Daniel T. Chiu - Publications

Affiliations: 
2000- Chemistry University of Washington, Seattle, Seattle, WA 
Area:
Analytical, Biological, Materials, and Physical Chemistry, Nanotechnology
Website:
http://depts.washington.edu/chem/people/faculty/chiu.html

253 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Qin YL, Wu L, Wang J, Han R, Shen J, Wang J, Xu S, Paguirigan AL, Smith JL, Radich JP, Chiu DT. A Fluorescence-Activated Single-Droplet Dispenser for High Accuracy Single-Droplet and Single-Cell Sorting and Dispensing. Analytical Chemistry. PMID 31050286 DOI: 10.1021/acs.analchem.9b01017  0.8
2019 Chen L, Chen D, Jiang Y, Zhang J, Yu J, DuFort CC, Hingorani SR, Zhang X, Wu C, Chiu DT. BODIPY-Based Donor/Donor-Acceptor System: Towards Highly Efficient Long Wavelength-Excitable Near-IR Polymer Dots with Narrow and Strong Absorption Features. Angewandte Chemie (International Ed. in English). PMID 30912228 DOI: 10.1002/anie.201902077  1
2019 Hassan AM, Wu X, Jarrett JW, Xu S, Yu J, Miller DR, Perillo EP, Liu YL, Chiu DT, Yeh HC, Dunn AK. Polymer dots enable deep multiphoton fluorescence imaging of microvasculature. Biomedical Optics Express. 10: 584-599. PMID 30800501 DOI: 10.1364/BOE.10.000584  1
2019 Kreutz JE, Wang J, Sheen AM, Thompson AM, Staheli JP, Dyen MR, Feng Q, Chiu DT. Self-digitization chip for quantitative detection of human papillomavirus gene using digital LAMP. Lab On a Chip. PMID 30734822 DOI: 10.1039/c8lc01223g  0.76
2019 Yen GS, Fujimoto BS, Schneider T, Kreutz JE, Chiu DT. Statistical Analysis of Non-Uniform Volume Distributions for Droplet-based Digital PCR Assays. Journal of the American Chemical Society. PMID 30605325 DOI: 10.1021/jacs.8b09073  0.92
2018 Wang J, Kreutz JE, Thompson AM, Qin Y, Sheen AM, Wang J, Wu L, Xu S, Chang M, Raugi DN, Smith RA, Gottlieb GS, Chiu DT. SD-chip enabled quantitative detection of HIV RNA using digital nucleic acid sequence-based amplification (dNASBA). Lab On a Chip. PMID 30351338 DOI: 10.1039/c8lc00956b  0.8
2018 Kuo CT, Wu IC, Chen L, Yu J, Wu L, Chiu DT. Improving the Photostability of Semiconducting Polymer Dots Using Buffers. Analytical Chemistry. PMID 30277754 DOI: 10.1021/acs.analchem.8b03104  1
2018 Jauregui R, Srinivasan S, Vojtech LN, Gammill HS, Chiu DT, Hladik F, Stayton P, Lai JJ. Temperature-Responsive Magnetic Nanoparticles for Enabling Affinity Separation of Extracellular Vesicles. Acs Applied Materials & Interfaces. PMID 30152229 DOI: 10.1021/acsami.8b09751  0.36
2018 Wu X, DeGottardi Q, Wu IC, Wu L, Yu J, Kwok WW, Chiu DT. Ratiometric Barcoding for Mass Cytometry. Analytical Chemistry. PMID 30139253 DOI: 10.1021/acs.analchem.8b03201  1
2018 Qin Y, Wu L, Schneider T, Yen G, Wang J, Xu S, Li M, Paguirigan AL, Smith JL, Radich JP, Anand RK, Chiu DT. Self-Digitization Dielectrophoretic (SD-DEP) Chip for High Efficiency Single-Cell Capture, On-Demand Compartmentalization, and Downstream Nucleic-Acid Analysis. Angewandte Chemie (International Ed. in English). PMID 30003660 DOI: 10.1002/anie.201807314  0.84
2018 Andronico LA, Chen L, Mirasoli M, Guardigli M, Quintavalla A, Lombardo M, Trombini C, Chiu DT, Roda A. Thermochemiluminescent semiconducting polymer dots as sensitive nanoprobes for reagentless immunoassay. Nanoscale. PMID 29995031 DOI: 10.1039/c8nr03092h  0.84
2018 Thompson AM, Smith JL, Monroe LD, Kreutz JE, Schneider T, Fujimoto BS, Chiu DT, Radich JP, Paguirigan AL. Self-digitization chip for single-cell genotyping of cancer-related mutations. Plos One. 13: e0196801. PMID 29718986 DOI: 10.1371/journal.pone.0196801  0.92
2018 Sun K, Yang Y, Zhou H, Yin S, Qin W, Yu J, Chiu DT, Yuan Z, Zhang X, Wu C. Ultrabright Polymer-Dot Transducer Enabled Wireless Glucose Monitoring via a Smartphone. Acs Nano. PMID 29694016 DOI: 10.1021/acsnano.8b02188  1
2018 Chen H, Fang X, Jin Y, Hu X, Yin M, Men X, Chen N, Fan C, Chiu DT, Wan Y, Wu C. Semiconducting Polymer Nanocavities: Porogenic Synthesis, Tunable Host-Guest Interactions, and Enhanced Drug/siRNA Delivery. Small (Weinheim An Der Bergstrasse, Germany). e1800239. PMID 29682859 DOI: 10.1002/smll.201800239  1
2018 Jung SR, Han R, Sun W, Jiang Y, Fujimoto BS, Yu J, Kuo CT, Rong Y, Zhou XH, Chiu DT. A single-molecule flow platform for the quantification of biomolecules attached to single nanoparticles. Analytical Chemistry. PMID 29672026 DOI: 10.1021/acs.analchem.8b00024  1
2018 Chen D, Yuan Y, Yu J, Chiu DT, Wu C. Purification of Semiconducting Polymer Dots by Size Exclusion Chromatography Prior to Cytotoxicity Assay and Stem Cell Labeling. Analytical Chemistry. PMID 29569904 DOI: 10.1021/acs.analchem.8b00095  1
2017 Chiu DT, Wu X, Degottardi Q, Wu IC, Yu J, Wu L, Ye F, Kuo CT, Kwok WW. Lanthanide-Coordinated Semiconducting Polymer Dots that Function for both Flow Cytometry and Mass Cytometry. Angewandte Chemie (International Ed. in English). PMID 28941061 DOI: 10.1002/anie.201708463  1
2017 Jung SR, Fujimoto BS, Chiu DT. Quantitative microscopy based on single-molecule fluorescence. Current Opinion in Chemical Biology. 39: 64-73. PMID 28623730 DOI: 10.1016/j.cbpa.2017.06.004  0.92
2017 Chen D, Wu IC, Liu Z, Tang Y, Chen H, Yu J, Wu C, Chiu DT. Semiconducting polymer dots with bright narrow-band emission at 800 nm for biological applications. Chemical Science. 8: 3390-3398. PMID 28507710 DOI: 10.1039/c7sc00441a  1
2017 Kuo CT, Peng HS, Rong Y, Yu J, Sun W, Fujimoto BS, Chiu DT. Optically Encoded Semiconducting Polymer Dots with Single-Wavelength Excitation for Barcoding and Tracking of Single Cells. Analytical Chemistry. PMID 28499337 DOI: 10.1021/acs.analchem.7b01214  1
2017 Wu L, Wu IC, DuFort CC, Carlson MA, Wu X, Chen L, Kuo CT, Qin Y, Yu J, Hingorani SR, Chiu DT. A Photostable Ratiometric Pdot Probe for In Vitro and In Vivo Imaging of Hypochlorous Acid. Journal of the American Chemical Society. PMID 28459559 DOI: 10.1021/jacs.7b01545  1
2017 Yu J, Rong Y, Kuo CT, Zhou XH, Chiu DT. Recent Advances in the Development of Highly Luminescent Semiconducting Polymer Dots and Nanoparticles for Biological Imaging and Medicine. Analytical Chemistry. 89: 42-56. PMID 28105818 DOI: 10.1021/acs.analchem.6b04672  1
2016 Wu X, Wu L, Wu IC, Chiu DT. Copper (II)-doped semiconducting polymer dots for nitroxyl imaging in live cells. Rsc Advances. 6: 103618-103621. PMID 28529727 DOI: 10.1039/C6RA20439B  1
2016 Sun K, Tang Y, Li Q, Yin S, Qin W, Yu J, Chiu DT, Liu Y, Yuan Z, Zhang X, Wu C. In Vivo Dynamic Monitoring of Small Molecules with Implantable Polymer-Dot Transducer. Acs Nano. PMID 27303785 DOI: 10.1021/acsnano.6b02386  1
2016 Kuo CT, Thompson AM, Gallina ME, Ye F, Johnson ES, Sun W, Zhao M, Yu J, Wu IC, Fujimoto B, DuFort CC, Carlson MA, Hingorani SR, Paguirigan AL, Radich JP, ... Chiu DT, et al. Optical painting and fluorescence activated sorting of single adherent cells labelled with photoswitchable Pdots. Nature Communications. 7: 11468. PMID 27118210 DOI: 10.1038/ncomms11468  1
2016 Yen GS, Edgar JS, Yoon SH, Huang Y, Heron SR, Chiu DT, Goodlett DR. Polydimethylsiloxane microchannel coupled to surface acoustic wave nebulization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 30: 1096-100. PMID 27003047 DOI: 10.1002/rcm.7531  1
