Marcia Gordon - Publications

Affiliations: 
University of South Florida, Tampa, FL, United States 
Area:
Neuroscience Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tetlow AM, Jackman BM, Alhadidy MM, Muskus P, Morgan DG, Gordon MN. Neural atrophy produced by AAV tau injections into hippocampus and anterior cortex of middle-aged mice. Neurobiology of Aging. 124: 39-50. PMID 36739619 DOI: 10.1016/j.neurobiolaging.2022.06.014  0.396
2022 Finneran D, Li Q, Subbarayan MS, Joly-Amado A, Kamath S, Dengler DG, Gordon MN, Jackson MR, Morgan D, Bickford PC, Smith LH, Nash KR. Concentration and proteolysis of CX3CL1 may regulate the microglial response to CX3CL1. Glia. PMID 36106533 DOI: 10.1002/glia.24269  0.559
2022 Wang Y, Hong Y, Yan J, Brown B, Lin X, Zhang X, Shen N, Li M, Cai J, Gordon M, Morgan D, Zhou Q, Cao C. Low-Dose Delta-9-Tetrahydrocannabinol as Beneficial Treatment for Aged APP/PS1 Mice. International Journal of Molecular Sciences. 23. PMID 35269905 DOI: 10.3390/ijms23052757  0.39
2021 Loon A, Zamudio F, Sanneh A, Brown B, Smeltzer S, Brownlow ML, Quadri Z, Peters M, Weeber E, Nash K, Lee DC, Gordon MN, Morgan D, Selenica MB. Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged mice. Geroscience. PMID 34410588 DOI: 10.1007/s11357-021-00408-z  0.814
2021 Boche D, Gordon MN. Diversity of transcriptomic microglial phenotypes in aging and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34223696 DOI: 10.1002/alz.12389  0.319
2021 Ma C, Hunt JB, Kovalenko A, Liang H, Selenica MB, Orr MB, Zhang B, Gensel JC, Feola DJ, Gordon MN, Morgan D, Bickford PC, Lee DC. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. Frontiers in Immunology. 12: 628156. PMID 34046031 DOI: 10.3389/fimmu.2021.628156  0.814
2020 Ma C, Hunt JB, Selenica MB, Sanneh A, Sandusky-Beltran LA, Watler M, Daas R, Kovalenko A, Liang H, Placides D, Cao C, Lin X, Orr MB, Zhang B, Gensel JC, ... ... Gordon MN, et al. Arginase 1 Insufficiency Precipitates Amyloid- Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Frontiers in Immunology. 11: 582998. PMID 33519806 DOI: 10.3389/fimmu.2020.582998  0.837
2020 Joly-Amado A, Hunter J, Quadri Z, Zamudio F, Rocha-Rangel PV, Chan D, Kesarwani A, Nash K, Lee DC, Morgan D, Gordon MN, Selenica MB. CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy. Frontiers in Immunology. 11: 997. PMID 32508844 DOI: 10.3389/fimmu.2020.00997  0.816
2019 Joly-Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, Zagorski K, Antonyan T, Hovakimyan A, Paek HJ, Gordon MN, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A, et al. Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology. Neurobiology of Disease. 104636. PMID 31629891 DOI: 10.1016/J.Nbd.2019.104636  0.661
2019 Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, ... ... Gordon MN, et al. Spermidine/spermine-N-acetyltransferase ablation impacts tauopathy-induced polyamine stress response. Alzheimer's Research & Therapy. 11: 58. PMID 31253191 DOI: 10.1186/S13195-019-0507-Y  0.8
2019 Tetlow AM, Joly-Amado A, Gordon MN, Morgan D. P4-158: CHANGES ACROSS THE LIFESPAN IN TG4510 MICE Alzheimer's & Dementia. 15: P1335-P1335. DOI: 10.1016/j.jalz.2019.06.3820  0.593
2019 Alhadidy MM, Soliman AS, Tetlow AM, Kara B, Kozikowski A, Gordon MN, Morgan D. P4-039: A Novel Histone Deacetylase 6 (Hdac6) Inhibitor To Mitigate Tau Pathology In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3698  0.571
2019 Gordon MN, Beck JS, Kanaan NM, Winn ME, Ginsberg SD, Counts SE. P3-173: MICROARRAY ANALYSES REVEAL SENESCENCE-ASSOCIATED GENE EXPRESSION IN ALZHEIMER'S DISEASE AND TRANSGENIC MOUSE MODELS WITH AMYLOID DEPOSITION OR TAUOPATHY Alzheimer's & Dementia. 15: P996-P997. DOI: 10.1016/J.Jalz.2019.06.3202  0.387
2018 Finneran DJ, Morgan D, Gordon MN, Nash KR. CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 30499006 DOI: 10.1007/s11481-018-9822-5  0.636
