Amit Choudhary - Publications

Harvard University, Cambridge, MA, United States 

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kahraman S, Manna D, Dirice E, Maji B, Small J, Wagner BK, Choudhary A, Kulkarni RN. Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells. Life Science Alliance. 4. PMID 33514654 DOI: 10.26508/lsa.202000840  1
2020 Sreekanth V, Zhou Q, Kokkonda P, Bermudez-Cabrera HC, Lim D, Law BK, Holmes BR, Chaudhary SK, Pergu R, Leger BS, Walker JA, Gifford DK, Sherwood RI, Choudhary A. Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes. Acs Central Science. 6: 2228-2237. PMID 33376784 DOI: 10.1021/acscentsci.0c00129  0.96
2020 Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen CH, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, et al. Core commitments for field trials of gene drive organisms. Science (New York, N.Y.). 370: 1417-1419. PMID 33335055 DOI: 10.1126/science.abd1908  0.48
2020 Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. clustered regularly interspaced short palindromic repeat-Chemical and optical control of CRISPR-associated nucleases. Current Opinion in Chemical Biology. 60: 113-121. PMID 33253976 DOI: 10.1016/j.cbpa.2020.10.003  0.88
2020 Yang K, Lee M, Jones PA, Liu SS, Zhou A, Xu J, Sreekanth V, Wu JLY, Vo L, Lee EA, Pop R, Lee Y, Wagner BK, Melton DA, Choudhary A, et al. A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells. Science Advances. 6. PMID 33208361 DOI: 10.1126/sciadv.abc3207  1
2020 Lim D, Sreekanth V, Cox KJ, Law BK, Wagner BK, Karp JM, Choudhary A. Engineering designer beta cells with a CRISPR-Cas9 conjugation platform. Nature Communications. 11: 4043. PMID 32792475 DOI: 10.1038/s41467-020-17725-0  1
2020 Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Phosphorylation-Inducing Chimeric Small Molecules. Journal of the American Chemical Society. PMID 32787262 DOI: 10.1021/jacs.0c05537  0.88
2020 López Del Amo V, Leger BS, Cox KJ, Gill S, Bishop AL, Scanlon GD, Walker JA, Gantz VM, Choudhary A. Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives. Cell Reports. 31: 107841. PMID 32610142 DOI: 10.1016/j.celrep.2020.107841  0.96
2020 Modell AE, Siriwardena SU, Choudhary A. A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems. Biochemistry. 59: 1869-1870. PMID 32403926 DOI: 10.1021/acs.biochem.0c00273  0.88
2020 Lee M, Maji B, Manna D, Kahraman S, Elgamal RM, Small J, Kokkonda P, Vetere A, Goldberg JM, Lippard SJ, Kulkarni RN, Wagner BK, Choudhary A. Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells. Journal of the American Chemical Society. PMID 32175731 DOI: 10.1021/jacs.0c00099  1
2019 Maji B, Gangopadhyay SA, Lee M, Shi M, Wu P, Heler R, Mok B, Lim D, Siriwardena SU, Paul B, Dančík V, Vetere A, Mesleh MF, Marraffini LA, Liu DR, ... ... Choudhary A, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 177: 1067-1079.e19. PMID 31051099 DOI: 10.1016/j.cell.2019.04.009  1
2019 Cox KJ, Subramanian HKK, Samaniego CC, Franco E, Choudhary A. A universal method for sensitive and cell-free detection of CRISPR-associated nucleases. Chemical Science. 10: 2653-2662. PMID 30996981 DOI: 10.1039/c8sc03426e  0.96
2019 Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R. A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9. Angewandte Chemie (International Ed. in English). PMID 30834641 DOI: 10.1002/anie.201900788  0.96
2019 Gangopadhyay SA, Cox K, Manna D, Lim D, Maji B, Zhou Q, Choudhary A. Precision control of CRISPR-Cas9 using small molecules and light. Biochemistry. PMID 30640437 DOI: 10.1021/acs.biochem.8b01202  0.96
2018 Choudhary A, George TF, Li G. Conjugation of Nanomaterials and Nematic Liquid Crystals for Futuristic Applications and Biosensors. Biosensors. 8. PMID 30011909 DOI: 10.3390/bios8030069  1
