| Year |
Citation |
Score |
| 2019 |
Zhou Y, Elmes MW, Sweeney J, Joseph O, Che J, Hsu HC, Li H, Deutsch DG, Ojima I, Kaczocha M, Rizzo RC. Identification of Fatty Acid Binding Protein 5 Inhibitors Through Similarity-based Screening. Biochemistry. PMID 31539229 DOI: 10.1021/Acs.Biochem.9B00625 |
0.671 |
|
| 2019 |
Kim J, Bogdan DM, Elmes MW, Awwa M, Yan S, Che J, Lee G, Deutsch DG, Rizzo RC, Kaczocha M, Ojima I. Incarvillateine produces antinociceptive and motor suppressive effects via adenosine receptor activation. Plos One. 14: e0218619. PMID 31237895 DOI: 10.1371/Journal.Pone.0218619 |
0.693 |
|
| 2019 |
Elmes MW, Prentis LE, McGoldrick LL, Giuliano CJ, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Studholme K, Deutsch DG, Rizzo RC, Glynn SE, Kaczocha M. FABP1 controls hepatic transport and biotransformation of Δ-THC. Scientific Reports. 9: 7588. PMID 31110286 DOI: 10.1038/S41598-019-44108-3 |
0.7 |
|
| 2018 |
Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, ... ... Deutsch DG, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. European Journal of Medicinal Chemistry. 154: 233-252. PMID 29803996 DOI: 10.1016/J.Ejmech.2018.04.050 |
0.678 |
|
| 2018 |
Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time. Behavioural Pharmacology. PMID 29570114 DOI: 10.1097/Fbp.0000000000000402 |
0.666 |
|
| 2018 |
Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M. Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531087 DOI: 10.1073/Pnas.1721339115 |
0.672 |
|
| 2018 |
Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels. Synapse (New York, N.Y.). PMID 29457656 DOI: 10.1002/Syn.22031 |
0.637 |
|
| 2017 |
Figueiredo A, Hamilton J, Marion M, Blum K, Kaczocha M, Haj-Dahmane S, Deutsch D, Thanos PK. Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice. Journal of Reward Deficiency Syndrome and Addiction Science. 3: 21-27. PMID 29367955 |
0.634 |
|
| 2017 |
Hsu HC, Tong S, Zhou Y, Elmes MW, Yan S, Kaczocha M, Deutsch DG, Rizzo RC, Ojima I, Li H. The antinociceptive agent SBFI-26 binds to anandamide transporters FABP5 and FABP7 at two different sites. Biochemistry. PMID 28632393 DOI: 10.1021/Acs.Biochem.7B00194 |
0.688 |
|
| 2017 |
Peng X, Studholme K, Kanjiya MP, Luk J, Bogdan D, Elmes MW, Carbonetti G, Tong S, Gary Teng YH, Rizzo RC, Li H, Deutsch DG, Ojima I, Rebecchi MJ, Puopolo M, et al. Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms. Molecular Pain. 13: 1744806917697007. PMID 28326944 DOI: 10.1177/1744806917697007 |
0.683 |
|
| 2017 |
Figueiredo A, Hamilton J, Marion M, Blum K, Kaczocha M, Haj-Dahmane S, Deutsch D, Thanos PK. Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice Journal of Reward Deficiency Syndrome and Addiction Science. 3. DOI: 10.17756/JRDSAS.2017-037 |
0.656 |
|
| 2016 |
Deutsch DG. A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs). Frontiers in Pharmacology. 7: 370. PMID 27790143 DOI: 10.3389/Fphar.2016.00370 |
0.508 |
|
| 2016 |
Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D, Kaczocha M. Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26. Frontiers in Psychiatry. 7: 54. PMID 27092087 DOI: 10.3389/Fpsyt.2016.00054 |
0.693 |
|
| 2015 |
Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The Journal of Biological Chemistry. 290: 8711-21. PMID 25666611 DOI: 10.1074/Jbc.M114.618447 |
0.728 |
|
| 2014 |
Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. Plos One. 9: e94200. PMID 24705380 DOI: 10.1371/Journal.Pone.0094200 |
0.808 |
|
| 2014 |
Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallographica. Section D, Biological Crystallography. 70: 290-8. PMID 24531463 DOI: 10.1107/S1399004713026795 |
0.71 |
|
| 2013 |
Leung K, Elmes MW, Glaser ST, Deutsch DG, Kaczocha M. Role of FAAH-like anandamide transporter in anandamide inactivation. Plos One. 8: e79355. PMID 24223930 DOI: 10.1371/Journal.Pone.0079355 |
0.804 |
|
| 2013 |
Tsuboi K, Ikematsu N, Uyama T, Deutsch DG, Tokumura A, Ueda N. Biosynthetic pathways of bioactive N-acylethanolamines in brain. Cns & Neurological Disorders Drug Targets. 12: 7-16. PMID 23394527 DOI: 10.2174/1871527311312010005 |
