Ruth A. Keri - Publications

Affiliations: 
Pharmacology Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Pharmacology, Oncology, Cell Biology

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pai CP, Wang H, Seachrist DD, Agarwal N, Adams JA, Liu Z, Keri RA, Cao K, Schiemann WP, Kao HY. The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer. Cell Death and Differentiation. PMID 38627584 DOI: 10.1038/s41418-024-01294-6  0.542
2023 Caputo A, Vipparthi K, Bazeley P, Downs-Kelly E, McIntire P, Duckworth LA, Ni Y, Hu B, Keri RA, Karaayvaz M. Spatial transcriptomics suggests that alterations occur in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers. Molecular Cancer Research : McR. PMID 37878345 DOI: 10.1158/1541-7786.MCR-23-0489  0.409
2023 Kao HY, Pai CP, Wang H, Agarwal N, Adams J, Liu Z, Seachrist D, Keri R, Schiemann W. The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer. Research Square. PMID 37720048 DOI: 10.21203/rs.3.rs-3266720/v1  0.544
2023 Bobbitt JR, Seachrist D, Keri RA. Chromatin organization and transcriptional programming of breast cancer cell identity. Endocrinology. PMID 37394919 DOI: 10.1210/endocr/bqad100  0.459
2023 Caputo A, Vipparthi K, Bazeley P, Downs-Kelly E, McIntire P, Ni Y, Hu B, Keri RA, Karaayvaz M. Alterations in the preneoplastic breast microenvironment of mutation carriers revealed by spatial transcriptomics. Biorxiv : the Preprint Server For Biology. PMID 37292816 DOI: 10.1101/2023.05.24.542078  0.413
2023 Anstine LJ, Majmudar PR, Aponte A, Singh S, Zhao R, Weber Bonk KL, Abdul-Karim FW, Valentine M, Seachrist DD, Grenell-Nickelson KE, Cuellar-Vite L, Sizemore GM, Sizemore ST, Webb BM, Thompson CL, ... Keri RA, et al. TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis. Cancer Research. PMID 36696357 DOI: 10.1158/0008-5472.CAN-22-3133  0.504
2022 Cuellar-Vite L, Weber-Bonk KL, Abdul-Karim FW, Booth CN, Keri RA. Focal Adhesion Kinase Provides a Collateral Vulnerability That Can Be Leveraged to Improve mTORC1 Inhibitor Efficacy. Cancers. 14. PMID 35884439 DOI: 10.3390/cancers14143374  0.569
2021 Seachrist DD, Anstine LJ, Keri RA. FOXA1: A Pioneer of Nuclear Receptor Action in Breast Cancer. Cancers. 13. PMID 34680352 DOI: 10.3390/cancers13205205  0.451
2021 Piemonte KM, Anstine LJ, Keri RA. Centrosome Aberrations as Drivers of Chromosomal Instability in Breast Cancer. Endocrinology. 162. PMID 34606589 DOI: 10.1210/endocr/bqab208  0.425
2021 Webb BM, Bryson BL, Williams-Medina E, Bobbitt JR, Seachrist DD, Anstine LJ, Keri RA. TGF-β/Activin Signaling Promotes CDK7 Inhibitor Resistance in Triple Negative Breast Cancer Cells through Upregulation of Multidrug Transporters. The Journal of Biological Chemistry. 101162. PMID 34481843 DOI: 10.1016/j.jbc.2021.101162  0.326
2021 Adorno-Cruz V, Hoffmann AD, Liu X, Dashzeveg NK, Taftaf R, Wray B, Keri RA, Liu H. promotes expression of and in enhancing breast cancer stemness and metastasis. Genes & Diseases. 8: 493-508. PMID 34179312 DOI: 10.1016/j.gendis.2020.01.015  0.508
2020 Sahni JM, Gayle SS, Bonk KLW, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA. Correction: Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of aurora kinases. The Journal of Biological Chemistry. 295: 9266. PMID 33516519 DOI: 10.1074/jbc.AAC120.014699  0.811