2015 Johnson ES, Anand RK, Chiu DT. Improved Detection by Ensemble-Decision Aliquot Ranking of Circulating Tumor Cells with Low Numbers of a Targeted Surface Antigen. Analytical Chemistry. 87: 9389-95. PMID 26302174 DOI: 10.1021/acs.analchem.5b02241  1
2015 Zhao M, Wei B, Nelson WC, Schiro PG, Chiu DT. Simultaneous and selective isolation of multiple subpopulations of rare cells from peripheral blood using ensemble-decision aliquot ranking (eDAR). Lab On a Chip. PMID 26160592 DOI: 10.1039/c5lc00384a  1
2015 Ye F, Smith PB, Chiu DT. Ultrasensitive Protein Detection on Dot Blots and Western Blots with Semiconducting Polymer Dots. Methods in Molecular Biology (Clifton, N.J.). 1314: 131-7. PMID 26139261 DOI: 10.1007/978-1-4939-2718-0_14  1
2015 Ye F, White CC, Jin Y, Hu X, Hayden S, Zhang X, Gao X, Kavanagh TJ, Chiu DT. Toxicity and oxidative stress induced by semiconducting polymer dots in RAW264.7 mouse macrophages. Nanoscale. 7: 10085-93. PMID 25978523 DOI: 10.1039/c5nr01857a  1
2015 Yang HC, Cheng ML, Hua YS, Wu YH, Lin HR, Liu HY, Ho HY, Chiu DT. Glucose 6-phosphate dehydrogenase knockdown enhances IL-8 expression in HepG2 cells via oxidative stress and NF-κB signaling pathway. Journal of Inflammation (London, England). 12: 34. PMID 25945076 DOI: 10.1186/s12950-015-0078-z  0.8
2015 Wang Y, Cai L, Wu Y, Wilson RF, Weston C, Fawole O, Bleich SN, Cheskin LJ, Showell NN, Lau BD, Chiu DT, Zhang A, Segal J. What childhood obesity prevention programmes work? A systematic review and meta-analysis. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 16: 547-65. PMID 25893796 DOI: 10.1111/obr.12277  0.72
2015 Fang C, Wang K, Stephen ZR, Mu Q, Kievit FM, Chiu DT, Press OW, Zhang M. Temozolomide nanoparticles for targeted glioblastoma therapy. Acs Applied Materials & Interfaces. 7: 6674-82. PMID 25751368 DOI: 10.1021/am5092165  1
2015 Zhang Y, Ye F, Sun W, Yu J, Wu IC, Rong Y, Zhang Y, Chiu DT. Light-induced Crosslinkable Semiconducting Polymer Dots. Chemical Science (Royal Society of Chemistry : 2010). 6: 2102-2109. PMID 25709806 DOI: 10.1039/C4SC03959A  1
2015 Anand RK, Johnson ES, Chiu DT. Negative dielectrophoretic capture and repulsion of single cells at a bipolar electrode: the impact of faradaic ion enrichment and depletion. Journal of the American Chemical Society. 137: 776-83. PMID 25562315 DOI: 10.1021/ja5102689  1
2015 Tang HY, Ho HY, Wu PR, Chen SH, Kuypers FA, Cheng ML, Chiu DT. Inability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbance. Antioxidants & Redox Signaling. 22: 744-59. PMID 25556665 DOI: 10.1089/ars.2014.6142  0.8
2015 Mehta K, Pierce P, Chiu DT, Thanik V. The effect of residency and fellowship type on hand surgery clinical practice patterns. Plastic and Reconstructive Surgery. 135: 179-86. PMID 25539305 DOI: 10.1097/PRS.0000000000000786  0.32
2015 Peng HS, Chiu DT. Soft fluorescent nanomaterials for biological and biomedical imaging. Chemical Society Reviews. 44: 4699-722. PMID 25531691 DOI: 10.1039/c4cs00294f  1
2015 Ye F, Sun W, Zhang Y, Wu C, Zhang X, Yu J, Rong Y, Zhang M, Chiu DT. Single-chain semiconducting polymer dots. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 499-505. PMID 25521606 DOI: 10.1021/la5038684  1
2015 Wu IC, Yu J, Ye F, Rong Y, Gallina ME, Fujimoto BS, Zhang Y, Chan YH, Sun W, Zhou XH, Wu C, Chiu DT. Squaraine-based polymer dots with narrow, bright near-infrared fluorescence for biological applications. Journal of the American Chemical Society. 137: 173-8. PMID 25494172 DOI: 10.1021/ja5123045  1
2014 Rong Y, Yu J, Zhang X, Sun W, Ye F, Wu IC, Zhang Y, Hayden S, Zhang Y, Wu C, Chiu DT. Yellow Fluorescent Semiconducting Polymer Dots with High Brightness, Small Size, and Narrow Emission for Biological Applications. Acs Macro Letters. 3: 1051-1054. PMID 25419486 DOI: 10.1021/mz500383c  1
2014 Thompson AM, Gansen A, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT. Self-digitization microfluidic chip for absolute quantification of mRNA in single cells. Analytical Chemistry. 86: 12308-14. PMID 25390242 DOI: 10.1021/ac5035924  1
2014 Liu D, Hakimi B, Volny M, Rolfs J, Anand RK, Turecek F, Chiu DT. Modulating patterns of two-phase flow with electric fields. Biomicrofluidics. 8: 044106. PMID 25379091 DOI: 10.1063/1.4891099  0.64
2014 Chiu DT, Chung B. Discussion: measuring outcomes and determining long-term disability after revision amputation for treatment of traumatic finger and thumb amputation injuries. Plastic and Reconstructive Surgery. 134: 756e-757e. PMID 25347650 DOI: 10.1097/PRS.0000000000000693  0.32
2014 Chiu DT, Wei YH. Special issue on "Oxidative stress and mitochondrial alterations in aging and disease". Free Radical Research. 48: 967-9. PMID 25113533 DOI: 10.3109/10715762.2014.948536  0.8
2014 Chang K, Liu Z, Chen H, Sheng L, Zhang SX, Chiu DT, Yin S, Wu C, Qin W. Conjugated polymer dots for ultra-stable full-color fluorescence patterning. Small (Weinheim An Der Bergstrasse, Germany). 10: 4270-5. PMID 25048985 DOI: 10.1002/smll.201401436  1
2014 Li Q, Zhang J, Sun W, Yu J, Wu C, Qin W, Chiu DT. Europium-complex-grafted polymer dots for amplified quenching and cellular imaging applications. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 8607-14. PMID 24976495 DOI: 10.1021/la501876m  1
2014 Chiu DT. Oxidative stress in biology and medicine. Biomedical Journal. 37: 97-8. PMID 24923565 DOI: 10.4103/2319-4170.134087  0.8
2014 Thompson AM, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT. Microfluidics for single-cell genetic analysis. Lab On a Chip. 14: 3135-42. PMID 24789374 DOI: 10.1039/c4lc00175c  1
2014 Ye F, Wu C, Sun W, Yu J, Zhang X, Rong Y, Zhang Y, Wu IC, Chan YH, Chiu DT. Semiconducting polymer dots with monofunctional groups. Chemical Communications (Cambridge, England). 50: 5604-7. PMID 24728589 DOI: 10.1039/c4cc01689k  1
2014 Ho HY, Cheng ML, Chiu DT. Glucose-6-phosphate dehydrogenase--beyond the realm of red cell biology. Free Radical Research. 48: 1028-48. PMID 24720642 DOI: 10.3109/10715762.2014.913788  0.8
2014 Chiu DT, Shapiro NI, Sun BC, Mottley JL, Grossman SA. Are echocardiography, telemetry, ambulatory electrocardiography monitoring, and cardiac enzymes in emergency department patients presenting with syncope useful tests? A preliminary investigation. The Journal of Emergency Medicine. 47: 113-8. PMID 24698512 DOI: 10.1016/j.jemermed.2014.01.018  0.4
2014 Volný M, Rolfs J, Hakimi B, Fry?ák P, Schneider T, Liu D, Yen G, Chiu DT, Ture?ek F. Nanoliter segmented-flow sampling mass spectrometry with online compartmentalization. Analytical Chemistry. 86: 3647-52. PMID 24625074 DOI: 10.1021/ac500365r  1
2014 Patel A, Pierce P, Chiu DT. A fascial band implicated in Wartenberg syndrome. Plastic and Reconstructive Surgery. 133: 440e-442e. PMID 24572905 DOI: 10.1097/01.prs.0000438497.39857.97  0.32
2014 Wiener Z, Chiu DT, Shapiro NI, Grossman SA. Substance abuse in emergency department patients with unexplained syncope. Internal and Emergency Medicine. 9: 331-4. PMID 24297764 DOI: 10.1007/s11739-013-1026-7  0.4
2014 Haddock NT, Weinstein AL, Sinno S, Chiu DT. Thrombin and topical local anesthetic for postoperative pain management. Annals of Plastic Surgery. 73: 30-2. PMID 23241808 DOI: 10.1097/SAP.0b013e31826cafae  0.32
2013 Zhang X, Yu J, Rong Y, Ye F, Chiu DT, Uvdal K. High-intensity near-IR fluorescence in semiconducting polymer dots achieved by cascade FRET strategy. Chemical Science. 4: 2143-2151. PMID 28959389 DOI: 10.1039/C3SC50222H  1
