Dan Rudolf Littman, MD, Ph.D. - Publications

Affiliations: 
2014- Microbiology Immunology NYU Langone Medical Center 

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ménager MM, Littman DR. Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell. PMID 26830877 DOI: 10.1016/j.cell.2015.12.036  0.72
2016 Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR. The maternal interleukin-17a pathway in mice promotes autismlike phenotypes in offspring. Science (New York, N.Y.). PMID 26822608 DOI: 10.1126/science.aad0314  0.72
2016 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Littman DR, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/nature16968  0.72
2015 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Littman DR, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/nature16193  0.72
2015 Sano T, Huang W, Hall JA, Yang Y, Chen A, Gavzy SJ, Lee JY, Ziel JW, Miraldi ER, Domingos AI, Bonneau R, Littman DR. An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses. Cell. PMID 26411290 DOI: 10.1016/j.cell.2015.08.061  0.72
2015 Littman DR. Releasing the Brakes on Cancer Immunotherapy. Cell. 162: 1186-90. PMID 26359975 DOI: 10.1016/j.cell.2015.08.038  0.72
2015 Scher JU, Littman DR, Abramson SB. Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26331579 DOI: 10.1002/art.39259  0.72
2015 Pitt LA, Tikhonova AN, Hu H, Trimarchi T, King B, Gong Y, Sanchez-Martin M, Tsirigos A, Littman DR, Ferrando AA, Morrison SJ, Fooksman DR, Aifantis I, Schwab SR. CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance. Cancer Cell. 27: 755-68. PMID 26058075 DOI: 10.1016/j.ccell.2015.05.002  0.72
2015 Sellars M, Huh JR, Day K, Issuree PD, Galan C, Gobeil S, Absher D, Green MR, Littman DR. Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages. Nature Immunology. 16: 746-54. PMID 26030024 DOI: 10.1038/ni.3198  0.72
2015 Longman RS, Littman DR. The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. Current Opinion in Rheumatology. 27: 381-7. PMID 26002030 DOI: 10.1097/BOR.0000000000000190  0.72
2015 Kurtz ZD, Müller CL, Miraldi ER, Littman DR, Blaser MJ, Bonneau RA. Sparse and compositionally robust inference of microbial ecological networks. Plos Computational Biology. 11: e1004226. PMID 25950956 DOI: 10.1371/journal.pcbi.1004226  0.72
2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, ... ... Littman DR, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 607-17. PMID 25918343 DOI: 10.1084/jem.20132378  0.72
2015 Santori FR, Huang P, van de Pavert SA, Douglass EF, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, ... ... Littman DR, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97. PMID 25651181 DOI: 10.1016/j.cmet.2015.01.004  0.72
2014 Ravel J, Blaser MJ, Braun J, Brown E, Bushman FD, Chang EB, Davies J, Dewey KG, Dinan T, Dominguez-Bello M, Erdman SE, Finlay BB, Garrett WS, Huffnagle GB, Huttenhower C, ... ... Littman DR, et al. Human microbiome science: Vision for the future, Bethesda, MD, July 24 to 26, 2013 Microbiome. 2.  0.72
2011 Zhdanova O, Srivastava S, Di L, Li Z, Tchelebi L, Dworkin S, Johnstone DB, Zavadil J, Chong MM, Littman DR, Holzman LB, Barisoni L, Skolnik EY. The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy. Kidney International. 80: 719-30. PMID 21544061 DOI: 10.1038/ki.2011.122  0.72
2011 Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, ... ... Littman DR, et al. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature. 472: 486-90. PMID 21441909 DOI: 10.1038/nature09978  0.72
2011 Collins A, Hewitt SL, Chaumeil J, Sellars M, Micsinai M, Allinne J, Parisi F, Nora EP, Bolland DJ, Corcoran AE, Kluger Y, Bosselut R, Ellmeier W, Chong MM, Littman DR, et al. RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation. Immunity. 34: 303-14. PMID 21435585 DOI: 10.1016/j.immuni.2011.03.004  0.72
2011 Cruz-Orengo L, Holman DW, Dorsey D, Zhou L, Zhang P, Wright M, McCandless EE, Patel JR, Luker GD, Littman DR, Russell JH, Klein RS. CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. The Journal of Experimental Medicine. 208: 327-39. PMID 21300915 DOI: 10.1084/jem.20102010  0.72
2011 Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, ... ... Littman DR, et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 471: 325-30. PMID 21297615 DOI: 10.1038/nature09830  0.72
2011 Ivanov II, Littman DR. Modulation of immune homeostasis by commensal bacteria. Current Opinion in Microbiology. 14: 106-14. PMID 21215684 DOI: 10.1016/j.mib.2010.12.003  0.72
2011 Hovhannisyan Z, Treatman J, Littman DR, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 140: 957-65. PMID 21147109 DOI: 10.1053/j.gastro.2010.12.002  0.72