2016 Vasta JD, Choudhary A, Jensen KH, McGrath NA, Raines RT. Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond. Biochemistry. PMID 28001367 DOI: 10.1021/acs.biochem.6b00976  1
2016 Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/nchembio.2224  0.96
2015 Schmeisser F, Jing X, Joshi M, Vasudevan A, Soto J, Li X, Choudhary A, Baichoo N, Resnick J, Ye Z, McCormick W, Weir JP. A Novel Approach for Preparation of the Antisera Reagent for Potency Determination of Inactivated H7N9 Influenza Vaccines. Influenza and Other Respiratory Viruses. PMID 26616263 DOI: 10.1111/irv.12365  0.88
2015 Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dan?ík V, Ciarlo C, Paulk J, et al. Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling. Journal of the American Chemical Society. 137: 7929-34. PMID 26042473 DOI: 10.1021/jacs.5b04284  1
2015 Choudhary A, Kamer KJ, Shoulders MD, Raines RT. 4-ketoproline: An electrophilic proline analog for bioconjugation. Biopolymers. 104: 110-5. PMID 25656588 DOI: 10.1002/bip.22620  1
2015 Gopalan H, Chandar DDJ, Pillamarri NR, Mengzhao G, Jaiman RK, Ma P, Xu H, Choudhary A, Hussain A. Numerical investigation of flow interference effects in fixed and vibrating tandem square columns using hybrid RANS-LES models Proceedings of the International Conference On Offshore Mechanics and Arctic Engineering - Omae. 2. DOI: 10.1115/OMAE2015-41659  0.6
2015 Gopalan H, Ma P, Xu H, Choudhary A, Hussain A, Jaiman RK. Hybrid RANS-LES formulations for wake interference physics in tandem cylinders and multi-column floaters Proceedings of the International Conference On Offshore Mechanics and Arctic Engineering - Omae. 2. DOI: 10.1115/OMAE2015-41145  0.6
2015 Xu H, Liu R, Choudhary A, Chen W. A Machine Learning-Based Design Representation Method for Designing Heterogeneous Microstructures Journal of Mechanical Design, Transactions of the Asme. 137. DOI: 10.1115/1.4029768  0.6
2015 Xie Y, Cheng Y, Agrawal A, Choudhary A. Estimating online user location distribution without GPS location Ieee International Conference On Data Mining Workshops, Icdmw. 2015: 936-943. DOI: 10.1109/ICDMW.2014.30  0.6
2015 Cheng Y, Choudhary A, Wang J, Pankanti S, Liu H. Dual uncertainty minimization regularization and its applications on heterogeneous data Ieee International Conference On Data Mining Workshops, Icdmw. 2015: 1163-1170. DOI: 10.1109/ICDMW.2014.138  0.6
2015 Cheng Y, Agrawal A, Choudhary A, Liu H, Zhang T. Social Role Identification via Dual Uncertainty Minimization Regularization Proceedings - Ieee International Conference On Data Mining, Icdm. 2015: 767-772. DOI: 10.1109/ICDM.2014.31  0.6
2015 Jin C, Fu Q, Wang H, Hendrix W, Chen Z, Agrawal A, Banerjee A, Choudhary A. Running MAP inference on million node graphical models: A high performance computing perspective Proceedings - 2015 Ieee/Acm 15th International Symposium On Cluster, Cloud, and Grid Computing, Ccgrid 2015. 565-575. DOI: 10.1109/CCGrid.2015.35  0.6
2015 Jin C, Liu R, Hendrix W, Agrawal A, Choudhary A, Chen Z. A scalable hierarchical clustering algorithm using spark Proceedings - 2015 Ieee 1st International Conference On Big Data Computing Service and Applications, Bigdataservice 2015. 418-427. DOI: 10.1109/BigDataService.2015.67  0.4
2015 Palsetia D, Patwary MMA, Hendrix W, Agrawal A, Choudhary A. Clique guided community detection Proceedings - 2014 Ieee International Conference On Big Data, Ieee Big Data 2014. 500-509. DOI: 10.1109/BigData.2014.7004267  0.6
2015 Pattabiraman B, Patwary MMA, Gebremedhin AH, Liao WK, Choudhary A. Fast algorithms for the maximum clique problem on massive graphs with applications to overlapping community detection Internet Mathematics. 11: 421-448. DOI: 10.1080/15427951.2014.986778  0.6
