Year |
Citation |
Score |
2024 |
Mercer JAM, DeCarlo SJ, Roy Burman SS, Sreekanth V, Nelson AT, Hunkeler M, Chen PJ, Donovan KA, Kokkonda P, Tiwari PK, Shoba VM, Deb A, Choudhary A, Fischer ES, Liu DR. Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science (New York, N.Y.). 383: eadk4422. PMID 38484051 DOI: 10.1126/science.adk4422 |
0.789 |
|
2023 |
Nguyen TM, Sreekanth V, Deb A, Kokkonda P, Tiwari PK, Donovan KA, Shoba V, Chaudhary SK, Mercer JAM, Lai S, Sadagopan A, Jan M, Fischer ES, Liu DR, Ebert BL, ... Choudhary A, et al. Proteolysis-targeting chimeras with reduced off-targets. Nature Chemistry. PMID 38110475 DOI: 10.1038/s41557-023-01379-8 |
0.782 |
|
2023 |
Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation. Journal of the American Chemical Society. PMID 37992275 DOI: 10.1021/jacs.3c06179 |
0.801 |
|
2023 |
Kahraman S, Shibue K, De Jesus DF, Kim H, Hu J, Manna D, Wagner BK, Choudhary A, Kulkarni RN. Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses. Elife. 12. PMID 37732504 DOI: 10.7554/eLife.85056 |
0.59 |
|
2023 |
Pergu R, Shoba VM, Chaudhary SK, Munkanatta Godage DNP, Deb A, Singha S, Dhawa U, Singh P, Anokhina V, Singh S, Siriwardena SU, Choudhary A. Development and Applications of Chimera Platforms for Tyrosine Phosphorylation. Acs Central Science. 9: 1558-1566. PMID 37637727 DOI: 10.1021/acscentsci.3c00200 |
0.777 |
|
2023 |
Singh S, Tian W, Severance ZC, Chaudhary SK, Anokhina V, Mondal B, Pergu R, Singh P, Dhawa U, Singha S, Choudhary A. Proximity-inducing modalities: the past, present, and future. Chemical Society Reviews. PMID 37477631 DOI: 10.1039/d2cs00943a |
0.76 |
|
2023 |
Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. Biorxiv : the Preprint Server For Biology. PMID 37461636 DOI: 10.1101/2023.07.07.548101 |
0.801 |
|
2023 |
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, ... ... Choudhary A, et al. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell Metabolism. PMID 37075753 DOI: 10.1016/j.cmet.2023.03.018 |
0.779 |
|
2023 |
Arp CJ, Reynders M, Sreekanth V, Kokkonda P, Pagano M, Choudhary A, Trauner D. Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation. Biorxiv : the Preprint Server For Biology. PMID 37066279 DOI: 10.1101/2023.04.09.536172 |
0.784 |
|
2023 |
Sreekanth V, Jan M, Zhao KT, Lim D, Davis JR, McConkey M, Kovalcik V, Barkal S, Law BK, Fife J, Tian R, Vinyard ME, Becerra B, Kampmann ME, Sherwood RI, ... ... Choudhary A, et al. A molecular glue approach to control the half-life of CRISPR-based technologies. Biorxiv : the Preprint Server For Biology. PMID 36945568 DOI: 10.1101/2023.03.12.531757 |
0.791 |
|
2023 |
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, ... ... Choudhary A, et al. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Biorxiv : the Preprint Server For Biology. PMID 36865221 DOI: 10.1101/2023.02.19.529127 |
0.783 |
|
2022 |
Lim D, Zhou Q, Cox KJ, Law BK, Lee M, Kokkonda P, Sreekanth V, Pergu R, Chaudhary SK, Gangopadhyay SA, Maji B, Lai S, Amako Y, Thompson DB, Subramanian HKK, ... ... Choudhary A, et al. A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules. Nature Cell Biology. PMID 36396978 DOI: 10.1038/s41556-022-01005-8 |
0.758 |
|
2022 |
Shoba VM, Munkanatta Godage DNP, Chaudhary SK, Deb A, Siriwardena SU, Choudhary A. Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins. Angewandte Chemie (International Ed. in English). e202202770. PMID 35641438 DOI: 10.1002/anie.202202770 |