2011 Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR. A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells (Nature (2010) 467, (214-217)) Nature. 470: 424. DOI: 10.1038/nature09813  0.72
2010 Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR. A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. Nature. 467: 214-7. PMID 20829794 DOI: 10.1038/nature09337  0.72
2010 Chong MM, Zhang G, Cheloufi S, Neubert TA, Hannon GJ, Littman DR. Canonical and alternate functions of the microRNA biogenesis machinery. Genes & Development. 24: 1951-60. PMID 20713509 DOI: 10.1101/gad.1953310  0.72
2010 Wu HJ, Ivanov II, Darce J, Hattori K, Shima T, Umesaki Y, Littman DR, Benoist C, Mathis D. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity. 32: 815-27. PMID 20620945 DOI: 10.1016/j.immuni.2010.06.001  0.72
2010 Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ, Powrie F. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature. 464: 1371-5. PMID 20393462 DOI: 10.1038/nature08949  0.72
2010 Chong MM, Simpson N, Ciofani M, Chen G, Collins A, Littman DR. Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. Genes & Development. 24: 659-69. PMID 20360383 DOI: 10.1101/gad.1901610  0.72
2010 Littman DR, Rudensky AY. Th17 and regulatory T cells in mediating and restraining inflammation. Cell. 140: 845-58. PMID 20303875 DOI: 10.1016/j.cell.2010.02.021  0.72
2010 Ivanov II, Littman DR. Segmented filamentous bacteria take the stage. Mucosal Immunology. 3: 209-12. PMID 20147894 DOI: 10.1038/mi.2010.3  0.72
2010 El Hed A, Khaitan A, Kozhaya L, Manel N, Daskalakis D, Borkowsky W, Valentine F, Littman DR, Unutmaz D. Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection. The Journal of Infectious Diseases. 201: 843-54. PMID 20144043 DOI: 10.1086/651021  0.72
2010 Trampont PC, Tosello-Trampont AC, Shen Y, Duley AK, Sutherland AE, Bender TP, Littman DR, Ravichandran KS. CXCR4 acts as a costimulator during thymic beta-selection. Nature Immunology. 11: 162-70. PMID 20010845 DOI: 10.1038/ni.1830  0.72
2010 Jacob B, Osato M, Yamashita N, Wang CQ, Taniuchi I, Littman DR, Asou N, Ito Y. Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. Blood. 115: 1610-20. PMID 20008790 DOI: 10.1182/blood-2009-07-232249  0.72
2010 Chong MMW, Zhang G, Cheloufi S, Neubert TA, Hannon GJ, Littman DR. Canonical and alternate functions of the microRNA biogenesis machinery (Genes & Development (2010) 24, (1951-1960)) Genes and Development. 24: 2228.  0.72
2009 Klunker S, Chong MM, Mantel PY, Palomares O, Bassin C, Ziegler M, Rückert B, Meiler F, Akdis M, Littman DR, Akdis CA. Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. The Journal of Experimental Medicine. 206: 2701-15. PMID 19917773 DOI: 10.1084/jem.20090596  0.72
2009 Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, Tanoue T, Imaoka A, Itoh K, Takeda K, Umesaki Y, ... ... Littman DR, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 139: 485-98. PMID 19836068 DOI: 10.1016/j.cell.2009.09.033  0.72
2009 Feuerer M, Shen Y, Littman DR, Benoist C, Mathis D. How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. Immunity. 31: 654-64. PMID 19818653 DOI: 10.1016/j.immuni.2009.08.023  0.72
2009 Rudra D, Egawa T, Chong MM, Treuting P, Littman DR, Rudensky AY. Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells. Nature Immunology. 10: 1170-7. PMID 19767756 DOI: 10.1038/ni.1795  0.72
2009 Kim JK, Klinger M, Benjamin J, Xiao Y, Erle DJ, Littman DR, Killeen N. Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking. Plos One. 4: e6580. PMID 19668367 DOI: 10.1371/journal.pone.0006580  0.72
2009 Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity. 30: 646-55. PMID 19464987 DOI: 10.1016/j.immuni.2009.05.001  0.72
2009 Zhou L, Littman DR. Transcriptional regulatory networks in Th17 cell differentiation. Current Opinion in Immunology. 21: 146-52. PMID 19328669 DOI: 10.1016/j.coi.2009.03.001  0.72
2009 Voo KS, Wang YH, Santori FR, Boggiano C, Wang YH, Arima K, Bover L, Hanabuchi S, Khalili J, Marinova E, Zheng B, Littman DR, Liu YJ. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proceedings of the National Academy of Sciences of the United States of America. 106: 4793-8. PMID 19273860 DOI: 10.1073/pnas.0900408106  0.72
2009 Browne EP, Littman DR. Myd88 is required for an antibody response to retroviral infection. Plos Pathogens. 5: e1000298. PMID 19214214 DOI: 10.1371/journal.ppat.1000298  0.72
2009 Collins A, Littman DR, Taniuchi I. RUNX proteins in transcription factor networks that regulate T-cell lineage choice. Nature Reviews. Immunology. 9: 106-15. PMID 19165227 DOI: 10.1038/nri2489  0.72
