Michael D. Toney, Ph.D. - Publications

1994-1999 Chemistry Albert Einstein College of Medicine of Yeshiva University, NY, United States 
 1999- Chemistry University of California, Davis, Davis, CA 

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Valenzuela-Chavira I, Corona-Martinez DO, Garcia-Orozco KD, Beltran-Torres M, Sanchez-Lopez F, Arvizu-Flores AA, Sugich-Miranda R, Lopez-Zavala AA, Robles-Zepeda RE, Islas-Osuna MA, Ochoa-Leyva A, Toney MD, Serrano-Posada H, Sotelo-Mundo RR. A Novel Glutathione -Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS Shrimp Pathogen. Toxins. 13. PMID 34564668 DOI: 10.3390/toxins13090664  0.311
2020 Peng Z, Peralta MDR, Cox DL, Toney MD. Bottom-up synthesis of protein-based nanomaterials from engineered β-solenoid proteins. Plos One. 15: e0229319. PMID 32084222 DOI: 10.1371/Journal.Pone.0229319  0.358
2019 Wang Y, Chung DH, Monteleone LR, Li J, Chiang Y, Toney MD, Beal PA. RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells. Nucleic Acids Research. PMID 31552420 DOI: 10.1093/Nar/Gkz815  0.333
2019 Toney MD. Carbon Acidity in Enzyme Active Sites. Frontiers in Bioengineering and Biotechnology. 7: 25. PMID 30838206 DOI: 10.3389/Fbioe.2019.00025  0.512
2017 Peng Z, Parker AS, Peralta MDR, Ravikumar KM, Cox DL, Toney MD. High Tensile Strength of Engineered β-Solenoid Fibrils via Sonication and Pulling. Biophysical Journal. 113: 1945-1955. PMID 29117519 DOI: 10.1016/J.Bpj.2017.09.003  0.386
2017 Peng Z, Peralta MD, Toney MD. Extraordinarily Stable Amyloid Fibrils Engineered from Structurally Defined β-Solenoid Proteins. Biochemistry. PMID 29064686 DOI: 10.1021/Acs.Biochem.7B00364  0.41
2017 Chung DH, Potter SC, Tanomrat AC, Ravikumar KM, Toney MD. Site-directed mutant libraries for isolating minimal mutations yielding functional changes. Protein Engineering, Design & Selection : Peds. 1-11. PMID 28338893 DOI: 10.1093/Protein/Gzx013  0.335
2016 Desai SH, Koryakina I, Case AE, Toney MD, Atsumi S. Biological conversion of gaseous alkenes to liquid chemicals. Metabolic Engineering. PMID 27424209 DOI: 10.1016/J.Ymben.2016.07.002  0.685
2015 Culbertson JE, Chung Dh, Ziebart KT, Espiritu E, Toney MD. Conversion of aminodeoxychorismate synthase into anthranilate synthase with Janus mutations: mechanism of pyruvate elimination catalyzed by chorismate enzymes. Biochemistry. 54: 2372-84. PMID 25710100 DOI: 10.1021/Acs.Biochem.5B00013  0.774
2015 Taylor JL, Price JE, Toney MD. Directed evolution of the substrate specificity of dialkylglycine decarboxylase. Biochimica Et Biophysica Acta. 1854: 146-55. PMID 25500286 DOI: 10.1016/J.Bbapap.2014.12.003  0.489
2014 Fleischman NM, Das D, Kumar A, Xu Q, Chiu HJ, Jaroszewski L, Knuth MW, Klock HE, Miller MD, Elsliger MA, Godzik A, Lesley SA, Deacon AM, Wilson IA, Toney MD. Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome. Protein Science : a Publication of the Protein Society. 23: 1060-76. PMID 24888348 DOI: 10.1002/Pro.2493  0.483
2014 Toney MD. Aspartate aminotransferase: an old dog teaches new tricks. Archives of Biochemistry and Biophysics. 544: 119-27. PMID 24121043 DOI: 10.1016/J.Abb.2013.10.002  0.513
2013 Chan-Huot M, Dos A, Zander R, Sharif S, Tolstoy PM, Compton S, Fogle E, Toney MD, Shenderovich I, Denisov GS, Limbach HH. NMR studies of protonation and hydrogen bond states of internal aldimines of pyridoxal 5'-phosphate acid-base in alanine racemase, aspartate aminotransferase, and poly-L-lysine. Journal of the American Chemical Society. 135: 18160-75. PMID 24147985 DOI: 10.1021/Ja408988Z  0.754
