Year |
Citation |
Score |
2022 |
Knerr PJ, Mowery SA, Douros JD, Premdjee B, Hjøllund KR, He Y, Kruse Hansen AM, Olsen AK, Perez-Tilve D, DiMarchi RD, Finan B. Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice. Molecular Metabolism. 101533. PMID 35809773 DOI: 10.1016/j.molmet.2022.101533 |
0.351 |
|
2014 |
Huang Y, Reis ES, Knerr PJ, van der Donk WA, Ricklin D, Lambris JD. Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin. Chemmedchem. 9: 2223-6. PMID 25056114 DOI: 10.1002/Cmdc.201402212 |
0.534 |
|
2014 |
Huang Y, Reis ES, Knerr PJ, Van Der Donk WA, Ricklin D, Lambris JD. Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin Chemmedchem. 9: 2223-2226. DOI: 10.1002/cmdc.201402212 |
0.415 |
|
2013 |
Knerr PJ, Van Der Donk WA. Chemical synthesis of the lantibiotic lacticin 481 reveals the importance of lanthionine stereochemistry Journal of the American Chemical Society. 135: 7094-7097. PMID 23621626 DOI: 10.1021/ja4014024 |
0.642 |
|
2012 |
Knerr PJ, Oman TJ, Garcia De Gonzalo CV, Lupoli TJ, Walker S, Van Der Donk WA. Non-proteinogenic amino acids in lacticin 481 analogues result in more potent inhibition of peptidoglycan transglycosylation Acs Chemical Biology. 7: 1791-1795. PMID 22920239 DOI: 10.1021/Cb300372B |
0.729 |
|
2012 |
Knerr PJ, Van Der Donk WA. Chemical synthesis and biological activity of analogues of the lantibiotic epilancin 15X Journal of the American Chemical Society. 134: 7648-7651. PMID 22524291 DOI: 10.1021/ja302435y |
0.642 |
|
2012 |
Oman TJ, Knerr PJ, Bindman NA, Velásquez JE, Van Der Donk WA. An engineered lantibiotic synthetase that does not require a leader peptide on its substrate Journal of the American Chemical Society. 134: 6952-6955. PMID 22480178 DOI: 10.1021/ja3017297 |
0.563 |
|
2012 |
Knerr PJ, Van Der Donk WA. Discovery, biosynthesis, and engineering of lantipeptides Annual Review of Biochemistry. 81: 479-505. PMID 22404629 DOI: 10.1146/annurev-biochem-060110-113521 |
0.565 |
|
2011 |
Knerr PJ, Tzekou A, Ricklin D, Qu H, Chen H, Van Der Donk WA, Lambris JD. Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin Acs Chemical Biology. 6: 753-760. PMID 21520911 DOI: 10.1021/Cb2000378 |
0.713 |
|
2011 |
Micklitsch CM, Knerr PJ, Branco MC, Nagarkar R, Pochan DJ, Schneider JP. Zinc-triggered hydrogelation of a self-assembling β-hairpin peptide. Angewandte Chemie (International Ed. in English). 50: 1577-9. PMID 21308908 DOI: 10.1002/Anie.201006652 |
0.324 |
|
2010 |
Li B, Sher D, Kelly L, Shi Y, Huang K, Knerr PJ, Joewono I, Rusch D, Chisholm SW, van der Donk WA. Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 107: 10430-5. PMID 20479271 DOI: 10.1073/Pnas.0913677107 |
0.709 |
|
2009 |
Levengood MR, Knerr PJ, Oman TJ, Van Der Donk WA. In vitro mutasynthesis of lantibiotic analogues containing nonproteinogenic amino acids Journal of the American Chemical Society. 131: 12024-12025. PMID 19655738 DOI: 10.1021/ja903239s |
0.624 |
|
Low-probability matches (unlikely to be authored by this person) |
2012 |
Knerr PJ, Branco MC, Nagarkar R, Pochan DJ, Schneider JP. Heavy metal ion hydrogelation of a self-assembling peptide via cysteinyl chelation Journal of Materials Chemistry. 22: 1352-1357. DOI: 10.1039/C1Jm14418A |
0.289 |
|
2019 |
Knerr PJ, Mowery SA, Finan B, Perez-Tilve D, Tschöp MH, DiMarchi RD. Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates. Peptides. 170225. PMID 31786282 DOI: 10.1016/J.Peptides.2019.170225 |
0.275 |
|
2017 |
Knerr PJ, Finan B, Gelfanov V, Perez-Tilve D, Tschöp MH, DiMarchi RD. Optimization of peptide-based polyagonists for treatment of diabetes and obesity. Bioorganic & Medicinal Chemistry. PMID 29153547 DOI: 10.1016/J.Bmc.2017.10.047 |
0.27 |
|
2022 |
Yang B, Gelfanov VM, El K, Chen A, Rohlfs R, DuBois B, Kruse Hansen AM, Perez-Tilve D, Knerr PJ, D'Alessio D, Campbell JE, Douros JD, Finan B. Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems. Molecular Metabolism. 101638. PMID 36400403 DOI: 10.1016/j.molmet.2022.101638 |
0.252 |
|
2014 |
Huang Y, Reis ES, Knerr PJ, van der Donk WA, Ricklin D, Lambris JD. Cover Picture: Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin (ChemMedChem 10/2014) Chemmedchem. 9: 2209-2209. DOI: 10.1002/Cmdc.201490037 |
0.134 |
|
2023 |
Liskiewicz A, Khalil A, Liskiewicz D, Novikoff A, Grandl G, Maity-Kumar G, Gutgesell RM, Bakhti M, Bastidas-Ponce A, Czarnecki O, Makris K, Lickert H, Feuchtinger A, Tost M, Coupland C, ... ... Knerr PJ, et al. Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice. Nature Metabolism. PMID 37946085 DOI: 10.1038/s42255-023-00931-7 |
0.08 |
|
2022 |
Quarta C, Stemmer K, Novikoff A, Yang B, Klingelhuber F, Harger A, Bakhti M, Bastidas-Ponce A, Baugé E, Campbell JE, Capozzi M, Clemmensen C, Collden G, Cota P, Douros J, ... ... Knerr PJ, et al. GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice. Nature Metabolism. 4: 1071-1083. PMID 35995995 DOI: 10.1038/s42255-022-00617-6 |
0.075 |
|
2021 |
Zhang Q, Delessa CT, Augustin R, Bakhti M, Colldén G, Drucker DJ, Feuchtinger A, Caceres CG, Grandl G, Harger A, Herzig S, Hofmann S, Holleman CL, Jastroch M, Keipert S, ... ... Knerr PJ, et al. The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling. Cell Metabolism. PMID 33571454 DOI: 10.1016/j.cmet.2021.01.015 |
0.045 |
|
2021 |
Novikoff A, O'Brien SL, Bernecker M, Grandl G, Kleinert M, Knerr PJ, Stemmer K, Klingenspor M, Zeigerer A, DiMarchi R, Tschöp MH, Finan B, Calebiro D, Müller TD. Spatiotemporal GLP-1 and GIPR receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists. Molecular Metabolism. 101181. PMID 33556643 DOI: 10.1016/j.molmet.2021.101181 |
0.038 |
|
2013 |
Moesgen D, Klein M, Köhler T, Knerr P, Schröder H. Pharmacological neuroenhancement - Epidemiological and causal research | Pharmakologisches Neuroenhancement - Epidemiologie und Ursachenforschung Suchttherapie. 14: 8-15. DOI: 10.1055/s-0032-1333266 |
0.01 |
|
Hide low-probability matches. |