2013 Schneider T, Yen GS, Thompson AM, Burnham DR, Chiu DT. Self-digitization of samples into a high-density microfluidic bottom-well array. Analytical Chemistry. 85: 10417-23. PMID 24099270 DOI: 10.1021/ac402383n  1
2013 Zhao M, Nelson WC, Wei B, Schiro PG, Hakimi BM, Johnson ES, Anand RK, Gyurkey GS, White LM, Whiting SH, Coveler AL, Chiu DT. New generation of ensemble-decision aliquot ranking based on simplified microfluidic components for large-capacity trapping of circulating tumor cells. Analytical Chemistry. 85: 9671-7. PMID 24087951 DOI: 10.1021/ac401985r  1
2013 Sun W, Yu J, Deng R, Rong Y, Fujimoto B, Wu C, Zhang H, Chiu DT. Semiconducting polymer dots doped with europium complexes showing ultranarrow emission and long luminescence lifetime for time-gated cellular imaging. Angewandte Chemie (International Ed. in English). 52: 11294-7. PMID 24030955 DOI: 10.1002/anie.201304822  1
2013 Min J, Chiu DT, Wang Y. Variation in the heritability of body mass index based on diverse twin studies: a systematic review. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 14: 871-82. PMID 23980914 DOI: 10.1111/obr.12065  0.72
2013 Li Q, Sun K, Chang K, Yu J, Chiu DT, Wu C, Qin W. Ratiometric luminescent detection of bacterial spores with terbium chelated semiconducting polymer dots. Analytical Chemistry. 85: 9087-91. PMID 23964730 DOI: 10.1021/ac4016616  1
2013 Zhao M, Wei B, Chiu DT. Imaging multiple biomarkers in captured rare cells by sequential immunostaining and photobleaching. Methods (San Diego, Calif.). 64: 108-13. PMID 23954571 DOI: 10.1016/j.ymeth.2013.08.006  1
2013 Chiu DT, Guerra S, Chung B. Pre- and/or postsurgical administration of estradiol benzoate increases rates of skin flap viability in female rats. Aesthetic Plastic Surgery. 37: 1010-1. PMID 23943049 DOI: 10.1007/s00266-013-0152-y  0.32
2013 Zhang Y, Yu J, Gallina ME, Sun W, Rong Y, Chiu DT. Highly luminescent, fluorinated semiconducting polymer dots for cellular imaging and analysis. Chemical Communications (Cambridge, England). 49: 8256-8. PMID 23925590 DOI: 10.1039/c3cc44048f  1
2013 Zeigler MB, Sun W, Rong Y, Chiu DT. Hybrid semiconducting polymer nanoparticles as polarization-sensitive fluorescent probes. Journal of the American Chemical Society. 135: 11453-6. PMID 23895535 DOI: 10.1021/ja404719f  1
2013 Cheng ML, Ho HY, Lin HY, Lai YC, Chiu DT. Effective NET formation in neutrophils from individuals with G6PD Taiwan-Hakka is associated with enhanced NADP(+) biosynthesis. Free Radical Research. 47: 699-709. PMID 23777333 DOI: 10.3109/10715762.2013.816420  0.84
2013 Liu D, Hakimi B, Volny M, Rolfs J, Chen X, Turecek F, Chiu DT. Controlled generation of double emulsions in air. Analytical Chemistry. 85: 6190-4. PMID 23767768 DOI: 10.1021/ac400844p  1
2013 Lin HR, Wu CC, Wu YH, Hsu CW, Cheng ML, Chiu DT. Proteome-wide dysregulation by glucose-6-phosphate dehydrogenase (G6PD) reveals a novel protective role for G6PD in aflatoxin B₁-mediated cytotoxicity. Journal of Proteome Research. 12: 3434-48. PMID 23742107 DOI: 10.1021/pr4002959  0.8
2013 Schurr JM, Fujimoto BS, Huynh L, Chiu DT. A theory of macromolecular chemotaxis. The Journal of Physical Chemistry. B. 117: 7626-52. PMID 23656252 DOI: 10.1021/jp302587d  1
2013 Wiener Z, Shapiro NI, Chiu DT, Grossman SA. The prevalence of psychiatric disease in emergency department patients with unexplained syncope. Internal and Emergency Medicine. 8: 427-30. PMID 23645509 DOI: 10.1007/s11739-013-0946-6  0.4
2013 Yang HC, Chen TL, Wu YH, Cheng KP, Lin YH, Cheng ML, Ho HY, Lo SJ, Chiu DT. Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans. Cell Death & Disease. 4: e616. PMID 23640458 DOI: 10.1038/cddis.2013.132  0.8
2013 Ye F, Smith PB, Wu C, Chiu DT. Ultrasensitive detection of proteins on Western blots with semiconducting polymer dots. Macromolecular Rapid Communications. 34: 785-90. PMID 23637077 DOI: 10.1002/marc.201200809  1
2013 Neupane B, Chen F, Sun W, Chiu DT, Wang G. Tuning donut profile for spatial resolution in stimulated emission depletion microscopy. The Review of Scientific Instruments. 84: 043701. PMID 23635197 DOI: 10.1063/1.4799665  1
2013 Sun W, Ye F, Gallina ME, Yu J, Wu C, Chiu DT. Lyophilization of semiconducting polymer dot bioconjugates. Analytical Chemistry. 85: 4316-20. PMID 23600767 DOI: 10.1021/ac4007123  1
2013 Zeigler MB, Chiu DT. Single-cell nanosurgery. Methods in Molecular Biology (Clifton, N.J.). 991: 139-48. PMID 23546666 DOI: 10.1007/978-1-62703-336-7_14  1
2013 Schneider T, Kreutz J, Chiu DT. The potential impact of droplet microfluidics in biology. Analytical Chemistry. 85: 3476-82. PMID 23495853 DOI: 10.1021/ac400257c  1
2013 Sgro AE, Bajjalieh SM, Chiu DT. Single-axonal organelle analysis method reveals new protein-motor associations. Acs Chemical Neuroscience. 4: 277-84. PMID 23421679 DOI: 10.1021/cn300136y  1
2013 Zhao M, Schiro PG, Kuo JS, Koehler KM, Sabath DE, Popov V, Feng Q, Chiu DT. An automated high-throughput counting method for screening circulating tumor cells in peripheral blood. Analytical Chemistry. 85: 2465-71. PMID 23387387 DOI: 10.1021/ac400193b  1
2013 Wu C, Chiu DT. Highly fluorescent semiconducting polymer dots for biology and medicine. Angewandte Chemie (International Ed. in English). 52: 3086-109. PMID 23307291 DOI: 10.1002/anie.201205133  1
2013 Rong Y, Wu C, Yu J, Zhang X, Ye F, Zeigler M, Gallina ME, Wu IC, Zhang Y, Chan YH, Sun W, Uvdal K, Chiu DT. Multicolor fluorescent semiconducting polymer dots with narrow emissions and high brightness. Acs Nano. 7: 376-84. PMID 23282278 DOI: 10.1021/nn304376z  1
2013 Ho HY, Cheng ML, Shiao MS, Chiu DT. Characterization of global metabolic responses of glucose-6-phosphate dehydrogenase-deficient hepatoma cells to diamide-induced oxidative stress. Free Radical Biology & Medicine. 54: 71-84. PMID 23142419 DOI: 10.1016/j.freeradbiomed.2012.10.557  0.8
2013 Sun W, Yu J, Ye F, Rong Y, Chiu DT. Highly fluorescent semiconducting polymer dots for single-molecule imaging and biosensing Proceedings of Spie - the International Society For Optical Engineering. 8812. DOI: 10.1117/12.2028187  1
2013 Zhang X, Yu J, Rong Y, Ye F, Chiu DT, Uvdal K. High-intensity near-IR fluorescence in semiconducting polymer dots achieved by cascade FRET strategy Chemical Science. 4: 2143-2151. DOI: 10.1039/c3sc50222h  1
2012 Gadd JC, Fujimoto BS, Bajjalieh SM, Chiu DT. Single-molecule fluorescence quantification with a photobleached internal standard. Analytical Chemistry. 84: 10522-5. PMID 23210507 DOI: 10.1021/ac303032m  1
2012 Chiu DT, Chung B. Discussion: Sensory reconstruction of a finger pulp defect using a dorsal homodigital island flap. Plastic and Reconstructive Surgery. 130: 1087-8. PMID 23096608 DOI: 10.1097/PRS.0b013e31826d2948  0.32
2012 Sun W, Hayden S, Jin Y, Rong Y, Yu J, Ye F, Chan YH, Zeigler M, Wu C, Chiu DT. A versatile method for generating semiconducting polymer dot nanocomposites. Nanoscale. 4: 7246-9. PMID 23072832 DOI: 10.1039/c2nr32055j  1
2012 Chan YH, Gallina ME, Zhang X, Wu IC, Jin Y, Sun W, Chiu DT. Reversible photoswitching of spiropyran-conjugated semiconducting polymer dots. Analytical Chemistry. 84: 9431-8. PMID 23033991 DOI: 10.1021/ac302245t  1
