| Year |
Citation |
Score |
| 2014 |
Goldberg JM, Chen X, Meinhardt N, Greenbaum DC, Petersson EJ. Thioamide-based fluorescent protease sensors. Journal of the American Chemical Society. 136: 2086-93. PMID 24472041 DOI: 10.1021/Ja412297X |
0.334 |
|
| 2013 |
Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D, Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC. A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites. Cell Host & Microbe. 13: 15-28. PMID 23332153 DOI: 10.1016/J.Chom.2012.12.001 |
0.733 |
|
| 2012 |
Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, ... ... Greenbaum DC, et al. Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host & Microbe. 12: 815-23. PMID 23245326 DOI: 10.1016/J.Chom.2012.10.017 |
0.73 |
|
| 2012 |
Harbut MB, Patel BA, Yeung BK, McNamara CW, Bright AT, Ballard J, Supek F, Golde TE, Winzeler EA, Diagana TT, Greenbaum DC. Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design. Proceedings of the National Academy of Sciences of the United States of America. 109: 21486-91. PMID 23236186 DOI: 10.1073/Pnas.1216016110 |
0.792 |
|
| 2012 |
Jo H, Meinhardt N, Wu Y, Kulkarni S, Hu X, Low KE, Davies PL, DeGrado WF, Greenbaum DC. Development of α-helical calpain probes by mimicking a natural protein-protein interaction. Journal of the American Chemical Society. 134: 17704-13. PMID 22998171 DOI: 10.1021/Ja307599Z |
0.356 |
|
| 2012 |
Önder Ö, Humphrey PT, McOmber B, Korobova F, Francella N, Greenbaum DC, Brisson D. OspC is potent plasminogen receptor on surface of Borrelia burgdorferi. The Journal of Biological Chemistry. 287: 16860-8. PMID 22433849 DOI: 10.1074/Jbc.M111.290775 |
0.396 |
|
| 2012 |
Kalińska M, Kantyka T, Greenbaum DC, Larsen KS, Władyka B, Jabaiah A, Bogyo M, Daugherty PS, Wysocka M, Jaros M, Lesner A, Rolka K, Schaschke N, Stennicke H, Dubin A, et al. Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C. Biochimie. 94: 318-27. PMID 21802486 DOI: 10.1016/J.Biochi.2011.07.020 |
0.311 |
|
| 2011 |
Doyle PS, Zhou YM, Hsieh I, Greenbaum DC, McKerrow JH, Engel JC. The Trypanosoma cruzi protease cruzain mediates immune evasion. Plos Pathogens. 7: e1002139. PMID 21909255 DOI: 10.1371/Journal.Ppat.1002139 |
0.451 |
|
| 2011 |
Millholland MG, Chandramohanadas R, Pizzarro A, Wehr A, Shi H, Darling C, Lim CT, Greenbaum DC. The malaria parasite progressively dismantles the host erythrocyte cytoskeleton for efficient egress. Molecular & Cellular Proteomics : McP. 10: M111.010678. PMID 21903871 DOI: 10.1074/Mcp.M111.010678 |
0.725 |
|
| 2011 |
Harbut MB, Velmourougane G, Dalal S, Reiss G, Whisstock JC, Onder O, Brisson D, McGowan S, Klemba M, Greenbaum DC. Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases. Proceedings of the National Academy of Sciences of the United States of America. 108: E526-34. PMID 21844374 DOI: 10.1073/Pnas.1105601108 |
0.78 |
|
| 2011 |
Velmourougane G, Harbut MB, Dalal S, McGowan S, Oellig CA, Meinhardt N, Whisstock JC, Klemba M, Greenbaum DC. Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase. Journal of Medicinal Chemistry. 54: 1655-66. PMID 21366301 DOI: 10.1021/Jm101227T |
0.722 |
|
| 2010 |
