spectrometry. 30: 2449-2459. PMID 31944722 DOI: 10.1021/jasms.8b06274  1
2019 Iglesias N, Paulo JA, Tatarakis A, Wang X, Edwards AL, Bhanu NV, Garcia BA, Haas W, Gygi SP, Moazed D. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. Molecular Cell. PMID 31784357 DOI: 10.1016/J.Molcel.2019.10.018  0.92
2019 Agosto LM, Gazzara MR, Radens CM, Sidoli S, Baeza J, Garcia BA, Lynch KW. Deep profiling and custom databases improve detection of proteoforms generated by alternative splicing. Genome Research. PMID 31727681 DOI: 10.1101/Gr.248435.119  1
2019 Gowans GJ, Bridgers JB, Zhang J, Dronamraju R, Burnetti A, King DA, Thiengmany AV, Shinsky SA, Bhanu NV, Garcia BA, Buchler NE, Strahl BD, Morrison AJ. Recognition of Histone Crotonylation by Taf14 Links Metabolic State to Gene Expression. Molecular Cell. PMID 31676231 DOI: 10.1016/J.Molcel.2019.09.029  0.92
2019 McKinstry-Wu A, Woll KA, Joseph T, Bu W, White ER, Bhanu NV, Garcia BA, Brannigan G, Dailey WP, Eckenhoff RG. Azi-medetomidine: Synthesis and Characterization of a Novel α2 Adrenergic Photoaffinity Ligand. Acs Chemical Neuroscience. PMID 31638765 DOI: 10.1021/Acschemneuro.9B00484  0.92
2019 Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, ... ... Garcia BA, et al. Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation. Nature Communications. 10: 4724. PMID 31624313 DOI: 10.1038/S41467-019-12551-5  1
2019 Lund PJ, Lehman SM, Garcia BA. Quantitative analysis of global protein lysine methylation by mass spectrometry. Methods in Enzymology. 626: 475-498. PMID 31606088 DOI: 10.1016/Bs.Mie.2019.07.036  0.72
2019 Sidoli S, Lopes M, Lund PJ, Goldman N, Fasolino M, Coradin M, Kulej K, Bhanu NV, Vahedi G, Garcia BA. A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins. Scientific Reports. 9: 13613. PMID 31541121 DOI: 10.1038/S41598-019-49894-4  1
2019 Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, ... ... Garcia BA, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 36: 338-339. PMID 31526762 DOI: 10.1016/j.ccell.2019.08.012  0.84
2019 Janssen KA, Coradin M, Lu C, Sidoli S, Garcia BA. Quantitation of Single and Combinatorial Histone Modifications by Integrated Chromatography of Bottom-up Peptides and Middle-down Polypeptide Tails. Journal of the American Society For Mass Spectrometry. PMID 31512222 DOI: 10.1007/S13361-019-02303-6  1
2019 Lee CH, Yu JR, Granat J, Saldaña-Meyer R, Andrade J, LeRoy G, Jin Y, Lund P, Stafford JM, Garcia BA, Ueberheide B, Reinberg D. Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma. Genes & Development. PMID 31488577 DOI: 10.1101/Gad.328773.119  0.92
2019 Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, ... ... Garcia BA, et al. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape. Nature. PMID 31485078 DOI: 10.1038/S41586-019-1534-3  1
2019 Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, et al. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation. Blood. PMID 31383640 DOI: 10.1182/Blood.2019000578  0.92
2019 Jones P, Garcia BJ, Furches A, Tuskan GA, Jacobson D. Plant Host-Associated Mechanisms for Microbial Selection. Frontiers in Plant Science. 10: 862. PMID 31333701 DOI: 10.3389/fpls.2019.00862  0.4
2019 Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, ... ... Garcia BA, et al. Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31253706 DOI: 10.1073/Pnas.1906896116  1
2019 Yucel N, Wang YX, Mai T, Porpiglia E, Lund PJ, Markov G, Garcia BA, Bendall SC, Angelo M, Blau HM. Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function. Cell Reports. 27: 3939-3955.e6. PMID 31242425 DOI: 10.1016/J.Celrep.2019.05.092  0.72
2019 Saha-Shah A, Esmaeili M, Sidoli S, Hwang H, Yang J, Klein PS, Garcia BA. Single Cell Proteomics to Study Embryonic Asymmetry in Xenopus laevis Embryos. Analytical Chemistry. PMID 31194517 DOI: 10.1021/Acs.Analchem.9B00327  1
2019 Marchione DM, Lisby A, Viaene AN, Santi M, Nasrallah M, Wang LP, Williams EA, Larque AB, Chebib I, Garcia BA, Wojcik JB. Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31175328 DOI: 10.1038/S41379-019-0287-8  0.84
2019 Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, ... Garcia BA, et al. The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Advances. 3: 1586-1597. PMID 31126914 DOI: 10.1182/Bloodadvances.2019032318  0.72
2019 Sidoli S, Kori Y, Lopes M, Yuan ZF, Kim HJ, Kulej K, Janssen KA, Agosto LM, Cunha JPC, Andrews AJ, Garcia BA. One minute analysis of 200 histone post-translational modifications by direct injection mass spectrometry. Genome Research. PMID 31123082 DOI: 10.1101/Gr.247353.118  1
2019 Jain SU, Do TJ, Lund PJ, Rashoff AQ, Diehl KL, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir TW, Garcia BA, Jabado N, Lewis PW. PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Nature Communications. 10: 2146. PMID 31086175 DOI: 10.1038/S41467-019-09981-6  0.72
2019 Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, ... ... Garcia BA, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 35: 782-797.e8. PMID 31085178 DOI: 10.1016/J.Ccell.2019.04.004  0.84
2019 Lund PJ, Kori Y, Zhao X, Sidoli S, Yuan ZF, Garcia BA. Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond. Methods in Molecular Biology (Clifton, N.J.). 1977: 43-70. PMID 30980322 DOI: 10.1007/978-1-4939-9232-4_5  1
2019 Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Reports. 27: 400-415.e5. PMID 30970245 DOI: 10.1016/J.Celrep.2019.03.057  1
2019 Swarr DT, Herriges M, Li S, Morley M, Fernandes S, Sridharan A, Zhou S, Garcia BA, Stewart K, Morrisey EE. The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration. Genes & Development. PMID 30923168 DOI: 10.1101/Gad.320523.118  0.4
2019 Phillips RE, Yang Y, Smith RC, Thompson BM, Yamasaki T, Soto-Feliciano YM, Funato K, Liang Y, Garcia-Bermudez J, Wang X, Garcia BA, Yamasaki K, McDonald JG, Birsoy K, Tabar V, et al. Target identification reveals lanosterol synthase as a vulnerability in glioma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30923116 DOI: 10.1073/Pnas.1820989116  0.88
2019 Hwang H, Jin Z, Krishnamurthy VV, Saha A, Klein PS, Garcia B, Mei W, King ML, Zhang K, Yang J. Novel functions of the ubiquitin-independent proteasome system in regulating germline development. Development (Cambridge, England). PMID 30910828 DOI: 10.1242/Dev.172700  0.48
2019 Yaw AM, Prosser RA, Jones PC, Garcia BJ, Jacobson DA, Glass JD. Epigenetic Effects of Paternal Cocaine on Reward Stimulus Behavior and Accumbens Gene Expression in Mice. Behavioural Brain Research. PMID 30910707 DOI: 10.1016/j.bbr.2019.02.043  0.56
2019 Wojcik JB, Marchione DM, Sidoli S, Djedid A, Lisby A, Majewski J, Garcia BA. Epigenomic reordering induced by Polycomb loss drives oncogenesis but leads to therapeutic vulnerabilities in malignant peripheral nerve sheath tumors. Cancer Research. PMID 30898839 DOI: 10.1158/0008-5472.Can-18-3704  1
2019 Harutyunyan AS, Krug B, Chen H, Papillon-Cavanagh S, Zeinieh M, De Jay N, Deshmukh S, Chen CCL, Belle J, Mikael LG, Marchione DM, Li R, Nikbakht H, Hu B, Cagnone G, ... ... Garcia BA, et al. H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nature Communications. 10: 1262. PMID 30890717 DOI: 10.1038/S41467-019-09140-X  1
2019 Bhanu NV, Sidoli S, Yuan ZF, Molden RC, Garcia BA. Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis. The Journal of Biological Chemistry. PMID 30872405 DOI: 10.1074/Jbc.Ra118.004977  1
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, ... ... Garcia BA, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.92
2019 Zhang Q, McKenzie NJ, Warneford-Thomson R, Gail EH, Flanigan SF, Owen BM, Lauman R, Levina V, Garcia BA, Schittenhelm RB, Bonasio R, Davidovich C. RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2. Nature Structural & Molecular Biology. 26: 237-247. PMID 30833789 DOI: 10.1038/S41594-019-0197-Y  1
2019 Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. Molecular Cell. PMID 30773298 DOI: 10.1016/J.Molcel.2019.01.021  1
2019 Lu C, Sidoli S, Kulej K, Ross K, Wu CH, Garcia BA. Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition. Epigenetics & Chromatin. 12: 11. PMID 30736855 DOI: 10.1186/S13072-019-0256-Y  1
2019 Sidoli S, Trefely S, Garcia BA, Carrer A. Integrated Analysis of Acetyl-CoA and Histone Modification via Mass Spectrometry to Investigate Metabolically Driven Acetylation. Methods in Molecular Biology (Clifton, N.J.). 1928: 125-147. PMID 30725455 DOI: 10.1007/978-1-4939-9027-6_9  1
2019 Carrer A, Trefely S, Zhao S, Campbell S, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, et al. Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis. Cancer Discovery. PMID 30626590 DOI: 10.1158/2159-8290.Cd-18-0567  1