2020 Sahni JM, Gayle SS, Bonk KLW, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA. Correction: Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of aurora kinases. The Journal of Biological Chemistry. 295: 9266. PMID 32620694 DOI: 10.1074/jbc.AAC120.014699  0.811
2020 Turaga SM, Silver DJ, Bayik D, Paouri E, Peng S, Lauko A, Alban TJ, Borjini N, Stanko S, Naik U, Keri RA, Connor JR, Barnholtz-Sloan JS, Rubin JB, Berens M, et al. JAM-A functions as a female microglial tumor suppressor in glioblastoma. Neuro-Oncology. PMID 32592484 DOI: 10.1093/Neuonc/Noaa148  0.434
2020 Seachrist DD, Hannigan MM, Ingles NN, Webb BM, Weber-Bonk KL, Yu P, Bebek G, Singh S, Sizemore ST, Varadan V, Licatalosi DD, Keri RA. --The transcriptional repressor BCL11A promotes breast cancer metastasis. The Journal of Biological Chemistry. PMID 32576660 DOI: 10.1074/Jbc.Ra120.014018  0.527
2020 Roberts MS, Anstine LJ, Finke VS, Bryson BL, Webb BM, Weber-Bonk KL, Seachrist DD, Majmudar PR, Keri RA. KLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene. Breast Cancer Research : Bcr. 22: 66. PMID 32552913 DOI: 10.1186/S13058-020-01305-7  0.48
2020 Roberts MS, Sahni JM, Schrock MS, Piemonte KM, Weber-Bonk KL, Seachrist DD, Avril S, Anstine LJ, Singh S, Sizemore ST, Varadan V, Summers MK, Keri RA. LIN9 and NEK2 are core regulators of mitotic fidelity that can be therapeutically targeted to overcome taxane resistance. Cancer Research. PMID 32054769 DOI: 10.1158/0008-5472.Can-19-3466  0.458
2020 Adorno-Cruz V, Hoffmann A, Liu X, Keri R, Liu H. Abstract P3-02-15: Integrin a2 promotes stemness and lung metastasis in triple negative breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-02-15  0.565
2020 Webb BM, Shively M, Piemonte K, Sahni JM, Keri RA. Abstract P2-04-01: Cyclin dependent kinase 7 ( CDK7) inhibition promotes genomic instability and mitotic catastrophe in triple negative breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P2-04-01  0.558
2020 Adorno-Cruz V, Hoffmann AD, Liu X, Dashzeveg NK, Taftaf R, Wray B, Keri RA, Liu H. ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis Genes and Diseases. DOI: 10.1016/J.Gendis.2020.01.015  0.577
2019 Shukla S, Jandzinski M, Wang C, Gong X, Bonk KW, Keri RA, Steinmetz NF. A Viral Nanoparticle Cancer Vaccine Delays Tumor Progression and Prolongs Survival in a HER2 Tumor Mouse Model. Advanced Therapeutics. 2. PMID 33855164 DOI: 10.1002/adtp.201800139  0.315
2019 Anstine LJ, Keri R. A new view of the mammary epithelial hierarchy and its implications for breast cancer initiation and metastasis. Journal of Cancer Metastasis and Treatment. 5. PMID 32395618 DOI: 10.20517/2394-4722.2019.24  0.38
2019 Seachrist DD, Keri RA. The Activin Social Network: Activin, Inhibin and Follistatin in Breast Development and Cancer. Endocrinology. PMID 30874767 DOI: 10.1210/En.2019-00015  0.434
2019 Thakur V, Zhang K, Savadelis A, Zmina P, Aguila B, Welford SM, Abdul-Karim F, Bonk KW, Keri RA, Bedogni B. The membrane tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo- and radiotherapy responses of breast cancer. Cancer Letters. 443: 115-124. PMID 30502358 DOI: 10.1016/J.Canlet.2018.11.031  0.488
2019 Shively, Gayle S, Sahni J, Keri R. Abstract P5-03-01: LIN9 regulation of NEK2 underlies taxol resistance in triple-negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P5-03-01  0.546