2009 Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT. Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Retrovirology. 6: 2. PMID 19144136 DOI: 10.1186/1742-4690-6-2  0.72
2009 Takatori H, Kanno Y, Watford WT, Tato CM, Weiss G, Ivanov II, Littman DR, O'Shea JJ. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. The Journal of Experimental Medicine. 206: 35-41. PMID 19114665 DOI: 10.1084/jem.20072713  0.72
2009 Luci C, Reynders A, Ivanov II, Cognet C, Chiche L, Chasson L, Hardwigsen J, Anguiano E, Banchereau J, Chaussabel D, Dalod M, Littman DR, Vivier E, Tomasello E. Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nature Immunology. 10: 75-82. PMID 19029904 DOI: 10.1038/ni.1681  0.72
2009 Leppkes M, Becker C, Ivanov II, Hirth S, Wirtz S, Neufert C, Pouly S, Murphy AJ, Valenzuela DM, Yancopoulos GD, Becher B, Littman DR, Neurath MF. RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology. 136: 257-67. PMID 18992745 DOI: 10.1053/j.gastro.2008.10.018  0.72
2008 Kao H, Lin J, Littman DR, Shaw AS, Allen PM. Regulated movement of CD4 in and out of the immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 181: 8248-57. PMID 19050241  0.72
2008 Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB, Finlay BB, Littman DR. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host & Microbe. 4: 337-49. PMID 18854238 DOI: 10.1016/j.chom.2008.09.009  0.72
2008 Medzhitov R, Littman D. HIV immunology needs a new direction. Nature. 455: 591. PMID 18833256 DOI: 10.1038/455591a  0.72
2008 Tassi I, Cella M, Presti R, Colucci A, Gilfillan S, Littman DR, Colonna M. NK cell-activating receptors require PKC-theta for sustained signaling, transcriptional activation, and IFN-gamma secretion. Blood. 112: 4109-16. PMID 18784374 DOI: 10.1182/blood-2008-02-139527  0.72
2008 Egawa T, Littman DR. ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nature Immunology. 9: 1131-9. PMID 18776905 DOI: 10.1038/ni.1652  0.72
2008 Chong MM, Rasmussen JP, Rudensky AY, Rundensky AY, Littman DR. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. The Journal of Experimental Medicine. 205: 2005-17. PMID 18725527 DOI: 10.1084/jem.20081219  0.72
2008 Quezada SA, Peggs KS, Simpson TR, Shen Y, Littman DR, Allison JP. Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. The Journal of Experimental Medicine. 205: 2125-38. PMID 18725522 DOI: 10.1084/jem.20080099  0.72
2008 Tsuji M, Suzuki K, Kitamura H, Maruya M, Kinoshita K, Ivanov II, Itoh K, Littman DR, Fagarasan S. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity. 29: 261-71. PMID 18656387 DOI: 10.1016/j.immuni.2008.05.014  0.72
2008 Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nature Immunology. 9: 641-9. PMID 18454151 DOI: 10.1038/ni.1610  0.72
2008 Zhang JX, Diehl GE, Littman DR. Relief of preintegration inhibition and characterization of additional blocks for HIV replication in primary mouse T cells. Plos One. 3: e2035. PMID 18446227 DOI: 10.1371/journal.pone.0002035  0.72
2008 Scandella E, Bolinger B, Lattmann E, Miller S, Favre S, Littman DR, Finke D, Luther SA, Junt T, Ludewig B. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nature Immunology. 9: 667-75. PMID 18425132 DOI: 10.1038/ni.1605  0.72
2008 Valdez Y, Diehl GE, Vallance BA, Grassl GA, Guttman JA, Brown NF, Rosenberger CM, Littman DR, Gros P, Finlay BB. Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular Microbiology. 10: 1646-61. PMID 18397382 DOI: 10.1111/j.1462-5822.2008.01155.x  0.72
2008 Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, Shen Y, Du J, Rubtsov YP, Rudensky AY, Ziegler SF, Littman DR. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 453: 236-40. PMID 18368049 DOI: 10.1038/nature06878  0.72
2008 Egawa T, Kreslavsky T, Littman DR, von Boehmer H. Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping. Plos One. 3: e1512. PMID 18231598 DOI: 10.1371/journal.pone.0001512  0.72
2008 Gross O, Grupp C, Steinberg C, Zimmermann S, Strasser D, Hannesschläger N, Reindl W, Jonsson H, Huo H, Littman DR, Peschel C, Yokoyama WM, Krug A, Ruland J. Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production. Blood. 112: 2421-8. PMID 18192506 DOI: 10.1182/blood-2007-11-123513  0.72
2008 Browne EP, Littman DR. Species-specific restriction of apobec3-mediated hypermutation. Journal of Virology. 82: 1305-13. PMID 18032489 DOI: 10.1128/JVI.01371-07  0.72
2008 Chong MMW, Rasmussen JP, Rudensky AY, Littman DR. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (Journal of Experimental Medicine (2008) 205, 9 (2005-2017)) Journal of Experimental Medicine. 205: 2449. DOI: 10.1084/jem.20071219090508c  0.72
2008 Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells (Journal of Experimental Medicine (2007) 204, 8, (1945-1957)) Journal of Experimental Medicine. 205: 1939. DOI: 10.1084/jem.20070133071408c  0.72