0.411 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. High throughput fluorescence displacement assay with NBD-stearate. Plos One. DOI: 10.1371/Journal.Pone.0050968.G008 |
0.594 |
|
| 2013 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Scheme demonstrating anandamide inactivation and FABP drug target. Plos One. DOI: 10.1371/Journal.Pone.0050968.G001 |
0.604 |
|
| 2012 |
Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. Plos One. 7: e50968. PMID 23236415 DOI: 10.1371/Journal.Pone.0050968 |
0.714 |
|
| 2012 |
Kaczocha M, Lin Q, Nelson LD, McKinney MK, Cravatt BF, London E, Deutsch DG. Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. Acs Chemical Neuroscience. 3: 364-8. PMID 22860204 DOI: 10.1021/Cn300001W |
0.671 |
|
| 2012 |
Kaczocha M, Vivieca S, Sun J, Glaser ST, Deutsch DG. Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors. The Journal of Biological Chemistry. 287: 3415-24. PMID 22170058 DOI: 10.1074/Jbc.M111.304907 |
0.816 |
|
| 2011 |
Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, Wang J, Deutsch DG, Burns MP, Ulloa NM, Tokumura A, Ueda N. Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochimica Et Biophysica Acta. 1811: 565-77. PMID 21801852 DOI: 10.1016/J.Bbalip.2011.07.009 |
0.729 |
|
| 2011 |
Wellner N, Tsuboi K, Madsen AN, Holst B, Diep TA, Nakao M, Tokumura A, Burns MP, Deutsch DG, Ueda N, Hansen HS. Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice. Biochimica Et Biophysica Acta. 1811: 508-12. PMID 21723414 DOI: 10.1016/J.Bbalip.2011.06.020 |
0.391 |
|
| 2011 |
Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. British Journal of Pharmacology. 163: 1329-43. PMID 21545414 DOI: 10.1111/J.1476-5381.2011.01364.X |
0.758 |
|
| 2010 |
Ulloa NM, Deutsch DG. Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. The Aaps Journal. 12: 197-201. PMID 20186507 DOI: 10.1208/S12248-010-9180-6 |
0.764 |
|
| 2010 |
Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. The Journal of Biological Chemistry. 285: 2796-806. PMID 19926788 DOI: 10.1074/Jbc.M109.058461 |
0.783 |
|
| 2009 |
Kaczocha M, Glaser ST, Deutsch DG. Identification of intracellular carriers for the endocannabinoid anandamide. Proceedings of the National Academy of Sciences of the United States of America. 106: 6375-80. PMID 19307565 DOI: 10.1073/Pnas.0901515106 |
0.81 |
|
| 2006 |
Hermann A, Kaczocha M, Deutsch DG. 2-Arachidonoylglycerol (2-AG) membrane transport: history and outlook. The Aaps Journal. 8: E409-12. PMID 16808043 DOI: 10.1007/Bf02854913 |
0.676 |
|
| 2006 |
Kaczocha M, Hermann A, Glaser ST, Bojesen IN, Deutsch DG. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. The Journal of Biological Chemistry. 281: 9066-75. PMID 16461355 DOI: 10.1074/Jbc.M509721200 |
0.8 |
|
| 2005 |
Glaser ST, Deutsch DG, Studholme KM, Zimov S, Yazulla S. Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. Visual Neuroscience. 22: 693-705. PMID 16469181 DOI: 10.1017/S0952523805226020 |
0.729 |
|
| 2005 |
Mechoulam R, Deutsch DG. Toward an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America. 102: 17541-2. PMID 16314567 DOI: 10.1073/Pnas.0508644102 |
0.49 |
|
| 2005 |
Deutsch DG. Design of on-target FAAH inhibitors. Chemistry & Biology. 12: 1157-8. PMID 16298293 DOI: 10.1016/J.Chembiol.2005.11.001 |
0.412 |
|
| 2005 |
Glaser ST, Kaczocha M, Deutsch DG. Anandamide transport: a critical review. Life Sciences. 77: 1584-604. PMID 15979096 DOI: 10.1016/J.Lfs.2005.05.007 |
0.814 |
|
| 2003 |
Glaser ST, Abumrad NA, Fatade F, Kaczocha M, Studholme KM, Deutsch DG. Evidence against the presence of an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America. 100: 4269-74. PMID 12655057 DOI: 10.1073/Pnas.0730816100 |
0.801 |
|
| 2003 |
Deutsch D, Ueda N, Yamamoto S. Erratum to “The fatty acid amide hydrolase (FAAH)” Prostaglandins, Leukotrienes and Essential Fatty Acids. 68: 69. DOI: 10.1016/S0952-3278(02)00227-2 |
0.334 |
|
| 2002 |
Deutsch DG, Ueda N, Yamamoto S. The fatty acid amide hydrolase (FAAH). Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 201-10. PMID 12052036 DOI: 10.1054/Plef.2001.0358 |