2019 Webb B, Sahni J, Keri R. Abstract P4-07-06: Cyclin dependent kinase 7 (CDK7) inhibition with THZ1 induces mitotic failure and increases genomic instability in triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P4-07-06  0.581
2019 Ingles NN, Seachrist D, Keri R. Abstract 172: BCL11A regulation of extracellular matrix genes may be necessary for invasion of triple-negative breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-172  0.514
2018 Gayle SS, Sahni JM, Webb BM, Weber-Bonk KL, Shively MS, Spina R, Bar EE, Summers MK, Keri RA. Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells. The Journal of Biological Chemistry. PMID 30482844 DOI: 10.1074/Jbc.Ra118.004712  0.485
2018 Hashemi-Sadraei N, Müller-Greven GM, Abdul-Karim FW, Ulasov I, Downs-Kelly E, Burgett ME, Lauko A, Qadan MA, Weil RJ, Ahluwalia MS, Du L, Prayson RA, Chao ST, Budd TG, Barnholtz-Sloan J, ... ... Keri RA, et al. Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer. Journal of Neuro-Oncology. PMID 30094720 DOI: 10.1007/S11060-018-2959-5  0.559
2018 Tsung K, Thompson CL, Knight JM, Maximuk S, Sadri N, Gilmore H, Keri RA, Vinayak S, Harris L, Silverman P. A breast multi-disciplinary genomic tumor board is feasible and can provide timely and impactful recommendations. The Breast Journal. PMID 29517142 DOI: 10.1111/Tbj.13027  0.457
2018 Yang X, Pan Y, Qiu Z, Du Z, Zhang Y, Fa P, Gorityala S, Ma S, Li S, Chen C, Wang H, Xu Y, Yan C, Keri RA, Ma Z, et al. RNF126 as a biomarker of a poor prognosis in invasive breast cancer and CHK1 inhibitor efficacy in breast cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29326282 DOI: 10.1158/1078-0432.Ccr-17-2242  0.511
2018 Seachrist DD, Ingles NN, Hannigan MM, Licatalosi DD, Keri RA. Abstract 32: BCL11A is necessary for the expression of extracellular matrix genes and metastatic progression of triple-negative breast cancer Cancer Research. 78: 32-32. DOI: 10.1158/1538-7445.Am2018-32  0.533
2018 Liao P, Yori J, Keri R, Koyuturk M, Barnholtz-Sloan J. Abstract 2262: Inference of kinase activity for cancer phosphoproteomics using substrate prediction scores Cancer Research. 78: 2262-2262. DOI: 10.1158/1538-7445.Am2018-2262  0.779
2017 Sahni JM, Keri RA. Targeting bromodomain and extraterminal proteins in breast cancer. Pharmacological Research. PMID 29154989 DOI: 10.1016/J.Phrs.2017.11.015  0.604
2017 Sahni JM, Gayle SS, Webb B, Weber-Bonk KL, Seachrist DD, Singh S, Sizemore ST, Restrepo NA, Bebek G, Scacheri P, Varadan V, Summers MK, Keri RA. Mitotic vulnerability in triple-negative breast cancer associated with LIN9 is targetable with BET inhibitors. Cancer Research. PMID 28807940 DOI: 10.1158/0008-5472.Can-17-1571  0.585
2017 Morrison CD, Chang JC, Keri RA, Schiemann WP. Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers. Cell Death & Disease. 8: e2899. PMID 28661474 DOI: 10.1038/Cddis.2017.294  0.507
2017 Seachrist DD, Sizemore ST, Johnson E, Abdul-Karim FW, Weber Bonk KL, Keri RA. Follistatin is a metastasis suppressor in a mouse model of HER2-positive breast cancer. Breast Cancer Research : Bcr. 19: 66. PMID 28583174 DOI: 10.1186/S13058-017-0857-Y  0.561
2017 Cohen AJ, Saiakhova A, Corradin O, Luppino JM, Lovrenert K, Bartels CF, Morrow JJ, Mack SC, Dhillon G, Beard L, Myeroff L, Kalady MF, Willis J, Bradner JE, Keri RA, et al. Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome. Nature Communications. 8: 14400. PMID 28169291 DOI: 10.1038/Ncomms14400  0.335