2017 Schroeder S, Joly-Amado A, Soliman A, Sengupta U, Kayed R, Gordon MN, Morgan D. Oligomeric tau-targeted immunotherapy in Tg4510 mice. Alzheimer's Research & Therapy. 9: 46. PMID 28655349 DOI: 10.1186/s13195-017-0274-6  0.4
2017 Stevanovic K, Yunus A, Joly-Amado A, Gordon M, Morgan D, Gulick D, Gamsby J. Disruption of normal circadian clock function in a mouse model of tauopathy. Experimental Neurology. PMID 28461004 DOI: 10.1016/J.Expneurol.2017.04.015  0.406
2016 Joly-Amado A, Serraneau KS, Brownlow M, Marín de Evsikova C, Speakman JR, Gordon MN, Morgan D. Metabolic changes over the course of aging in a mouse model of tau deposition. Neurobiology of Aging. 44: 62-73. PMID 27318134 DOI: 10.1016/J.Neurobiolaging.2016.04.013  0.646
2016 Selenica MB, Reid P, Pena G, Alvarez J, Hunt JB, Nash KR, Morgan D, Gordon MN, Lee DC. Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. Journal of Immunological Methods. PMID 26784524 DOI: 10.1016/J.Jim.2016.01.008  0.77
2015 Hunt JB, Nash KR, Placides D, Moran P, Selenica ML, Abuqalbeen F, Ratnasamy K, Slouha N, Rodriguez-Ospina S, Savlia M, Ranaweera Y, Reid P, Dickey CA, Uricia R, Yang CG, ... ... Gordon MN, et al. Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14842-60. PMID 26538654 DOI: 10.1523/Jneurosci.3959-14.2015  0.681
2015 Schroeder SK, Joly-Amado A, Gordon MN, Morgan D. Tau-Directed Immunotherapy: A Promising Strategy for Treating Alzheimer's Disease and Other Tauopathies. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26538351 DOI: 10.1007/S11481-015-9637-6  0.639
2015 Cheng J, Lin X, Morgan D, Gordon M, Chen X, Wang ZH, Li HN, He LJ, Zhou SF, Cao C. Dendritic and langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy. Oncotarget. PMID 26473448 DOI: 10.18632/Oncotarget.6123  0.42
2015 Sanneh A, Johnson N, Housley SB, Manchec B, Liu J, Nash K, Lee DC, Gordon MN, Morgan D, Selenica MB. Characterization of full length and c-terminal truncated tau pathological progression with age in wild type mice Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.873  0.63
2014 Selenica ML, Davtyan H, Housley SB, Blair LJ, Gillies A, Nordhues BA, Zhang B, Liu J, Gestwicki JE, Lee DC, Gordon MN, Morgan D, Dickey CA. Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis. Journal of Neuroinflammation. 11: 152. PMID 25183004 DOI: 10.1186/S12974-014-0152-0  0.652
2014 Joly-Amado A, Brownlow M, Pierce J, Ravipati A, Showalter E, Li Q, Gordon MN, Morgan D. Intraventricular human immunoglobulin distributes extensively but fails to modify amyloid in a mouse model of amyloid deposition. Current Alzheimer Research. 11: 664-71. PMID 25115543 DOI: 10.2174/1567205011666140812114341  0.699
2014 Quiroga C, Chaparro RE, Karlnoski R, Erasso D, Gordon M, Morgan D, Bosco G, Rubini A, Parmagnani A, Paoli A, Mangar D, Camporesi EM. Effects of repetitive exposure to anesthetics and analgesics in the Tg2576 mouse Alzheimer's model. Neurotoxicity Research. 26: 414-21. PMID 24927827 DOI: 10.1007/S12640-014-9478-8  0.54
2014 Brownlow ML, Joly-Amado A, Azam S, Elza M, Selenica ML, Pappas C, Small B, Engelman R, Gordon MN, Morgan D. Partial rescue of memory deficits induced by calorie restriction in a mouse model of tau deposition. Behavioural Brain Research. 271: 79-88. PMID 24925454 DOI: 10.1016/J.Bbr.2014.06.001  0.667
2014 Selenica ML, Benner L, Housley SB, Manchec B, Lee DC, Nash KR, Kalin J, Bergman JA, Kozikowski A, Gordon MN, Morgan D. Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition. Alzheimer's Research & Therapy. 6: 12. PMID 24576665 DOI: 10.1186/Alzrt241  0.588
2013 Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology. Plos One. 8: e75713. PMID 24069439 DOI: 10.1371/Journal.Pone.0075713  0.66
2013 Selenica ML, Alvarez JA, Nash KR, Lee DC, Cao C, Lin X, Reid P, Mouton PR, Morgan D, Gordon MN. Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain. Journal of Neuroinflammation. 10: 86. PMID 23866683 DOI: 10.1186/1742-2094-10-86  0.498
