☰

Justin R Cross - Publications

Affiliations: 
2011- Cell Metabolism Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, United States 
Website:
https://www.mskcc.org/research/ski/profile/justin-cross
Tree Info Similar researchers PubMed Report error

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Eskandari R, Kim N, Mamakhanyan A, Saoi M, Zhang G, Berisaj M, Granlund KL, Poot AJ, Cross J, Thompson CB, Keshari KR. Hyperpolarized [5-C,4,4-H,5-N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120595119. PMID 35512101 DOI: 10.1073/pnas.2120595119  0.401
2021 Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, et al. Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews. Cancer. PMID 34764459 DOI: 10.1038/s41568-021-00417-2  0.558
2021 Zhu J, Schwörer S, Berisa M, Kyung YJ, Ryu KW, Yi J, Jiang X, Cross JR, Thompson CB. Mitochondrial NADP(H) generation is essential for proline biosynthesis. Science (New York, N.Y.). PMID 33888598 DOI: 10.1126/science.abd5491  0.427
2020 Pavlova NN, King B, Josselsohn RH, Violante S, Macera VL, Vardhana SA, Cross JR, Thompson CB. Translation in amino acid-poor environments is limited by tRNA charging. Elife. 9. PMID 33289483 DOI: 10.7554/eLife.62307  0.411
2020 Vardhana SA, Hwee MA, Berisa M, Wells DK, Yost KE, King B, Smith M, Herrera PS, Chang HY, Satpathy AT, van den Brink MRM, Cross JR, Thompson CB. Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Nature Immunology. PMID 32661364 DOI: 10.1038/S41590-020-0725-2  0.477
2020 Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature. 581: 475-479. PMID 32461639 DOI: 10.1038/S41586-020-2193-0  0.362
2020 Cai Y, Rattray NJW, Zhang Q, Mironova V, Santos-Neto A, Hsu KS, Rattray Z, Cross JR, Zhang Y, Paty PB, Khan SA, Johnson CH. Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype. Scientific Reports. 10: 4905. PMID 32184446 DOI: 10.1038/S41598-020-61851-0  0.316
2020 Schwörer S, Berisa M, Violante S, Qin W, Zhu J, Hendrickson RC, Cross JR, Thompson CB. Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress. The Embo Journal. e103334. PMID 32134147 DOI: 10.15252/Embj.2019103334  0.486
2020 Chen CC, Li B, Millman SE, Chen C, Li X, Morris JP, Mayle A, Ho YJ, Loizou E, Liu H, Qin W, Shah H, Violante S, Cross JR, Lowe SW, et al. Vitamin B6 Addiction in Acute Myeloid Leukemia. Cancer Cell. 37: 71-84.e7. PMID 31935373 DOI: 10.1016/J.Ccell.2019.12.002  0.368
2019 Zhu J, Berisa M, Schwörer S, Qin W, Cross JR, Thompson CB. Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell Metabolism. PMID 31607565 DOI: 10.1016/J.Cmet.2019.09.009  0.542
2019 Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, et al. Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis. Cancer Cell. 35: 916-931.e9. PMID 31185214 DOI: 10.1016/J.Ccell.2019.05.002  0.386
2019 Singh K, Lin J, Zhong Y, Burčul A, Mohan P, Jiang M, Sun L, Yong-Gonzalez V, Viale A, Cross JR, Hendrickson RC, Rätsch G, Ouyang Z, Wendel HG. c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma. The Journal of Experimental Medicine. PMID 31142587 DOI: 10.1084/Jem.20181726  0.325
2019 Violante S, Berisa M, Thomas TH, Cross JR. Stable Isotope Tracers for Metabolic Pathway Analysis. Methods in Molecular Biology (Clifton, N.J.). 1978: 269-283. PMID 31119669 DOI: 10.1007/978-1-4939-9236-2_17  0.308
2018 Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N, Durani V, Liu H, Taylor J, Farnoud N, Papaemmanuil E, ... Cross JR, et al. Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. Nature. PMID 29950729 DOI: 10.1038/S41586-018-0251-7  0.471
2017 Vitiello GA, Medina BD, Zeng S, Bowler TG, Zhang JQ, Loo JK, Param NJ, Liu M, Moral JA, Zhao JN, Rossi F, Antonescu CR, Balachandran VP, Cross JR, DeMatteo RP. Mitochondrial inhibition augments the efficacy of imatinib by resetting the metabolic phenotype of gastrointestinal stromal tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29246941 DOI: 10.1158/1078-0432.Ccr-17-2697  0.371