2016 Sahni JM, Gayle SS, Weber-Bonk KL, Cuellar Vite L, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA. Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of Aurora kinases. The Journal of Biological Chemistry. PMID 27650498 DOI: 10.1074/Jbc.M116.738666  0.814
2016 Morrison CD, Allington TM, Thompson CL, Gilmore HL, Chang JC, Keri RA, Schiemann WP. c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression. Oncotarget. PMID 27626309 DOI: 10.18632/Oncotarget.11909  0.472
2016 Brancato JM, Gayle S, Weber-Bonk K, Summers M, Bebek G, Keri R. Abstract 4647: BET protein inhibition blocks growth of triple-negative breast cancer by inducing mitotic and cytokinetic dysfunction Cancer Research. 76: 4647-4647. DOI: 10.1158/1538-7445.Am2016-4647  0.605
2015 Yehia L, Niazi F, Ni Y, Ngeow J, Sankunny M, Liu Z, Wei W, Mester JL, Keri RA, Zhang B, Eng C. Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer. American Journal of Human Genetics. 97: 661-676. PMID 26522472 DOI: 10.1016/J.Ajhg.2015.10.001  0.453
2015 Seachrist DD, Bonk KW, Ho SM, Prins GS, Soto AM, Keri RA. A review of the carcinogenic potential of bisphenol A. Reproductive Toxicology (Elmsford, N.Y.). PMID 26493093 DOI: 10.1016/J.Reprotox.2015.09.006  0.38
2014 Yori JL, Lozada KL, Seachrist DD, Mosley JD, Abdul-Karim FW, Booth CN, Flask CA, Keri RA. Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression. Cancer Research. 74: 4762-71. PMID 25023728 DOI: 10.1158/0008-5472.Can-13-3627  0.832
2014 Sizemore GM, Sizemore ST, Seachrist DD, Keri RA. GABA(A) receptor pi (GABRP) stimulates basal-like breast cancer cell migration through activation of extracellular-regulated kinase 1/2 (ERK1/2). The Journal of Biological Chemistry. 289: 24102-13. PMID 25012653 DOI: 10.1074/Jbc.M114.593582  0.596
2014 Sizemore ST, Sizemore GM, Booth CN, Thompson CL, Silverman P, Bebek G, Abdul-Karim FW, Avril S, Keri RA. Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors. Breast Cancer Research and Treatment. 146: 25-40. PMID 24847890 DOI: 10.1007/S10549-014-2989-4  0.52
2014 Peiris PM, Tam M, Vicente P, Abramowski A, Toy R, Bauer L, Mayer A, Pansky J, Doolittle E, Tucci S, Schmidt E, Shoup C, Rao S, Murray K, Gopalakrishnan R, ... Keri RA, et al. On-command drug release from nanochains inhibits growth of breast tumors. Pharmaceutical Research. 31: 1460-8. PMID 23934254 DOI: 10.1007/S11095-013-1102-8  0.479
2013 Sizemore GM, Sizemore ST, Pal B, Booth CN, Seachrist DD, Abdul-Karim FW, Kume T, Keri RA. FOXC1 is enriched in the mammary luminal progenitor population, but is not necessary for mouse mammary ductal morphogenesis. Biology of Reproduction. 89: 10. PMID 23677979 DOI: 10.1095/Biolreprod.113.108001  0.552
2013 Asrani K, Keri RA, Galisteo R, Brown SA, Morgan SJ, Ghosh A, Tran NL, Winkles JA. The HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression. Molecular Cancer Research : McR. 11: 393-404. PMID 23378579 DOI: 10.1158/1541-7786.Mcr-12-0542  0.604
2013 Bernardo GM, Bebek G, Ginther CL, Sizemore ST, Lozada KL, Miedler JD, Anderson LA, Godwin AK, Abdul-Karim FW, Slamon DJ, Keri RA. FOXA1 represses the molecular phenotype of basal breast cancer cells. Oncogene. 32: 554-63. PMID 22391567 DOI: 10.1038/Onc.2012.62  0.577