2012 Anand RK, Chiu DT. Analytical tools for characterizing heterogeneity in organelle content. Current Opinion in Chemical Biology. 16: 391-9. PMID 22694875 DOI: 10.1016/j.cbpa.2012.05.187  1
2012 Yu J, Wu C, Zhang X, Ye F, Gallina ME, Rong Y, Wu IC, Sun W, Chan YH, Chiu DT. Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging. Advanced Materials (Deerfield Beach, Fla.). 24: 3498-504. PMID 22684783 DOI: 10.1002/adma.201201245  1
2012 Zhang X, Yu J, Wu C, Jin Y, Rong Y, Ye F, Chiu DT. Importance of having low-density functional groups for generating high-performance semiconducting polymer dots. Acs Nano. 6: 5429-39. PMID 22607220 DOI: 10.1021/nn301308w  1
2012 Schiro PG, Gadd JC, Yen GS, Chiu DT. High-throughput fluorescence-activated nanoscale subcellular sorter with single-molecule sensitivity. The Journal of Physical Chemistry. B. 116: 10490-5. PMID 22574902 DOI: 10.1021/jp3019233  1
2012 Chan YH, Ye F, Gallina ME, Zhang X, Jin Y, Wu IC, Chiu DT. Hybrid semiconducting polymer dot-quantum dot with narrow-band emission, near-infrared fluorescence, and high brightness. Journal of the American Chemical Society. 134: 7309-12. PMID 22515545 DOI: 10.1021/ja3022973  1
2012 Gansen A, Herrick AM, Dimov IK, Lee LP, Chiu DT. Digital LAMP in a sample self-digitization (SD) chip. Lab On a Chip. 12: 2247-54. PMID 22399016 DOI: 10.1039/c2lc21247a  1
2012 Schiro PG, Zhao M, Kuo JS, Koehler KM, Sabath DE, Chiu DT. Sensitive and high-throughput isolation of rare cells from peripheral blood with ensemble-decision aliquot ranking. Angewandte Chemie (International Ed. in English). 51: 4618-22. PMID 22359315 DOI: 10.1002/anie.201108695  1
2012 Jin Y, Ye F, Wu C, Chan YH, Chiu DT. Generation of functionalized and robust semiconducting polymer dots with polyelectrolytes. Chemical Communications (Cambridge, England). 48: 3161-3. PMID 22349364 DOI: 10.1039/c2cc17703j  1
2012 Ye F, Wu C, Jin Y, Wang M, Chan YH, Yu J, Sun W, Hayden S, Chiu DT. A compact and highly fluorescent orange-emitting polymer dot for specific subcellular imaging. Chemical Communications (Cambridge, England). 48: 1778-80. PMID 22218705 DOI: 10.1039/c2cc16486h  1
2012 Gadd JC, Budzinski KL, Chan YH, Ye F, Chiu DT. Probing the interior of synaptic vesicles with internalized nanoparticles Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8232. DOI: 10.1117/12.905091  1
2011 Mutch SA, Gadd JC, Fujimoto BS, Kensel-Hammes P, Schiro PG, Bajjalieh SM, Chiu DT. Determining the number of specific proteins in cellular compartments by quantitative microscopy. Nature Protocols. 6: 1953-68. PMID 22094731 DOI: 10.1038/nprot.2011.414  1
2011 Chen YC, Chen CM, Liu JL, Chen ST, Cheng ML, Chiu DT. Oxidative markers in spontaneous intracerebral hemorrhage: leukocyte 8-hydroxy-2'-deoxyguanosine as an independent predictor of the 30-day outcome. Journal of Neurosurgery. 115: 1184-90. PMID 21962000 DOI: 10.3171/2011.7.JNS11718  0.84
2011 Budzinski KL, Zeigler M, Fujimoto BS, Bajjalieh SM, Chiu DT. Measurements of the acidification kinetics of single SynaptopHluorin vesicles. Biophysical Journal. 101: 1580-9. PMID 21961583 DOI: 10.1016/j.bpj.2011.08.032  1
2011 Burnham DR, Schneider T, Chiu DT. Effects of aliasing on the fidelity of a two dimensional array of foci generated with a kinoform. Optics Express. 19: 17121-6. PMID 21935073 DOI: 10.1364/OE.19.017121  1
2011 Cheng ML, Shiao MS, Chiu DT, Weng SF, Tang HY, Ho HY. Biochemical disorders associated with antiproliferative effect of dehydroepiandrosterone in hepatoma cells as revealed by LC-based metabolomics. Biochemical Pharmacology. 82: 1549-61. PMID 21843511 DOI: 10.1016/j.bcp.2011.07.104  0.84
2011 Chen KH, Cheng ML, Jing YH, Chiu DT, Shiao MS, Chen JK. Resveratrol ameliorates metabolic disorders and muscle wasting in streptozotocin-induced diabetic rats. American Journal of Physiology. Endocrinology and Metabolism. 301: E853-63. PMID 21791624 DOI: 10.1152/ajpendo.00048.2011  0.84
2011 Kuo JS, Chiu DT. Disposable microfluidic substrates: transitioning from the research laboratory into the clinic. Lab On a Chip. 11: 2656-65. PMID 21727966 DOI: 10.1039/c1lc20125e  1
2011 Pu LL, Chiu DT, Wei FC. The second world congress for plastic surgeons of Chinese descent. Plastic and Reconstructive Surgery. 128: 315-8. PMID 21701350 DOI: 10.1097/PRS.0b013e318217438a  0.4
2011 Budzinski KL, Sgro AE, Fujimoto BS, Gadd JC, Shuart NG, Gonen T, Bajjaleih SM, Chiu DT. Synaptosomes as a platform for loading nanoparticles into synaptic vesicles. Acs Chemical Neuroscience. 2: 236-241. PMID 21666849 DOI: 10.1021/cn200009n  1
2011 Zeigler MB, Allen PB, Chiu DT. Probing rotational viscosity in synaptic vesicles. Biophysical Journal. 100: 2846-51. PMID 21641331 DOI: 10.1016/j.bpj.2011.04.042  1
2011 Schneider T, Burnham DR, VanOrden J, Chiu DT. Systematic investigation of droplet generation at T-junctions. Lab On a Chip. 11: 2055-9. PMID 21589961 DOI: 10.1039/c1lc20259f  1
2011 Ye F, Wu C, Jin Y, Chan YH, Zhang X, Chiu DT. Ratiometric temperature sensing with semiconducting polymer dots. Journal of the American Chemical Society. 133: 8146-9. PMID 21548583 DOI: 10.1021/ja202945g  1
2011 Sgro AE, Nowak AL, Austin NS, Custer KL, Allen PB, Chiu DT, Bajjalieh SM. A high-throughput method for generating uniform microislands for autaptic neuronal cultures. Journal of Neuroscience Methods. 198: 230-5. PMID 21515305 DOI: 10.1016/j.jneumeth.2011.04.012  1
2011 Kuo JS, Chiu DT. Controlling mass transport in microfluidic devices. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 4: 275-96. PMID 21456968 DOI: 10.1146/annurev-anchem-061010-113926  1
2011 Wu C, Hansen SJ, Hou Q, Yu J, Zeigler M, Jin Y, Burnham DR, McNeill JD, Olson JM, Chiu DT. Design of highly emissive polymer dot bioconjugates for in vivo tumor targeting. Angewandte Chemie (International Ed. in English). 50: 3430-4. PMID 21381164 DOI: 10.1002/anie.201007461  1
2011 Chiu DT, Lee J. Autogenic heterotopic vascularized proximal interphalangeal joint transplantation in children. Microsurgery. 31: 198-204. PMID 21374712 DOI: 10.1002/micr.20861  0.96
2011 Jin Y, Ye F, Zeigler M, Wu C, Chiu DT. Near-infrared fluorescent dye-doped semiconducting polymer dots. Acs Nano. 5: 1468-75. PMID 21280613 DOI: 10.1021/nn103304m  1
2011 Mutch SA, Kensel-Hammes P, Gadd JC, Fujimoto BS, Allen RW, Schiro PG, Lorenz RM, Kuyper CL, Kuo JS, Bajjalieh SM, Chiu DT. Protein quantification at the single vesicle level reveals that a subset of synaptic vesicle proteins are trafficked with high precision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1461-70. PMID 21273430 DOI: 10.1523/JNEUROSCI.3805-10.2011  1
2011 Chan YH, Wu C, Ye F, Jin Y, Smith PB, Chiu DT. Development of ultrabright semiconducting polymer dots for ratiometric pH sensing. Analytical Chemistry. 83: 1448-55. PMID 21244093 DOI: 10.1021/ac103140x  1
2011 Chan YH, Jin Y, Wu C, Chiu DT. Copper(II) and iron(II) ion sensing with semiconducting polymer dots. Chemical Communications (Cambridge, England). 47: 2820-2. PMID 21240410 DOI: 10.1039/c0cc04929h  1
2011 Yen GS, Fujimoto BS, Schneider T, Huynh DT, Jeffries GD, Chiu DT. A rapid and economical method for profiling feature heights during microfabrication. Lab On a Chip. 11: 974-7. PMID 21229183 DOI: 10.1039/c0lc00470g  1
2011 Yang HC, Cheng ML, Ho HY, Chiu DT. The microbicidal and cytoregulatory roles of NADPH oxidases. Microbes and Infection / Institut Pasteur. 13: 109-20. PMID 20971207 DOI: 10.1016/j.micinf.2010.10.008  0.84