2019 Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, Montavon T, Becker JS, Grindheim JM, Blahnik K, Garcia BA, Tan K, Bonasio R, Jenuwein T, Zaret KS. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science (New York, N.Y.). PMID 30606806 DOI: 10.1126/Science.Aau0583  1
2018 Marchione DM, Garcia BA, Wojcik J. Proteomic approaches for cancer epigenetics research. Expert Review of Proteomics. 1-15. PMID 30482069 DOI: 10.1080/14789450.2019.1550363  0.84
2018 Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, ... ... Garcia BA, et al. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer. Cell. 175: 1244-1258.e26. PMID 30454645 DOI: 10.1016/J.Cell.2018.09.051  0.96
2018 Schon SB, Luense LJ, Wang X, Bartolomei MS, Coutifaris C, Garcia BA, Berger SL. Histone modification signatures in human sperm distinguish clinical abnormalities. Journal of Assisted Reproduction and Genetics. PMID 30397898 DOI: 10.1007/S10815-018-1354-7  0.88
2018 Wang J, Pejaver VR, Dann GP, Wolf MY, Kellis M, Huang Y, Garcia BA, Radivojac P, Kashina A. Target site specificity and in vivo complexity of the mammalian arginylome. Scientific Reports. 8: 16177. PMID 30385798 DOI: 10.1038/S41598-018-34639-6  0.44
2018 Li ML, Jiang Q, Bhanu NV, Wu J, Li W, Garcia BA, Greenberg RA. Phosphorylation of TIP60 suppresses 53BP1 localization at DNA damage sites. Molecular and Cellular Biology. PMID 30297459 DOI: 10.1128/MCB.00209-18  0.92
2018 Karch KR, Coradin M, Zandarashvili L, Kan ZY, Gerace M, Englander SW, Black BE, Garcia BA. Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly. Structure (London, England : 1993). PMID 30293810 DOI: 10.1016/J.Str.2018.08.006  1
2018 Liu X, Cooper DE, Cluntun AA, Warmoes MO, Zhao S, Reid MA, Liu J, Lund PJ, Lopes M, Garcia BA, Wellen KE, Kirsch DG, Locasale JW. Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals. Cell. PMID 30245009 DOI: 10.1016/J.Cell.2018.08.040  0.72
2018 Kreher J, Takasaki T, Cockrum C, Sidoli S, Garcia BA, Jensen ON, Strome S. Distinct Roles of Two Histone Methyltransferases in Transmitting H3K36me3-Based Epigenetic Memory Across Generations in . Genetics. PMID 30217796 DOI: 10.1534/Genetics.118.301353  1
2018 Tuskan GA, Mewalal R, Gunter LE, Palla KJ, Carter K, Jacobson DA, Jones PC, Garcia BJ, Weighill DA, Hyatt PD, Yang Y, Zhang J, Reis N, Chen JG, Muchero W. Defining the genetic components of callus formation: A GWAS approach. Plos One. 13: e0202519. PMID 30118526 DOI: 10.1371/Journal.Pone.0202519  0.56
2018 Greer SM, Sidoli S, Coradin M, Schack Jespersen M, Schwämmle V, Jensen ON, Garcia BA, Brodbelt JS. Extensive Characterization of Heavily Modified Histone Tails by 193 nm Ultraviolet Photodissociation Mass Spectrometry via a Middle-Down Strategy. Analytical Chemistry. PMID 30063333 DOI: 10.1021/Acs.Analchem.8B02320  1
2018 Oksuz O, Narendra V, Lee CH, Descostes N, LeRoy G, Raviram R, Blumenberg L, Karch K, Rocha PP, Garcia BA, Skok JA, Reinberg D. Capturing the Onset of PRC2-Mediated Repressive Domain Formation. Molecular Cell. 70: 1149-1162.e5. PMID 29932905 DOI: 10.1016/J.Molcel.2018.05.023  0.92
2018 Zhang X, Xue C, Lin J, Ferguson JF, Weiner A, Liu W, Han Y, Hinkle C, Li W, Jiang H, Gosai S, Hachet M, Garcia BA, Gregory BD, Soccio RE, et al. Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of in adipocyte metabolism. Science Translational Medicine. 10. PMID 29925637 DOI: 10.1126/Scitranslmed.Aar5987  1
2018 Shastrula PK, Lund PJ, Garcia BA, Janicki SM. Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms. The Journal of Biological Chemistry. PMID 29921582 DOI: 10.1074/jbc.RA118.001845  0.72
2018 Shields EJ, Sheng L, Weiner AK, Garcia BA, Bonasio R. High-Quality Genome Assemblies Reveal Long Non-coding RNAs Expressed in Ant Brains. Cell Reports. 23: 3078-3090. PMID 29874592 DOI: 10.1016/J.Celrep.2018.05.014  0.68
2018 Woll KA, Guzik-Lendrum S, Bensel BM, Bhanu NV, Dailey WP, Garcia BA, Gilbert SP, Eckenhoff RG. An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules. The Journal of Biological Chemistry. PMID 29844014 DOI: 10.1074/Jbc.Ra118.002182  0.92
2018 Yuan ZF, Sidoli S, Marchione DM, Simithy J, Janssen KA, Szurgot MR, Garcia BA. EpiProfile 2.0: A Computational Platform for Processing Epi-Proteomics Mass Spectrometry Data. Journal of Proteome Research. PMID 29790754 DOI: 10.1021/Acs.Jproteome.8B00133  1
2018 Lee CH, Yu JR, Kumar S, Jin Y, LeRoy G, Bhanu N, Kaneko S, Garcia BA, Hamilton AD, Reinberg D. Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin. Molecular Cell. PMID 29681499 DOI: 10.1016/J.Molcel.2018.03.020  0.92
2018 Sadeghi RS, Kulej K, Kathayat RS, Garcia BA, Dickinson BC, Brady DC, Witze E. Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior. Elife. 7. PMID 29648538 DOI: 10.7554/Elife.34362  0.84
2018 Friedman ES, Bittinger K, Esipova TV, Hou L, Chau L, Jiang J, Mesaros C, Lund PJ, Liang X, FitzGerald GA, Goulian M, Lee D, Garcia BA, Blair IA, Vinogradov SA, et al. Microbes vs. chemistry in the origin of the anaerobic gut lumen. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610310 DOI: 10.1073/Pnas.1718635115  0.72
2018 Simithy J, Sidoli S, Garcia BA. Integrating Proteomics and Targeted Metabolomics to Understand Global Changes in Histone Modifications. Proteomics. PMID 29512899 DOI: 10.1002/Pmic.201700309  1
2018 Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG. Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701347R. PMID 29505303 DOI: 10.1096/Fj.201701347R  0.92
2018 Abraham PE, Garcia BJ, Gunter LE, Jawdy SS, Engle N, Yang X, Jacobson DA, Hettich RL, Tuskan GA, Tschaplinski TJ. Quantitative proteome profile of water deficit stress responses in eastern cottonwood (Populus deltoides) leaves. Plos One. 13: e0190019. PMID 29447168 DOI: 10.1371/Journal.Pone.0190019  0.56
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576  0.96
2018 Lin-Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson CL, Sen P, Saffie R, Busino L, Garcia BA, Berger SL, Capell BC. KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis. Genes & Development. PMID 29440247 DOI: 10.1101/Gad.306241.117  1
2018 Lu C, Jain S, Hoelper D, Bechet D, Ran L, Andrulis I, Dickson B, Majewski J, Thompson C, Chi P, Garcia B, Jabado N, Lewis P, Allis CD. Abstract PR12: Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr12  1
2018 Deshmukh S, Khazaei S, Marchione D, Harutyunyan A, Garcia B, Jabado N. Abstract A39: Characterizing the epigenetic effects of the histone 3.3 G34W mutation in giant cell tumors of bone Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-A39  0.4
2018 Chaves-Moreira D, Mitchell M, Sidoli S, Garcia B, Drapkin R. Abstract 5416: Isolation of the PAX8 transcriptional complex to identify novel therapeutic vulnerabilities for ovarian cancer Cancer Research. 78: 5416-5416. DOI: 10.1158/1538-7445.Am2018-5416  1
2017 Becker JS, McCarthy RL, Sidoli S, Donahue G, Kaeding KE, He Z, Lin S, Garcia BA, Zaret KS. Genomic and Proteomic Resolution of Heterochromatin and Its Restriction of Alternate Fate Genes. Molecular Cell. 68: 1023-1037.e15. PMID 29272703 DOI: 10.1016/J.Molcel.2017.11.030  1
2017 Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM. TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling. Current Biology : Cb. PMID 29153328 DOI: 10.1016/J.Cub.2017.10.024  0.76
2017 Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Froehling S, Balachandran S, Skorski T, ... Garcia B, et al. PKC epsilon is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29127121 DOI: 10.1158/1078-0432.Ccr-17-2684  1
2017 Guo Q, Sidoli S, Garcia BA, Zhao X. Assessment of quantification precision of histone post-translational modifications by using an ion trap and down to 50,000 cells as starting material. Journal of Proteome Research. PMID 29121770 DOI: 10.1021/Acs.Jproteome.7B00544  1
2017 Weiner AK, Sidoli S, Diskin SJ, Garcia B. GiaPronto: a one-click graph visualization software for proteomics datasets. Molecular & Cellular Proteomics : McP. PMID 29118029 DOI: 10.1074/Mcp.Tir117.000438  1
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.92
2017 Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nature Communications. 8: 1141. PMID 29070843 DOI: 10.1038/S41467-017-01384-9  1
2017 Karch KR, Langelier MF, Pascal JM, Garcia BA. The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage. Molecular Biosystems. PMID 29058739 DOI: 10.1039/C7Mb00498B  0.96