2013 Toney MD. Common enzymological experiments allow free energy profile determination. Biochemistry. 52: 5952-65. PMID 23906433 DOI: 10.1021/Bi400696J  0.365
2013 Chan-Huot M, Lesot P, Pelupessy P, Duma L, Bodenhausen G, Duchambon P, Toney MD, Reddy UV, Suryaprakash N. "On-the-fly" kinetics of enzymatic racemization using deuterium NMR in DNA-based chiral oriented media. Analytical Chemistry. 85: 4694-7. PMID 23547756 DOI: 10.1021/Ac4004002  0.354
2013 Addington TA, Mertz RW, Siegel JB, Thompson JM, Fisher AJ, Filkov V, Fleischman NM, Suen AA, Zhang C, Toney MD. Janus: prediction and ranking of mutations required for functional interconversion of enzymes. Journal of Molecular Biology. 425: 1378-89. PMID 23396064 DOI: 10.1016/J.Jmb.2013.01.034  0.473
2013 Toney MD, Castro JN, Addington TA. Heavy-enzyme kinetic isotope effects on proton transfer in alanine racemase. Journal of the American Chemical Society. 135: 2509-11. PMID 23373756 DOI: 10.1021/Ja3101243  0.481
2013 Culbertson JE, Toney MD. Expression and characterization of PhzE from P. aeruginosa PAO1: aminodeoxyisochorismate synthase involved in pyocyanin and phenazine-1-carboxylate production. Biochimica Et Biophysica Acta. 1834: 240-6. PMID 23099261 DOI: 10.1016/J.Bbapap.2012.10.010  0.771
2012 Griswold WR, Castro JN, Fisher AJ, Toney MD. Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase. Journal of the American Chemical Society. 134: 8436-8. PMID 22551424 DOI: 10.1021/Ja302809E  0.651
2011 Toney MD. Pyridoxal phosphate enzymology. Biochimica Et Biophysica Acta. 1814: 1405-6. PMID 21871586 DOI: 10.1016/J.Bbapap.2011.08.007  0.377
2011 Griswold WR, Toney MD. Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate. Journal of the American Chemical Society. 133: 14823-30. PMID 21827189 DOI: 10.1021/Ja2061006  0.735
2011 Limbach HH, Chan-Huot M, Sharif S, Tolstoy PM, Shenderovich IG, Denisov GS, Toney MD. Critical hydrogen bonds and protonation states of pyridoxal 5'-phosphate revealed by NMR. Biochimica Et Biophysica Acta. 1814: 1426-37. PMID 21703367 DOI: 10.1016/J.Bbapap.2011.06.004  0.402
2011 Toney MD. Controlling reaction specificity in pyridoxal phosphate enzymes. Biochimica Et Biophysica Acta. 1814: 1407-18. PMID 21664990 DOI: 10.1016/J.Bbapap.2011.05.019  0.528
2011 Fogle EJ, Toney MD. Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates. Biochimica Et Biophysica Acta. 1814: 1113-9. PMID 21640851 DOI: 10.1016/J.Bbapap.2011.05.014  0.781
2011 Griswold WR, Fisher AJ, Toney MD. Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: internal aldimine and stable L-aspartate external aldimine. Biochemistry. 50: 5918-24. PMID 21627105 DOI: 10.1021/Bi200436Y  0.665
2010 Chan-Huot M, Sharif S, Tolstoy PM, Toney MD, Limbach HH. NMR studies of the stability, protonation States, and tautomerism of (13)C- AND (15)N-labeled aldimines of the coenzyme pyridoxal 5'-phosphate in water. Biochemistry. 49: 10818-30. PMID 21067170 DOI: 10.1021/Bi101061M  0.404
2010 Hill MP, Carroll EC, Vang MC, Addington TA, Toney MD, Larsen DS. Light-enhanced catalysis by pyridoxal phosphate-dependent aspartate aminotransferase. Journal of the American Chemical Society. 132: 16953-61. PMID 21058708 DOI: 10.1021/Ja107054X  0.445