2013 Yori JL, Lozada K, Seachrist DD, Mosley J, Abdul-Karim FW, Booth CN, Flask CA, Keri RA. Abstract LB-221: Inhibition of rapamycin-induced feedback activation of AKT with dasatinib induces complete tumor regression in a preclinical model of breast cancer. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-221  0.837
2012 Peiris PM, Toy R, Doolittle E, Pansky J, Abramowski A, Tam M, Vicente P, Tran E, Hayden E, Camann A, Mayer A, Erokwu BO, Berman Z, Wilson D, Baskaran H, ... ... Keri RA, et al. Imaging metastasis using an integrin-targeting chain-shaped nanoparticle. Acs Nano. 6: 8783-95. PMID 23005348 DOI: 10.1021/Nn303833P  0.325
2012 Seachrist DD, Johnson E, Magee C, Clay CM, Graham JK, Veeramachaneni DN, Keri RA. Overexpression of follistatin in the mouse epididymis disrupts fluid resorption and sperm transit in testicular excurrent ducts. Biology of Reproduction. 87: 41. PMID 22649074 DOI: 10.1095/Biolreprod.111.097527  0.347
2012 Sizemore ST, Keri RA. The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression. The Journal of Biological Chemistry. 287: 24631-40. PMID 22645147 DOI: 10.1074/Jbc.M112.375865  0.53
2012 Peiris PM, Bauer L, Toy R, Tran E, Pansky J, Doolittle E, Schmidt E, Hayden E, Mayer A, Keri RA, Griswold MA, Karathanasis E. Enhanced delivery of chemotherapy to tumors using a multicomponent nanochain with radio-frequency-tunable drug release. Acs Nano. 6: 4157-68. PMID 22486623 DOI: 10.1021/Nn300652P  0.316
2012 Bernardo GM, Keri RA. FOXA1: a transcription factor with parallel functions in development and cancer. Bioscience Reports. 32: 113-30. PMID 22115363 DOI: 10.1042/Bsr20110046  0.446
2011 Beach JR, Hussey GS, Miller TE, Chaudhury A, Patel P, Monslow J, Zheng Q, Keri RA, Reizes O, Bresnick AR, Howe PH, Egelhoff TT. Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition. Proceedings of the National Academy of Sciences of the United States of America. 108: 17991-6. PMID 22025714 DOI: 10.1073/Pnas.1106499108  0.341
2011 Yori JL, Seachrist DD, Johnson E, Lozada KL, Abdul-Karim FW, Chodosh LA, Schiemann WP, Keri RA. Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia (New York, N.Y.). 13: 601-10. PMID 21750654 DOI: 10.1593/Neo.11260  0.841
2011 Weber Lozada K, Keri RA. Bisphenol A increases mammary cancer risk in two distinct mouse models of breast cancer. Biology of Reproduction. 85: 490-7. PMID 21636739 DOI: 10.1095/Biolreprod.110.090431  0.561
2010 Montañez-Wiscovich ME, Shelton MD, Seachrist DD, Lozada KL, Johnson E, Miedler JD, Abdul-Karim FW, Visvader JE, Keri RA. Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells. The Journal of Pathology. 222: 271-81. PMID 20814902 DOI: 10.1002/Path.2762  0.561
2010 Johnson E, Seachrist DD, DeLeon-Rodriguez CM, Lozada KL, Miedler J, Abdul-Karim FW, Keri RA. HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. The Journal of Biological Chemistry. 285: 29491-501. PMID 20595387 DOI: 10.1074/Jbc.M110.136770  0.587
2010 Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, Godwin AK, Korach KS, Visvader JE, Kaestner KH, Abdul-Karim FW, Montano MM, Keri RA. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (Cambridge, England). 137: 2045-54. PMID 20501593 DOI: 10.1242/Dev.043299  0.588
2010 Yori JL, Johnson E, Zhou G, Jain MK, Keri RA. Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression. The Journal of Biological Chemistry. 285: 16854-63. PMID 20356845 DOI: 10.1074/Jbc.M110.114546  0.803