Lucumi E, Darling C, Jo H, Napper AD, Chandramohanadas R, Fisher N, Shone AE, Jing H, Ward SA, Biagini GA, DeGrado WF, Diamond SL, Greenbaum DC. Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrobial Agents and Chemotherapy. 54: 3597-604. PMID 20547797 DOI: 10.1128/Aac.00431-10 |
0.479 |
|
| 2010 |
Shah PP, Wang T, Kaletsky RL, Myers MC, Purvis JE, Jing H, Huryn DM, Greenbaum DC, Smith AB, Bates P, Diamond SL. A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. Molecular Pharmacology. 78: 319-24. PMID 20466822 DOI: 10.1124/Mol.110.064261 |
0.353 |
|
| 2009 |
Greenbaum DC, FitzGerald GA. Platelets, pyrexia, and plasmodia. The New England Journal of Medicine. 361: 526-8. PMID 19641212 DOI: 10.1056/Nejmcibr0903050 |
0.357 |
|
| 2009 |
Golde TE, Wolfe MS, Greenbaum DC. Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins. Seminars in Cell & Developmental Biology. 20: 225-30. PMID 19429495 DOI: 10.1016/J.Semcdb.2009.02.003 |
0.336 |
|
| 2009 |
Chandramohanadas R, Davis PH, Beiting DP, Harbut MB, Darling C, Velmourougane G, Lee MY, Greer PA, Roos DS, Greenbaum DC. Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science (New York, N.Y.). 324: 794-7. PMID 19342550 DOI: 10.1126/Science.1171085 |
0.797 |
|
| 2008 |
Harbut MB, Velmourougane G, Reiss G, Chandramohanadas R, Greenbaum DC. Development of bestatin-based activity-based probes for metallo-aminopeptidases. Bioorganic & Medicinal Chemistry Letters. 18: 5932-6. PMID 18823778 DOI: 10.1016/J.Bmcl.2008.09.021 |
0.706 |
|
| 2008 |
Greenbaum DC. Is chemical genetics the new frontier for malaria biology? Trends in Pharmacological Sciences. 29: 51-6. PMID 18199489 DOI: 10.1016/J.Tips.2007.11.008 |
0.363 |
|
| 2008 |
Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. Journal of Medicinal Chemistry. 51: 545-52. PMID 18173229 DOI: 10.1021/Jm070760L |
0.742 |
|
| 2007 |
Cuerrier D, Moldoveanu T, Campbell RL, Kelly J, Yoruk B, Verhelst SH, Greenbaum D, Bogyo M, Davies PL. Development of calpain-specific inactivators by screening of positional scanning epoxide libraries. The Journal of Biological Chemistry. 282: 9600-11. PMID 17218315 DOI: 10.1074/Jbc.M610372200 |
0.344 |
|
| 2006 |
Choe Y, Leonetti F, Greenbaum DC, Lecaille F, Bogyo M, Brömme D, Ellman JA, Craik CS. Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities. The Journal of Biological Chemistry. 281: 12824-32. PMID 16520377 DOI: 10.1074/Jbc.M513331200 |
0.355 |
|
| 2005 |
Sanders PR, Gilson PR, Cantin GT, Greenbaum DC, Nebl T, Carucci DJ, McConville MJ, Schofield L, Hodder AN, Yates JR, Crabb BS. Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum. The Journal of Biological Chemistry. 280: 40169-76. PMID 16203726 DOI: 10.1074/Jbc.M509631200 |
0.411 |
|
| 2004 |
Bogyo M, Baruch A, Jeffery DA, Greenbaum D, Borodovsky A, Ovaa H, Kessler B. Applications for chemical probes of proteolytic activity. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 21.17. PMID 18429259 DOI: 10.1002/0471140864.Ps2117S36 |
0.363 |
|
| 2004 |
Mackey ZB, O'Brien TC, Greenbaum DC, Blank RB, McKerrow JH. A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei. The Journal of Biological Chemistry. 279: 48426-33. PMID 15326171 DOI: 10.1074/Jbc.M402470200 |
0.473 |
|
| 2004 |