2007 Ivanov II, Zhou L, Littman DR. Transcriptional regulation of Th17 cell differentiation. Seminars in Immunology. 19: 409-17. PMID 18053739 DOI: 10.1016/j.smim.2007.10.011  0.72
2007 Motoda L, Osato M, Yamashita N, Jacob B, Chen LQ, Yanagida M, Ida H, Wee HJ, Sun AX, Taniuchi I, Littman D, Ito Y. Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult. Stem Cells (Dayton, Ohio). 25: 2976-86. PMID 17823240 DOI: 10.1634/stemcells.2007-0061  0.72
2007 Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. The Journal of Experimental Medicine. 204: 1945-57. PMID 17646406 DOI: 10.1084/jem.20070133  0.72
2007 Naoe Y, Setoguchi R, Akiyama K, Muroi S, Kuroda M, Hatam F, Littman DR, Taniuchi I. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. The Journal of Experimental Medicine. 204: 1749-55. PMID 17646405 DOI: 10.1084/jem.20062456  0.72
2007 Zhou L, Ivanov II, Spolski R, Min R, Shenderov K, Egawa T, Levy DE, Leonard WJ, Littman DR. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nature Immunology. 8: 967-74. PMID 17581537 DOI: 10.1038/ni1488  0.72
2007 Sims TN, Soos TJ, Xenias HS, Dubin-Thaler B, Hofman JM, Waite JC, Cameron TO, Thomas VK, Varma R, Wiggins CH, Sheetz MP, Littman DR, Dustin ML. Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell. 129: 773-85. PMID 17512410 DOI: 10.1016/j.cell.2007.03.037  0.72
2007 Misra RS, Russell JQ, Koenig A, Hinshaw-Makepeace JA, Wen R, Wang D, Huo H, Littman DR, Ferch U, Ruland J, Thome M, Budd RC. Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation. The Journal of Biological Chemistry. 282: 19365-74. PMID 17462996 DOI: 10.1074/jbc.M610610200  0.72
2007 Littman DR, Singh H. Immunology. Asymmetry and immune memory. Science (New York, N.Y.). 315: 1673-4. PMID 17379796 DOI: 10.1126/science.1141184  0.72
2007 Boggiano C, Littman DR. HIV's vagina travelogue. Immunity. 26: 145-7. PMID 17307703 DOI: 10.1016/j.immuni.2007.02.001  0.72
2007 Boggiano C, Manel N, Littman DR. Dendritic cell-mediated trans-enhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN. Journal of Virology. 81: 2519-23. PMID 17182696 DOI: 10.1128/JVI.01661-06  0.72
2006 Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 126: 1121-33. PMID 16990136 DOI: 10.1016/j.cell.2006.07.035  0.72
2006 Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, Wei K, McMaster BE, Wright K, Howard MC, Schall TJ. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. The Journal of Experimental Medicine. 203: 2201-13. PMID 16940167 DOI: 10.1084/jem.20052144  0.72
2006 Ivanov II, Diehl GE, Littman DR. Lymphoid tissue inducer cells in intestinal immunity. Current Topics in Microbiology and Immunology. 308: 59-82. PMID 16922086  0.72
2006 Soos TJ, Sims TN, Barisoni L, Lin K, Littman DR, Dustin ML, Nelson PJ. CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney International. 70: 591-6. PMID 16760907 DOI: 10.1038/sj.ki.5001567  0.72
2006 Cardona AE, Pioro EP, Sasse ME, Kostenko V, Cardona SM, Dijkstra IM, Huang D, Kidd G, Dombrowski S, Dutta R, Lee JC, Cook DN, Jung S, Lira SA, Littman DR, et al. Control of microglial neurotoxicity by the fractalkine receptor. Nature Neuroscience. 9: 917-24. PMID 16732273 DOI: 10.1038/nn1715  0.72
2006 Huang D, Shi FD, Jung S, Pien GC, Wang J, Salazar-Mather TP, He TT, Weaver JT, Ljunggren HG, Biron CA, Littman DR, Ransohoff RM. The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 896-905. PMID 16675847 DOI: 10.1096/fj.05-5465com  0.72
2006 Sun J, Soos T, Kewalramani VN, Osiecki K, Zheng JH, Falkin L, Santambrogio L, Littman DR, Goldstein H. CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate. Journal of Virology. 80: 1850-62. PMID 16439541 DOI: 10.1128/JVI.80.4.1850-1862.2006  0.72
2006 Fogg DK, Sibon C, Miled C, Jung S, Aucouturier P, Littman DR, Cumano A, Geissmann F. A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science (New York, N.Y.). 311: 83-7. PMID 16322423 DOI: 10.1126/science.1117729  0.72
2005 Browne EP, Li J, Chong M, Littman DR. Virus-host interactions: new insights from the small RNA world. Genome Biology. 6: 238. PMID 16277756 DOI: 10.1186/gb-2005-6-11-238  0.72
2005 Zaft T, Sapoznikov A, Krauthgamer R, Littman DR, Jung S. CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 6428-35. PMID 16272295  0.72
2005 Vilz TO, Moepps B, Engele J, Molly S, Littman DR, Schilling K. The SDF-1/CXCR4 pathway and the development of the cerebellar system. The European Journal of Neuroscience. 22: 1831-9. PMID 16262623 DOI: 10.1111/j.1460-9568.2005.04378.x  0.72