2013 Carty N, Nash KR, Brownlow M, Cruite D, Wilcock D, Selenica ML, Lee DC, Gordon MN, Morgan D. Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice. Plos One. 8: e59626. PMID 23555730 DOI: 10.1371/Journal.Pone.0059626  0.656
2013 Lee DC, Ruiz CR, Lebson L, Selenica ML, Rizer J, Hunt JB, Rojiani R, Reid P, Kammath S, Nash K, Dickey CA, Gordon M, Morgan D. Aging enhances classical activation but mitigates alternative activation in the central nervous system. Neurobiology of Aging. 34: 1610-20. PMID 23481567 DOI: 10.1016/J.Neurobiolaging.2012.12.014  0.77
2013 Nash KR, Lee DC, Hunt JB, Morganti JM, Selenica ML, Moran P, Reid P, Brownlow M, Guang-Yu Yang C, Savalia M, Gemma C, Bickford PC, Gordon MN, Morgan D. Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy. Neurobiology of Aging. 34: 1540-8. PMID 23332170 DOI: 10.1016/J.Neurobiolaging.2012.12.011  0.832
2013 Lee DC, Rizer J, Hunt JB, Selenica ML, Gordon MN, Morgan D. Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology. Neuropathology and Applied Neurobiology. 39: 69-85. PMID 23171029 DOI: 10.1111/Nan.12002  0.701
2013 Selenica ML, Brownlow M, Jimenez JP, Lee DC, Pena G, Dickey CA, Gordon MN, Morgan D. Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy. Neuro-Degenerative Diseases. 11: 165-81. PMID 22796753 DOI: 10.1159/000337230  0.632
2013 Nakamura M, Kaneko S, Ito H, Jiang S, Fujita K, Wate R, Nakano S, Fujisawa J, Kusaka H, Flunkert S, Hierzer M, Löffler T, Rabl R, Neddens J, Duller S, ... ... Gordon MN, et al. Contents Vol. 11, 2013 Neurodegenerative Diseases. 11. DOI: 10.1159/000350668  0.443
2013 Hunt J, Nash K, Placides D, Moran P, Rodrigez‐Ospina S, Yang CG, Savlia M, Selenica M, Gordon MN, Morgan D, Lee D. P1–410: Arginase‐1 overexpression reduces tau pathology in rTg4510 tau transgenic mice Alzheimer's & Dementia. 9. DOI: 10.1016/j.jalz.2013.05.638  0.435
2012 Li Q, Lebson L, Lee DC, Nash K, Grimm J, Rosenthal A, Selenica ML, Morgan D, Gordon MN. Chronological age impacts immunotherapy and monocyte uptake independent of amyloid load. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 202-14. PMID 22198698 DOI: 10.1007/S11481-011-9329-9  0.823
2012 Nash K, Lee D, Morganti J, Gemma L, Bickford P, Gordon MN, Morgan D. Fractalkine signalling decreases tau pathology in tau depositing mice Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.032  0.815
2011 Wilcock DM, Zhao Q, Morgan D, Gordon MN, Everhart A, Wilson JG, Lee JE, Colton CA. Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses. Asn Neuro. 3: 249-58. PMID 21995345 DOI: 10.1042/An20110018  0.697
2011 Wilcock DM, Morgan D, Gordon MN, Taylor TL, Ridnour LA, Wink DA, Colton CA. Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence. Journal of Neuroinflammation. 8: 115. PMID 21906275 DOI: 10.1186/1742-2094-8-115  0.605
2010 Carty N, Lee D, Dickey C, Ceballos-Diaz C, Jansen-West K, Golde TE, Gordon MN, Morgan D, Nash K. Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain. Journal of Neuroscience Methods. 194: 144-53. PMID 20951738 DOI: 10.1016/J.Jneumeth.2010.10.010  0.532
2010 Lee DC, Rizer J, Selenica ML, Reid P, Kraft C, Johnson A, Blair L, Gordon MN, Dickey CA, Morgan D. LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice. Journal of Neuroinflammation. 7: 56. PMID 20846376 DOI: 10.1186/1742-2094-7-56  0.697
2010 Lebson L, Nash K, Kamath S, Herber D, Carty N, Lee DC, Li Q, Szekeres K, Jinwal U, Koren J, Dickey CA, Gottschall PE, Morgan D, Gordon MN. Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9651-8. PMID 20660248 DOI: 10.1523/Jneurosci.0329-10.2010  0.818
2010 Ajmo JM, Bailey LA, Howell MD, Cortez LK, Pennypacker KR, Mehta HN, Morgan D, Gordon MN, Gottschall PE. Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw. Journal of Neurochemistry. 113: 784-95. PMID 20180882 DOI: 10.1111/J.1471-4159.2010.06647.X  0.719
