Cullen L. Schmid - Related publications

Affiliations: 
2011 Ohio State University, Columbus, Columbus, OH 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Gopalakrishnan L, Chatterjee O, Ravishankar N, Suresh S, Raju R, Mahadevan A, Prasad TSK. Opioid receptors signaling network. Journal of Cell Communication and Signaling. PMID 34724150 DOI: 10.1007/s12079-021-00653-z   
2021 Sharma KK, Cassell RJ, Meqbil YJ, Su H, Blaine AT, Cummins BR, Mores KL, Johnson DK, van Rijn RM, Altman RA. Modulating β-arrestin 2 recruitment at the δ- and μ-opioid receptors using peptidomimetic ligands. Rsc Medicinal Chemistry. 12: 1958-1967. PMID 34825191 DOI: 10.1039/d1md00025j   
2021 Wu LX, Dong YP, Zhu QM, Zhang B, Ai BL, Yan T, Zhang GH, Sun L. Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain. Bmc Cancer. 21: 1128. PMID 34670518 DOI: 10.1186/s12885-021-08850-0   
2021 Dodu JC, Moncayo RK, Damaj MI, Schlosburg JE, Akbarali HI, O'Brien LD, Kendall DA, Lu D, Lichtman AH. The CB Receptor Positive Allosteric Modulator, ZCZ011, Attenuates Naloxone-Precipitated Diarrhea and Weight Loss in Oxycodone-Dependent Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 34625464 DOI: 10.1124/jpet.121.000723   
2021 Liu S, Kang WJ, Abrimian A, Xu J, Cartegni L, Majumdar S, Hesketh P, Bekker A, Pan YX. Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, : Insight into Complex Mu Opioid Actions. Biomolecules. 11. PMID 34680158 DOI: 10.3390/biom11101525   
2021 Kong Q, Tian S, Ma C, Wang G, Zhang M. Cannabinoid Receptor Type 2 Agonist Reduces Morphine Tolerance via Mitogen Activated Protein Kinase Phosphatase Induction and Mitogen Activated Protein Kinase Dephosphorylation. Neuroscience. PMID 34774714 DOI: 10.1016/j.neuroscience.2021.11.007   
2021 Mehr-Un-Nisa, Munawar MA, Rankin D, Hruby VJ, Porreca F, Lee YS. C-terminal modified Enkephalin-like tetrapeptides with enhanced affinities at the kappa opioid receptor and monoamine transporters. Bioorganic & Medicinal Chemistry. 51: 116509. PMID 34798381 DOI: 10.1016/j.bmc.2021.116509   
2021 Zamora JC, Smith HR, Jennings EM, Chavera TS, Kotipalli V, Jay A, Husbands SM, Disney A, Berg KA, Clarke WP. Long-term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox. Pharmacology Research & Perspectives. 9: e00887. PMID 34713624 DOI: 10.1002/prp2.887   
2021 Zhang F, Chen X, Chen J, Xu Y, Li S, Guo Y, Pu X. Probing Allosteric Regulation Mechanism of W7.35 on Agonist-Induced Activity for μOR by Mutation Simulation. Journal of Chemical Information and Modeling. PMID 34779608 DOI: 10.1021/acs.jcim.1c00650   
2021 Yang Y, Wang Y, Zuo A, Li C, Wang W, Jiang W, Zhang X, Che X, Zhang Y, Wu W, Cen X, Wang H, Tian J. Synthesis, biological, and structural explorations of a series of μ-opioid receptor (MOR) agonists with high G protein signaling bias. European Journal of Medicinal Chemistry. 113986. PMID 34802839 DOI: 10.1016/j.ejmech.2021.113986   
2021 Mitra A, Sarkar A, Borics A. Universal Properties and Specificities of the β-Adrenergic Receptor-G Protein Complex Activation Mechanism Revealed by All-Atom Molecular Dynamics Simulations. International Journal of Molecular Sciences. 22. PMID 34638767 DOI: 10.3390/ijms221910423   
2021 Nozohouri S, Zhang Y, Albekairi TH, Vaidya B, Abbruscato TJ. . The Journal of Pharmacology and Experimental Therapeutics. PMID 34663677 DOI: 10.1124/jpet.121.000831   