2010 Lozada KW, Keri RA. Bisphenol A Increases Mammary Cancer Risk in Multiple Murine Models of Breast Cancer. Biology of Reproduction. 83: 75-75. DOI: 10.1093/Biolreprod/83.S1.75  0.538
2009 Montañez-Wiscovich ME, Seachrist DD, Landis MD, Visvader J, Andersen B, Keri RA. LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression. Oncogene. 28: 3608-18. PMID 19648968 DOI: 10.1038/Onc.2009.221  0.821
2009 Mosley JD, Keri RA. Intrinsic bias in breast cancer gene expression data sets Bmc Cancer. 9. PMID 19563679 DOI: 10.1186/1471-2407-9-214  0.444
2009 Peters GA, Seachrist DD, Keri RA, Sen GC. The double-stranded RNA-binding protein, PACT, is required for postnatal anterior pituitary proliferation. Proceedings of the National Academy of Sciences of the United States of America. 106: 10696-701. PMID 19541653 DOI: 10.1073/Pnas.0900735106  0.35
2008 Mosley JD, Keri RA. Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists. Bmc Medical Genomics. 1: 11. PMID 18439262 DOI: 10.1186/1755-8794-1-11  0.376
2008 Milliken EL, Lozada KL, Johnson E, Landis MD, Seachrist DD, Whitten I, Sutton AL, Abdul-Karim FW, Keri RA. Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer. Oncogene. 27: 1759-66. PMID 17891171 DOI: 10.1038/Sj.Onc.1210815  0.823
2007 Sutton AL, Keri RA. The pleiotropic effects of excessive luteinizing hormone secretion in transgenic mice. Seminars in Reproductive Medicine. 25: 360-7. PMID 17710732 DOI: 10.1055/S-2007-984742  0.335
2007 Mosley JD, Poirier JT, Seachrist DD, Landis MD, Keri RA. Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. Molecular Cancer Therapeutics. 6: 2188-97. PMID 17699716 DOI: 10.1158/1535-7163.Mct-07-0235  0.818
2007 Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei Z, Rao CV, Perry G, Keri RA, Smith MA. Increases in luteinizing hormone are associated with declines in cognitive performance. Molecular and Cellular Endocrinology. 269: 107-11. PMID 17376589 DOI: 10.1016/J.Mce.2006.06.013  0.749
2006 Mosley JD, Keri RA. Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis Biochemical and Biophysical Research Communications. 348: 1174-1183. PMID 16905118 DOI: 10.1016/J.Bbrc.2006.07.176  0.32
2006 Landis MD, Seachrist DD, Abdul-Karim FW, Keri RA. Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors. Oncogene. 25: 3325-34. PMID 16434967 DOI: 10.1038/Sj.Onc.1209365  0.767
2005 Milliken EL, Zhang X, Flask C, Duerk JL, MacDonald PN, Keri RA. EB1089, a vitamin D receptor agonist, reduces proliferation and decreases tumor growth rate in a mouse model of hormone-induced mammary cancer. Cancer Letters. 229: 205-15. PMID 16115727 DOI: 10.1016/J.Canlet.2005.06.044  0.838
2005 Landis MD, Seachrist DD, Montañez-Wiscovich ME, Danielpour D, Keri RA. Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice. Oncogene. 24: 5173-90. PMID 15897883 DOI: 10.1038/Sj.Onc.1208712  0.761
2004 Knostman KA, Cho JY, Ryu KY, Lin X, McCubrey JA, Hla T, Liu CH, Di Carlo E, Keri R, Zhang M, Hwang DY, Kisseberth WC, Capen CC, Jhiang SM. Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer. The Journal of Clinical Endocrinology and Metabolism. 89: 5196-203. PMID 15472226 DOI: 10.1210/Jc.2004-0907  0.549