2010 Li QY, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. Virus-like peptide vaccines against Abeta N-terminal or C-terminal domains reduce amyloid deposition in APP transgenic mice without addition of adjuvant. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 133-42. PMID 20066498 DOI: 10.1007/S11481-009-9183-1  0.624
2010 Williams EC, Toomey R, Gordon M, Williams D, Morgan D, Alcantar N. Abstract 3707: Design and characterization of a double packaged system for localized drug delivery for the treatment of cancers Cancer Research. 70: 3707-3707. DOI: 10.1158/1538-7445.Am10-3707  0.557
2010 Lee DC, Malthankar-Phatak G, Reid P, Alvarez J, Gordon MN, Siman R, Morgan D. P1-311: Differential response for amyloid clearance in APP Tg2576 mice and APP/PS1 double knockin mice following intracranial LPS Alzheimer's & Dementia. 6: S263-S263. DOI: 10.1016/J.Jalz.2010.05.864  0.671
2010 Selenica MB, Nash K, Lee DC, Morgan D, Gordon MN. Brain infiltration of peripheral monocytes via AAV-9 driven chemokine overexpression Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1820  0.527
2010 Nash KR, Brownlow M, Carty N, Cruite D, Selenica M, Gordon M, Morgan D. P3-305: Long-term reduction of Aβ deposits in APP + PS1 transgenic mice via adeno-associated viral vector mediated gene delivery of neprilysin Alzheimer's & Dementia. 6: S541-S541. DOI: 10.1016/J.Jalz.2010.05.1806  0.686
2009 Karlnoski RA, Rosenthal A, Kobayashi D, Pons J, Alamed J, Mercer M, Li Q, Gordon MN, Gottschall PE, Morgan D. Suppression of amyloid deposition leads to long-term reductions in Alzheimer's pathologies in Tg2576 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4964-71. PMID 19369565 DOI: 10.1523/Jneurosci.4560-08.2009  0.497
2009 Lord A, Englund H, Söderberg L, Tucker S, Clausen F, Hillered L, Gordon M, Morgan D, Lannfelt L, Pettersson FE, Nilsson LN. Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice. The Febs Journal. 276: 995-1006. PMID 19215301 DOI: 10.1111/J.1742-4658.2008.06836.X  0.735
2008 Li Q, Gordon M, Etienne MA, Hammer RP, Morgan D. Contrasting In Vivo Effects of Two Peptide-Based Amyloid-β Protein Aggregation Inhibitors in a Transgenic Mouse Model of Amyloid Deposition. Cell Transplantation. 17: 397-408. PMID 28863742 DOI: 10.3727/096368908784423247  0.685
2008 Carty NC, Nash K, Lee D, Mercer M, Gottschall PE, Meyers C, Muzyczka N, Gordon MN, Morgan D. Adeno-associated Viral (AAV) Serotype 5 Vector Mediated Gene Delivery of Endothelin-converting Enzyme Reduces Aβ Deposits in APP + PS1 Transgenic Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1580-1586. PMID 28189012 DOI: 10.1038/Mt.2008.148  0.698
2008 Morgan D, Munireddy S, Alamed J, DeLeon J, Diamond DM, Bickford P, Hutton M, Lewis J, McGowan E, Gordon MN. Apparent behavioral benefits of tau overexpression in P301L tau transgenic mice. Journal of Alzheimer's Disease : Jad. 15: 605-14. PMID 19096159 DOI: 10.3233/Jad-2008-15407  0.684
2008 Carty NC, Nash K, Lee D, Mercer M, Gottschall PE, Meyers C, Muzyczka N, Gordon MN, Morgan D. Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Abeta deposits in APP + PS1 transgenic mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1580-6. PMID 18665160 DOI: 10.1038/mt.2008.148  0.701
2008 Karlnoski RA, Rosenthal A, Alamed J, Ronan V, Gordon MN, Gottschall PE, Grimm J, Pons J, Morgan D. Deglycosylated anti-Abeta antibody dose-response effects on pathology and memory in APP transgenic mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 3: 187-97. PMID 18607758 DOI: 10.1007/S11481-008-9114-6  0.672
2008 Li Q, Gordon M, Etienne MA, Hammer RP, Morgan D. Contrasting in vivo effects of two peptide-based amyloid-beta protein aggregation inhibitors in a transgenic mouse model of amyloid deposition. Cell Transplantation. 17: 397-408. PMID 18522242 DOI: 10.3727/096368908784423247  0.707
2008 Morgan D, Gordon MN. Amyloid, hyperactivity, and metabolism: theoretical comment on Vloeberghs et al. (2008). Behavioral Neuroscience. 122: 730-2. PMID 18513144 DOI: 10.1037/0735-7044.122.3.730  0.663