0.794 |
|
2022 |
Yamada K, Deb A, Shoba VM, Lim D, Maji B, Modell AE, Choudhary A. Rational Design of Silicon-Based Zinc Ionophores. Angewandte Chemie (International Ed. in English). e202201698. PMID 35385189 DOI: 10.1002/anie.202201698 |
0.758 |
|
2021 |
Modell AE, Lim D, Nguyen TM, Sreekanth V, Choudhary A. CRISPR-based therapeutics: current challenges and future applications. Trends in Pharmacological Sciences. PMID 34952739 DOI: 10.1016/j.tips.2021.10.012 |
0.793 |
|
2021 |
Modell AE, Lai S, Nguyen TM, Choudhary A. Bifunctional modalities for repurposing protein function. Cell Chemical Biology. 28: 1081-1089. PMID 34270935 DOI: 10.1016/j.chembiol.2021.06.005 |
0.809 |
|
2021 |
Clemons PA, Bittker JA, Wagner FF, Hands A, Dančík V, Schreiber SL, Choudhary A, Wagner BK. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. Slas Discovery : Advancing Life Sciences R & D. 24725552211019410. PMID 34130532 DOI: 10.1177/24725552211019410 |
0.433 |
|
2021 |
Kahraman S, Manna D, Dirice E, Maji B, Small J, Wagner BK, Choudhary A, Kulkarni RN. Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells. Life Science Alliance. 4. PMID 33514654 DOI: 10.26508/lsa.202000840 |
0.778 |
|
2020 |
Cox KJ, Subramanian HKK, Samaniego CC, Franco E, Choudhary A. Correction: A universal method for sensitive and cell-free detection of CRISPR-associated nucleases. Chemical Science. 11: 10287. PMID 34094293 DOI: 10.1039/d0sc90196b |
0.752 |
|
2020 |
Sreekanth V, Zhou Q, Kokkonda P, Bermudez-Cabrera HC, Lim D, Law BK, Holmes BR, Chaudhary SK, Pergu R, Leger BS, Walker JA, Gifford DK, Sherwood RI, Choudhary A. Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes. Acs Central Science. 6: 2228-2237. PMID 33376784 DOI: 10.1021/acscentsci.0c00129 |
0.757 |
|
2020 |
Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. clustered regularly interspaced short palindromic repeat-Chemical and optical control of CRISPR-associated nucleases. Current Opinion in Chemical Biology. 60: 113-121. PMID 33253976 DOI: 10.1016/j.cbpa.2020.10.003 |
0.779 |
|
2020 |
Yang K, Lee M, Jones PA, Liu SS, Zhou A, Xu J, Sreekanth V, Wu JLY, Vo L, Lee EA, Pop R, Lee Y, Wagner BK, Melton DA, Choudhary A, et al. A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells. Science Advances. 6. PMID 33208361 DOI: 10.1126/sciadv.abc3207 |
0.775 |
|
2020 |
Lim D, Sreekanth V, Cox KJ, Law BK, Wagner BK, Karp JM, Choudhary A. Engineering designer beta cells with a CRISPR-Cas9 conjugation platform. Nature Communications. 11: 4043. PMID 32792475 DOI: 10.1038/S41467-020-17725-0 |
0.789 |
|
2020 |
Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Phosphorylation-Inducing Chimeric Small Molecules. Journal of the American Chemical Society. PMID 32787262 DOI: 10.1021/Jacs.0C05537 |
0.791 |
|
2020 |
López Del Amo V, Leger BS, Cox KJ, Gill S, Bishop AL, Scanlon GD, Walker JA, Gantz VM, Choudhary A. Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives. Cell Reports. 31: 107841. PMID 32610142 DOI: 10.1016/J.Celrep.2020.107841 |
0.787 |
|
2020 |
Modell AE, Siriwardena SU, Choudhary A. A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems. Biochemistry. 59: 1869-1870. PMID 32403926 DOI: 10.1021/Acs.Biochem.0C00273 |
0.749 |
|
2020 |