2021 Mansour A, Nagi K, Dallaire P, Lukasheva V, Le Gouill C, Bouvier M, Pineyro G. Comprehensive Signaling Profiles Reveal Unsuspected Functional Selectivity of δ-Opioid Receptor Agonists and Allow the Identification of Ligands with the Greatest Potential for Inducing Cyclase Superactivation. Acs Pharmacology & Translational Science. 4: 1483-1498. PMID 34661070 DOI: 10.1021/acsptsci.1c00019   
2021 DiCello JJ, Carbone SE, Saito A, Pham V, Szymaszkiewicz A, Gondin AB, Alvi S, Marique K, Shenoy P, Veldhuis NA, Fichna J, Canals M, Christopoulos A, Valant C, Poole DP. Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gut motility disorders. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 34755545 DOI: 10.1152/ajpgi.00297.2021   
2021 García M, Llorente V, Garriga L, Christmann U, Rodríguez-Escrich S, Virgili M, Fernández B, Bordas M, Ayet E, Burgueño J, Pujol M, Dordal A, Portillo-Salido E, Gris G, Vela JM, et al. Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ Receptor Antagonists for the Treatment of Pain. Journal of Medicinal Chemistry. 64: 10139-10154. PMID 34236190 DOI: 10.1021/acs.jmedchem.1c00417   
2021 Garnelo Gómez B, Holzwart E, Shi C, Lozano-Durán R, Wolf S. Phosphorylation-dependent routing of RLP44 towards brassinosteroid or phytosulfokine signalling. Journal of Cell Science. 134. PMID 34569597 DOI: 10.1242/jcs.259134   
2021 Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, et al. Structure, function and pharmacology of human itch GPCRs. Nature. PMID 34789874 DOI: 10.1038/s41586-021-04126-6   
2021 Raïch I, Rivas-Santisteban R, Lillo A, Lillo J, Reyes-Resina I, Nadal X, Ferreiro-Vera C, de Medina VS, Majellaro M, Sotelo E, Navarro G, Franco R. Similarities and differences upon binding of naturally occurring Δ-tetrahydrocannabinol-derivatives to cannabinoid CB and CB receptors. Pharmacological Research. 174: 105970. PMID 34758399 DOI: 10.1016/j.phrs.2021.105970   
2021 Turner RC, Gatson BJ, Hernandez JA, Alexander AB, Aitken-Palmer C, Vigani A, Heard DJ. Sedation and Anesthesia of Galapagos (), Aldabra (), and African Spurred Tortoises (): A Retrospective Review (2009-2019). Animals : An Open Access Journal From Mdpi. 11. PMID 34679940 DOI: 10.3390/ani11102920   
2021 Wolf P, Mohr A, Gavins G, Behr V, Mörl K, Seitz O, Beck-Sickinger AG. Orthogonal Peptide-Templated Labeling Elucidates Lateral ET R/ET R Proximity and Reveals Altered Downstream Signaling. Chembiochem : a European Journal of Chemical Biology. PMID 34699123 DOI: 10.1002/cbic.202100340   
2021 Duan LL, Qiu XY, Wei SQ, Su HY, Bai FR, Traub RJ, Zhou Q, Cao DY. Spinal CCK contributes to somatic hyperalgesia induced by orofacial inflammation combined with stress in adult female rats. European Journal of Pharmacology. 174619. PMID 34748768 DOI: 10.1016/j.ejphar.2021.174619   
2021 Yan W, Fan L, Yu J, Liu R, Wang H, Tan L, Wang S, Cheng J. 2-Phenylcyclopropylmethylamine Derivatives as Dopamine D Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation. Journal of Medicinal Chemistry. PMID 34797051 DOI: 10.1021/acs.jmedchem.1c01327   
2021 Romantini N, Alam S, Dobitz S, Spillmann M, De Foresta M, Schibli R, Schertler GFX, Wennemers H, Deupi X, Behe M, Berger P. Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34810259 DOI: 10.1073/pnas.2108776118   
2021 Ding G, Li D, Sun Y, Chen K, Song D. -Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca/CaMKII/CREB Pathway. Journal of Healthcare Engineering. 2021: 3401654. PMID 34608407 DOI: 10.1155/2021/3401654   