2011 Burnham DR, Schneider T, Chiu DT. Holographic optical traps and spectroscopic detection for probing cellular releasates Optics Infobase Conference Papers 1
2010 Burnham DR, Schneider T, Chiu DT. Optical Trapping Enabled Parallel Delivery of Biological Stimuli with High Spatial and Temporal Resolution. Proceedings of Spie--the International Society For Optical Engineering. 7762: 77621T. PMID 24465114 DOI: 10.1117/12.862519  1
2010 Gregersen KA, Hill ZB, Gadd JC, Fujimoto BS, Maly DJ, Chiu DT. Intracellular delivery of bioactive molecules using light-addressable nanocapsules. Acs Nano. 4: 7603-11. PMID 21117640 DOI: 10.1021/nn102345f  1
2010 Jeffries GD, Lorenz RM, Chiu DT. Ultrasensitive and high-throughput fluorescence analysis of droplet contents with orthogonal line confocal excitation. Analytical Chemistry. 82: 9948-54. PMID 21062029 DOI: 10.1021/ac102173m  1
2010 Wu C, Jin Y, Schneider T, Burnham DR, Smith PB, Chiu DT. Ultrabright and bioorthogonal labeling of cellular targets using semiconducting polymer dots and click chemistry. Angewandte Chemie (International Ed. in English). 49: 9436-40. PMID 20979060 DOI: 10.1002/anie.201004260  1
2010 Wu C, Schneider T, Zeigler M, Yu J, Schiro PG, Burnham DR, McNeill JD, Chiu DT. Bioconjugation of ultrabright semiconducting polymer dots for specific cellular targeting. Journal of the American Chemical Society. 132: 15410-7. PMID 20929226 DOI: 10.1021/ja107196s  1
2010 Cohen DE, Schneider T, Wang M, Chiu DT. Self-digitization of sample volumes. Analytical Chemistry. 82: 5707-17. PMID 20550137 DOI: 10.1021/ac100713u  1
2010 Sgro AE, Chiu DT. Droplet freezing, docking, and the exchange of immiscible phase and surfactant around frozen droplets. Lab On a Chip. 10: 1873-7. PMID 20467690 DOI: 10.1039/c001108h  1
2010 Lin CJ, Ho HY, Cheng ML, You TH, Cheng TH, Yu JS, Chiu DT. Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis. Free Radical Biology & Medicine. 49: 361-73. PMID 20420899 DOI: 10.1016/j.freeradbiomed.2010.04.019  0.8
2010 Chiu DT. Interfacing droplet microfluidics with chemical separation for cellular analysis. Analytical and Bioanalytical Chemistry. 397: 3179-83. PMID 20383695 DOI: 10.1007/s00216-010-3686-8  1
2010 Kuo JS, Zhao Y, Schiro PG, Ng L, Lim DS, Shelby JP, Chiu DT. Deformability considerations in filtration of biological cells. Lab On a Chip. 10: 837-42. PMID 20379567 DOI: 10.1039/b922301k  1
2010 Milne G, Zhao Y, Chiu DT. High-precision measurement and analysis of colloidal monolayers. Analytical Chemistry. 82: 3943-9. PMID 20353161 DOI: 10.1021/ac902722d  1
2010 Smith PB, Dendramis KA, Chiu DT. Investigating lyophilization of lipid nanocapsules with fluorescence correlation spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 10218-22. PMID 20302335 DOI: 10.1021/la1003808  1
2010 Allen PB, Milne G, Doepker BR, Chiu DT. Pressure-driven laminar flow switching for rapid exchange of solution environment around surface adhered biological particles. Lab On a Chip. 10: 727-33. PMID 20221560 DOI: 10.1039/b919639k  1
2010 Hurtig J, Chiu DT, Onfelt B. Intercellular nanotubes: insights from imaging studies and beyond. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2: 260-76. PMID 20166114 DOI: 10.1002/wnan.80  1
2010 Han MJ, Chiu DT, Koc EC. Regulation of mitochondrial ribosomal protein S29 (MRPS29) expression by a 5'-upstream open reading frame. Mitochondrion. 10: 274-83. PMID 20079882 DOI: 10.1016/j.mito.2009.12.150  1
2010 Lorenz RM, Chiu DT. Ultrasensitive Analysis of Individual Cells via Droplet Microfluidics Chemical Cytometry: Ultrasensitive Analysis of Single Cells. 143-157. DOI: 10.1002/9783527629640.ch9  1
2009 Zhao Y, Shapiro D, McGloin D, Chiu DT, Marchesini S. Direct observation of the transfer of orbital angular momentum to metal particles from a focused circularly polarized Gaussian beam. Optics Express. 17: 23316-22. PMID 20052258 DOI: 10.1364/OE.17.023316  1
2009 Colen KL, Choi M, Chiu DT. Nerve grafts and conduits. Plastic and Reconstructive Surgery. 124: e386-94. PMID 19952706 DOI: 10.1097/PRS.0b013e3181bf8430  0.32
2009 Jeffries GD, Milne G, Zhao Y, Lopez-Mariscal C, Chiu DT. Optofluidic generation of Laguerre-Gaussian beams. Optics Express. 17: 17555-62. PMID 19907539 DOI: 10.1364/OE.17.017555  1
2009 Budzinski KL, Allen RW, Fujimoto BS, Kensel-Hammes P, Belnap DM, Bajjalieh SM, Chiu DT. Large structural change in isolated synaptic vesicles upon loading with neurotransmitter. Biophysical Journal. 97: 2577-84. PMID 19883601 DOI: 10.1016/j.bpj.2009.08.032  1
2009 Dendramis KA, Chiu DT. Laser photolysis of dye-sensitized nanocapsules occurs via a photothermal pathway. Journal of the American Chemical Society. 131: 16771-8. PMID 19874014 DOI: 10.1021/ja904976r  1
2009 Zeigler MB, Chiu DT. Laser selection significantly affects cell viability following single-cell nanosurgery. Photochemistry and Photobiology. 85: 1218-24. PMID 19558419 DOI: 10.1111/j.1751-1097.2009.00581.x  1
2009 Ho HY, Cheng ML, Weng SF, Leu YL, Chiu DT. Antiviral effect of epigallocatechin gallate on enterovirus 71. Journal of Agricultural and Food Chemistry. 57: 6140-7. PMID 19537794 DOI: 10.1021/jf901128u  0.8
2009 Kuo JS, Zhao Y, Ng L, Yen GS, Lorenz RM, Lim DS, Chiu DT. Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices. Lab On a Chip. 9: 1951-6. PMID 19532971 DOI: 10.1039/b902124h  1
2009 Chiu DT, Lorenz RM, Jeffries GD. Droplets for ultrasmall-volume analysis. Analytical Chemistry. 81: 5111-8. PMID 19507850 DOI: 10.1021/ac900306q  1
2009 Gao LP, Cheng ML, Chou HJ, Yang YH, Ho HY, Chiu DT. Ineffective GSH regeneration enhances G6PD-knockdown Hep G2 cell sensitivity to diamide-induced oxidative damage. Free Radical Biology & Medicine. 47: 529-35. PMID 19497363 DOI: 10.1016/j.freeradbiomed.2009.05.029  0.84
2009 Allen PB, Doepker BR, Chiu DT. High-throughput capillary-electrophoresis analysis of the contents of a single mitochondria. Analytical Chemistry. 81: 3784-91. PMID 19344146 DOI: 10.1021/ac900099y  1
2009 Kuo JS, Ng L, Yen GS, Lorenz RM, Schiro PG, Edgar JS, Zhao Y, Lim DS, Allen PB, Jeffries GD, Chiu DT. A new USP Class VI-compliant substrate for manufacturing disposable microfluidic devices. Lab On a Chip. 9: 870-6. PMID 19294296 DOI: 10.1039/b818873d  1
2009 Wu YH, Cheng ML, Ho HY, Chiu DT, Wang TC. Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts. Journal of Biomedical Science. 16: 18. PMID 19272180 DOI: 10.1186/1423-0127-16-18  0.84
2009 Chiu DT, Lorenz RM. Chemistry and biology in femtoliter and picoliter volume droplets. Accounts of Chemical Research. 42: 649-58. PMID 19260732 DOI: 10.1021/ar8002464  1
2009 Cheng ML, Chen CM, Ho HY, Li JM, Chiu DT. Effect of acute myocardial infarction on erythrocytic glutathione peroxidase 1 activity and plasma vitamin e levels. The American Journal of Cardiology. 103: 471-5. PMID 19195504 DOI: 10.1016/j.amjcard.2008.09.104  0.8
2009 Edgar JS, Milne G, Zhao Y, Pabbati CP, Lim DS, Chiu DT. Compartmentalization of chemically separated components into droplets. Angewandte Chemie (International Ed. in English). 48: 2719-22. PMID 19142923 DOI: 10.1002/anie.200805396  1