2010 Mascal M, Hafezi N, Toney MD. 1,4,7-Trimethyloxatriquinane: S(N)2 reaction at tertiary carbon. Journal of the American Chemical Society. 132: 10662-4. PMID 20681692 DOI: 10.1021/Ja103880C  0.347
2010 Fogle EJ, Toney MD. Mutational analysis of substrate interactions with the active site of dialkylglycine decarboxylase. Biochemistry. 49: 6485-93. PMID 20540501 DOI: 10.1021/Bi100648W  0.778
2010 Ziebart KT, Dixon SM, Avila B, El-Badri MH, Guggenheim KG, Kurth MJ, Toney MD. Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design. Journal of Medicinal Chemistry. 53: 3718-29. PMID 20359225 DOI: 10.1021/Jm100158V  0.392
2010 Ziebart KT, Toney MD. Nucleophile specificity in anthranilate synthase, aminodeoxychorismate synthase, isochorismate synthase, and salicylate synthase. Biochemistry. 49: 2851-9. PMID 20170126 DOI: 10.1021/Bi100021X  0.483
2010 Griswold WR, Toney MD. Chemoenzymatic synthesis of 1-deaza-pyridoxal 5'-phosphate. Bioorganic & Medicinal Chemistry Letters. 20: 1352-4. PMID 20097067 DOI: 10.1016/J.Bmcl.2010.01.002  0.665
2010 Chan-Huot M, Niether C, Sharif S, Tolstoy PM, Toney MD, Limbach HH. NMR studies of the protonation states of pyridoxal-5′-phosphate in water Journal of Molecular Structure. 976: 282-289. DOI: 10.1016/J.Molstruc.2010.03.032  0.379
2008 Hill MP, Carroll EC, Toney MD, Larsen DS. Rapid photodynamics of vitamin B6 coenzyme pyridoxal 5'-phosphate and its Schiff bases in solution. The Journal of Physical Chemistry. B. 112: 5867-73. PMID 18416573 DOI: 10.1021/Jp7117345  0.426
2007 Spies MA, Toney MD. Intrinsic primary and secondary hydrogen kinetic isotope effects for alanine racemase from global analysis of progress curves. Journal of the American Chemical Society. 129: 10678-85. PMID 17691728 DOI: 10.1021/Ja067643K  0.391
2007 Sharif S, Fogle E, Toney MD, Denisov GS, Shenderovich IG, Buntkowsky G, Tolstoy PM, Huot MC, Limbach HH. NMR localization of protons in critical enzyme hydrogen bonds. Journal of the American Chemical Society. 129: 9558-9. PMID 17628065 DOI: 10.1021/Ja0728223  0.758
2007 Sharif S, Denisov GS, Toney MD, Limbach HH. NMR studies of coupled low- and high-barrier hydrogen bonds in pyridoxal-5'-phosphate model systems in polar solution. Journal of the American Chemical Society. 129: 6313-27. PMID 17455937 DOI: 10.1021/Ja070296+  0.402
2007 Sharif S, Huot MC, Tolstoy PM, Toney MD, Jonsson KH, Limbach HH. 15N nuclear magnetic resonance studies of acid-base properties of pyridoxal-5'-phosphate aldimines in aqueous solution. The Journal of Physical Chemistry. B. 111: 3869-76. PMID 17388551 DOI: 10.1021/Jp067334G  0.395
2007 Sharif S, Schagen D, Toney MD, Limbach HH. Coupling of functional hydrogen bonds in pyridoxal-5'-phosphate-enzyme model systems observed by solid-state NMR spectroscopy. Journal of the American Chemical Society. 129: 4440-55. PMID 17371021 DOI: 10.1021/Ja066240H  0.404
2007 Golubev NS, Smirnov SN, Tolstoy PM, Sharif S, Toney MD, Denisov GS, Limbach HH. Observation by NMR of the tautomerism of an intramolecular OHOHN-charge relay chain in a model Schiff base Journal of Molecular Structure. 844: 319-327. DOI: 10.1016/J.Molstruc.2007.04.015  0.396
2007 Spies MA, Toney MD. Multiple Hydrogen Transfers in Enzyme Action Hydrogen-Transfer Reactions. 3: 1139-1170. DOI: 10.1002/9783527611546.ch36  0.31
2006 Dixon S, Ziebart KT, He Z, Jeddeloh M, Yoo CL, Wang X, Lehman A, Lam KS, Toney MD, Kurth MJ. Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design. Journal of Medicinal Chemistry. 49: 7413-26. PMID 17149871 DOI: 10.1021/Jm0609869  0.469