2021 Matsushita Y, Manabe M, Kitagawa I, Higuchi M, Hosaka YZ, Kitamura N. Inhibition of transient receptor potential vanilloid type 1 through α adrenergic receptors at peripheral nerve terminals relieves pain. The Journal of Veterinary Medical Science. 83: 1570-1581. PMID 34470979 DOI: 10.1292/jvms.21-0429   
2021 Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, et al. Oxidative Metabolism as a Modulator of Kratom's Biological Actions. Journal of Medicinal Chemistry. PMID 34783240 DOI: 10.1021/acs.jmedchem.1c01111   
2021 Suresh M, Li B, Huang X, Korolowicz KE, Murreddu MG, Gudima SO, Menne S. Agonistic Activation of Cytosolic DNA Sensing Receptors in Woodchuck Hepatocyte Cultures and Liver for Inducing Antiviral Effects. Frontiers in Immunology. 12: 745802. PMID 34671360 DOI: 10.3389/fimmu.2021.745802   
2021 Faúndez-Parraguez M, Alarcón-Miranda C, Cho YH, Pessoa-Mahana H, Gallardo-Garrido C, Chung H, Faúndez M, Pessoa-Mahana D. New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists. International Journal of Molecular Sciences. 22. PMID 34681877 DOI: 10.3390/ijms222011212   
2021 Gao J, Yuan X, Zheng X, Zhao X, Wang T, Liang Q, Xiao C, Wang J, Li Q, Zhao X. Two-point immobilization of a conformation-specific beta-adrenoceptor for recognizing the receptor agonists or antagonists inspired by binding-induced DNA assembly. Biomaterials Science. PMID 34704989 DOI: 10.1039/d1bm01222c   
2021 O'Sullivan SE, Yates AS, Porter RK. The Peripheral Cannabinoid Receptor Type 1 (CB) as a Molecular Target for Modulating Body Weight in Man. Molecules (Basel, Switzerland). 26. PMID 34684760 DOI: 10.3390/molecules26206178   
2021 Luyao H, Luesch H, Uy M. GPCR Pharmacological Profiling of Aaptamine from the Philippine Sponge sp. Extends Its Therapeutic Potential for Noncommunicable Diseases. Molecules (Basel, Switzerland). 26. PMID 34577088 DOI: 10.3390/molecules26185618   
2021 Deodhar M, Turgeon J, Michaud V. Contribution of CYP2D6 Functional Activity to Oxycodone Efficacy in Pain Management: Genetic Polymorphisms, Phenoconversion, and Tissue-Selective Metabolism. Pharmaceutics. 13. PMID 34575542 DOI: 10.3390/pharmaceutics13091466   
2021 Horváth VB, Soltész-Katona E, Wisniewski É, Rajki A, Halász E, Enyedi B, Hunyady L, Tóth AD, Szanda G. Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB) Receptor. Frontiers in Endocrinology. 12: 740913. PMID 34745007 DOI: 10.3389/fendo.2021.740913   
2021 Rivera R, Williams NA, Kennedy GG, Sánchez-Pavón P, Chun J. Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line. Cell Biochemistry and Biophysics. 79: 619-627. PMID 34652685 DOI: 10.1007/s12013-021-01033-5   
2021 Howlett AC, Thomas BF, Huffman JW. The Spicy Story of Cannabimimetic Indoles. Molecules (Basel, Switzerland). 26. PMID 34684770 DOI: 10.3390/molecules26206190   
2021 Ishida A, Okabe Y, Matsushita T, Sekiguchi T, Nishio T, Komagata T, Iwaki M, Miyata H, Katagi J, Naganawa A, Maruyama T, Imagawa A. Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis. Bioorganic & Medicinal Chemistry. 49: 116424. PMID 34626901 DOI: 10.1016/j.bmc.2021.116424   
2021 Wang W, Bian J, Sun Y, Li Z. The new fate of internalized membrane receptors: Internalized activation. Pharmacology & Therapeutics. 108018. PMID 34626676 DOI: 10.1016/j.pharmthera.2021.108018   