2008 Golub MS, Germann SL, Mercer M, Gordon MN, Morgan DG, Mayer LP, Hoyer PB. Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse. Neurobiology of Aging. 29: 1512-23. PMID 17451844 DOI: 10.1016/J.Neurobiolaging.2007.03.015  0.366
2008 Lord A, Englund H, Clausen F, Hillered L, Pettersson FE, Gordon M, Morgan D, Lannfelt L, Nilsson LN. O3-01-01: Amyloid-β protofibrils are linked to cognitive impairment in Alzheimer's disease transgenic mice Alzheimer's & Dementia. 4: T157-T157. DOI: 10.1016/J.Jalz.2008.05.405  0.677
2008 Lee DC, Gordon M, Morgan D. P3-365: Polarization of microglia modifies amyloid pathology in APP Tg2576 mice Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1935  0.701
2008 Lebson LA, Morgan D, Gordon MN. P3-363: Time course of monocyte infiltration into brain and organs in amyloid-depositing APP+PS1 and nontransgenic mice Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1933  0.82
2008 Carty NC, Meyers C, Nash K, Muzyckza N, Gordon MN, Morgan D. P2-425: Systemic mannitol administration with convection enhanced delivery of rAAV increases area of gene distribution and uptake in mouse hippocampus Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1504  0.513
2008 Li Q, Gordon MN, Chackerian B, Alamed J, Ugen KE, Morgan D. P2-342: Vaccination of amyloid precursor protein transgenic mice with a bacteriophage-based short amyloid-β peptide vaccines without adjuvant induce a strong Th2-type anti-amyloid-β IgG and IgM response and reduce amyloid-β burden Alzheimer's & Dementia. 4: T473-T473. DOI: 10.1016/J.Jalz.2008.05.1419  0.623
2007 Herber DL, Mercer M, Roth LM, Symmonds K, Maloney J, Wilson N, Freeman MJ, Morgan D, Gordon MN. Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 222-31. PMID 18040847 DOI: 10.1007/S11481-007-9069-Z  0.648
2007 Li Q, Gordon M, Cao C, Ugen KE, Morgan D. Improvement of a low pH antigen-antibody dissociation procedure for ELISA measurement of circulating anti-Abeta antibodies. Bmc Neuroscience. 8: 22. PMID 17374155 DOI: 10.1186/1471-2202-8-22  0.655
2007 Wilcock DM, Jantzen PT, Li Q, Morgan D, Gordon MN. Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid. Neuroscience. 144: 950-60. PMID 17137722 DOI: 10.1016/J.Neuroscience.2006.10.020  0.654
2007 Karlnoski R, Wilcock D, Dickey C, Ronan V, Gordon MN, Zhang W, Morgan D, Taglialatela G. Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection Neurobiology of Disease. 25: 179-188. PMID 17067805 DOI: 10.1016/J.Nbd.2006.09.007  0.695
2007 Rojiani AM, Ambegaoankar M, Gordon MN, Breitner JCS, Morgan D. The H-2 receptor antagonist cimetidine blocks kainic acid toxicity in hippocampus as effectively as the NMDA receptor antagonist MK-801: 40.8 Journal of Neuropathology and Experimental Neurology. 66: 420. DOI: 10.1097/01.Jnen.0000268982.06535.5E  0.471
2007 Rojiani AM, Ambegaoankar M, Gordon MN, Breitner JCS, Morgan D. The H-2 Receptor Antagonist Cimetidine Blocks Kainic Acid Toxicity in Hippocampus as Effectively as the NMDA Receptor Antagonist MK-801 The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A20-B  0.471
2006 Alamed J, Wilcock DM, Diamond DM, Gordon MN, Morgan D. Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice. Nature Protocols. 1: 1671-9. PMID 17487150 DOI: 10.1038/Nprot.2006.275  0.571
2006 Wilcock DM, Gordon MN, Morgan D. Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain. Nature Protocols. 1: 1591-5. PMID 17406451 DOI: 10.1038/Nprot.2006.277  0.657
2006 Wilcock DM, Alamed J, Gottschall PE, Grimm J, Rosenthal A, Pons J, Ronan V, Symmonds K, Gordon MN, Morgan D. Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5340-6. PMID 16707786 DOI: 10.1523/Jneurosci.0695-06.2006  0.689
2006 Carty NC, Wilcock DM, Rosenthal A, Grimm J, Pons J, Ronan V, Gottschall PE, Gordon MN, Morgan D. Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice. Journal of Neuroinflammation. 3: 11. PMID 16686956 DOI: 10.1186/1742-2094-3-11  0.661