2006 Sharif S, Powell DR, Schagen D, Steiner T, Toney MD, Fogle E, Limbach HH. X-ray crystallographic structures of enamine and amine Schiff bases of pyridoxal and its 1:1 hydrogen-bonded complexes with benzoic acid derivatives: evidence for coupled inter- and intramolecular proton transfer. Acta Crystallographica. Section B, Structural Science. 62: 480-7. PMID 16710068 DOI: 10.1107/S0108768105040590  0.734
2006 Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. Journal of Medicinal Chemistry. 49: 2388-97. PMID 16610782 DOI: 10.1021/Jm050701C  0.489
2006 He Z, Toney MD. Direct detection and kinetic analysis of covalent intermediate formation in the 4-amino-4-deoxychorismate synthase catalyzed reaction. Biochemistry. 45: 5019-28. PMID 16605270 DOI: 10.1021/Bi052216P  0.659
2006 Sharif S, Denisov GS, Toney MD, Limbach HH. NMR studies of solvent-assisted proton transfer in a biologically relevant Schiff base: toward a distinction of geometric and equilibrium H-bond isotope effects. Journal of the American Chemical Society. 128: 3375-87. PMID 16522119 DOI: 10.1021/Ja056251V  0.405
2006 Schnackerz KD, Keller J, Phillips RS, Toney MD. Ionization state of pyridoxal 5'-phosphate in D-serine dehydratase, dialkylglycine decarboxylase and tyrosine phenol-lyase and the influence of monovalent cations as inferred by 31P NMR spectroscopy. Biochimica Et Biophysica Acta. 1764: 230-8. PMID 16290167 DOI: 10.1016/J.Bbapap.2005.10.009  0.392
2005 Fogle EJ, Liu W, Woon ST, Keller JW, Toney MD. Role of Q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase. Biochemistry. 44: 16392-404. PMID 16342932 DOI: 10.1021/Bi051475B  0.791
2005 Liu W, Peterson PE, Langston JA, Jin X, Zhou X, Fisher AJ, Toney MD. Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry. 44: 2982-92. PMID 15723541 DOI: 10.1021/Bi048657A  0.518
2005 Toney MD. Reaction specificity in pyridoxal phosphate enzymes. Archives of Biochemistry and Biophysics. 433: 279-87. PMID 15581583 DOI: 10.1016/J.Abb.2004.09.037  0.52
2005 Foltyn VN, Bendikov I, De Miranda J, Panizzutti R, Dumin E, Shleper M, Li P, Toney MD, Kartvelishvily E, Wolosker H. Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity. The Journal of Biological Chemistry. 280: 1754-63. PMID 15536068 DOI: 10.1074/Jbc.M405726200  0.499
2004 Liu W, Peterson PE, Carter RJ, Zhou X, Langston JA, Fisher AJ, Toney MD. Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry. 43: 10896-905. PMID 15323550 DOI: 10.1021/Bi049218E  0.625
2004 Tu SL, Gunn A, Toney MD, Britt RD, Lagarias JC. Biliverdin reduction by cyanobacterial phycocyanobilin:ferredoxin oxidoreductase (PcyA) proceeds via linear tetrapyrrole radical intermediates. Journal of the American Chemical Society. 126: 8682-93. PMID 15250720 DOI: 10.1021/Ja049280Z  0.329
2004 Spies MA, Woodward JJ, Watnik MR, Toney MD. Alanine racemase free energy profiles from global analyses of progress curves. Journal of the American Chemical Society. 126: 7464-75. PMID 15198593 DOI: 10.1021/Ja049579H  0.366
2004 Liu W, Toney MD. Kinetic and thermodynamic analysis of the interaction of cations with dialkylglycine decarboxylase. Biochemistry. 43: 4998-5010. PMID 15109259 DOI: 10.1021/Bi035854L  0.536