2003 Mann RJ, Keri RA, Nilson JH. Consequences of elevated luteinizing hormone on diverse physiological systems: use of the LHbetaCTP transgenic mouse as a model of ovarian hyperstimulation-induced pathophysiology. Recent Progress in Hormone Research. 58: 343-75. PMID 12795427 DOI: 10.1210/Rp.58.1.343  0.466
2003 Mikola M, Kero J, Nilson JH, Keri RA, Poutanen M, Huhtaniemi I. High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-alpha-subunit promoter/Simian virus 40 T-antigen fusion gene. Oncogene. 22: 3269-78. PMID 12761497 DOI: 10.1038/Sj.Onc.1206518  0.394
2002 Milliken EL, Ameduri RK, Landis MD, Behrooz A, Abdul-Karim FW, Keri RA. Ovarian hyperstimulation by LH leads to mammary gland hyperplasia and cancer predisposition in transgenic mice. Endocrinology. 143: 3671-80. PMID 12193583 DOI: 10.1210/En.2002-220228  0.822
2002 Owens GE, Keri RA, Nilson JH. Ovulatory surges of human CG prevent hormone-induced granulosa cell tumor formation leading to the identification of tumor-associated changes in the transcriptome. Molecular Endocrinology (Baltimore, Md.). 16: 1230-42. PMID 12040011 DOI: 10.1210/Mend.16.6.0850  0.431
2001 Quirk CC, Lozada KL, Keri RA, Nilson JH. A single Pitx1 binding site is essential for activity of the LHbeta promoter in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 15: 734-46. PMID 11328855 DOI: 10.1210/Mend.15.5.0628  0.328
2000 Keri RA, Bachmann DJ, Behrooz A, Herr BD, Ameduri RK, Quirk CC, Nilson JH. An NF-Y binding site is important for basal, but not gonadotropin-releasing hormone-stimulated, expression of the luteinizing hormone beta subunit gene. The Journal of Biological Chemistry. 275: 13082-8. PMID 10777613 DOI: 10.1074/Jbc.275.17.13082  0.343
2000 Kero J, Poutanen M, Zhang FP, Rahman N, McNicol AM, Nilson JH, Keri RA, Huhtaniemi IT. Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex. The Journal of Clinical Investigation. 105: 633-41. PMID 10712435 DOI: 10.1172/Jci7716  0.349
2000 Keri RA, Lozada KL, Abdul-Karim FW, Nadeau JH, Nilson JH. Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition. Proceedings of the National Academy of Sciences of the United States of America. 97: 383-7. PMID 10618427 DOI: 10.1073/Pnas.97.1.383  0.427
1997 Farmerie TA, Abbud RA, Budworth PR, Clay CM, Keri RA, McDowell KJ, Wolfe MW, Nilson JH. Characterization of the equine glycoprotein hormone alpha-subunit gene reveals divergence in the mechanism of pituitary and placental expression. Biology of Reproduction. 57: 1104-14. PMID 9369177 DOI: 10.1095/Biolreprod57.5.1104  0.308
1994 Keri RA, Wolfe MW, Saunders TL, Anderson I, Kendall SK, Wagner T, Yeung J, Gorski J, Nett TM, Camper SA. The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 8: 1807-16. PMID 7708066 DOI: 10.1210/Mend.8.12.7708066  0.307
1991 Keri RA, Andersen B, Kennedy GC, Hamernik DL, Clay CM, Brace AD, Nett TM, Notides AC, Nilson JH. Estradiol inhibits transcription of the human glycoprotein hormone alpha-subunit gene despite the absence of a high affinity binding site for estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 5: 725-33. PMID 1712910 DOI: 10.1210/Mend-5-5-725  0.302
1991 Kendall SK, Saunders TL, Jin L, Lloyd RV, Glode LM, Nett TM, Keri RA, Nilson JH, Camper SA. Targeted ablation of pituitary gonadotropes in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 5: 2025-36. PMID 1665205 DOI: 10.1210/Mend-5-12-2025  0.335
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