2006 Herber DL, Maloney JL, Roth LM, Freeman MJ, Morgan D, Gordon MN. Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia. 53: 382-91. PMID 16288481 DOI: 10.1002/Glia.20272  0.559
2006 Ewers M, Morgan DG, Gordon MN, Woodruff-Pak DS. Associative and motor learning in 12-month-old transgenic APP+PS1 mice. Neurobiology of Aging. 27: 1118-28. PMID 15993985 DOI: 10.1016/j.neurobiolaging.2005.05.019  0.451
2006 Tetlow AM, Joly-Amado A, Gordon MN, Morgan D. P3‐176: AGE AS A PREDICTOR OF DIFFERENT PHYSIOLOGICAL FORMS OF TAU Alzheimer's & Dementia. 14. DOI: 10.1016/j.jalz.2018.06.1534  0.564
2006 Lutz L, Mercer M, Freeman M, Ronan V, Wilcock D, Herber D, Gordon M, Morgan D. Phenotyping the microglial response using different activators in mouse CNS Experimental Neurology. 198: 579. DOI: 10.1016/J.Expneurol.2006.02.067  0.588
2006 Li Q, Gordon M, Tan J, Morgan D. Oral administration of green tea epigallocatechin-3-gallate (EGCG) reduces amyloid beta deposition in transgenic mouse model of Alzheimer's disease Experimental Neurology. 198: 576. DOI: 10.1016/J.Expneurol.2006.02.062  0.687
2006 Karlnoski R, Ronan V, Gordon M, Gottschall P, Rosenthal A, Grimm J, Morgan D. Low doses of deglycosylated anti-Aβ antibodies reduce amyloid pathology and reverse cognitive deficits in old app transgenic mice Experimental Neurology. 198: 573. DOI: 10.1016/J.Expneurol.2006.02.053  0.671
2006 Carty N, Ronan V, Meyers C, Nash K, Muzyckza N, Gordon M, Morgan D. AAV vector mediated gene delivery of endothelin converting enzyme-1 reduces β-amyloid deposits in transgenic APP + PS1 mice Experimental Neurology. 198: 562. DOI: 10.1016/J.Expneurol.2006.02.027  0.687
2005 Morgan D, Gordon MN, Tan J, Wilcock D, Rojiani AM. Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics. Journal of Neuropathology and Experimental Neurology. 64: 743-53. PMID 16141783 DOI: 10.1097/01.Jnen.0000178444.33972.E0  0.696
2005 Patel NV, Gordon MN, Connor KE, Good RA, Engelman RW, Mason J, Morgan DG, Morgan TE, Finch CE. Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiology of Aging. 26: 995-1000. PMID 15748777 DOI: 10.1016/j.neurobiolaging.2004.09.014  0.399
2005 Dickey CA, Gordon MN, Wilcock DM, Herber DL, Freeman MJ, Morgan D. Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice. Bmc Neuroscience. 6: 7. PMID 15689237 DOI: 10.1186/1471-2202-6-7  0.647
2004 Wilcock DM, Rojiani A, Rosenthal A, Subbarao S, Freeman MJ, Gordon MN, Morgan D. Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage. Journal of Neuroinflammation. 1: 24. PMID 15588287 DOI: 10.1186/1742-2094-1-24  0.73
2004 Herber DL, Roth LM, Wilson D, Wilson N, Mason JE, Morgan D, Gordon MN. Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice. Experimental Neurology. 190: 245-53. PMID 15473997 DOI: 10.1016/J.Expneurol.2004.07.007  0.642
2004 Herber DL, Severance EG, Cuevas J, Morgan D, Gordon MN. Biochemical and histochemical evidence of nonspecific binding of α7nAChR antibodies to mouse brain tissue Journal of Histochemistry and Cytochemistry. 52: 1367-1375. PMID 15385583 DOI: 10.1177/002215540405201013  0.569
2004 Wilcock DM, Rojiani A, Rosenthal A, Levkowitz G, Subbarao S, Alamed J, Wilson D, Wilson N, Freeman MJ, Gordon MN, Morgan D. Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6144-51. PMID 15240806 DOI: 10.1523/Jneurosci.1090-04.2004  0.694
2004 Li Q, Cao C, Chackerian B, Schiller J, Gordon M, Ugen KE, Morgan D. Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice. Bmc Neuroscience. 5: 21. PMID 15186505 DOI: 10.1186/1471-2202-5-21  0.692
2004 Garcia MF, Gordon MN, Hutton M, Lewis J, McGowan E, Dickey CA, Morgan D, Arendash GW. The retinal degeneration (rd) gene seriously impairs spatial cognitive performance in normal and Alzheimer's transgenic mice. Neuroreport. 15: 73-7. PMID 15106834 DOI: 10.1097/00001756-200401190-00015  0.607