2021 Pham N, Miller MD, Marty M. Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes. Chemical Research in Toxicology. 34: 2319-2330. PMID 34705446 DOI: 10.1021/acs.chemrestox.1c00205   
2021 Li YL, Li YX, Wang XP, Kang XL, Guo KQ, Dong DJ, Wang JX, Zhao XF. Identification and Functional Analysis of G Protein-Coupled Receptors in 20-Hydroxyecdysone Signaling From the Genome. Frontiers in Cell and Developmental Biology. 9: 753787. PMID 34765604 DOI: 10.3389/fcell.2021.753787   
2021 Fouad Shalaby MA, Abd El Latif HA, El Yamani M, Galal MA, Kamal S, Sindi I, Masaood R. Therapeutic activity of sarpogrelate and dopamine D receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes. Bmc Pharmacology & Toxicology. 22: 64. PMID 34702339 DOI: 10.1186/s40360-021-00526-6   
2021 Hinds CE, Owen BM, Hope DCD, Pickford P, Jones B, Tan TM, Minnion JS, Bloom SR. A glucagon analogue decreases body weight in mice via signalling in the liver. Scientific Reports. 11: 22577. PMID 34799628 DOI: 10.1038/s41598-021-01912-0   
2021 Tasma Z, Siow A, Harris PWR, Brimble MA, Hay DL, Walker CS. Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: implications for drug discovery. British Journal of Pharmacology. PMID 34612509 DOI: 10.1111/bph.15700   
2021 Cai X, Yao Y, Teng F, Li Y, Wu L, Yan W, Lin N. The role of P2X7 receptor in infection and metabolism: Based on inflammation and immunity. International Immunopharmacology. 101: 108297. PMID 34717202 DOI: 10.1016/j.intimp.2021.108297   
2021 Okita K, Kato K, Shigemoto Y, Sato N, Matsumoto T, Matsuda H. Effects of an Adenosine A Receptor Antagonist on Striatal Dopamine D2-Type Receptor Availability: A Randomized Control Study Using Positron Emission Tomography. Frontiers in Neuroscience. 15: 729153. PMID 34588952 DOI: 10.3389/fnins.2021.729153   
2021 Steindorf D, Loeuillet A, Bagnard D, Strand S, Schneider D. Increased stability of the TM helix oligomer abrogates the apoptotic activity of the human Fas receptor. Biochimica Et Biophysica Acta. Biomembranes. 1864: 183807. PMID 34662567 DOI: 10.1016/j.bbamem.2021.183807   
2021 Han J, Andreu V, Langreck C, Pekarskaya EA, Grinnell SG, Allain F, Magalong V, Pintar J, Kieffer BL, Harris AZ, Javitch JA, Hen R, Nautiyal KM. Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34593976 DOI: 10.1038/s41386-021-01192-2   
2021 Kimura Y, Takahata K, Shimazaki T, Kitamura S, Seki C, Ikoma Y, Ichise M, Kawamura K, Yamada M, Zhang MR, Higuchi M, Nishino I, Suhara T. Pharmacokinetic and pharmacodynamic assessment of histamine H receptor occupancy by enerisant: a human PET study with a novel H binding ligand, [C]TASP457. European Journal of Nuclear Medicine and Molecular Imaging. PMID 34651222 DOI: 10.1007/s00259-021-05571-1   
2021 Levick SP. Histamine receptors in heart failure. Heart Failure Reviews. PMID 34622365 DOI: 10.1007/s10741-021-10166-x   
2021 Denys IB, Gao J, Sutphen JC, Zaveri NT, Kapusta DR. Cardiovascular and renal effects of novel non-peptide nociceptin opioid peptide (NOP) receptor agonists. British Journal of Pharmacology. PMID 34705263 DOI: 10.1111/bph.15717   
2021 Brockett AT, Deng C, Shuster M, Perera S, DiMaggio D, Cheng M, Murkli S, Briken V, Roesch MR, Isaacs L. In Vitro and In Vivo Sequestration of Methamphetamine by a Sulfated Acyclic CB[n]-Type Receptor. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34613641 DOI: 10.1002/chem.202102919