2009 Zhao Y, Schiro PG, Kuo JS, Ng L, Chiu DT. Method for the accurate preparation of cell-spiking standards. Analytical Chemistry. 81: 1285-90. PMID 19115959 DOI: 10.1021/ac802250d  1
2009 Chen CM, Liu JL, Wu YR, Chen YC, Cheng HS, Cheng ML, Chiu DT. Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease. Neurobiology of Disease. 33: 429-35. PMID 19110057 DOI: 10.1016/j.nbd.2008.11.011  0.8
2009 Handayani S, Chiu DT, Tjitra E, Kuo JS, Lampah D, Kenangalem E, Renia L, Snounou G, Price RN, Anstey NM, Russell B. High deformability of Plasmodium vivax-infected red blood cells under microfluidic conditions. The Journal of Infectious Diseases. 199: 445-50. PMID 19090777 DOI: 10.1086/596048  1
2009 Chiu DT, Mutch SA, Fujimoto B, Gadd J, Bajjalieh SM. Quantitative TIRF microscopy for counting protein copy numbers in isolated Sub-cellular structures Microscopy and Microanalysis. 15: 72-73. DOI: 10.1017/S1431927609093593  1
2009 Chiu DT. Advances in the biological applications of optical micromanipulation Optics Infobase Conference Papers 1
2009 Chiu DT. Optical and microfluidic techniques for cellular analysis Optics Infobase Conference Papers 1
2008 Juo CG, Chiu DT, Shiao MS. Liquid chromatography-mass spectrometry in metabolite profiling. Biofactors (Oxford, England). 34: 159-69. PMID 19706981  0.84
2008 Ho HY, Cheng ML, Chen CM, Gu PW, Wang YL, Li JM, Chiu DT. Oxidative damage markers and antioxidants in patients with acute myocardial infarction and their clinical significance. Biofactors (Oxford, England). 34: 135-45. PMID 19706979  0.84
2008 Cheng ML, Ho HY, Lin JF, Chen YC, Chan EC, Chiu DT. Clinical relevance of plasma homocysteine levels in Taiwanese patients with coronary artery disease. Biofactors (Oxford, England). 34: 125-34. PMID 19706978  0.84
2008 Milne G, Jeffries GD, Chiu DT. Tunable generation of Bessel beams with a fluidic axicon. Applied Physics Letters. 92: 261101. PMID 19529839 DOI: 10.1063/1.2952833  1
2008 Zhao Y, Milne G, Edgar JS, Jeffries GD, McGloin D, Chiu DT. Quantitative force mapping of an optical vortex trap. Applied Physics Letters. 92: 161111-1611113. PMID 19479042 DOI: 10.1063/1.2912031  1
2008 Lorenz RM, Fiorini GS, Jeffries GD, Lim DS, He M, Chiu DT. Simultaneous generation of multiple aqueous droplets in a microfluidic device. Analytica Chimica Acta. 630: 124-30. PMID 19012823 DOI: 10.1016/j.aca.2008.10.009  1
2008 Ho HY, Cheng ML, Chiu HY, Weng SF, Chiu DT. Dehydroepiandrosterone induces growth arrest of hepatoma cells via alteration of mitochondrial gene expression and function. International Journal of Oncology. 33: 969-77. PMID 18949359  0.84
2008 Dendramis KA, Allen PB, Reid PJ, Chiu DT. Spectrally tunable uncaging of biological stimuli from nanocapsules. Chemical Communications (Cambridge, England). 4795-7. PMID 18830496 DOI: 10.1039/b806685j  1
2008 Ho HY, Cheng ML, Weng SF, Chang L, Yeh TT, Shih SR, Chiu DT. Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection. The Journal of General Virology. 89: 2080-9. PMID 18753216 DOI: 10.1099/vir.0.2008/001404-0  0.8
2008 Allen PB, Chiu DT. Calcium-assisted glass-to-glass bonding for fabrication of glass microfluidic devices. Analytical Chemistry. 80: 7153-7. PMID 18690699 DOI: 10.1021/ac801059h  1
2008 Allen PB, Sgro AE, Chao DL, Doepker BE, Scott Edgar J, Shen K, Chiu DT. Single-synapse ablation and long-term imaging in live C. elegans. Journal of Neuroscience Methods. 173: 20-6. PMID 18579213 DOI: 10.1016/j.jneumeth.2008.05.007  1
2008 Gadd JC, Kuyper CL, Fujimoto BS, Allen RW, Chiu DT. Sizing subcellular organelles and nanoparticles confined within aqueous droplets. Analytical Chemistry. 80: 3450-7. PMID 18363409 DOI: 10.1021/ac8000385  1
2008 Allen PB, Chiu DT. Alzheimer's disease protein Abeta1-42 does not disrupt isolated synaptic vesicles. Biochimica Et Biophysica Acta. 1782: 326-34. PMID 18339328 DOI: 10.1016/j.bbadis.2008.02.002  1
2008 Cheng ML, Chen CM, Gu PW, Ho HY, Chiu DT. Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction. Clinical Biochemistry. 41: 554-60. PMID 18314009 DOI: 10.1016/j.clinbiochem.2008.02.006  0.8
2008 Wu YH, Tseng CP, Cheng ML, Ho HY, Shih SR, Chiu DT. Glucose-6-phosphate dehydrogenase deficiency enhances human coronavirus 229E infection. The Journal of Infectious Diseases. 197: 812-6. PMID 18269318 DOI: 10.1086/528377  0.84
2007 Zhao Y, Fujimoto BS, Jeffries GD, Schiro PG, Chiu DT. Optical gradient flow focusing. Optics Express. 15: 6167-76. PMID 19546921 DOI: 10.1364/OE.15.006167  1
2007 Zhao Y, Edgar JS, Jeffries GD, McGloin D, Chiu DT. Spin-to-orbital angular momentum conversion in a strongly focused optical beam. Physical Review Letters. 99: 073901. PMID 17930896 DOI: 10.1103/PhysRevLett.99.073901  1
2007 Allen PB, Doepker BR, Chiu DT. Fourier transform capillary electrophoresis with laminar-flow gated pressure injection. Analytical Chemistry. 79: 6807-15. PMID 17676758 DOI: 10.1021/ac0710026  1
2007 Pan T, Fiorini GS, Chiu DT, Woolley AT. In-channel atom-transfer radical polymerization of thermoset polyester microfluidic devices for bioanalytical applications. Electrophoresis. 28: 2904-11. PMID 17640094 DOI: 10.1002/elps.200600817  1
2007 Ho HY, Cheng ML, Chiu DT. Glucose-6-phosphate dehydrogenase--from oxidative stress to cellular functions and degenerative diseases. Redox Report : Communications in Free Radical Research. 12: 109-18. PMID 17623517 DOI: 10.1179/135100007X200209  0.8
2007 Fiorini GS, Yim M, Jeffries GD, Schiro PG, Mutch SA, Lorenz RM, Chiu DT. Fabrication improvements for thermoset polyester (TPE) microfluidic devices. Lab On a Chip. 7: 923-6. PMID 17594014 DOI: 10.1039/b702548c  1
2007 Schiro PG, Kuyper CL, Chiu DT. Continuous-flow single-molecule CE with high detection efficiency. Electrophoresis. 28: 2430-8. PMID 17577880 DOI: 10.1002/elps.200600730  1
2007 Chen CM, Wu YR, Cheng ML, Liu JL, Lee YM, Lee PW, Soong BW, Chiu DT. Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington's disease patients. Biochemical and Biophysical Research Communications. 359: 335-40. PMID 17543886 DOI: 10.1016/j.bbrc.2007.05.093  0.84
2007 Sgro AE, Allen PB, Chiu DT. Thermoelectric manipulation of aqueous droplets in microfluidic devices. Analytical Chemistry. 79: 4845-51. PMID 17542555 DOI: 10.1021/ac062458a  1
2007 Ho HY, Cheng ML, Cheng PF, Chiu DT. Low oxygen tension alleviates oxidative damage and delays cellular senescence in G6PD-deficient cells. Free Radical Research. 41: 571-9. PMID 17454140 DOI: 10.1080/10715760601184819  0.8
2007 Jeffries GD, Kuo JS, Chiu DT. Controlled shrinkage and re-expansion of a single aqueous droplet inside an optical vortex trap. The Journal of Physical Chemistry. B. 111: 2806-12. PMID 17388431 DOI: 10.1021/jp068902v  1
2007 Jeffries GD, Edgar JS, Zhao Y, Shelby JP, Fong C, Chiu DT. Using polarization-shaped optical vortex traps for single-cell nanosurgery. Nano Letters. 7: 415-20. PMID 17298009 DOI: 10.1021/nl0626784  1
2007 Mutch SA, Fujimoto BS, Kuyper CL, Kuo JS, Bajjalieh SM, Chiu DT. Deconvolving single-molecule intensity distributions for quantitative microscopy measurements. Biophysical Journal. 92: 2926-43. PMID 17259276 DOI: 10.1529/biophysj.106.101428  1
2007 Jeffries GD, Kuo JS, Chiu DT. Dynamic modulation of chemical concentration in an aqueous droplet. Angewandte Chemie (International Ed. in English). 46: 1326-8. PMID 17203495 DOI: 10.1002/anie.200603072  1