2017 Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, et al. Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence. Nature Genetics. PMID 29180699 DOI: 10.1038/S41588-017-0001-Z  0.486
2017 Salamanca-Cardona L, Shah H, Poot AJ, Correa FM, Di Gialleonardo V, Lui H, Miloushev VZ, Granlund KL, Tee SS, Cross JR, Thompson CB, Keshari KR. In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors. Cell Metabolism. PMID 29056515 DOI: 10.1016/J.Cmet.2017.10.001  0.516
2017 Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, et al. Commensal bacteria make GPCR ligands that mimic human signalling molecules. Nature. PMID 28854168 DOI: 10.1038/Nature23874  0.31
2017 Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, Rustenburg AS, Salah S, Gunner MR, Chodera JD, Cross JR, Thompson CB. L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH. Nature Chemical Biology. PMID 28263965 DOI: 10.1038/Nchembio.2307  0.5
2017 Li M, Chiang Y, Lyssiotis C, Teater M, Shen H, Wang L, Hong JY, Jin H, Duy C, Mistry S, Cerchietti L, Cross J, Cantley L, Lin H, Melnick A. SIRT3 Is a Novel Metabolic Driver of and Therapeutic Target for Chemotherapy Resistant Dlbcls Blood. 130: 643-643. DOI: 10.1182/Blood.V130.Suppl_1.643.643  0.435
2016 Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G, Rivera SA, Chramiec AG, Pronier E, Bastian L, Keller MD, ... ... Cross JR, et al. DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling. Nature Medicine. PMID 27841873 DOI: 10.1038/Nm.4210  0.33
2016 Monticelli LA, Buck MD, Flamar AL, Saenz SA, Tait Wojno ED, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald HR, Shah H, Cross JR, Diamond JM, Cantu E, Christie JD, et al. Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation. Nature Immunology. PMID 27043409 DOI: 10.1038/Ni.3421  0.37
2015 Intlekofer AM, Dematteo RG, Venneti S, Finley LW, Lu C, Judkins AR, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Thompson CB. Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metabolism. PMID 26212717 DOI: 10.1016/J.Cmet.2015.06.023  0.483
2015 Su X, Yu Y, Zhong Y, Giannopoulou EG, Hu X, Liu H, Cross JR, Rätsch G, Rice CM, Ivashkiv LB. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nature Immunology. 16: 838-49. PMID 26147685 DOI: 10.1038/Ni.3205  0.308
2015 Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, et al. Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo. Science Translational Medicine. 7: 274ra17. PMID 25673762 DOI: 10.1126/Scitranslmed.Aaa1009  0.45
2015 Pedicord VA, Cross JR, Montalvo-Ortiz W, Miller ML, Allison JP. Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness. Journal of Immunology (Baltimore, Md. : 1950). 194: 2089-98. PMID 25624453 DOI: 10.4049/Jimmunol.1402390  0.3
2015 Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature. 518: 413-6. PMID 25487152 DOI: 10.1038/Nature13981  0.527
2015 Thompson CB, Intlekofer AM, Dematteo RG, Venneti S, Finley LWS, Lu C, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Judkins AR. Abstract SY43-01: Stereochemistry matters: L-2HG as a tumor response to hypoxia Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy43-01  0.491
2015 Fuente MIdl, Young R, Rubel J, Tisnado J, Briggs S, Holodny AI, Deasy J, DeAngelis LM, Cross J, Mellinghoff IK, Thakur S. Abstract 1498: Feasibility of 2-hydroxyglutarate 1H-MR spectroscopy for routine clinical glioma imaging Cancer Research. 75: 1498-1498. DOI: 10.1158/1538-7445.Am2015-1498  0.307
2014 Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/J.Molcel.2014.08.018  0.609
2014 Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.Cd-14-0250  0.613
2014 Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, Jiang X. PTEN is a protein tyrosine phosphatase for IRS1 Nature Structural and Molecular Biology. 21: 522-527. PMID 24814346 DOI: 10.1038/Nsmb.2828  0.448