0.385 |
|
| 2001 |
Puffenbarger RA, Kapulina O, Howell JM, Deutsch DG. Characterization of the 5'-sequence of the mouse fatty acid amide hydrolase. Neuroscience Letters. 314: 21-4. PMID 11698137 DOI: 10.1016/S0304-3940(01)02274-1 |
0.34 |
|
| 2001 |
Day TA, Rakhshan F, Deutsch DG, Barker EL. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. Molecular Pharmacology. 59: 1369-75. PMID 11353795 DOI: 10.1124/Mol.59.6.1369 |
0.431 |
|
| 2001 |
Deutsch DG, Glaser ST, Howell JM, Kunz JS, Puffenbarger RA, Hillard CJ, Abumrad N. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. The Journal of Biological Chemistry. 276: 6967-73. PMID 11118429 DOI: 10.1074/Jbc.M003161200 |
0.76 |
|
| 2000 |
Ueda N, Puffenbarger RA, Yamamoto S, Deutsch DG. The fatty acid amide hydrolase (FAAH). Chemistry and Physics of Lipids. 108: 107-21. PMID 11106785 DOI: 10.1016/S0009-3084(00)00190-0 |
0.382 |
|
| 2000 |
Stefano GB, Bilfinger TV, Rialas CM, Deutsch DG. 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 42: 317-22. PMID 10987990 DOI: 10.1006/Phrs.2000.0702 |
0.313 |
|
| 1999 |
Yazulla S, Studholme KM, McIntosh HH, Deutsch DG. Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina. The Journal of Comparative Neurology. 415: 80-90. PMID 10540359 DOI: 10.1002/(Sici)1096-9861(19991206)415:1<80::Aid-Cne6>3.0.Co;2-H |
0.327 |
|
| 1999 |
Omeir RL, Arreaza G, Deutsch DG. Identification of two serine residues involved in catalysis by fatty acid amide hydrolase. Biochemical and Biophysical Research Communications. 264: 316-20. PMID 10529361 DOI: 10.1006/Bbrc.1999.1524 |
0.396 |
|
| 1998 |
Tsou K, Nogueron MI, Muthian S, Sañudo-Pena MC, Hillard CJ, Deutsch DG, Walker JM. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neuroscience Letters. 254: 137-40. PMID 10214976 DOI: 10.1016/S0304-3940(98)00700-9 |
0.315 |
|
| 1998 |
Di Marzo V, Deutsch DG. Biochemistry of the endogenous ligands of cannabinoid receptors. Neurobiology of Disease. 5: 386-404. PMID 9974173 DOI: 10.1006/Nbdi.1998.0214 |
0.377 |
|
| 1998 |
Bilfinger TV, Salzet M, Fimiani C, Deutsch DG, Tramu G, Stefano GB. Pharmacological evidence for anandamide amidase in human cardiac and vascular tissues. International Journal of Cardiology. 64: S15-22. PMID 9687088 DOI: 10.1016/S0167-5273(98)00031-X |
0.31 |
|
| 1997 |
Arreaza G, Devane WA, Omeir RL, Sajnani G, Kunz J, Cravatt BF, Deutsch DG. The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine. Neuroscience Letters. 234: 59-62. PMID 9347946 DOI: 10.1016/S0304-3940(97)00673-3 |
0.362 |
|
| 1997 |
Deutsch DG, Goligorsky MS, Schmid PC, Krebsbach RJ, Schmid HH, Das SK, Dey SK, Arreaza G, Thorup C, Stefano G, Moore LC. Production and physiological actions of anandamide in the vasculature of the rat kidney. The Journal of Clinical Investigation. 100: 1538-46. PMID 9294122 DOI: 10.1172/Jci119677 |
0.336 |
|
| 1997 |
Deutsch DG, Lin S, Hill WA, Morse KL, Salehani D, Arreaza G, Omeir RL, Makriyannis A. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. Biochemical and Biophysical Research Communications. 231: 217-21. PMID 9070252 DOI: 10.1006/Bbrc.1997.6072 |
0.414 |
|
| 1997 |
Deutsch DG, Omeir R, Arreaza G, Salehani D, Prestwich GD, Huang Z, Howlett A. Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase. Biochemical Pharmacology. 53: 255-60. PMID 9065728 DOI: 10.1016/S0006-2952(96)00830-1 |
0.406 |
|
| 1994 |
Koutek B, Prestwich GD, Howlett AC, Chin SA, Salehani D, Akhavan N, Deutsch DG. Inhibitors of arachidonoyl ethanolamide hydrolysis. The Journal of Biological Chemistry. 269: 22937-40. PMID 8083191 |
0.34 |
|
| 1993 |
Deutsch DG, Chin SA. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochemical Pharmacology. 46: 791-6. PMID 8373432 DOI: 10.1016/0006-2952(93)90486-G |
0.411 |
|
| 1984 |
Deutsch DG, Koul O, Kersten RS. Phencyclidine and analogues: effects on brain protein synthesis. Journal of Neurochemistry. 42: 407-11. PMID 6693876 DOI: 10.1111/J.1471-4159.1984.Tb02692.X |
0.339 |
|
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