2007 Lorenz RM, Edgar JS, Jeffries GD, Zhao Y, McGloin D, Chiu DT. Vortex-trap-induced fusion of femtoliter-volume aqueous droplets. Analytical Chemistry. 79: 224-8. PMID 17194143 DOI: 10.1021/ac061586w  1
2007 Chiu DT. Cellular manipulations in microvortices. Analytical and Bioanalytical Chemistry. 387: 17-20. PMID 16955264 DOI: 10.1007/s00216-006-0611-2  1
2007 McGloin D, Buchanan J, Burnham DR, Lorenz RM, Edgar JS, Jeffries GDM, Zhao Y, Chiu DT. Controlled fusion of femtoliter-volume aqueous droplets using holographic optical tweezers Conference On Lasers and Electro-Optics Europe - Technical Digest. DOI: 10.1109/CLEOE-IQEC.2007.4386646  1
2007 Cohen DE, Benedict JB, Morlan B, Chiu DT, Kahr B. Dyeing polymorphs: The MALDI host 2,5-dihydroxybenzoic acid Crystal Growth and Design. 7: 492-495. DOI: 10.1021/cg060887w  1
2007 Fiorini GS, Chiu DT. Nanoscale chemical analysis of individual subcellular compartments Chemical Analysis. 172: 119-140. DOI: 10.1002/9780470119501.ch6  1
2006 Kuyper CL, Fujimoto BS, Zhao Y, Schiro PG, Chiu DT. Accurate sizing of nanoparticles using confocal correlation spectroscopy. The Journal of Physical Chemistry. B. 110: 24433-41. PMID 17134198 DOI: 10.1021/jp064865w  1
2006 Edgar JS, Pabbati CP, Lorenz RM, He M, Fiorini GS, Chiu DT. Capillary electrophoresis separation in the presence of an immiscible boundary for droplet analysis. Analytical Chemistry. 78: 6948-54. PMID 17007519 DOI: 10.1021/ac0613131  1
2006 Ho HY, Cheng ML, Wang YH, Chiu DT. Flow cytometry for assessment of the efficacy of siRNA. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 1054-61. PMID 16998867 DOI: 10.1002/cyto.a.20324  0.8
2006 Lorenz RM, Edgar JS, Jeffries GD, Chiu DT. Microfluidic and optical systems for the on-demand generation and manipulation of single femtoliter-volume aqueous droplets. Analytical Chemistry. 78: 6433-9. PMID 16970318 DOI: 10.1021/ac060748l  1
2006 He M, Kuo JS, Chiu DT. Effects of ultrasmall orifices on the electrogeneration of femtoliter-volume aqueous droplets. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 6408-13. PMID 16800707 DOI: 10.1021/la060259g  1
2006 Sung YJ, Chiu DT, Ambron RT. Activation and retrograde transport of protein kinase G in rat nociceptive neurons after nerve injury and inflammation. Neuroscience. 141: 697-709. PMID 16730916 DOI: 10.1016/j.neuroscience.2006.04.033  0.32
2006 Wan GH, Lin KK, Tsai SC, Chiu DT. Decreased glucose-6-phosphate-dehydrogenase (G6PD) activity and risk of senile cataract in Taiwan. Ophthalmic Epidemiology. 13: 109-14. PMID 16581614 DOI: 10.1080/09286580500545709  0.8
2006 Kuyper CL, Kuo JS, Mutch SA, Chiu DT. Proton permeation into single vesicles occurs via a sequential two-step mechanism and is heterogeneous. Journal of the American Chemical Society. 128: 3233-40. PMID 16522104 DOI: 10.1021/ja057349c  1
2006 Ho HY, Wei TT, Cheng ML, Chiu DT. Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status. Journal of Agricultural and Food Chemistry. 54: 1638-45. PMID 16506813 DOI: 10.1021/jf0524372  0.8
2006 Kuyper CL, Budzinski KL, Lorenz RM, Chiu DT. Real-time sizing of nanoparticles in microfluidic channels using confocal correlation spectroscopy. Journal of the American Chemical Society. 128: 730-1. PMID 16417357 DOI: 10.1021/ja0569252  1
2005 Ho HY, Cheng ML, Chiu DT. G6PD--an old bottle with new wine. Chang Gung Medical Journal. 28: 606-12. PMID 16323551  0.8
2005 Sun B, Mutch SA, Lorenz RM, Chiu DT. Layered polyelectrolyte-silica coating for nanocapsules. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 10763-9. PMID 16262349 DOI: 10.1021/la0513297  1
2005 Pihl J, Karlsson M, Chiu DT. Microfluidic technologies in drug discovery. Drug Discovery Today. 10: 1377-83. PMID 16253876 DOI: 10.1016/S1359-6446(05)03571-3  1
2005 Tseng CP, Huang CL, Chong KY, Hung IJ, Chiu DT. Rapid detection of glucose-6-phosphate dehydrogenase gene mutations by denaturing high-performance liquid chromatography. Clinical Biochemistry. 38: 973-80. PMID 16137669 DOI: 10.1016/j.clinbiochem.2005.07.015  0.6
2005 Sun B, Chiu DT. Determination of the encapsulation efficiency of individual vesicles using single-vesicle photolysis and confocal single-molecule detection. Analytical Chemistry. 77: 2770-6. PMID 15859592 DOI: 10.1021/ac048439n  1
2005 Shelby JP, Edgar JS, Chiu DT. Monitoring cell survival after extraction of a single subcellular organelle using optical trapping and pulsed-nitrogen laser ablation. Photochemistry and Photobiology. 81: 994-1001. PMID 15850426 DOI: 10.1562/2005-02-02-RA-431  1
2005 Fiorini GS, Chiu DT. Disposable microfluidic devices: fabrication, function, and application. Biotechniques. 38: 429-46. PMID 15786809  1
2005 He M, Edgar JS, Jeffries GD, Lorenz RM, Shelby JP, Chiu DT. Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets. Analytical Chemistry. 77: 1539-44. PMID 15762555 DOI: 10.1021/ac0480850  1
2005 Cheng ML, Ho HY, Tseng HC, Lee CH, Shih LY, Chiu DT. Antioxidant deficit and enhanced susceptibility to oxidative damage in individuals with different forms of alpha-thalassaemia. British Journal of Haematology. 128: 119-27. PMID 15606558 DOI: 10.1111/j.1365-2141.2004.05257.x  0.84
2005 He M, Kuo JS, Chiu DT. Electro-generation of single femtoliter- and picoliter-volume aqueous droplets in microfluidic systems Applied Physics Letters. 87. DOI: 10.1063/1.1997280  1
2005 Kuyper CL, Jeffries GDM, Lorenz RM, Chiu DT. Single-Molecule Detection and Manipulation in Nanotechnology and Biology Nanofabrication Towards Biomedical Applications: Techniques, Tools, Applications, and Impact. 197-225. DOI: 10.1002/3527603476.ch8  1
2005 Shelby JP, Lim DSW, Kuo JS, Chiu DT. The generation, characterization, and application of microvortices in microfluidic systems Proceedings of the 3rd International Conference On Microchannels and Minichannels, 2005. 203-210.  1
2004 Sun B, Chiu DT. Synthesis, loading, and application of individual nanocapsules for probing single-cell signaling. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 4614-20. PMID 15969173 DOI: 10.1021/la0364340  1
2004 Kuo JS, Kuyper CL, Allen PB, Fiorini GS, Chiu DT. High-power blue/UV light-emitting diodes as excitation sources for sensitive detection. Electrophoresis. 25: 3796-804. PMID 15565689 DOI: 10.1002/elps.200406118  1
2004 Sun B, Lim DS, Kuo JS, Kuyper CL, Chiu DT. Fast initiation of chemical reactions with laser-induced breakdown of a nanoscale partition. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 9437-40. PMID 15491172 DOI: 10.1021/la048444m  1
2004 Liou JD, Chu DC, Cheng PJ, Chang SD, Sun CF, Wu YC, Liou WY, Chiu DT. Human chromosome 21-specific DNA markers are useful in prenatal detection of Down syndrome. Annals of Clinical and Laboratory Science. 34: 319-23. PMID 15487707  0.8
2004 Hsu YP, Chen RJ, Fang JF, Lin BC, Huang TL, Cheng ML, Chiu DT, Tsay PK. Increased susceptibility to oxidant injury in hepatocytes from rats with intra-abdominal hypertension. The Journal of Trauma. 57: 569-75. PMID 15454804  0.84
2004 Fiorini GS, Lorenz RM, Kuo JS, Chiu DT. Rapid prototyping of thermoset polyester microfluidic devices. Analytical Chemistry. 76: 4697-704. PMID 15307779 DOI: 10.1021/ac0498922  1
2004 Chiu DT, Smahel J, Chen L, Meyer V. Neurotropism revisited. Neurological Research. 26: 381-7. PMID 15198863 DOI: 10.1179/016164104225013815  0.84