Lee M, Maji B, Manna D, Kahraman S, Elgamal RM, Small J, Kokkonda P, Vetere A, Goldberg JM, Lippard SJ, Kulkarni RN, Wagner BK, Choudhary A. Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells. Journal of the American Chemical Society. PMID 32175731 DOI: 10.1021/Jacs.0C00099 |
0.771 |
|
2020 |
Cox KJ, Subramanian HKK, Samaniego CC, Franco E, Choudhary A. Correction: A universal method for sensitive and cell-free detection of CRISPR-associated nucleases Chemical Science. DOI: 10.1039/D0Sc90196B |
0.763 |
|
2019 |
Maji B, Gangopadhyay SA, Lee M, Shi M, Wu P, Heler R, Mok B, Lim D, Siriwardena SU, Paul B, Dančík V, Vetere A, Mesleh MF, Marraffini LA, Liu DR, ... ... Choudhary A, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 177: 1067-1079.e19. PMID 31051099 DOI: 10.1016/J.Cell.2019.04.009 |
0.794 |
|
2019 |
Cox KJ, Subramanian HKK, Samaniego CC, Franco E, Choudhary A. A universal method for sensitive and cell-free detection of CRISPR-associated nucleases. Chemical Science. 10: 2653-2662. PMID 30996981 DOI: 10.1039/C8Sc03426E |
0.791 |
|
2019 |
Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R. A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9. Angewandte Chemie (International Ed. in English). PMID 30834641 DOI: 10.1002/Anie.201900788 |
0.789 |
|
2019 |
Gangopadhyay SA, Cox K, Manna D, Lim D, Maji B, Zhou Q, Choudhary A. Precision control of CRISPR-Cas9 using small molecules and light. Biochemistry. PMID 30640437 DOI: 10.1021/Acs.Biochem.8B01202 |
0.798 |
|
2016 |
Vasta JD, Choudhary A, Jensen KH, McGrath NA, Raines RT. Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond. Biochemistry. PMID 28001367 DOI: 10.1021/Acs.Biochem.6B00976 |
0.759 |
|
2016 |
Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224 |
0.812 |
|
2015 |
Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dan?ík V, Ciarlo C, Paulk J, et al. Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling. Journal of the American Chemical Society. 137: 7929-34. PMID 26042473 DOI: 10.1021/Jacs.5B04284 |
0.555 |
|
2015 |
Choudhary A, Kamer KJ, Shoulders MD, Raines RT. 4-ketoproline: An electrophilic proline analog for bioconjugation. Biopolymers. 104: 110-5. PMID 25656588 DOI: 10.1002/Bip.22620 |
0.693 |
|
2014 |
Choudhary A, Newberry RW, Raines RT. n→π* interactions engender chirality in carbonyl groups. Organic Letters. 16: 3421-3. PMID 24926562 DOI: 10.1021/Ol5012967 |
0.731 |
|
2014 |
Choudhary A, Hu He K, Mertins P, Udeshi ND, Dan?ík V, Fomina-Yadlin D, Kubicek S, Clemons PA, Schreiber SL, Carr SA, Wagner BK. Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming. Plos One. 9: e95194. PMID 24759943 DOI: 10.1371/Journal.Pone.0095194 |
0.437 |
|
2013 |
Choudhary A, Fry CG, Kamer KJ, Raines RT. An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group. Chemical Communications (Cambridge, England). 49: 8166-8. PMID 23928794 DOI: 10.1039/C3Cc44573A |
0.463 |
|
2013 |
Guzei IA, Choudhary A, Raines RT. Pyramidalization of a carbonyl C atom in (2S)-N-(seleno-acet-yl)proline methyl ester. Acta Crystallographica. Section E, Structure Reports Online. 69: o805-6. PMID 23723945 DOI: 10.1107/S1600536813011112 |
0.439 |
|
2013 |
Kamer KJ, Choudhary A, Raines RT. Intimate interactions with carbonyl groups: dipole-dipole or n→π*? The Journal of Organic Chemistry. 78: 2099-103. PMID 23163960 DOI: 10.1021/Jo302265K |
0.436 |
|
2012 |
Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW, Carroll P, Raines RT. Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. The Journal of Organic Chemistry. 77: 5331-44. PMID 22607128 DOI: 10.1021/Jo300700A |
0.672 |
|
2012 |
Choudhary A, Kamer KJ, Raines RT. A conserved interaction with the chromophore of fluorescent proteins. Protein Science : a Publication of the Protein Society. 21: 171-7. PMID 22057893 DOI: 10.1002/Pro.762 |
0.481 |
|
2011 |
Choudhary A, Kamer KJ, Raines RT. An n→π* interaction in aspirin: implications for structure and reactivity. The Journal of Organic Chemistry. 76: 7933-7. PMID 21842865 DOI: 10.1021/Jo201389D |
0.461 |
|
2011 |
Choudhary A, Raines RT. An evaluation of peptide-bond isosteres. Chembiochem : a European Journal of Chemical Biology. 12: 1801-7. PMID 21751326 DOI: 10.1002/Cbic.201100272 |
0.469 |
|
2011 |
Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross CW, Choudhary A, Shoulders MD, Raines RT. Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. The Journal of Organic Chemistry. 76: 3626-34. PMID 21500838 DOI: 10.1021/Jo200117P |
0.673 |
|
2011 |
Choudhary A, Raines RT. Signature of n→π* interactions in α-helices. Protein Science : a Publication of the Protein Society. 20: 1077-81. PMID 21442680 DOI: 10.1002/Pro.627 |
0.452 |
|
2011 |
Choudhary A, Pua KH, Raines RT. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids. 41: 181-6. PMID 20221839 DOI: 10.1007/S00726-010-0504-8 |
0.447 |
|
2010 |
Choudhary A, Fry CG, Raines RT. Modulation of an n→π* interaction with α-fluoro groups. Arkivoc : Free Online Journal of Organic Chemistry / Arkat-Usa, Inc. 2010: 251-262. PMID 21643549 DOI: 10.3998/Ark.5550190.0011.817 |
0.474 |
|
2010 |
Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The aberrance of the 4S diastereomer of 4-hydroxyproline. Journal of the American Chemical Society. 132: 10857-65. PMID 20681719 DOI: 10.1021/Ja103082Y |
0.765 |
|
2010 |
Bartlett GJ, Choudhary A, Raines RT, Woolfson DN. n-->pi* interactions in proteins. Nature Chemical Biology. 6: 615-20. PMID 20622857 DOI: 10.1038/Nchembio.406 |
0.482 |
|
2010 |
Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A stereoelectronic effect in prebiotic nucleotide synthesis. Acs Chemical Biology. 5: 655-7. PMID 20499895 DOI: 10.1021/Cb100093G |
0.472 |
|
2010 |
Jakobsche CE, Choudhary A, Miller SJ, Raines RT. n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. Journal of the American Chemical Society. 132: 6651-3. PMID 20420451 DOI: 10.1021/Ja100931Y |
0.464 |
|
2010 |
Choudhary A, Fry CG, Raines RT. Modulation of an np* interaction with a-fluoro groups Arkivoc. 2010: 251-262. |
0.335 |
|
2009 |
Krow GR, Edupuganti R, Gandla D, Choudhary A, Lin G, Sonnet PE, DeBrosse C, Ross CW, Cannon KC, Raines RT. 5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: a nucleophilic displacement route. The Journal of Organic Chemistry. 74: 8232-42. PMID 19799411 DOI: 10.1021/Jo901725K |
0.427 |
|
2009 |
Choudhary A, Gandla D, Krow GR, Raines RT. Nature of amide carbonyl--carbonyl interactions in proteins. Journal of the American Chemical Society. 131: 7244-6. PMID 19469574 DOI: 10.1021/Ja901188Y |
0.485 |
|
2007 |
Prasad KR, Penchalaiah K, Choudhary A, Anbarasan P. Stereoselective synthesis of (-)-microcarpalide Tetrahedron Letters. 48: 309-311. DOI: 10.1016/J.Tetlet.2006.11.027 |
0.666 |
|
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