Oleksy A, Golonka E, Bańbuła A, Szmyd G, Moon J, Kubica M, Greenbaum D, Bogyo M, Foster TJ, Travis J, Potempa J. Growth phase-dependent production of a cell wall-associated elastinolytic cysteine proteinase by Staphylococcus epidermidis. Biological Chemistry. 385: 525-35. PMID 15255185 DOI: 10.1515/Bc.2004.062 |
0.365 |
|
| 2004 |
Eksi S, Czesny B, Greenbaum DC, Bogyo M, Williamson KC. Targeted disruption of Plasmodium falciparum cysteine protease, falcipain 1, reduces oocyst production, not erythrocytic stage growth. Molecular Microbiology. 53: 243-50. PMID 15225318 DOI: 10.1111/J.1365-2958.2004.04108.X |
0.418 |
|
| 2004 |
Greenbaum DC, Mackey Z, Hansell E, Doyle P, Gut J, Caffrey CR, Lehrman J, Rosenthal PJ, McKerrow JH, Chibale K. Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi. Journal of Medicinal Chemistry. 47: 3212-9. PMID 15163200 DOI: 10.1021/Jm030549J |
0.506 |
|
| 2004 |
Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, Tsai FY, Greenbaum DC, Hager JH, Bogyo M, Hanahan D. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell. 5: 443-53. PMID 15144952 DOI: 10.1016/S1535-6108(04)00111-4 |
0.302 |
|
| 2004 |
Medzihradszky KF, Darula Z, Perlson E, Fainzilber M, Chalkley RJ, Ball H, Greenbaum D, Bogyo M, Tyson DR, Bradshaw RA, Burlingame AL. O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes. Molecular & Cellular Proteomics : McP. 3: 429-40. PMID 14752058 DOI: 10.1074/Mcp.M300140-Mcp200 |
0.423 |
|
| 2003 |
Sajid M, McKerrow JH, Hansell E, Mathieu MA, Lucas KD, Hsieh I, Greenbaum D, Bogyo M, Salter JP, Lim KC, Franklin C, Kim JH, Caffrey CR. Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase. Molecular and Biochemical Parasitology. 131: 65-75. PMID 12967713 DOI: 10.1016/S0166-6851(03)00194-4 |
0.415 |
|
| 2003 |
Yasothornsrikul S, Greenbaum D, Medzihradszky KF, Toneff T, Bundey R, Miller R, Schilling B, Petermann I, Dehnert J, Logvinova A, Goldsmith P, Neveu JM, Lane WS, Gibson B, Reinheckel T, et al. Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter. Proceedings of the National Academy of Sciences of the United States of America. 100: 9590-5. PMID 12869695 DOI: 10.1073/Pnas.1531542100 |
0.3 |
|
| 2002 |
Greenbaum DC, Baruch A, Grainger M, Bozdech Z, Medzihradszky KF, Engel J, DeRisi J, Holder AA, Bogyo M. A role for the protease falcipain 1 in host cell invasion by the human malaria parasite. Science (New York, N.Y.). 298: 2002-6. PMID 12471262 DOI: 10.1126/Science.1077426 |
0.591 |
|
| 2002 |
Greenbaum DC, Arnold WD, Lu F, Hayrapetian L, Baruch A, Krumrine J, Toba S, Chehade K, Brömme D, Kuntz ID, Bogyo M. Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design. Chemistry & Biology. 9: 1085-94. PMID 12401493 DOI: 10.1016/S1074-5521(02)00238-7 |
0.331 |
|
| 2002 |
Greenbaum D, Baruch A, Hayrapetian L, Darula Z, Burlingame A, Medzihradszky KF, Bogyo M. Chemical approaches for functionally probing the proteome. Molecular & Cellular Proteomics : McP. 1: 60-8. PMID 12096141 DOI: 10.1074/Mcp.T100003-Mcp200 |
0.34 |
|
| 2000 |
Bogyo M, Verhelst S, Bellingard-Dubouchaud V, Toba S, Greenbaum D. Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs Chemistry and Biology. 7: 27-38. PMID 10662686 DOI: 10.1016/S1074-5521(00)00061-2 |
0.31 |
|
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