2004 Shelby JP, Chiu DT. Controlled rotation of biological micro- and nano-particles in microvortices. Lab On a Chip. 4: 168-70. PMID 15159772 DOI: 10.1039/b402479f  1
2004 Shelby JP, Mutch SA, Chiu DT. Direct manipulation and observation of the rotational motion of single optically trapped microparticles and biological cells in microvortices. Analytical Chemistry. 76: 2492-7. PMID 15117188 DOI: 10.1021/ac035531v  1
2004 Campos L, Meng Z, Hu G, Chiu DT, Ambron RT, Martin JH. Engineering novel spinal circuits to promote recovery after spinal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2090-101. PMID 14999060 DOI: 10.1523/JNEUROSCI.5526-03.2004  0.32
2004 He M, Sun C, Chiu DT. Concentrating solutes and nanoparticles within individual aqueous microdroplets. Analytical Chemistry. 76: 1222-7. PMID 14987074 DOI: 10.1021/ac035196a  0.8
2004 Cheng ML, Ho HY, Wu YH, Chiu DT. Glucose-6-phosphate dehydrogenase-deficient cells show an increased propensity for oxidant-induced senescence. Free Radical Biology & Medicine. 36: 580-91. PMID 14980702 DOI: 10.1016/j.freeradbiomed.2003.11.031  0.8
2004 Lim DS, Kuo JS, Chiu DT. Parametric investigation on the effect of channel topologies on electrophoretic separations. Journal of Chromatography. A. 1027: 237-44. PMID 14971508  1
2003 Fiorini GS, Jeffries GD, Lim DS, Kuyper CL, Chiu DT. Fabrication of thermoset polyester microfluidic devices and embossing masters using rapid prototyped polydimethylsiloxane molds. Lab On a Chip. 3: 158-63. PMID 15100767 DOI: 10.1039/b305074m  1
2003 Shelby JP, White J, Ganesan K, Rathod PK, Chiu DT. A microfluidic model for single-cell capillary obstruction by Plasmodium falciparum-infected erythrocytes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14618-22. PMID 14638939 DOI: 10.1073/pnas.2433968100  1
2003 Shelby JP, Lim DS, Kuo JS, Chiu DT. Microfluidic systems: high radial acceleration in microvortices. Nature. 425: 38. PMID 12955132 DOI: 10.1038/425038a  1
2003 Lundqvist A, Chiu DT, Orwar O. Electrophoretic separation and confocal laser-induced fluorescence detection at ultralow concentrations in constricted fused-silica capillaries. Electrophoresis. 24: 1737-44. PMID 12783450 DOI: 10.1002/elps.200305429  0.6
2003 Allen PB, Rodriguez I, Kuyper CL, Lorenz RM, Spicar-Mihalic P, Kuo JS, Chiu DT. Selective electroless and electrolytic deposition of metal for applications in microfluidics: fabrication of a microthermocouple. Analytical Chemistry. 75: 1578-83. PMID 12705588 DOI: 10.1021/ac020498i  1
2003 Shelby JP, Chiu DT. Mapping fast flows over micrometer-length scales using flow-tagging velocimetry and single-molecule detection. Analytical Chemistry. 75: 1387-92. PMID 12659200 DOI: 10.1021/ac026275+  1
2003 Sun B, Chiu DT. Spatially and temporally resolved delivery of stimuli to single cells. Journal of the American Chemical Society. 125: 3702-3. PMID 12656592 DOI: 10.1021/ja029942p  1
2003 Wu H, Odom TW, Chiu DT, Whitesides GM. Fabrication of complex three-dimensional microchannel systems in PDMS. Journal of the American Chemical Society. 125: 554-9. PMID 12517171 DOI: 10.1021/ja021045y  1
2002 Sinclair J, Pihl J, Olofsson J, Karlsson M, Jardemark K, Chiu DT, Orwar O. A cell-based bar code reader for high-throughput screening of ion channel-ligand interactions. Analytical Chemistry. 74: 6133-8. PMID 12510730  0.6
2001 Ismagilov RF, Rosmarin TD, Kenis JA, Chiu DT, Zhang W, Stone HA, Whitesides GM. Pressure-driven laminar flow in tangential microchannels: an elastomeric microfluidic switch. Analytical Chemistry. 73: 4682-7. PMID 11605847 DOI: 10.1021/ac010374q  1
2001 Chabinyc ML, Chiu DT, McDonald JC, Stroock AD, Christian JF, Karger AM, Whitesides GM. An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications. Analytical Chemistry. 73: 4491-8. PMID 11575798 DOI: 10.1021/ac010423z  1
2001 Wilson CF, Simpson GJ, Chiu DT, Strömberg A, Orwar O, Rodriguez N, Zare RN. Nanoengineered structures for holding and manipulating liposomes and cells. Analytical Chemistry. 73: 787-91. PMID 11248893 DOI: 10.1021/ac001020m  1
2001 Chiu DT, Pezzoli E, Wu H, Stroock AD, Whitesides GM. Using three-dimensional microfluidic networks for solving computationally hard problems. Proceedings of the National Academy of Sciences of the United States of America. 98: 2961-6. PMID 11248014 DOI: 10.1073/pnas.061014198  1
2000 Stroock AD, Weck M, Chiu DT, Huck WT, Kenis PJ, Ismagilov RF, Whitesides GM. Patterning electro-osmotic flow with patterned surface charge. Physical Review Letters. 84: 3314-7. PMID 11019078  1
2000 Anderson JR, Chiu DT, Jackman RJ, Cherniavskaya O, McDonald JC, Wu H, Whitesides SH, Whitesides GM. Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping. Analytical Chemistry. 72: 3158-64. PMID 10939381 DOI: 10.1021/ac9912294  1
2000 Chiu DT, Jeon NL, Huang S, Kane RS, Wargo CJ, Choi IS, Ingber DE, Whitesides GM. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proceedings of the National Academy of Sciences of the United States of America. 97: 2408-13. PMID 10681460 DOI: 10.1073/pnas.040562297  1
2000 McDonald JC, Duffy DC, Anderson JR, Chiu DT, Wu H, Schueller OJ, Whitesides GM. Fabrication of microfluidic systems in poly(dimethylsiloxane). Electrophoresis. 21: 27-40. PMID 10634468 DOI: 10.1002/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO;2-C  1
2000 Strömberg A, Ryttsén F, Chiu DT, Davidson M, Eriksson PS, Wilson CF, Orwar O, Zare RN. Manipulating the genetic identity and biochemical surface properties of individual cells with electric-field-induced fusion. Proceedings of the National Academy of Sciences of the United States of America. 97: 7-11. PMID 10618361 DOI: 10.1073/pnas.97.1.7  1
1999 Chiu DT, Wilson CF, Ryttsén F, Strömberg A, Farre C, Karlsson A, Nordholm S, Gaggar A, Modi BP, Moscho A, Garza-López RA, Orwar O, Zare RN. Chemical transformations in individual ultrasmall biomimetic containers. Science (New York, N.Y.). 283: 1892-5. PMID 10082457  0.96
1998 Lillard SJ, Chiu DT, Scheller RH, Zare RN, Rodríguez-Cruz SE, Williams ER, Orwar O, Sandberg M, Lundqvist JA. Separation and characterization of amines from individual atrial gland vesicles of Aplysia californica. Analytical Chemistry. 70: 3517-24. PMID 9737203  1
1998 Chiu DT, Zare RN. Assaying for peptides in individual Aplysia neurons with mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 95: 3338-40. PMID 9520363  0.96
1998 Chiu DT, Lillard SJ, Scheller RH, Zare RN, Rodriguez-Cruz SE, Williams ER, Orwar O, Sandberg M, Lundqvist JA. Probing single secretory vesicles with capillary electrophoresis. Science (New York, N.Y.). 279: 1190-3. PMID 9469805 DOI: 10.1126/science.279.5354.1190  1
1997 Chiu DT, Hsiao A, Gaggar A, Garza-López RA, Orwar O, Zare RN. Injection of ultrasmall samples and single molecules into tapered capillaries. Analytical Chemistry. 69: 1801-7. PMID 9164157  1
1996 Moscho A, Orwar O, Chiu DT, Modi BP, Zare RN. Rapid preparation of giant unilamellar vesicles. Proceedings of the National Academy of Sciences of the United States of America. 93: 11443-7. PMID 8876154  0.96
1994 Nie S, Chiu DT, Zare RN. Probing individual molecules with confocal fluorescence microscopy. Science (New York, N.Y.). 266: 1018-21. PMID 7973650  1
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