2017 Warneford-Thomson R, He C, Sidoli S, Garcia BA, Bonasio R. Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions. Journal of Visualized Experiments : Jove. PMID 28994809 DOI: 10.3791/56004  1
2017 Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, ... ... Garcia BA, et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. PMID 28976970 DOI: 10.1038/Nature24050  0.96
2017 Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MD. Identifying host factors associated with DNA replicated during virus infection. Molecular & Cellular Proteomics : McP. PMID 28972080 DOI: 10.1074/Mcp.M117.067116  0.84
2017 Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R. Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling. Biophysical Journal. PMID 28935134 DOI: 10.1016/J.Bpj.2017.08.040  0.92
2017 Armour SM, Remsberg JR, Damle M, Sidoli S, Ho WY, Li Z, Garcia BA, Lazar MA. An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides. Nature Communications. 8: 549. PMID 28916805 DOI: 10.1038/S41467-017-00772-5  1
2017 Shinde MY, Sidoli S, Kulej K, Mallory MJ, Radens CM, Reicherter A, Myers RL, Barash Y, Lynch KW, Garcia BA, Klein PS. Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing. The Journal of Biological Chemistry. PMID 28916722 DOI: 10.1074/Jbc.M117.813527  1
2017 Kori Y, Sidoli S, Yuan ZF, Lund PJ, Zhao X, Garcia BA. Proteome-wide acetylation dynamics in human cells. Scientific Reports. 7: 10296. PMID 28860605 DOI: 10.1038/S41598-017-09918-3  1
2017 Alečković M, Wei Y, LeRoy G, Sidoli S, Liu DD, Garcia BA, Kang Y. Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes & Development. PMID 28827399 DOI: 10.1101/Gad.301937.117  1
2017 Gospocic J, Shields EJ, Glastad KM, Lin Y, Penick CA, Yan H, Mikheyev AS, Linksvayer TA, Garcia BA, Berger SL, Liebig J, Reinberg D, Bonasio R. The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. Cell. 170: 748-759.e12. PMID 28802044 DOI: 10.1016/J.Cell.2017.07.014  0.68
2017 Ebata KT, Mesh K, Liu S, Bilenky M, Fekete A, Acker MG, Hirst M, Garcia BA, Ramalho-Santos M. Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b. Epigenetics & Chromatin. 10: 36. PMID 28706564 DOI: 10.1186/s13072-017-0143-3  0.76
2017 Kim J, Bamlet WR, Oberg AL, Chaffee KG, Donahue G, Cao XJ, Chari S, Garcia BA, Petersen GM, Zaret KS. Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers. Science Translational Medicine. 9. PMID 28701476 DOI: 10.1126/Scitranslmed.Aah5583  1
2017 Ebata KT, Mesh K, Liu S, Bilenky M, Fekete A, Acker MG, Hirst M, Garcia BA, Ramalho-Santos M. Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b. Epigenetics & Chromatin. 10: 36. PMID 28701172 DOI: 10.1186/s13072-017-0143-3  0.76
2017 Sidoli S, Lu C, Coradin M, Wang X, Karch KR, Ruminowicz C, Garcia BA. Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code. Epigenetics & Chromatin. 10: 34. PMID 28683815 DOI: 10.1186/S13072-017-0139-Z  1
2017 Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. PMID 28682306 DOI: 10.1038/Nature23267  0.92
2017 Sidoli S, Garcia BA. Middle-down proteomics: a still unexploited resource for chromatin biology. Expert Review of Proteomics. 1-10. PMID 28649883 DOI: 10.1080/14789450.2017.1345632  1
2017 Wang R, Cao XJ, Kulej K, Liu W, Ma T, MacDonald M, Chiang CM, Garcia BA, You J. Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630312 DOI: 10.1073/pnas.1703071114  1
2017 Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE. The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes & Development. PMID 28546511 DOI: 10.1101/Gad.298018.117  1
2017 Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, ... ... Garcia BA, et al. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors. Cell Reports. 19: 1669-1684. PMID 28538184 DOI: 10.1016/J.Celrep.2017.04.077  0.92
2017 Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD, Garcia BA, Adelman K, Wysocka J. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Molecular Cell. PMID 28483418 DOI: 10.1016/J.Molcel.2017.04.018  0.92
2017 Coradin M, Karch KR, Garcia BA. Monitoring proteolytic processing events by quantitative mass spectrometry. Expert Review of Proteomics. PMID 28395554 DOI: 10.1080/14789450.2017.1316977  1
2017 Coetzee N, Sidoli S, van Biljon R, Painter H, Llinás M, Garcia BA, Birkholtz LM. Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites. Scientific Reports. 7: 607. PMID 28377601 DOI: 10.1038/S41598-017-00687-7  1
2017 Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Photoaffinity ligand for the inhalational anesthetic sevoflurane allows mechanistic insight into potassium channel modulation. Acs Chemical Biology. PMID 28333442 DOI: 10.1021/Acschembio.7B00222  0.4
2017 Klein BJ, Simithy J, Wang X, Ahn J, Andrews FH, Zhang Y, Côté J, Shi X, Garcia BA, Kutateladze TG. Recognition of Histone H3K14 Acylation by MORF. Structure (London, England : 1993). PMID 28286003 DOI: 10.1016/J.Str.2017.02.003  0.96
2017 Feist PE, Sidoli S, Liu X, Schroll MM, Rahmy S, Fujiwara R, Garcia BA, Hummon AB. Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis to Evaluate Epigenetic Drugs. Analytical Chemistry. PMID 28194967 DOI: 10.1021/Acs.Analchem.6B03602  1
2017 Kulej K, Avgousti DC, Sidoli S, Herrmann C, Della Fera AN, Kim ET, Garcia BA, Weitzman MD. Time-resolved global and chromatin proteomics during herpes simplex virus (HSV-1) infection. Molecular & Cellular Proteomics : McP. PMID 28179408 DOI: 10.1074/Mcp.M116.065987  1
2017 Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, et al. Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas. Nature Genetics. PMID 28067913 DOI: 10.1038/Ng.3757  1
2017 Juan AH, Wang S, Ko KD, Zare H, Tsai PF, Feng X, Vivanco KO, Ascoli AM, Gutierrez-Cruz G, Krebs J, Sidoli S, Knight AL, Pedersen RA, Garcia BA, Casellas R, et al. Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. Cell Reports. 18: 297. PMID 28052258 DOI: 10.1016/j.celrep.2016.12.036  1
2017 Kim JJ, Bennett NK, Devita MS, Chahar S, Viswanath S, Lee EA, Jung G, Shao PP, Childers EP, Liu S, Kulesa A, Garcia BA, Becker ML, Hwang NS, Madabhushi A, et al. Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells. Scientific Reports. 7: 39406. PMID 28051095 DOI: 10.1038/Srep39406  0.76
2017 Sidoli S, Garcia BA. Characterization of Individual Histone Posttranslational Modifications and Their Combinatorial Patterns by Mass Spectrometry-Based Proteomics Strategies. Methods in Molecular Biology (Clifton, N.J.). 1528: 121-148. PMID 27854019 DOI: 10.1007/978-1-4939-6630-1_8  1
2017 Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garriga J, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Graña X, Abou-Gharbia M, Issa JJ. Abstract 5064: Identifying novel potential epigenetic anti-cancer drugs from natural compounds using a phenotypic-based screening Cancer Research. 77: 5064-5064. DOI: 10.1158/1538-7445.Am2017-5064  0.32
2017 Venneti S, Bayliss J, Mukherjee P, Lu C, Jain S, Chung C, Martinez D, Sabari B, Margol A, Panwalkar P, Paroloia A, Pekmezci M, Eachin RM, Cieslik M, Tamrazi B, ... Garcia B, et al. Abstract 3863: A subset of poorly prognostic pediatric posterior fossa ependymomas exhibit lowered H3K27me3 and DNA hypomethylation and show epigenetic similarities with H3K27M mutant diffuse intrinsic pontine gliomas Cancer Research. 77: 3863-3863. DOI: 10.1158/1538-7445.Am2017-3863  1
2016 Stankovic A, Guo LY, Mata JF, Bodor DL, Cao XJ, Bailey AO, Shabanowitz J, Hunt DF, Garcia BA, Black BE, Jansen LE. A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly. Molecular Cell. PMID 28017591 DOI: 10.1016/J.Molcel.2016.11.021  1
2016 Sidoli S, Kulej K, Garcia BA. Why proteomics is not the new genomics and the future of mass spectrometry in cell biology. The Journal of Cell Biology. PMID 27956468 DOI: 10.1083/Jcb.201612010  1
2016 Peinado H, Alecˇković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar CM, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, et al. Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature Medicine. 22: 1502. PMID 27923027 DOI: 10.1038/Nm1216-1502B  0.68
2016 Liu MY, Torabifard H, Crawford DJ, DeNizio JE, Cao XJ, Garcia BA, Cisneros GA, Kohli RM. Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine. Nature Chemical Biology. PMID 27918559 DOI: 10.1038/Nchembio.2250  1
2016 Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, et al. Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Science Translational Medicine. 8: 366ra161. PMID 27881822 DOI: 10.1126/Scitranslmed.Aah6904  1
2016 Cao XJ, Garcia BA. Global Proteomics Analysis of Protein Lysine Methylation. Current Protocols in Protein Science. 86: 24.8.1-24.8.19. PMID 27801517 DOI: 10.1002/cpps.16  1