2005 Odemis V, Lamp E, Pezeshki G, Moepps B, Schilling K, Gierschik P, Littman DR, Engele J. Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis. Molecular and Cellular Neurosciences. 30: 494-505. PMID 16198599 DOI: 10.1016/j.mcn.2005.07.019  0.72
2005 Collins A, Littman DR. Selection and lineage specification in the thymus: Commitment 4-stalled Immunity. 23: 4-5. PMID 16039574 DOI: 10.1016/j.immuni.2005.07.003  0.72
2005 Grueter B, Petter M, Egawa T, Laule-Kilian K, Aldrian CJ, Wuerch A, Ludwig Y, Fukuyama H, Wardemann H, Waldschuetz R, Möröy T, Taniuchi I, Steimle V, Littman DR, Ehlers M. Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 1694-705. PMID 16034110  0.72
2005 Wang X, Blagden C, Fan J, Nowak SJ, Taniuchi I, Littman DR, Burden SJ. Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle. Genes & Development. 19: 1715-22. PMID 16024660 DOI: 10.1101/gad.1318305  0.72
2005 Egawa T, Eberl G, Taniuchi I, Benlagha K, Geissmann F, Hennighausen L, Bendelac A, Littman DR. Genetic evidence supporting selection of the Vα14i NKT cell lineage from double-positive thymocyte precursors Immunity. 22: 705-716. PMID 15963785 DOI: 10.1016/j.immuni.2005.03.011  0.72
2005 Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB. ATP mediates rapid microglial response to local brain injury in vivo. Nature Neuroscience. 8: 752-8. PMID 15895084 DOI: 10.1038/nn1472  0.72
2005 Geissmann F, Cameron TO, Sidobre S, Manlongat N, Kronenberg M, Briskin MJ, Dustin ML, Littman DR. Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids Plos Biology.. 3: e113. PMID 15799695 DOI: 10.1371/journal.pbio.0030113  0.72
2005 Feik N, Bilic I, Tinhofer J, Unger B, Littman DR, Ellmeier W. Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development Journal of Immunology. 174: 1513-1524. PMID 15661911  0.72
2005 Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, Vyas JM, Boes M, Ploegh HL, Fox JG, Littman DR, Reinecker HC. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance Science. 307: 254-258. PMID 15653504 DOI: 10.1126/science.1102901  0.72
2004 Nie Y, Waite J, Brewer F, Sunshine MJ, Littman DR, Zou YR. The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity Journal of Experimental Medicine. 200: 1145-1156. PMID 15520246 DOI: 10.1084/jem.20041185  0.72
2004 Baumann JG, Unutmaz D, Miller MD, Breun SK, Grill SM, Mirro J, Littman DR, Rein A, KewalRamani VN. Murine T cells potently restrict human immunodeficiency virus infection. Journal of Virology. 78: 12537-47. PMID 15507641 DOI: 10.1128/JVI.78.22.12537-12547.2004  0.72
2004 Kim JK, Fillmore JJ, Sunshine MJ, Albrecht B, Higashimori T, Kim DW, Liu ZX, Soos TJ, Cline GW, O'Brien WR, Littman DR, Shulman GI. PKC-theta knockout mice are protected from fat-induced insulin resistance. The Journal of Clinical Investigation. 114: 823-7. PMID 15372106 DOI: 10.1172/JCI22230  0.72
2004 Li Y, Soos TJ, Li X, Wu J, Degennaro M, Sun X, Littman DR, Birnbaum MJ, Polakiewicz RD. Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). The Journal of Biological Chemistry. 279: 45304-7. PMID 15364919 DOI: 10.1074/jbc.C400186200  0.72
2004 Kawakami Y, Nishimoto H, Kitaura J, Maeda-Yamamoto M, Kato RM, Littman DR, Leitges M, Rawlings DJ, Kawakami T. Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion. The Journal of Biological Chemistry. 279: 47720-5. PMID 15364915 DOI: 10.1074/jbc.M408797200  0.72
2004 Marsland BJ, Soos TJ, Späth G, Littman DR, Kopf M. Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. The Journal of Experimental Medicine. 200: 181-9. PMID 15263025 DOI: 10.1084/jem.20032229  0.72
2004 Taniuchi I, Littman DR. Epigenetic gene silencing by Runx proteins Oncogene. 23: 4341-4345. PMID 15156191 DOI: 10.1038/sj.onc.1207671  0.72
2004 Taniuchi I, Ellmeier W, Littman DR. The CD4/CD8 lineage choice: New insights into epigenetic regulation during T cell development Advances in Immunology. 83: 55-89. PMID 15135628 DOI: 10.1016/S0065-2776(04)83002-5  0.72
2004 Fonteneau JF, Larsson M, Beignon AS, McKenna K, Dasilva I, Amara A, Liu YJ, Lifson JD, Littman DR, Bhardwaj N. Human Immunodeficiency Virus Type 1 Activates Plasmacytoid Dendritic Cells and Concomitantly Induces the Bystander Maturation of Myeloid Dendritic Cells Journal of Virology. 78: 5223-5232. PMID 15113904 DOI: 10.1128/JVI.78.10.5223-5232.2004  0.72
2004 Madakamutil LT, Christen U, Lena CJ, Wang-Zhu Y, Attinger A, Sundarrajan M, Ellmeier W, von Herrath MG, Jensen P, Littman DR, Cheroutre H. CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors. Science (New York, N.Y.). 304: 590-3. PMID 15105501 DOI: 10.1126/science.1092316  0.72
2004 Berg-Brown NN, Gronski MA, Jones RG, Elford AR, Deenick EK, Odermatt B, Littman DR, Ohashi PS. PKCθ Signals Activation versus Tolerance In Vivo Journal of Experimental Medicine. 199: 743-752. PMID 15024044 DOI: 10.1084/jem.20031022  0.72