2004 Wilcock DM, Munireddy SK, Rosenthal A, Ugen KE, Gordon MN, Morgan D. Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration. Neurobiology of Disease. 15: 11-20. PMID 14751766 DOI: 10.1016/J.Nbd.2003.09.015  0.66
2004 Dickey CA, Gordon MN, Mason JE, Wilson NJ, Diamond DM, Guzowski JF, Morgan D. Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice. Journal of Neurochemistry. 88: 434-42. PMID 14690531 DOI: 10.1111/J.1471-4159.2004.02185.X  0.712
2004 Wilcock DM, Rojiani A, Rosenthal A, Alamed J, Wilson D, Wilson N, Freeman MJ, Gordon MN, Morgan D. P4-366 Passive immunization with anti-Aβ antibodies reduces amyloid burden while producing a brief activation of microglia in a transgenic mouse model of amyloid deposition Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81924-9  0.675
2004 Herber DL, Roth LM, Freeman MJ, Morgan D, Gordon MN. P4-227 Lipopolysaccharide as a neuroinflammatory agent: evaluation of the time course of inflammatory markers using quantitative real time PCR, behavioral outcomes, and immunohistochemistry Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81785-8  0.481
2003 Dickey CA, Loring JF, Montgomery J, Gordon MN, Eastman PS, Morgan D. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5219-26. PMID 12832546 DOI: 10.1523/Jneurosci.23-12-05219.2003  0.673
2003 Austin L, Arendash GW, Gordon MN, Diamond DM, DiCarlo G, Dickey C, Ugen K, Morgan D. Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP + PS1 mice. Behavioral Neuroscience. 117: 478-84. PMID 12802876 DOI: 10.1037/0735-7044.117.3.478  0.639
2003 Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, Morgan D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutritional Neuroscience. 6: 153-62. PMID 12793519 DOI: 10.1080/1028415031000111282  0.66
2003 Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3745-51. PMID 12736345  0.675
2003 Boyett KW, DiCarlo G, Jantzen PT, Jackson J, O'Leary C, Wilcock D, Morgan D, Gordon MN. Increased fibrillar beta-amyloid in response to human clq injections into hippocampus and cortex of APP+PS1 transgenic mice. Neurochemical Research. 28: 83-93. PMID 12587666 DOI: 10.1023/A:1021600212829  0.829
2003 Kassed CA, Butler TL, Navidomskis MT, Gordon MN, Morgan D, Pennypacker KR. Mice expressing human mutant presenilin-1 exhibit decreased activation of NF-kappaB p50 in hippocampal neurons after injury. Brain Research. Molecular Brain Research. 110: 152-7. PMID 12573544 DOI: 10.1016/S0169-328X(02)00658-7  0.618
2003 Chaudhury AR, Gerecke KM, Wyss JM, Morgan DG, Gordon MN, Carroll SL. Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 62: 42-54. PMID 12528817 DOI: 10.1093/Jnen/62.1.42  0.425
2003 Morgan D, Jantzen P, Wilcock D, DiCarlo G, Ugen K, Gordon M. The Association of Microglial Activation and Amyloid Reduction in APP+PS1 Transgenic Mice Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 3: 27-32. DOI: 10.2174/1568013033358680  0.727
2003 Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation The Journal of Neuroscience. 23: 3745-3751. DOI: 10.1523/Jneurosci.23-09-03745.2003  0.668
2002 Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN. Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2246-54. PMID 11896164 DOI: 10.1523/Jneurosci.22-06-02246.2002  0.71
2002 Gordon MN, Holcomb LA, Jantzen PT, DiCarlo G, Wilcock D, Boyett KW, Connor K, Melachrino J, O'Callaghan JP, Morgan D. Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse. Experimental Neurology. 173: 183-95. PMID 11822882 DOI: 10.1006/Exnr.2001.7754  0.809
2001 Arendash GW, Gordon MN, Diamond DM, Austin LA, Hatcher JM, Jantzen P, DiCarlo G, Wilcock D, Morgan D. Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory. Dna and Cell Biology. 20: 737-44. PMID 11788052 DOI: 10.1089/10445490152717604  0.66