2016 Juan AH, Wang S, Ko KD, Zare H, Tsai PF, Feng X, Vivanco KO, Ascoli AM, Gutierrez-Cruz G, Krebs J, Sidoli S, Knight AL, Pedersen RA, Garcia BA, Casellas R, et al. Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. Cell Reports. 17: 1369-1382. PMID 27783950 DOI: 10.1016/J.Celrep.2016.09.087  1
2016 He C, Sidoli S, Warneford-Thomson R, Tatomer DC, Wilusz JE, Garcia BA, Bonasio R. High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells. Molecular Cell. 64: 416-430. PMID 27768875 DOI: 10.1016/J.Molcel.2016.09.034  1
2016 Josefowicz SZ, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park HS, Garcia BA, Taunton J, Roeder RG, Allis CD. Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. Molecular Cell. 64: 347-361. PMID 27768872 DOI: 10.1016/J.Molcel.2016.09.026  1
2016 Woll KA, Murlidaran S, Pinch BJ, Hénin J, Wang X, Salari R, Covarrubias M, Dailey WP, Brannigan G, Garcia BA, Eckenhoff RG. A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of GABAA Receptor Subunit Binding Selectivity in Synaptosomes. The Journal of Biological Chemistry. PMID 27462076 DOI: 10.1074/Jbc.M116.736975  0.88
2016 Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, ... ... Garcia BA, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biology. 17: 158. PMID 27457071 DOI: 10.1186/S13059-016-1017-X  1
2016 Avgousti DC, Herrmann C, Kulej K, Pancholi NJ, Sekulic N, Petrescu J, Molden RC, Blumenthal D, Paris AJ, Reyes ED, Ostapchuk P, Hearing P, Seeholzer SH, Worthen GS, Black BE, ... Garcia BA, et al. A core viral protein binds host nucleosomes to sequester immune danger signals. Nature. PMID 27362237 DOI: 10.1038/nature18317  1
2016 Luense LJ, Wang X, Schon SB, Weller AH, Lin Shiao E, Bryant JM, Bartolomei MS, Coutifaris C, Garcia BA, Berger SL. Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells. Epigenetics & Chromatin. 9: 24. PMID 27330565 DOI: 10.1186/S13072-016-0072-6  1
2016 Sidoli S, Fujiwara R, Kulej K, Garcia BA. Differential quantification of isobaric phosphopeptides using data-independent acquisition mass spectrometry. Molecular Biosystems. PMID 27301801 DOI: 10.1039/C6Mb00385K  1
2016 Sidoli S, Bhanu NV, Karch KR, Wang X, Garcia BA. Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis. Journal of Visualized Experiments : Jove. PMID 27286567 DOI: 10.3791/54112  1
2016 Tu S, Narendra V, Yamaji M, Vidal SE, Rojas LA, Wang X, Kim SY, Garcia BA, Tuschl T, Stadtfeld M, Reinberg D. Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature. PMID 27281218 DOI: 10.1038/Nature18004  0.32
2016 Lin S, Yuan ZF, Han Y, Marchione DM, Garcia BA. Preferential phosphorylation on old histones during early mitosis in human cells. The Journal of Biological Chemistry. PMID 27226594 DOI: 10.1074/Jbc.M116.726067  1
2016 Sidoli S, Fujiwara R, Garcia BA. Multiplexed data independent acquisition (MSX-DIA) applied by high resolution mass spectrometry improves quantification quality for the analysis of histone peptides. Proteomics. PMID 27193262 DOI: 10.1002/Pmic.201500527  1
2016 Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, ... ... Garcia BA, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science (New York, N.Y.). 352: 844-9. PMID 27174990 DOI: 10.1126/Science.Aac7272  1
2016 Runkle KB, Kharbanda A, Stypulkowski E, Cao XJ, Wang W, Garcia BA, Witze ES. Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling. Molecular Cell. 62: 385-396. PMID 27153536 DOI: 10.1016/J.Molcel.2016.04.003  0.32
2016 Zhou B, Wang J, Lee SY, Xiong J, Bhanu N, Guo Q, Ma P, Sun Y, Rao RC, Garcia BA, Hess JL, Dou Y. PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity. Molecular Cell. PMID 27151440 DOI: 10.1016/j.molcel.2016.03.010  0.84
2016 Wang X, Yuan ZF, Fan J, Karch KR, Ball LE, Denu JM, Garcia BA. A novel quantitative mass spectrometry platform for determining site-specific protein O-GlcNAcylation dynamics. Molecular & Cellular Proteomics : McP. PMID 27114449 DOI: 10.1074/Mcp.O115.049627  0.96
2016 Garcia BA, Luka Z, Loukachevitch LV, Bhanu NV, Wagner C. Folate deficiency affects histone methylation. Medical Hypotheses. 88: 63-7. PMID 26880641 DOI: 10.1016/j.mehy.2015.12.027  1
2016 Gonzales-Cope M, Sidoli S, Bhanu NV, Won KJ, Garcia BA. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells. Bmc Genomics. 17: 95. PMID 26847871 DOI: 10.1186/S12864-016-2414-Y  1
2016 Washburn MP, Zhao Y, Garcia BA. Reshaping the chromatin and epigenetic landscapes with quantitative mass spectrometry. Molecular & Cellular Proteomics : McP. PMID 26814188 DOI: 10.1074/Mcp.E116.058602  1
2016 Arnaudo AM, Link AJ, Garcia BA. Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and their Modifications. Acs Chemical Biology. PMID 26789204 DOI: 10.1021/Acschembio.5B00816  1
2016 Anderson LC, Karch KR, Ugrin SA, Coradin M, English AM, Sidoli S, Shabanowitz J, Garcia BA, Hunt DF. Analyses of Histone Proteoforms Using Front-End Electron Transfer Dissociation-Enabled Orbitrap Instruments. Molecular & Cellular Proteomics : McP. PMID 26785730 DOI: 10.1074/Mcp.O115.053843  1
2016 Olsen JB, Cao XJ, Han B, Chen LH, Horvath A, Richardson TI, Campbell RM, Garcia BA, Nguyen H. Quantitative profiling of the activity of protein lysine methyltransferase SMYD2 using SILAC-based proteomics. Molecular & Cellular Proteomics : McP. PMID 26750096 DOI: 10.1074/mcp.M115.053280  1
2016 Crawford DJ, Liu MY, Nabel CS, Cao XJ, Garcia BA, Kohli RM. Tet2 catalyzes stepwise 5-methylcytosine oxidation by an iterative and de novo mechanism. Journal of the American Chemical Society. PMID 26734843 DOI: 10.1021/Jacs.5B10554  1
2016 Garcia BL, Zhi H, Wager B, Höök M, Skare JT. Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex Plos Pathogens. 12. DOI: 10.1371/journal.ppat.1005404  0.32
2016 Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Abou-Gharbia M, Issa JJ. Abstract B50: A phenotypic screen to identify novel potential epigenetic anticancer drugs from natural compounds Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B50  0.32
2016 Karch KR, Sidoli S, Garcia BA. Identification and Quantification of Histone PTMs Using High-Resolution Mass Spectrometry Methods in Enzymology. DOI: 10.1016/bs.mie.2015.12.007  1
2015 Abdul Halim MF, Karch KR, Zhou Y, Haft DH, Garcia BA, Pohlschroder M. Permuting the PGF-CTERM signature motif blocks both archaeosortase-dependent C-terminal cleavage and prenyl lipid attachment for the Haloferax volcanii S-layer glycoprotein. Journal of Bacteriology. PMID 26712937 DOI: 10.1128/Jb.00849-15  1
2015 Bhanu NV, Sidoli S, Garcia BA. Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics. PMID 26631989 DOI: 10.1002/Pmic.201500231  1
2015 Hu J, Donahue G, Dorsey J, Govin J, Yuan Z, Garcia BA, Shah PP, Berger SL. H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis. Cell Reports. PMID 26628362 DOI: 10.1016/J.Celrep.2015.10.070  1
2015 Han Y, Yuan ZF, Molden RC, Garcia BA. Monitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level. Molecular & Cellular Proteomics : McP. PMID 26543102 DOI: 10.1074/Mcp.M115.053421  1
2015 Vasudevan D, Hickok JR, Bovee RC, Pham V, Mantell LL, Bahroos N, Kanabar P, Cao XJ, Maienschein-Cline M, Garcia B, Thomas DD. Nitric oxide regulates gene expression in cancers by controlling histone posttranslational modifications. Cancer Research. PMID 26542213 DOI: 10.1158/0008-5472.CAN-15-1582  0.32
2015 Jamieson K, Wiles ET, McNaught KJ, Sidoli S, Leggett N, Shao Y, Garcia BA, Selker EU. Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin. Genome Research. PMID 26537359 DOI: 10.1101/Gr.194555.115  1
2015 Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, ... ... Garcia BA, et al. Tumour exosome integrins determine organotropic metastasis. Nature. PMID 26524530 DOI: 10.1038/Nature15756  0.32
2015 Sidoli S, Simithy J, Karch KR, Kulej K, Garcia BA. Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications. Analytical Chemistry. 87: 11448-54. PMID 26505526 DOI: 10.1021/Acs.Analchem.5B03009  1
2015 Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Molecular Cell. PMID 26439302 DOI: 10.1016/J.Molcel.2015.08.019  1
2015 Bondy-Denomy J, Garcia B, Strum S, Du M, Rollins MF, Hidalgo-Reyes Y, Wiedenheft B, Maxwell KL, Davidson AR. Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins. Nature. 526: 136-9. PMID 26416740 DOI: 10.1038/Nature15254  0.32
2015 Önder Ö, Sidoli S, Carroll M, Garcia BA. Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations. Expert Review of Proteomics. 12: 499-517. PMID 26400466 DOI: 10.1586/14789450.2015.1084231  1
2015 Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, ... ... Garcia BA, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. PMID 26366710 DOI: 10.1038/Nm.3943  0.32