2015 Kim SJ, Zhang Y, Son SW, Kandemir M, Liao Wk, Thakur R, Choudhary A. IOPro: a parallel I/O profiling and visualization framework for high-performance storage systems Journal of Supercomputing. 71: 840-870. DOI: 10.1007/s11227-014-1329-0  0.6
2015 Jin C, Chen Z, Hendrix W, Agrawal A, Choudhary A. Incremental, distributed single-linkage hierarchical clustering algorithm using MapReduce Simulation Series. 47: 83-92.  0.6
2015 Xie Y, Daga P, Cheng Y, Zhang K, Agrawal A, Choudhary A. Reducing infrequent-token perplexity via variational corpora Acl-Ijcnlp 2015 - 53rd Annual Meeting of the Association For Computational Linguistics and the 7th International Joint Conference On Natural Language Processing of the Asian Federation of Natural Language Processing, Proceedings of the Conference. 2: 609-615.  0.6
2014 Choudhary A, Li G. Anisotropic shift of surface plasmon resonance of gold nanoparticles doped in nematic liquid crystal. Optics Express. 22: 24348-57. PMID 25322010 DOI: 10.1364/OE.22.024348  1
2014 Choudhary A, Newberry RW, Raines RT. n→π* interactions engender chirality in carbonyl groups. Organic Letters. 16: 3421-3. PMID 24926562 DOI: 10.1021/ol5012967  1
2014 Choudhary A, Hu He K, Mertins P, Udeshi ND, Dan?ík V, Fomina-Yadlin D, Kubicek S, Clemons PA, Schreiber SL, Carr SA, Wagner BK. Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming. Plos One. 9: e95194. PMID 24759943 DOI: 10.1371/journal.pone.0095194  1
2014 Vetere A, Choudhary A, Burns SM, Wagner BK. Targeting the pancreatic β-cell to treat diabetes. Nature Reviews. Drug Discovery. 13: 278-89. PMID 24525781 DOI: 10.1038/nrd4231  1
2014 Gao H, Yang Y, Bu K, Chen Y, Downey D, Lee K, Choudhary A. Spam ain t as diverse as it seems: Throttling OSN spam with templates underneath Acm International Conference Proceeding Series. 2014: 76-85. DOI: 10.1145/2664243.2664251  0.32
2014 Harenberg S, Seay RG, Ranshous S, Padmanabhan K, Harlalka JK, Schendel ER, O'Brien MP, Chirkova RY, Hendrix W, Choudhary AN, Kumar V, Doraiswamy M, Samatova NF. Memory-efficient query-driven community detection with application to complex disease associations Siam International Conference On Data Mining 2014, Sdm 2014. 2: 1010-1018. DOI: 10.1137/1.9781611973440.115  0.4
2014 Chen Z, Son SW, Hendrix W, Agrawal A, Liao WK, Choudhary A. NUMARCK: Machine Learning Algorithm for Resiliency and Checkpointing International Conference For High Performance Computing, Networking, Storage and Analysis, Sc. 2015: 733-744. DOI: 10.1109/SC.2014.65  0.6
2014 Xie Y, Chen Z, Zhang K, Cheng Y, Honbo DK, Agrawal A, Choudhary AN. MuSES: Multilingual sentiment elicitation system for social media data Ieee Intelligent Systems. 29: 34-42. DOI: 10.1109/MIS.2013.52  0.6
2014 Xie Y, Chen Z, Palsetia D, Agrawal A, Choudhary A. Indexing bipartite memberships in web graphs Asonam 2014 - Proceedings of the 2014 Ieee/Acm International Conference On Advances in Social Networks Analysis and Mining. 166-173. DOI: 10.1109/ASONAM.2014.6921578  0.6
2014 Meredig B, Agrawal A, Kirklin S, Saal JE, Doak JW, Thompson A, Zhang K, Choudhary A, Wolverton C. Combinatorial screening for new materials in unconstrained composition space with machine learning Physical Review B - Condensed Matter and Materials Physics. 89. DOI: 10.1103/PhysRevB.89.094104  0.6
2013 Choudhary A, Fry CG, Kamer KJ, Raines RT. An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group. Chemical Communications (Cambridge, England). 49: 8166-8. PMID 23928794 DOI: 10.1039/c3cc44573a  1
2013 Guzei IA, Choudhary A, Raines RT. Pyramidalization of a carbonyl C atom in (2S)-N-(seleno-acet-yl)proline methyl ester. Acta Crystallographica. Section E, Structure Reports Online. 69: o805-6. PMID 23723945 DOI: 10.1107/S1600536813011112  1