2001 Wilcock DM, Gordon MN, Ugen KE, Gottschall PE, DiCarlo G, Dickey C, Boyett KW, Jantzen PT, Connor KE, Melachrino J, Hardy J, Morgan D. Number of Abeta inoculations in APP+PS1 transgenic mice influences antibody titers, microglial activation, and congophilic plaque levels. Dna and Cell Biology. 20: 731-6. PMID 11788051 DOI: 10.1089/10445490152717596  0.823
2001 Dickey CA, Morgan DG, Kudchodkar S, Weiner DB, Bai Y, Cao C, Gordon MN, Ugen KE. Duration and specificity of humoral immune responses in mice vaccinated with the Alzheimer's disease-associated beta-amyloid 1-42 peptide. Dna and Cell Biology. 20: 723-9. PMID 11788050 DOI: 10.1089/10445490152717587  0.396
2001 DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D. Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice. Neurobiology of Aging. 22: 1007-12. PMID 11755009 DOI: 10.1016/S0197-4580(01)00292-5  0.693
2001 Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway. Experimental Neurology. 170: 227-43. PMID 11476589 DOI: 10.1006/Exnr.2001.7710  0.702
2001 Gordon MN, King DL, Diamond DM, Jantzen PT, Boyett KV, Hope CE, Hatcher JM, DiCarlo G, Gottschall WP, Morgan D, Arendash GW. Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice. Neurobiology of Aging. 22: 377-85. PMID 11378242 DOI: 10.1016/S0197-4580(00)00249-9  0.671
2001 Arendash GW, King DL, Gordon MN, Morgan D, Hatcher JM, Hope CE, Diamond DM. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Research. 891: 42-53. PMID 11164808 DOI: 10.1016/S0006-8993(00)03186-3  0.705
2001 Nilsson LNG, Bales KR, DiCarlo G, Gordon MN, Morgan D, Paul SM, Potter H. α-1-Antichymotrypsin Promotes β-Sheet Amyloid Plaque Deposition in a Transgenic Mouse Model of Alzheimer's Disease The Journal of Neuroscience. 21: 1444-1451. DOI: 10.1523/Jneurosci.21-05-01444.2001  0.719
2001 Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. Erratum: correction: Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature. 412: 660-660. DOI: 10.1038/35088102  0.614
2000 Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408: 982-5. PMID 11140686 DOI: 10.1038/35050116  0.687
2000 Holcomb LA, Gordon MN, Benkovic SA, Morgan DG. Aβ and perlecan in rat brain: Glial activation, gradual clearance and limited neurotoxicity Mechanisms of Ageing and Development. 112: 135-152. PMID 10690926 DOI: 10.1016/S0047-6374(99)00086-X  0.396
2000 Morgan D, Gordon MN, Diamond D, King D, Arendash G. Age-related memory deficits in doubly transgenic mice correlate with amyloid burden Neurobiology of Aging. 21: 18. DOI: 10.1016/S0197-4580(00)82758-X  0.641
2000 Nilsson LN, DiCarlo G, Gordon MN, Morgan DG, Bales KR, Paul SM, Lilly E, Potter H. The role of alpha-1-antichymotrypsin (ACT) in abeta-amyloidosis of Alzheimer's disease, as studied in novel trigenic PDAPP, mapoe-knockout, GFAP-hACT transgenic mice strains Neurobiology of Aging. 21: 88. DOI: 10.1016/S0197-4580(00)82620-2  0.381
1999 Wright KL, Morgan DG, Yu X, Goss JR, Salbaum JM, Duff K, Gordon MN. Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct. Journal of Molecular Neuroscience : Mn. 13: 111-20. PMID 10691298 DOI: 10.1385/Jmn:13:1-2:111  0.303
1999 Holcomb LA, Gordon MN, Jantzen P, Hsiao K, Duff K, Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behavior Genetics. 29: 177-85. PMID 10547924 DOI: 10.1023/A:1021691918517  0.694
1998 Morgan D, Holcomb L, Saad I, Gordon M, Mahin Maines. Impaired spatial navigation learning in transgenic mice over-expressing heme oxygenase-1 Brain Research. 808: 110-112. PMID 9795173 DOI: 10.1016/S0006-8993(98)00803-8  0.628
1998 Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nature Medicine. 4: 97-100. PMID 9427614 DOI: 10.1038/Nm0198-097  0.686
1996 Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature. 383: 710-3. PMID 8878479 DOI: 10.1038/383710A0  0.302
1996 Duft K, Gordon M. 440 Transgenic mice carrying presenilin and APP transgenes Neurobiology of Aging. 17: S110. DOI: 10.1016/S0197-4580(96)80442-8  0.408
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