2015 Georgoutsou-Spyridonos M, Ricklin D, Pratsinis H, Perivolioti E, Pirmettis I, Garcia BL, Geisbrecht BV, Foukas PG, Lambris JD, Mastellos DC, Sfyroera G. Attenuation of Staphylococcus aureus-Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb. Journal of Immunology (Baltimore, Md. : 1950). 195: 3946-58. PMID 26342032 DOI: 10.4049/Jimmunol.1500966  0.32
2015 Zhao Y, Garcia BA. Comprehensive Catalog of Currently Documented Histone Modifications. Cold Spring Harbor Perspectives in Biology. 7: a025064. PMID 26330523 DOI: 10.1101/Cshperspect.A025064  1
2015 Moraes I, Yuan ZF, Liu S, Souza GM, Garcia BA, Casas-Mollano JA. Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane. Plos One. 10: e0134586. PMID 26226299 DOI: 10.1371/journal.pone.0134586  1
2015 Sidoli S, Garcia BA. Properly reading the histone code by MS based proteomics. Proteomics. PMID 26223514 DOI: 10.1002/Pmic.201500298  1
2015 Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, ... ... Garcia BA, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/J.Neuron.2015.06.014  1
2015 Kulej K, Avgousti DC, Weitzman MD, Garcia BA. Characterization of histone post-translational modifications during virus infection using mass spectrometry-based proteomics. Methods (San Diego, Calif.). PMID 26093074 DOI: 10.1016/j.ymeth.2015.06.008  1
2015 Summers BJ, Garcia BL, Woehl JL, Ramyar KX, Yao X, Geisbrecht BV. Identification of peptidic inhibitors of the alternative complement pathway based on Staphylococcus aureus SCIN proteins. Molecular Immunology. PMID 26052070 DOI: 10.1016/J.Molimm.2015.05.012  0.32
2015 Peixoto LL, Wimmer ME, Poplawski SG, Tudor JC, Kenworthy CA, Liu S, Mizuno K, Garcia BA, Zhang NR, Giese K, Abel T. Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. Bmc Genomics. 16: S5. PMID 26040834 DOI: 10.1186/1471-2164-16-S5-S5  0.76
2015 Aguilar M, Aisa D, Alpat B, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, et al. Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station. Physical Review Letters. 114: 171103. PMID 25978222 DOI: 10.1103/Physrevlett.114.171103  0.88
2015 Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA. Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Epigenetics & Chromatin. 8: 15. PMID 25922622 DOI: 10.1186/S13072-015-0006-8  1
2015 Ziehr B, Lenarcic E, Vincent HA, Cecil C, Garcia B, Shenk T, Moorman NJ. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 15: 1983-94. PMID 25894605 DOI: 10.1002/Pmic.201400616  1
2015 Won KJ, Choi I, LeRoy G, Zee BM, Sidoli S, Gonzales-Cope M, Garcia BA. Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants. Epigenetics & Chromatin. 8: 13. PMID 25878728 DOI: 10.1186/S13072-015-0005-9  1
2015 Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, ... ... Garcia BA, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. The Journal of Biological Chemistry. 290: 13641-53. PMID 25825497 DOI: 10.1074/Jbc.M114.626861  1
2015 Yuan ZF, Lin S, Molden RC, Cao XJ, Bhanu NV, Wang X, Sidoli S, Liu S, Garcia BA. EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. Molecular & Cellular Proteomics : McP. 14: 1696-707. PMID 25805797 DOI: 10.1074/Mcp.M114.046011  1
2015 Sidoli S, Lin S, Karch KR, Garcia BA. Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry. Analytical Chemistry. 87: 3129-33. PMID 25719549 DOI: 10.1021/Acs.Analchem.5B00072  1
2015 Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Characterization of BRD4 during mammalian postmeiotic sperm development. Molecular and Cellular Biology. 35: 1433-48. PMID 25691659 DOI: 10.1128/Mcb.01328-14  1
2015 Huang H, Lin S, Garcia BA, Zhao Y. Quantitative proteomic analysis of histone modifications. Chemical Reviews. 115: 2376-418. PMID 25688442 DOI: 10.1021/Cr500491U  1
2015 Laurent B, Ruitu L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y. A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation. Molecular Cell. 57: 957-70. PMID 25684206 DOI: 10.1016/J.Molcel.2015.01.010  1
2015 Sidoli S, Yuan ZF, Lin S, Karch K, Wang X, Bhanu N, Arnaudo AM, Britton LM, Cao XJ, Gonzales-Cope M, Han Y, Liu S, Molden RC, Wein S, Afjehi-Sadat L, ... Garcia BA, et al. Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. Proteomics. 15: 1459-69. PMID 25641854 DOI: 10.1002/Pmic.201400483  1
2015 Sidoli S, Lin S, Xiong L, Bhanu NV, Karch KR, Johansen E, Hunter C, Mollah S, Garcia BA. SWATH Analysis for Characterization and Quantification of Histone Post-translational Modifications. Molecular & Cellular Proteomics : McP. PMID 25636311 DOI: 10.1074/Mcp.O114.046102  1
2015 Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Developmental Cell. 32: 168-80. PMID 25625206 DOI: 10.1016/J.Devcel.2014.12.009  1
2015 Kang S, Tsai LT, Zhou Y, Evertts A, Xu S, Griffin MJ, Issner R, Whitton HJ, Garcia BA, Epstein CB, Mikkelsen TS, Rosen ED. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nature Cell Biology. 17: 44-56. PMID 25503565 DOI: 10.1038/Ncb3080  1
2015 Garrigues JM, Sidoli S, Garcia BA, Strome S. Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2. Genome Research. 25: 76-88. PMID 25467431 DOI: 10.1101/Gr.180489.114  1
2015 Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, et al. Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Blood. 125: 346-57. PMID 25395428 DOI: 10.1182/Blood-2014-06-581082  1
2015 Mazur PK, Reynoird N, Khatri P, Butte AJ, Wilkinson A, Garcia B, Liu S, Vermeulen M, Jansen PWTC, Tummino PJ, Kruger RG, Aller GSV, Barbash O, Huddleston M, Gozani O, et al. Abstract A23: SMYD3 links methylation of MAP3K2 to Ras-driven tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A23  0.76
2014 Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K. BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nature Structural & Molecular Biology. 21: 1047-57. PMID 25383670 DOI: 10.1038/Nsmb.2912  1
2014 Woehl JL, Stapels DA, Garcia BL, Ramyar KX, Keightley A, Ruyken M, Syriga M, Sfyroera G, Weber AB, Zolkiewski M, Ricklin D, Lambris JD, Rooijakkers SH, Geisbrecht BV. The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase. Journal of Immunology (Baltimore, Md. : 1950). 193: 6161-71. PMID 25381436 DOI: 10.4049/Jimmunol.1401600  0.32
2014 Maze I, Shen L, Zhang B, Garcia BA, Shao N, Mitchell A, Sun H, Akbarian S, Allis CD, Nestler EJ. Analytical tools and current challenges in the modern era of neuroepigenomics. Nature Neuroscience. 17: 1476-90. PMID 25349914 DOI: 10.1038/Nn.3816  1
2014 Karch KR, Zee BM, Garcia BA. High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. Journal of Proteome Research. 13: 6152-9. PMID 25325711 DOI: 10.1021/Pr500902F  1
2014 Beck DB, Narendra V, Drury WJ, Casey R, Jansen PW, Yuan ZF, Garcia BA, Vermeulen M, Bonasio R. In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions. Journal of Proteome Research. 13: 6135-43. PMID 25311790 DOI: 10.1021/Pr500196B  1
2014 Huang H, Sabari BR, Garcia BA, Allis CD, Zhao Y. SnapShot: histone modifications. Cell. 159: 458-458.e1. PMID 25303536 DOI: 10.1016/J.Cell.2014.09.037  1
2014 Yuan ZF, Lin S, Molden RC, Garcia BA. Evaluation of proteomic search engines for the analysis of histone modifications. Journal of Proteome Research. 13: 4470-8. PMID 25167464 DOI: 10.1021/Pr5008015  1
2014 Mews P, Zee BM, Liu S, Donahue G, Garcia BA, Berger SL. Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence. Molecular and Cellular Biology. 34: 3968-80. PMID 25154414 DOI: 10.1128/Mcb.00763-14  1
2014 Britton LM, Sova P, Belisle S, Liu S, Chan EY, Katze MG, Garcia BA. A proteomic glimpse into the initial global epigenetic changes during HIV infection. Proteomics. 14: 2226-30. PMID 25116026 DOI: 10.1002/pmic.201400116  1
2014 Molden RC, Garcia BA. Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 77: 23.7.1-23.7.28. PMID 25081742 DOI: 10.1002/0471140864.Ps2307S77  1
2014 Lin S, Wein S, Gonzales-Cope M, Otte GL, Yuan ZF, Afjehi-Sadat L, Maile T, Berger SL, Rush J, Lill JR, Arnott D, Garcia BA. Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. Molecular & Cellular Proteomics : McP. 13: 2450-66. PMID 25000943 DOI: 10.1074/mcp.O113.036459  1
2014 Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, ... ... Garcia BA, et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabolism. 20: 306-19. PMID 24998913 DOI: 10.1016/J.Cmet.2014.06.004  1
2014 O'Connor CM, DiMaggio PA, Shenk T, Garcia BA. Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. Molecular & Cellular Proteomics : McP. 13: 2399-410. PMID 24987098 DOI: 10.1074/Mcp.M114.039792  1