2004 He Z, Stigers Lavoie KD, Bartlett PA, Toney MD. Conservation of mechanism in three chorismate-utilizing enzymes. Journal of the American Chemical Society. 126: 2378-85. PMID 14982443 DOI: 10.1021/Ja0389927  0.659
2003 Christenson SD, Wu W, Spies MA, Shen B, Toney MD. Kinetic analysis of the 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. Biochemistry. 42: 12708-18. PMID 14580219 DOI: 10.1021/Bi035223R  0.396
2003 Zhou X, Medhekar R, Toney MD. A continuous-flow system for high-precision kinetics using small volumes. Analytical Chemistry. 75: 3681-7. PMID 14572030 DOI: 10.1021/Ac034068J  0.345
2003 Christenson SD, Liu W, Toney MD, Shen B. A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. Journal of the American Chemical Society. 125: 6062-3. PMID 12785829 DOI: 10.1021/Ja034609M  0.539
2003 Spies MA, Toney MD. Multiple hydrogen kinetic isotope effects for enzymes catalyzing exchange with solvent: application to alanine racemase. Biochemistry. 42: 5099-107. PMID 12718553 DOI: 10.1021/Bi0274064  0.504
2002 Liu W, Rogers CJ, Fisher AJ, Toney MD. Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition. Biochemistry. 41: 12320-8. PMID 12369820 DOI: 10.1021/Bi026318G  0.524
2001 Zabinski RF, Toney MD. Metal ion inhibition of nonenzymatic pyridoxal phosphate catalyzed decarboxylation and transamination. Journal of the American Chemical Society. 123: 193-8. PMID 11456503 DOI: 10.1021/Ja0026354  0.413
2001 Sánchez C, Du L, Edwards DJ, Toney MD, Shen B. Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin. Chemistry & Biology. 8: 725-38. PMID 11451672 DOI: 10.1016/S1074-5521(01)00047-3  0.334
2001 Toney MD. Computational studies on nonenzymatic and enzymatic pyridoxal phosphate catalyzed decarboxylations of 2-aminoisobutyrate. Biochemistry. 40: 1378-84. PMID 11170465 DOI: 10.1021/Bi0012383  0.484
2001 Zhou X, Jin X, Medhekar R, Chen X, Dieckmann T, Toney MD. Rapid kinetic and isotopic studies on dialkylglycine decarboxylase. Biochemistry. 40: 1367-77. PMID 11170464 DOI: 10.1021/Bi001237A  0.459
1999 Malashkevich VN, Strop P, Keller JW, Jansonius JN, Toney MD. Crystal structures of dialkylglycine decarboxylase inhibitor complexes. Journal of Molecular Biology. 294: 193-200. PMID 10556038 DOI: 10.1006/Jmbi.1999.3254  0.473
1999 Sun S, Toney MD. Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase. Biochemistry. 38: 4058-65. PMID 10194319 DOI: 10.1021/Bi982924T  0.436
1999 Zhou X, Toney MD. pH studies on the mechanism of the pyridoxal phosphate-dependent dialkylglycine decarboxylase. Biochemistry. 38: 311-20. PMID 9890912 DOI: 10.1021/Bi981455S  0.446
1998 Zhou X, Kay S, Toney MD. Coexisting kinetically distinguishable forms of dialkylglycine decarboxylase engendered by alkali metal ions. Biochemistry. 37: 5761-9. PMID 9548963 DOI: 10.1021/Bi973010U  0.455
1998 Sun S, Bagdassarian CK, Toney MD. Pre-steady-state kinetic analysis of the reactions of alternate substrates with dialkylglycine decarboxylase. Biochemistry. 37: 3876-85. PMID 9521708 DOI: 10.1021/Bi972056K  0.468
1998 Sun S, Zabinski RF, Toney MD. Reactions of alternate substrates demonstrate stereoelectronic control of reactivity in dialkylglycine decarboxylase. Biochemistry. 37: 3865-75. PMID 9521707 DOI: 10.1021/Bi972055S  0.484
1998 Zhou X, Toney MD. Kinetic isotope effects for dialkylglycine decarboxylase via a high- precision continuous-flow method [18] Journal of the American Chemical Society. 120: 13282-13283. DOI: 10.1021/Ja9825938  0.452