2013 Kamer KJ, Choudhary A, Raines RT. Intimate interactions with carbonyl groups: dipole-dipole or n→π*? The Journal of Organic Chemistry. 78: 2099-103. PMID 23163960 DOI: 10.1021/jo302265k  1
2013 Choudhury HA, Choudhary A, Sivakumar M, Moholkar VS. Mechanistic investigation of the sonochemical synthesis of zinc ferrite. Ultrasonics Sonochemistry. 20: 294-302. PMID 22805260 DOI: 10.1016/j.ultsonch.2012.06.006  1
2012 Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW, Carroll P, Raines RT. Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. The Journal of Organic Chemistry. 77: 5331-44. PMID 22607128 DOI: 10.1021/jo300700a  1
2012 Choudhary A, Kamer KJ, Raines RT. A conserved interaction with the chromophore of fluorescent proteins. Protein Science : a Publication of the Protein Society. 21: 171-7. PMID 22057893 DOI: 10.1002/pro.762  1
2011 Choudhary A, Kamer KJ, Raines RT. An n→π* interaction in aspirin: implications for structure and reactivity. The Journal of Organic Chemistry. 76: 7933-7. PMID 21842865 DOI: 10.1021/jo201389d  1
2011 Choudhary A, Raines RT. An evaluation of peptide-bond isosteres. Chembiochem : a European Journal of Chemical Biology. 12: 1801-7. PMID 21751326 DOI: 10.1002/cbic.201100272  1
2011 Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross CW, Choudhary A, Shoulders MD, Raines RT. Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. The Journal of Organic Chemistry. 76: 3626-34. PMID 21500838 DOI: 10.1021/jo200117p  1
2011 Choudhary A, Raines RT. Signature of n→π* interactions in α-helices. Protein Science : a Publication of the Protein Society. 20: 1077-81. PMID 21442680 DOI: 10.1002/pro.627  1
2011 Choudhary A, Pua KH, Raines RT. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids. 41: 181-6. PMID 20221839 DOI: 10.1007/s00726-010-0504-8  1
2010 Choudhary A, Fry CG, Raines RT. Modulation of an n→π* interaction with α-fluoro groups. Arkivoc : Free Online Journal of Organic Chemistry / Arkat-Usa, Inc. 2010: 251-262. PMID 21643549 DOI: 10.3998/ark.5550190.0011.817  1
2010 Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The aberrance of the 4S diastereomer of 4-hydroxyproline. Journal of the American Chemical Society. 132: 10857-65. PMID 20681719 DOI: 10.1021/ja103082y  1
2010 Bartlett GJ, Choudhary A, Raines RT, Woolfson DN. n-->pi* interactions in proteins. Nature Chemical Biology. 6: 615-20. PMID 20622857 DOI: 10.1038/nchembio.406  1
2010 Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A stereoelectronic effect in prebiotic nucleotide synthesis. Acs Chemical Biology. 5: 655-7. PMID 20499895 DOI: 10.1021/cb100093g  1
2010 Jakobsche CE, Choudhary A, Miller SJ, Raines RT. n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. Journal of the American Chemical Society. 132: 6651-3. PMID 20420451 DOI: 10.1021/ja100931y  1
2010 Choudhary A, Fry CG, Raines RT. Modulation of an np* interaction with a-fluoro groups Arkivoc. 2010: 251-262.  1
2009 Krow GR, Edupuganti R, Gandla D, Choudhary A, Lin G, Sonnet PE, DeBrosse C, Ross CW, Cannon KC, Raines RT. 5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: a nucleophilic displacement route. The Journal of Organic Chemistry. 74: 8232-42. PMID 19799411 DOI: 10.1021/jo901725k  1
2009 Choudhary A, Gandla D, Krow GR, Raines RT. Nature of amide carbonyl--carbonyl interactions in proteins. Journal of the American Chemical Society. 131: 7244-6. PMID 19469574 DOI: 10.1021/ja901188y  1
2007 Prasad KR, Penchalaiah K, Choudhary A, Anbarasan P. Stereoselective synthesis of (-)-microcarpalide Tetrahedron Letters. 48: 309-311. DOI: 10.1016/j.tetlet.2006.11.027  1
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