2014 Yuan ZF, Arnaudo AM, Garcia BA. Mass spectrometric analysis of histone proteoforms. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 7: 113-28. PMID 24896311 DOI: 10.1146/annurev-anchem-071213-015959  1
2014 Su Z, Boersma MD, Lee JH, Oliver SS, Liu S, Garcia BA, Denu JM. ChIP-less analysis of chromatin states. Epigenetics & Chromatin. 7: 7. PMID 24872844 DOI: 10.1186/1756-8935-7-7  1
2014 Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 510: 283-7. PMID 24847881 DOI: 10.1038/Nature13320  1
2014 Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors. Plos One. 9: e95535. PMID 24740276 DOI: 10.1371/journal.pone.0095535  1
2014 Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors. Plos One. 9: e90095. PMID 24587223 DOI: 10.1371/Journal.Pone.0090095  1
2014 Molden RC, Goya J, Khan Z, Garcia BA. Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination. Molecular & Cellular Proteomics : McP. 13: 1106-18. PMID 24532841 DOI: 10.1074/Mcp.O113.036145  1
2014 Fan J, Shan C, Kang HB, Elf S, Xie J, Tucker M, Gu TL, Aguiar M, Lonning S, Chen H, Mohammadi M, Britton LM, Garcia BA, Alečković M, Kang Y, et al. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Molecular Cell. 53: 534-48. PMID 24486017 DOI: 10.1016/J.Molcel.2013.12.026  1
2014 Rhoads TW, Rose CM, Bailey DJ, Riley NM, Molden RC, Nestler AJ, Merrill AE, Smith LM, Hebert AS, Westphall MS, Pagliarini DJ, Garcia BA, Coon JJ. Neutron-encoded mass signatures for quantitative top-down proteomics. Analytical Chemistry. 86: 2314-9. PMID 24475910 DOI: 10.1021/Ac403579S  1
2014 Bhanu NV, Garcia BA. Proteomic interrogation of human chromatin protein states Systems Analysis of Chromatin-Related Protein Complexes in Cancer. 2147483647: 149-175. DOI: 10.1007/978-1-4614-7931-4_8  1
2013 Karch KR, Denizio JE, Black BE, Garcia BA. Identification and interrogation of combinatorial histone modifications. Frontiers in Genetics. 4: 264. PMID 24391660 DOI: 10.3389/Fgene.2013.00264  1
2013 Simeoni F, Tasselli L, Tanaka S, Villanova L, Hayashi M, Kubota K, Isono F, Garcia BA, Michishita-Kioi E, Chua KF. Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling. Scientific Reports. 3: 3085. PMID 24169447 DOI: 10.1038/Srep03085  1
2013 Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. H3R42me2a is a histone modification with positive transcriptional effects. Proceedings of the National Academy of Sciences of the United States of America. 110: 14894-9. PMID 23980157 DOI: 10.1073/pnas.1312925110  1
2013 Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1101-13. PMID 23949383 DOI: 10.4161/Epi.26025  1
2013 Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA. H4K20 methylation regulates quiescence and chromatin compaction. Molecular Biology of the Cell. 24: 3025-37. PMID 23924899 DOI: 10.1091/Mbc.E12-07-0529  1
2013 Arnaudo AM, Garcia BA. Proteomic characterization of novel histone post-translational modifications. Epigenetics & Chromatin. 6: 24. PMID 23916056 DOI: 10.1186/1756-8935-6-24  1
2013 Han Y, Garcia BA. Combining genomic and proteomic approaches for epigenetics research. Epigenomics. 5: 439-52. PMID 23895656 DOI: 10.2217/Epi.13.37  1
2013 Leroy G, Dimaggio PA, Chan EY, Zee BM, Blanco MA, Bryant B, Flaniken IZ, Liu S, Kang Y, Trojer P, Garcia BA. A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics & Chromatin. 6: 20. PMID 23826629 DOI: 10.1186/1756-8935-6-20  1
2013 Stadler SC, Vincent CT, Fedorov VD, Patsialou A, Cherrington BD, Wakshlag JJ, Mohanan S, Zee BM, Zhang X, Garcia BA, Condeelis JS, Brown AM, Coonrod SA, Allis CD. Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 11851-6. PMID 23818587 DOI: 10.1073/Pnas.1308362110  1
2013 Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature Cell Biology. 15: 872-82. PMID 23748610 DOI: 10.1038/Ncb2768  1
2013 Cao XJ, Arnaudo AM, Garcia BA. Large-scale global identification of protein lysine methylation in vivo. Epigenetics. 8: 477-85. PMID 23644510 DOI: 10.4161/epi.24547  1
2013 Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 497: 652. PMID 23615611 DOI: 10.1038/Nature12164  1
2013 Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (New York, N.Y.). 340: 857-61. PMID 23539183 DOI: 10.1126/Science.1232245  1
2013 Evertts AG, Zee BM, Dimaggio PA, Gonzales-Cope M, Coller HA, Garcia BA. Quantitative dynamics of the link between cellular metabolism and histone acetylation. The Journal of Biological Chemistry. 288: 12142-51. PMID 23482559 DOI: 10.1074/Jbc.M112.428318  1
2013 Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nature Communications. 4: 1565. PMID 23463008 DOI: 10.1038/Ncomms2582  1
2013 Cao XJ, Zee BM, Garcia BA. Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. Methods in Molecular Biology (Clifton, N.J.). 977: 299-313. PMID 23436372 DOI: 10.1007/978-1-62703-284-1_24  1
2013 Zee BM, Garcia BA. Validation of protein acetylation by mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 981: 1-11. PMID 23381849 DOI: 10.1007/978-1-62703-305-3_1  1
2013 Afjehi-Sadat L, Garcia BA. Comprehending dynamic protein methylation with mass spectrometry. Current Opinion in Chemical Biology. 17: 12-9. PMID 23333572 DOI: 10.1016/j.cbpa.2012.12.023  1
2013 Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S. SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics. 8: 177-83. PMID 23324626 DOI: 10.4161/Epi.23416  1
2013 Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nature Structural & Molecular Biology. 20: 202-9. PMID 23295261 DOI: 10.1038/Nsmb.2477  1
2013 Baliban RC, Sakellari D, Li Z, Guzman YA, Garcia BA, Floudas CA. Discovery of biomarker combinations that predict periodontal health or disease with high accuracy from GCF samples based on high-throughput proteomic analysis and mixed-integer linear optimization. Journal of Clinical Periodontology. 40: 131-9. PMID 23190455 DOI: 10.1111/Jcpe.12037  1
2013 Wu Y, DiMaggio PA, Perlman DH, Zakian VA, Garcia BA. Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. Journal of Proteome Research. 12: 316-27. PMID 23181431 DOI: 10.1021/Pr300408V  1
2013 Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (Nature Communications (2013) 4, (1565) DOI: 10.1038/ncomms2582) Nature Communications. 4. DOI: 10.1038/Ncomms3090  1
2012 Voigt P, LeRoy G, Drury WJ, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Asymmetrically modified nucleosomes. Cell. 151: 181-93. PMID 23021224 DOI: 10.1016/J.Cell.2012.09.002  1
2012 Lin S, Garcia BA. Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods in Enzymology. 512: 3-28. PMID 22910200 DOI: 10.1016/B978-0-12-391940-3.00001-9  1
2012 LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA. Proteo-Genomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins Genome Biology. R68. PMID 22897906 DOI: 10.1186/Gb-2012-13-8-R68  1
2012 Baliban RC, Dimaggio PA, Plazas-Mayorca MD, Garcia BA, Floudas CA. PILOT_PROTEIN: identification of unmodified and modified proteins via high-resolution mass spectrometry and mixed-integer linear optimization. Journal of Proteome Research. 11: 4615-29. PMID 22788846 DOI: 10.1021/Pr300418J  1
2012 Rothbart SB, Lin S, Britton LM, Krajewski K, Keogh MC, Garcia BA, Strahl BD. Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Scientific Reports. 2: 489. PMID 22761995 DOI: 10.1038/Srep00489  1
2012 Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 487: 114-8. PMID 22722849 DOI: 10.1038/Nature11043  1
2012 Zee BM, Garcia BA. Discovery of lysine post-translational modifications through mass spectrometric detection. Essays in Biochemistry. 52: 147-63. PMID 22708569 DOI: 10.1042/Bse0520147  1
2012 Blanco MA, LeRoy G, Khan Z, Alečković M, Zee BM, Garcia BA, Kang Y. Global secretome analysis identifies novel mediators of bone metastasis. Cell Research. 22: 1339-55. PMID 22688892 DOI: 10.1038/Cr.2012.89  1
2012 Lee SH, Kalejta RF, Kerry J, Semmes OJ, O'Connor CM, Khan Z, Garcia BA, Shenk T, Murphy E. BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9575-80. PMID 22645331 DOI: 10.1073/Pnas.1207496109  1
2012 Peinado H, Ale?kovi? M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature Medicine. 18: 883-91. PMID 22635005 DOI: 10.1038/Nm.2753  1
2012 Chicas A, Kapoor A, Wang X, Aksoy O, Evertts AG, Zhang MQ, Garcia BA, Bernstein E, Lowe SW. H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 109: 8971-6. PMID 22615382 DOI: 10.1073/Pnas.1119836109  1
2012 Zee BM, Britton LM, Wolle D, Haberman DM, Garcia BA. Origins and formation of histone methylation across the human cell cycle. Molecular and Cellular Biology. 32: 2503-14. PMID 22547680 DOI: 10.1128/Mcb.06673-11  1