1995 Toney MD, Pascarella S, De Biase D. Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities. Protein Science : a Publication of the Protein Society. 4: 2366-74. PMID 8563634 DOI: 10.1002/pro.5560041115  0.332
1995 Toney MD, Hohenester E, Keller JW, Jansonius JN. Structural and mechanistic analysis of two refined crystal structures of the pyridoxal phosphate-dependent enzyme dialkylglycine decarboxylase. Journal of Molecular Biology. 245: 151-79. PMID 7799433 DOI: 10.1006/Jmbi.1994.0014  0.491
1993 Toney MD, Kirsch JF. Lysine 258 in aspartate aminotransferase: enforcer of the Circe effect for amino acid substrates and general-base catalyst for the 1,3-prototropic shift. Biochemistry. 32: 1471-9. PMID 8431426 DOI: 10.1021/Bi00057A010  0.634
1993 Toney MD, Hohenester E, Cowan SW, Jansonius JN. Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites. Science (New York, N.Y.). 261: 756-9. PMID 8342040 DOI: 10.1126/Science.8342040  0.372
1993 Malashkevich VN, Toney MD, Jansonius JN. Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase. Biochemistry. 32: 13451-62. PMID 7903048 DOI: 10.1021/Bi00212A010  0.514
1992 Toney MD, Kirsch JF. Brønsted analysis of aspartate aminotransferase via exogenous catalysis of reactions of an inactive mutant. Protein Science : a Publication of the Protein Society. 1: 107-19. PMID 1339023 DOI: 10.1002/Pro.5560010111  0.666
1991 Toney MD, Kirsch JF. The K258R mutant of aspartate aminotransferase stabilizes the quinonoid intermediate. The Journal of Biological Chemistry. 266: 23900-3. PMID 1748661  0.609
1991 Toney MD, Keller JW, Pauptit RA, Jaeger J, Wise MK, Sauder U, Jansonius JN. Crystallization and preliminary X-ray diffraction studies of dialkylglycine decarboxylase, a decarboxylating transaminase. Journal of Molecular Biology. 222: 873-5. PMID 1722256 DOI: 10.1016/0022-2836(91)90580-Y  0.314
1991 Toney MD, Kirsch JF. Kinetics and equilibria for the reactions of coenzymes with wild type and the Y70F mutant of Escherichia coli aspartate aminotransferase. Biochemistry. 30: 7461-6. PMID 1677270 DOI: 10.1021/Bi00244A014  0.626
1991 Toney MD, Kirsch JF. Tyrosine 70 fine-tunes the catalytic efficiency of aspartate aminotransferase. Biochemistry. 30: 7456-61. PMID 1677269 DOI: 10.1021/Bi00244A013  0.632
1990 Kirsch JF, Toney MD. Brønsted analysis of enzymatic proton transfer reactions through site-directed mutagenesis. Annals of the New York Academy of Sciences. 585: 48-57. PMID 2162646 DOI: 10.1111/J.1749-6632.1990.Tb28040.X  0.583
1989 Julin DA, Wiesinger H, Toney MD, Kirsch JF. Estimation of free energy barriers in the cytoplasmic and mitochondrial aspartate aminotransferase reactions probed by hydrogen-exchange kinetics of C alpha-labeled amino acids with solvent. Biochemistry. 28: 3815-21. PMID 2665809 DOI: 10.1021/Bi00435A029  0.62
1989 Toney MD, Kirsch JF. Direct Brønsted analysis of the restoration of activity to a mutant enzyme by exogenous amines. Science (New York, N.Y.). 243: 1485-8. PMID 2538921 DOI: 10.1126/Science.2538921  0.679
1989 Smith DL, Almo SC, Toney MD, Ringe D. 2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli. Biochemistry. 28: 8161-7. PMID 2513875 DOI: 10.1021/Bi00446A030  0.428
1987 Toney MD, Kirsch JF. Tyrosine 70 increases the coenzyme affinity of aspartate aminotransferase. A site-directed mutagenesis study. The Journal of Biological Chemistry. 262: 12403-5. PMID 3305507  0.621
Show low-probability matches.