2003 Eberl G, Littman DR. The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches Immunological Reviews. 195: 81-90. PMID 12969312 DOI: 10.1034/j.1600-065X.2003.00074.x  0.72
2003 Amara A, Littman DR. After Hrs with HIV Journal of Cell Biology. 162: 371-375. PMID 12900390 DOI: 10.1083/jcb.200307062  0.72
2003 Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties Immunity. 19: 71-82. PMID 12871640 DOI: 10.1016/S1074-7613(03)00174-2  0.72
2003 Egawa T, Albrecht B, Favier B, Sunshine MJ, Mirchandani K, O'Brien W, Thome M, Littman DR. Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Current Biology : Cb. 13: 1252-8. PMID 12867038 DOI: 10.1016/S0960-9822(03)00491-3  0.72
2003 Chalasani SH, Baribaud F, Coughlan CM, Sunshine MJ, Lee VM, Doms RW, Littman DR, Raper JA. The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4601-12. PMID 12805300  0.72
2003 Chalasani SH, Sabelko KA, Sunshine MJ, Littman DR, Raper JA. A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1360-71. PMID 12598624  0.72
2003 Huo Y, Schober A, Forlow SB, Smith DF, Hyman MC, Jung S, Littman DR, Weber C, Ley K. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E Nature Medicine. 9: 61-67. PMID 12483207 DOI: 10.1038/nm810  0.72
2002 Taniuchi I, Osato M, Egawa T, Sunshine MJ, Bae SC, Komori T, Ito Y, Littman DR. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development Cell. 111: 621-633. PMID 12464175 DOI: 10.1016/S0092-8674(02)01111-X  0.72
2002 Taniuchi I, Sunshine MJ, Festenstein R, Littman DR. Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation Molecular Cell. 10: 1083-1096. PMID 12453416 DOI: 10.1016/S1097-2765(02)00735-9  0.72
2002 Ohlrogge W, Haag F, Löhler J, Seman M, Littman DR, Killeen N, Koch-Nolte F. Generation and characterization of ecto-ADP-ribosyltransferase ART2.1/ART2.2-deficient mice. Molecular and Cellular Biology. 22: 7535-42. PMID 12370300 DOI: 10.1128/MCB.22.21.7535-7542.2002  0.72
2002 Jung S, Unutmaz D, Wong P, Sano G, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Zavala F, Pamer EG, Littman DR, Lang RA. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17: 211-20. PMID 12196292 DOI: 10.1016/S1074-7613(02)00365-5  0.72
2002 Bagri A, Gurney T, He X, Zou YR, Littman DR, Tessier-Lavigne M, Pleasure SJ. The chemokine SDF1 regulates migration of dentate granule cells. Development (Cambridge, England). 129: 4249-60. PMID 12183377  0.72
2002 Okada T, Ngo VN, Ekland EH, Förster R, Lipp M, Littman DR, Cyster JG. Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. The Journal of Experimental Medicine. 196: 65-75. PMID 12093871 DOI: 10.1084/jem.20020201  0.72
2002 Ellmeier W, Sunshine MJ, Maschek R, Littman DR. Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression Immunity. 16: 623-634. PMID 12049715 DOI: 10.1016/S1074-7613(02)00309-6  0.72
2002 Winoto A, Littman DR. Nuclear hormone receptors in T lymphocytes. Cell. 109: S57-66. PMID 11983153 DOI: 10.1016/S0092-8674(02)00710-9  0.72
2002 Arendt CW, Albrecht B, Soos TJ, Littman DR. Protein kinase C-theta;: signaling from the center of the T-cell synapse. Current Opinion in Immunology. 14: 323-30. PMID 11973130 DOI: 10.1016/S0952-7915(02)00346-1  0.72
2002 Guo J, Hawwari A, Li H, Sun Z, Mahanta SK, Littman DR, Krangel MS, He YW. Regulation of the TCRα repertoire by the survival window of CD4+CD8+ thymocytes Nature Immunology. 3: 469-476. PMID 11967541 DOI: 10.1038/ni791  0.72
2002 Keppler OT, Welte FJ, Ngo TA, Chin PS, Patton KS, Tsou CL, Abbey NW, Sharkey ME, Grant RM, You Y, Scarborough JD, Ellmeier W, Littman DR, Stevenson M, Charo IF, et al. Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1 Journal of Experimental Medicine. 195: 719-736. PMID 11901198 DOI: 10.1084/jem.20011549  0.72
2002 Kwon DS, Gregorio G, Bitton N, Hendrickson WA, Littman DR. DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection Immunity. 16: 135-144. PMID 11825572 DOI: 10.1016/S1074-7613(02)00259-5  0.72
2002 Harmsen A, Kusser K, Hartson L, Tighe M, Sunshine MJ, Sedgwick JD, Choi Y, Littman DR, Randall TD. Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependent. Journal of Immunology (Baltimore, Md. : 1950). 168: 986-90. PMID 11801629  0.72
2001 Arendt CW, Littman DR. HIV: master of the host cell. Genome Biology. 2: REVIEWS1030. PMID 11737949  0.72
2001 Palframan RT, Jung S, Cheng G, Weninger W, Luo Y, Dorf M, Littman DR, Rollins BJ, Zweerink H, Rot A, Von Andrian UH. Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues Journal of Experimental Medicine. 194: 1361-1373. PMID 11696600 DOI: 10.1084/jem.194.9.1361  0.72