2012 Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos AF, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, et al. Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics. 7: 340-3. PMID 22419068 DOI: 10.4161/Epi.19506  1
2012 Ratnakumar K, Duarte LF, LeRoy G, Hasson D, Smeets D, Vardabasso C, Bönisch C, Zeng T, Xiang B, Zhang DY, Li H, Wang X, Hake SB, Schermelleh L, Garcia BA, et al. ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes & Development. 26: 433-8. PMID 22391447 DOI: 10.1101/Gad.179416.111  1
2012 Yu Y, Song C, Zhang Q, DiMaggio PA, Garcia BA, York A, Carey MF, Grunstein M. Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Molecular Cell. 46: 7-17. PMID 22387026 DOI: 10.1016/J.Molcel.2012.01.019  1
2012 Green EM, Mas G, Young NL, Garcia BA, Gozani O. Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. Nature Structural & Molecular Biology. 19: 361-3. PMID 22343720 DOI: 10.1038/Nsmb.2252  1
2012 Baliban RC, Sakellari D, Li Z, DiMaggio PA, Garcia BA, Floudas CA. Novel protein identification methods for biomarker discovery via a proteomic analysis of periodontally healthy and diseased gingival crevicular fluid samples. Journal of Clinical Periodontology. 39: 203-12. PMID 22092770 DOI: 10.1111/J.1600-051X.2011.01805.X  1
2012 Watson AM, Richer MG, Bloom JS, Butler NR, Ceseña U, Clark D, Colorado E, Córdova A, Farah A, Fox-Machado L, Fox OD, García B, Georgiev LN, González JJ, Guisa G, et al. Automation of the OAN/SPM 1.5-meter Johnson telescope for operations with RATIR Proceedings of Spie - the International Society For Optical Engineering. 8444. DOI: 10.1117/12.926927  0.76
2011 Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Molecular Cell. 44: 609-20. PMID 22099308 DOI: 10.1016/J.Molcel.2011.08.042  1
2011 Britton LM, Gonzales-Cope M, Zee BM, Garcia BA. Breaking the histone code with quantitative mass spectrometry. Expert Review of Proteomics. 8: 631-43. PMID 21999833 DOI: 10.1586/Epr.11.47  1
2011 Zee BM, Young NL, Garcia BA. Quantitative proteomic approaches to studying histone modifications. Current Chemical Genomics. 5: 106-14. PMID 21966350 DOI: 10.2174/1875397301005010106  1
2011 Torrente MP, Zee BM, Young NL, Baliban RC, LeRoy G, Floudas CA, Hake SB, Garcia BA. Proteomic interrogation of human chromatin. Plos One. 6: e24747. PMID 21935452 DOI: 10.1371/Journal.Pone.0024747  1
2011 Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celià-Terrassa T, Mercatali L, Khan Z, Goodarzi H, Hua Y, Wei Y, Hu G, Garcia BA, Ragoussis J, Amadori D, et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Medicine. 17: 1101-8. PMID 21822286 DOI: 10.1038/Nm.2401  1
2011 Waldmann T, Izzo A, Kamieniarz K, Richter F, Vogler C, Sarg B, Lindner H, Young NL, Mittler G, Garcia BA, Schneider R. Methylation of H2AR29 is a novel repressive PRMT6 target. Epigenetics & Chromatin. 4: 11. PMID 21774791 DOI: 10.1186/1756-8935-4-11  1
2011 Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, ... ... Garcia BA, et al. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nature Chemical Biology. 7: 566-74. PMID 21743462 DOI: 10.1038/Nchembio.599  1
2011 Wu L, Zee BM, Wang Y, Garcia BA, Dou Y. The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Molecular Cell. 43: 132-44. PMID 21726816 DOI: 10.1016/J.Molcel.2011.05.015  1
2011 Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. The Journal of Biological Chemistry. 286: 28833-43. PMID 21708950 DOI: 10.1074/Jbc.M111.233932  1
2011 Arnaudo AM, Molden RC, Garcia BA. Revealing histone variant induced changes via quantitative proteomics. Critical Reviews in Biochemistry and Molecular Biology. 46: 284-94. PMID 21526979 DOI: 10.3109/10409238.2011.577052  1
2011 Hergeth SP, Dundr M, Tropberger P, Zee BM, Garcia BA, Daujat S, Schneider R. Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. Journal of Cell Science. 124: 1623-8. PMID 21511733 DOI: 10.1242/Jcs.084947  1
2011 Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, ... ... Garcia BA, et al. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nature Immunology. 12: 29-36. PMID 21131967 DOI: 10.1038/Ni.1968  1
2011 Young NL, Garcia BA. Chapter 4: Liquid chromatography-mass spectrometry of intact proteins Rsc Chromatography Monographs. 38-55.  1
2010 Garcia BA, Cooper HJ, Dorrestein PC, Tang K, Ueberheide BM. Proteomics. Journal of Biomedicine & Biotechnology. 2010: 453045. PMID 21541239 DOI: 10.1155/2010/453045  1
2010 Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature. 468: 1105-9. PMID 21179167 DOI: 10.1038/Nature09590  0.92
2010 Zee BM, Levin RS, Dimaggio PA, Garcia BA. Global turnover of histone post-translational modifications and variants in human cells. Epigenetics & Chromatin. 3: 22. PMID 21134274 DOI: 10.1186/1756-8935-3-22  1
2010 Binda O, LeRoy G, Bua DJ, Garcia BA, Gozani O, Richard S. Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics. 5: 767-75. PMID 21124070 DOI: 10.4161/Epi.5.8.13278  0.92
2010 Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 466: 774-8. PMID 20686576 DOI: 10.1038/Nature09301  1
2010 Young NL, Dimaggio PA, Garcia BA. The significance, development and progress of high-throughput combinatorial histone code analysis. Cellular and Molecular Life Sciences : Cmls. 67: 3983-4000. PMID 20683756 DOI: 10.1007/S00018-010-0475-7  1
2010 Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, et al. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 466: 503-7. PMID 20622853 DOI: 10.1038/Nature09261  1
2010 Plazas-Mayorca MD, Bloom JS, Zeissler U, Leroy G, Young NL, DiMaggio PA, Krugylak L, Schneider R, Garcia BA. Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown. Molecular Biosystems. 6: 1719-29. PMID 20577673 DOI: 10.1039/C003307C  1
2010 Weiss T, Hergeth S, Zeissler U, Izzo A, Tropberger P, Zee BM, Dundr M, Garcia BA, Daujat S, Schneider R. Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics & Chromatin. 3: 7. PMID 20334638 DOI: 10.1186/1756-8935-3-7  1
2010 Young NL, Plazas-Mayorca MD, DiMaggio PA, Flaniken IZ, Beltran AJ, Mishra N, LeRoy G, Floudas CA, Garcia BA. Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a. Journal of the American Society For Mass Spectrometry. 21: 960-70. PMID 20202861 DOI: 10.1016/J.Jasms.2010.01.020  1
2010 Garske AL, Oliver SS, Wagner EK, Musselman CA, LeRoy G, Garcia BA, Kutateladze TG, Denu JM. Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nature Chemical Biology. 6: 283-90. PMID 20190764 DOI: 10.1038/Nchembio.319  0.92
2010 Young NL, Plazas-Mayorca MD, Garcia BA. Systems-wide proteomic characterization of combinatorial post-translational modification patterns. Expert Review of Proteomics. 7: 79-92. PMID 20121478 DOI: 10.1586/epr.09.100  1
2010 Evertts AG, Zee BM, Garcia BA. Modern approaches for investigating epigenetic signaling pathways. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 927-33. PMID 20110548 DOI: 10.1152/Japplphysiol.00007.2010  1
2010 Baliban RC, DiMaggio PA, Plazas-Mayorca MD, Young NL, Garcia BA, Floudas CA. A novel approach for untargeted post-translational modification identification using integer linear optimization and tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 9: 764-79. PMID 20103568 DOI: 10.1074/Mcp.M900487-Mcp200  1
2010 Zee BM, Levin RS, Xu B, LeRoy G, Wingreen NS, Garcia BA. In vivo residue-specific histone methylation dynamics. The Journal of Biological Chemistry. 285: 3341-50. PMID 19940157 DOI: 10.1074/Jbc.M109.063784  1
2010 Zee BM, Garcia BA. Electron transfer dissociation facilitates sequencing of adenosine diphosphate-ribosylated peptides. Analytical Chemistry. 82: 28-31. PMID 19928949 DOI: 10.1021/Ac902134Y  1
2010 Blanco MA, LeRoy G, Zee B, Aleckovic M, Garcia B, Kang Y. Abstract B7: The bone metastasis secretome: Identification of potential therapeutic targets via high-throughput proteomics Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-B7  0.92
2009 Plazas-Mayorca MD, Zee BM, Young NL, Fingerman IM, LeRoy G, Briggs SD, Garcia BA. One-pot shotgun quantitative mass spectrometry characterization of histones. Journal of Proteome Research. 8: 5367-74. PMID 19764812 DOI: 10.1021/Pr900777E  1
2009 Khan Z, Bloom JS, Garcia BA, Singh M, Kruglyak L. Protein quantification across hundreds of experimental conditions. Proceedings of the National Academy of Sciences of the United States of America. 106: 15544-8. PMID 19717460 DOI: 10.1073/Pnas.0904100106  0.44
2009 DiMaggio PA, Young NL, Baliban RC, Garcia BA, Floudas CA. A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron transfer dissociation tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 8: 2527-43. PMID 19666874 DOI: 10.1074/Mcp.M900144-Mcp200  0.92
2009 Basu A, Rose KL, Zhang J, Beavis RC, Ueberheide B, Garcia BA, Chait B, Zhao Y, Hunt DF, Segal E, Allis CD, Hake SB. Proteome-wide prediction of acetylation substrates. Proceedings of the National Academy of Sciences of the United States of America. 106: 13785-90. PMID 19666589 DOI: 10.1073/Pnas.0906801106  1
2009 Young NL, DiMaggio PA, Plazas-Mayorca MD, Baliban RC, Floudas CA, Garcia BA. High throughput characterization of combinatorial histone codes. Molecular & Cellular Proteomics : McP. 8: 2266-84. PMID 19654425 DOI: 10.1074/Mcp.M900238-Mcp200  1
2009 LeRoy G, Weston JT, Zee BM, Young NL, Plazas-Mayorca MD, Garcia BA. Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Molecular & Cellular Proteomics : McP. 8: 2432-42. PMID 19567367 DOI: 10.1074/Mcp.M900160-Mcp200  1
2009 Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27. PMID 19250903 DOI: 10.1016/J.Molcel.2009.02.004  1
2009 El Gazzar M, Yoza BK, Chen X, Garcia BA, Young NL, McCall CE. Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Molecular and Cellular Biology. 29: 1959-71. PMID 19158276 DOI: 10.1128/Mcb.01862-08  1
2009 Boyne MT, Garcia BA, Li M, Zamdborg L, Wenger CD, Babai S, Kelleher NL. Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval. Journal of Proteome Research. 8: 374-9. PMID 19053528 DOI: 10.1021/Pr800635M  1
2009 Nicklay JJ, Shechter D, Chitta RK, Garcia BA, Shabanowitz J, Allis CD, Hunt DF. Analysis of histones in Xenopus laevis. II. mass spectrometry reveals an index of cell type-specific modifications on H3 and H4. The Journal of Biological Chemistry. 284: 1075-85. PMID 18957437 DOI: 10.1074/Jbc.M807274200  1
2008 Duncan EM, Muratore-Schroeder TL, Cook RG, Garcia BA, Shabanowitz J, Hunt DF, Allis CD. Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell. 135: 284-94. PMID 18957203 DOI: 10.1016/j.cell.2008.09.055  1
2008 Garcia BA, Thomas CE, Kelleher NL, Mizzen CA. Tissue-specific expression and post-translational modification of histone H3 variants. Journal of Proteome Research. 7: 4225-36. PMID 18700791 DOI: 10.1021/Pr800044Q  1
2007 Pesavento JJ, Garcia BA, Streeky JA, Kelleher NL, Mizzen CA. Mild performic acid oxidation enhances chromatographic and top down mass spectrometric analyses of histones. Molecular & Cellular Proteomics : McP. 6: 1510-26. PMID 17569892 DOI: 10.1074/Mcp.M600404-Mcp200  1
2007 Garcia BA, Pesavento JJ, Mizzen CA, Kelleher NL. Pervasive combinatorial modification of histone H3 in human cells. Nature Methods. 4: 487-9. PMID 17529979 DOI: 10.1038/Nmeth1052  1
2007 Garcia BA, Mollah S, Ueberheide BM, Busby SA, Muratore TL, Shabanowitz J, Hunt DF. Chemical derivatization of histones for facilitated analysis by mass spectrometry. Nature Protocols. 2: 933-8. PMID 17446892 DOI: 10.1038/Nprot.2007.106  1
2007 Luo W, Peterson A, Garcia BA, Coombs G, Kofahl B, Heinrich R, Shabanowitz J, Hunt DF, Yost HJ, Virshup DM. Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. The Embo Journal. 26: 1511-21. PMID 17318175 DOI: 10.1038/Sj.Emboj.7601607  1
2007 Garcia BA, Hake SB, Diaz RL, Kauer M, Morris SA, Recht J, Shabanowitz J, Mishra N, Strahl BD, Allis CD, Hunt DF. Organismal differences in post-translational modifications in histones H3 and H4. The Journal of Biological Chemistry. 282: 7641-55. PMID 17194708 DOI: 10.1074/Jbc.M607900200  1
2007 Morris SA, Rao B, Garcia BA, Hake SB, Diaz RL, Shabanowitz J, Hunt DF, Allis CD, Lieb JD, Strahl BD. Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. The Journal of Biological Chemistry. 282: 7632-40. PMID 17189264 DOI: 10.1074/Jbc.M607909200  1
2007 Garcia BA, Shabanowitz J, Hunt DF. Characterization of histones and their post-translational modifications by mass spectrometry. Current Opinion in Chemical Biology. 11: 66-73. PMID 17157550 DOI: 10.1016/J.Cbpa.2006.11.022  1
2007 Garcia BA, Siuti N, Thomas CE, Mizzen CA, Kelleher NL. Characterization of neurohistone variants and post-translational modifications by electron capture dissociation mass spectrometry International Journal of Mass Spectrometry. 259: 184-196. DOI: 10.1016/J.Ijms.2006.07.022  1
2006 Li Y, Kao GD, Garcia BA, Shabanowitz J, Hunt DF, Qin J, Phelan C, Lazar MA. A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes & Development. 20: 2566-79. PMID 16980585 DOI: 10.1101/Gad.1455006  1
2006 Garcia BA, Platt MD, Born TL, Shabanowitz J, Marcus NA, Hunt DF. Protein profile of osteoarthritic human articular cartilage using tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 20: 2999-3006. PMID 16969770 DOI: 10.1002/Rcm.2692  1
2006 Klimowski LK, Garcia BA, Shabanowitz J, Hunt DF, Virshup DM. Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling. The Febs Journal. 273: 4594-602. PMID 16965538 DOI: 10.1111/J.1742-4658.2006.05462.X  1
2006 Garcia BA, Joshi S, Thomas CE, Chitta RK, Diaz RL, Busby SA, Andrews PC, Ogorzalek Loo RR, Shabanowitz J, Kelleher NL, Mizzen CA, Allis CD, Hunt DF. Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila. Molecular & Cellular Proteomics : McP. 5: 1593-609. PMID 16835217 DOI: 10.1074/Mcp.M600086-Mcp200  1
2006 Swiatek W, Kang H, Garcia BA, Shabanowitz J, Coombs GS, Hunt DF, Virshup DM. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. The Journal of Biological Chemistry. 281: 12233-41. PMID 16513652 DOI: 10.1074/Jbc.M510580200  1
2006 Hake SB, Garcia BA, Duncan EM, Kauer M, Dellaire G, Shabanowitz J, Bazett-Jones DP, Allis CD, Hunt DF. Expression patterns and post-translational modifications associated with mammalian histone H3 variants. The Journal of Biological Chemistry. 281: 559-68. PMID 16267050 DOI: 10.1074/Jbc.M509266200  1
2005 Garcia BA, Busby SA, Shabanowitz J, Hunt DF, Mishra N. Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. Journal of Proteome Research. 4: 2032-42. PMID 16335948 DOI: 10.1021/Pr050188R  1
2005 Fischle W, Tseng BS, Dormann HL, Ueberheide BM, Garcia BA, Shabanowitz J, Hunt DF, Funabiki H, Allis CD. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature. 438: 1116-22. PMID 16222246 DOI: 10.1038/Nature04219  1
2005 Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. The platelet microparticle proteome. Journal of Proteome Research. 4: 1516-21. PMID 16212402 DOI: 10.1021/Pr0500760  1
2005 Garcia BA, Barber CM, Hake SB, Ptak C, Turner FB, Busby SA, Shabanowitz J, Moran RG, Allis CD, Hunt DF. Modifications of human histone H3 variants during mitosis. Biochemistry. 44: 13202-13. PMID 16185088 DOI: 10.1021/Bi050906N  1
2005 Hake SB, Garcia BA, Kauer M, Baker SP, Shabanowitz J, Hunt DF, Allis CD. Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 102: 6344-9. PMID 15851689 DOI: 10.1073/Pnas.0502413102  1
2005 Garcia BA, Shabanowitz J, Hunt DF. Analysis of protein phosphorylation by mass spectrometry. Methods (San Diego, Calif.). 35: 256-64. PMID 15722222 DOI: 10.1016/J.Ymeth.2004.08.017  1
2005 Yang CS, Vitto MJ, Busby SA, Garcia BA, Kesler CT, Gioeli D, Shabanowitz J, Hunt DF, Rundell K, Brautigan DL, Paschal BM. Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor. Molecular and Cellular Biology. 25: 1298-308. PMID 15684382 DOI: 10.1128/Mcb.25.4.1298-1308.2005  1
2004 Johnson L, Mollah S, Garcia BA, Muratore TL, Shabanowitz J, Hunt DF, Jacobsen SE. Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Research. 32: 6511-8. PMID 15598823 DOI: 10.1093/Nar/Gkh992  0.92
2004 Garcia BA, Busby SA, Barber CM, Shabanowitz J, Allis CD, Hunt DF. Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. Journal of Proteome Research. 3: 1219-27. PMID 15595731 DOI: 10.1021/Pr0498887  1
2004 Syka JE, Marto JA, Bai DL, Horning S, Senko MW, Schwartz JC, Ueberheide B, Garcia B, Busby S, Muratore T, Shabanowitz J, Hunt DF. Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. Journal of Proteome Research. 3: 621-6. PMID 15253445 DOI: 10.1021/Pr0499794  1
2002 Garcia BA, Heaney PJ, Tang K. Improvement of the MALDI-TOF analysis of DNA with thin-layer matrix preparation. Analytical Chemistry. 74: 2083-91. PMID 12033310 DOI: 10.1021/ac011089+  1
2002 Tang K, Shahgholi M, Garcia BA, Heaney PJ, Cantor CR, Scott LG, Williamson JR. Improvement in the apparent mass resolution of oligonucleotides by using 12C/14N-enriched samples. Analytical Chemistry. 74: 226-31. PMID 11795798 DOI: 10.1021/Ac010804C  1
2001 Shahgholi M, Garcia BA, Chiu NH, Heaney PJ, Tang K. Sugar additives for MALDI matrices improve signal allowing the smallest nucleotide change (A:T) in a DNA sequence to be resolved. Nucleic Acids Research. 29: E91. PMID 11574693 DOI: 10.1093/nar/29.19.e91  1
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