2001 Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K. The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium Journal of Clinical Investigation. 108: 1307-1314. PMID 11696575 DOI: 10.1172/JCI200112877  0.72
2001 Zou YR, Sunshine MJ, Taniuchi I, Hatam F, Killeen N, Littman DR. Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage Nature Genetics. 29: 332-336. PMID 11687799 DOI: 10.1038/ng750  0.72
2001 Baribaud F, Pöhlmann S, Sparwasser T, Kimata MT, Choi YK, Haggarty BS, Ahmad N, Macfarlan T, Edwards TG, Leslie GJ, Arnason J, Reinhart TA, Kimata JT, Littman DR, Hoxie JA, et al. Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN. Journal of Virology. 75: 10281-9. PMID 11581396 DOI: 10.1128/JVI.75.21.10281-10289.2001  0.72
2001 Hargreaves DC, Hyman PL, Lu TT, Ngo VN, Bidgol A, Suzuki G, Zou YR, Littman DR, Cyster JG. A coordinated change in chemokine responsiveness guides plasma cell movements. The Journal of Experimental Medicine. 194: 45-56. PMID 11435471 DOI: 10.1084/jem.194.1.45  0.72
2001 Pierani A, Moran-Rivard L, Sunshine MJ, Littman DR, Goulding M, Jessell TM. Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 29: 367-84. PMID 11239429 DOI: 10.1016/S0896-6273(01)00212-4  0.72
2001 Wolfer A, Bakker T, Wilson A, Nicolas M, Ioannidis V, Littman DR, Wilson CB, Held W, MacDonald HR, Radtke F. Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development Nature Immunology. 2: 235-241. PMID 11224523 DOI: 10.1038/85294  0.72
2001 Browning CM, Smith MJ, Clark NM, Lane BR, Parada C, Montano M, KewalRamani VN, Littman DR, Essex M, Roeder RG, Markovitz DM. Human GLI-2 is a tat activation response element-independent Tat cofactor. Journal of Virology. 75: 2314-23. PMID 11160734 DOI: 10.1128/JVI.75.5.2314-2323.2001  0.72
2000 Ellmeier W, Jung S, Sunshine MJ, Hatam F, Xu Y, Baltimore D, Mano H, Littman DR. Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. The Journal of Experimental Medicine. 192: 1611-24. PMID 11104803 DOI: 10.1084/jem.192.11.1611  0.72
2000 Unutmaz D, Xiang W, Sunshine MJ, Campbell J, Butcher E, Littman DR. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse Journal of Immunology. 165: 3284-3292. PMID 10975845  0.72
2000 Sun Z, Unutmaz D, Zou YR, Sunshine MJ, Pierani A, Brenner-Morton S, Mebius RE, Littman DR. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science (New York, N.Y.). 288: 2369-73. PMID 10875923 DOI: 10.1126/science.288.5475.2369  0.72
2000 Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, Littman DR. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Molecular and Cellular Biology. 20: 4106-14. PMID 10805752 DOI: 10.1128/MCB.20.11.4106-4114.2000  0.72
2000 Sun Z, Arendt CW, Ellmeier W, Schaeffer EM, Sunshine MJ, Gandhi L, Annes J, Petrzilka D, Kupfer A, Schwartzberg PL, Littman DR. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature. 404: 402-7. PMID 10746729 DOI: 10.1038/35006090  0.72
2000 Geijtenbeek TBH, Kwon DS, Torensma R, Van Vliet SJ, Van Duijnhoven GCF, Middel J, Cornelissen ILMHA, Nottet HSLM, KewalRamani VN, Littman DR, Figdor CG, Van Kooyk Y. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells Cell. 100: 587-597. PMID 10721995  0.72
1999 Littman DR, Sun Z, Unutmaz D, Sunshine MJ, Petrie HT, Zou YR. Role of the nuclear hormone receptor RORγ in transcriptional regulation, thymocyte survival, and lymphoid organogenesis Cold Spring Harbor Symposia On Quantitative Biology. 64: 373-381. PMID 11232310  0.72
1999 Fowell DJ, Shinkai K, Liao XC, Beebe AM, Coffman RL, Littman DR, Locksley RM. Impaired NFATc translocation and failure of Th2 development in Itk- deficient CD4+ T cells Immunity. 11: 399-409. PMID 10549622 DOI: 10.1016/S1074-7613(00)80115-6  0.72
1999 Vidal K, Daniel C, Hill M, Littman DR, Allen PM. Differential requirements for CD4 in TCR-ligand interactions Journal of Immunology. 163: 4811-4818. PMID 10528181  0.72
1999 Unutmaz D, KewalRamani VN, Marmon S, Littman DR. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes Journal of Experimental Medicine. 189: 1735-1746. PMID 10359577 DOI: 10.1084/jem.189.11.1735  0.72
1999 Ellmeier W, Sawada S, Littman DR. The regulation of CD4 and CD8 coreceptor gene expression during T cell development Annual Review of Immunology. 17: 523-554. PMID 10358767 DOI: 10.1146/annurev.immunol.17.1.523  0.72
1999 Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (New York, N.Y.). 284: 638-41. PMID 10213685 DOI: 10.1126/science.284.5414.638  0.72
1999 Shelbourne PF, Killeen N, Hevner RF, Johnston HM, Tecott L, Lewandoski M, Ennis M, Ramirez L, Li Z, Iannicola C, Littman DR, Myers RM. A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice. Human Molecular Genetics. 8: 763-74. PMID 10196365  0.72
1999 Mörner A, Björndal A, Albert J, Kewalramani VN, Littman DR, Inoue R, Thorstensson R, Fenyö EM, Björling E. Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV- 1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage Journal of Virology. 73: 2343-2349. PMID 9971817  0.72
1999 LaCasse RA, Follis KE, Trahey M, Scarborough JD, Littman DR, Nunberg JH. Fusion-competent vaccines: Broad neutralization of primary isolates of HIV Science. 283: 357-362. PMID 9888845 DOI: 10.1126/science.283.5400.357  0.72
1999 Kimata JT, Gosink JJ, Kewalramani VN, Rudensey LM, Littman DR, Overbaugh J. Coreceptor specificity of temporal variants of simian immunodeficiency virus Mne Journal of Virology. 73: 1655-1660. PMID 9882375  0.72
1998 Garber ME, Wei P, KewalRamani VN, Mayall TP, Herrmann CH, Rice AP, Littman DR, Jones KA. The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes & Development. 12: 3512-27. PMID 9832504  0.72
1998 Ellmeier W, Sunshine MJ, Losos K, Littman DR. Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells Immunity. 9: 485-496. PMID 9806635 DOI: 10.1016/S1074-7613(00)80632-9  0.72
1998 Zhang YJ, Dragic T, Cao Y, Kostrikis L, Kwon DS, Littman DR, Kewalramani VN, Moore JP. Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro Journal of Virology. 72: 9337-9344. PMID 9765485  0.72
1998 Hill CM, Kwon D, Jones M, Davis CB, Marmon S, Daugherty BL, DeMartino JA, Springer MS, Unutmaz D, Littman DR. The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins. Virology. 248: 357-71. PMID 9721244 DOI: 10.1006/viro.1998.9283  0.72
1998 Cecilia D, Kewalramanl VN, O'Leary J, Volsky B, Nyambi P, Burda S, Xu S, Littman DR, Zolla-Pazner S. Neutralization profiles of primary human immunodeficiency virus type 1 isolates in the context of coreceptor usage Journal of Virology. 72: 6988-6996. PMID 9696790  0.72
1998 Langlois AJ, Desrosiers RC, Lewis MG, Kewalramani VN, Littman DR, Zhou JY, Manson K, Wyand MS, Bolognesi DP, Montefiori DC. Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus Journal of Virology. 72: 6950-6955. PMID 9658152  0.72
1998 Unutmaz D, KewalRamani VN, Littman DR. G protein-coupled receptors in HIV and SIV entry: New perspectives on lentivirus-host interactions and on the utility of animal models Seminars in Immunology. 10: 225-236. PMID 9653049 DOI: 10.1006/smim.1998.0134  0.72
1998 Irie HY, Mong MS, Itano A, Casey Crooks ME, Littman DR, Burakoff SJ, Robey E. The cytoplasmic domain of CD8β regulates Lck kinase activation and CD8 T cell development Journal of Immunology. 161: 183-191. PMID 9647223  0.72
1998 Zou YR, Kottman AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in heaematopolesis and in cerebellar development Nature. 393: 595-599. PMID 9634238 DOI: 10.1038/31269  0.72
1998 Littman DR. Chemokine receptors: Keys to AIDS pathogenesis? Cell. 93: 677-680. PMID 9630212 DOI: 10.1016/S0092-8674(00)81429-4  0.72
1998 Michael NL, Nelson JA, KewalRamani VN, Chang G, O'Brien SJ, Mascola JR, Volsky B, Louder M, White GC, Littman DR, Swanstrom R, O'Brien TR. Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32. Journal of Virology. 72: 6040-7. PMID 9621067  0.72
1998 Tscherning C, Alaeus A, Fredriksson R, Björndal A, Deng H, Littman DR, Fenyö EM, Albert J. Differences in chemokine coreceptor usage between genetic subtypes of HIV-1 Virology. 241: 181-188. PMID 9499793 DOI: 10.1006/viro.1997.8980  0.72
1998 Trkola A, Ketas T, Kewalramani VN, Endorf F, Binley JM, Katinger H, Robinson J, Littman DR, Moore JP. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage Journal of Virology. 72: 1876-1885. PMID 9499039  0.72
1988 Littman DR, Maddon PJ, Axel R. Corrected CD4 sequence. Cell. 55: 541. PMID 3263213  0.72
1986 McDougal JS, Maddon PJ, Dalgleish AG, Clapham PR, Littman DR, Godfrey M, Maddon DE, Chess L, Weiss RA, Axel R. The T4 glycoprotein is a cell-surface receptor for the AIDS virus. Cold Spring Harbor Symposia On Quantitative Biology. 51: 703-11. PMID 3495395  0.72
1986 Isobe M, Huebner K, Maddon PJ, Littman DR, Axel R, Croce CM. The gene encoding the T-cell surface protein T4 is located on human chromosome 12. Proceedings of the National Academy of Sciences of the United States of America. 83: 4399-402. PMID 3086883  0.72
1985 Littman DR, Thomas Y, Maddon PJ, Chess L, Axel R. The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytes. Cell. 40: 237-46. PMID 3871356 DOI: 10.1016/0092-8674(85)90138-2  0.72
1985 Maddon PJ, Littman DR, Godfrey M, Maddon DE, Chess L, Axel R. The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell. 42: 93-104. PMID 2990730 DOI: 10.1016/S0092-8674(85)80105-7  0.72
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