2014 Intlekofer AM, Dematteo RG, Finley LW, Cross JR, Thompson CB. Leukemia-Associated Oncometabolite 2-Hydroxyglutarate Regulates Epigenetic Modifications in Response to Oxygen Availability in Cells without IDH1/2 Mutations Blood. 124: 872-872. DOI: 10.1182/Blood.V124.21.872.872  0.504
2014 Venneti S, Dunphy M, Zhang H, Pitter K, Campos C, Carlin S, Lyashchenko S, Ploessl C, Rohle D, Omuro A, Cross J, Brennan C, Weber W, Holland E, Mellinghoff I, et al. TM-15 * GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO Neuro-Oncology. 16: v216-v216. DOI: 10.1093/Neuonc/Nou278.14  0.461
2013 Lee CH, Cross JR, Li Z, Chen Y, Neri B, Reuter VE, Motzer RJ, Russo P, Hsieh J. Global metabolic profiling of clear cell renal cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 379. PMID 28136900 DOI: 10.1200/Jco.2013.31.6_Suppl.379  0.304
2013 Piovan E, Yu J, Tosello V, Herranz D, Ambesi-Impiombato A, Da Silva AC, Sanchez-Martin M, Perez-Garcia A, Rigo I, Castillo M, Indraccolo S, Cross JR, de Stanchina E, Paietta E, Racevskis J, et al. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Cancer Cell. 24: 766-76. PMID 24291004 DOI: 10.1016/J.Ccr.2013.10.022  0.316
2013 Arpaia N, Campbell C, Fan X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR, Pfeffer K, Coffer PJ, Rudensky AY. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature. 504: 451-5. PMID 24226773 DOI: 10.1038/Nature12726  0.35
2013 Lu C, Venneti S, Akalin A, Fang F, Ward PS, Dematteo RG, Intlekofer AM, Chen C, Ye J, Hameed M, Nafa K, Agaram NP, Cross JR, Khanin R, Mason CE, et al. Induction of sarcomas by mutant IDH2. Genes & Development. 27: 1986-98. PMID 24065766 DOI: 10.1101/Gad.226753.113  0.581
2013 Chen C, Liu Y, Lu C, Cross JR, Morris JP, Shroff AS, Ward PS, Bradner JE, Thompson C, Lowe SW. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes & Development. 27: 1974-85. PMID 24065765 DOI: 10.1101/Gad.226613.113  0.514
2013 Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/Pnas.1307237110  0.587
2013 Ward PS, Lu C, Cross JR, Abdel-Wahab O, Levine RL, Schwartz GK, Thompson CB. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization. The Journal of Biological Chemistry. 288: 3804-15. PMID 23264629 DOI: 10.1074/Jbc.M112.435495  0.498
2012 Ward PS, Cross JR, Lu C, Weigert O, Abel-Wahab O, Levine RL, Weinstock DM, Sharp KA, Thompson CB. Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. Oncogene. 31: 2491-8. PMID 21996744 DOI: 10.1038/Onc.2011.416  0.48
2012 Kamphorst JJ, Cross JR, Fan J, Lu W, White E, Thompson CB, Rabinowitz JD. Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P25  0.497
2011 Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proceedings of the National Academy of Sciences of the United States of America. 108: 19611-6. PMID 22106302 DOI: 10.1073/Pnas.1117773108  0.721
2010 Vento MT, Zazzu V, Loffreda A, Cross JR, Downward J, Stoppelli MP, Iaccarino I. Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells. Plos One. 5: e15636. PMID 21203533 DOI: 10.1371/Journal.Pone.0015636  0.482
2010 Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115: 4742-9. PMID 20351312 DOI: 10.1182/Blood-2009-10-249540  0.482
2010 Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 17: 225-34. PMID 20171147 DOI: 10.1016/J.Ccr.2010.01.020  0.478
2009 Wellen KE, Hatzivassiliou G, Sachdeva UM, Bui TV, Cross JR, Thompson CB. ATP-citrate lyase links cellular metabolism to histone acetylation. Science (New York, N.Y.). 324: 1076-80. PMID 19461003 DOI: 10.1126/Science.1164097  0.481
2008 Cross JR, Postigo A, Blight K, Downward J. Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur. Cell Death and Differentiation. 15: 997-1008. PMID 18274554 DOI: 10.1038/Cdd.2008.14  0.465
2006 Postigo A, Cross JR, Downward J, Way M. Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis Cell Death and Differentiation. 13: 1651-1662. PMID 16439990 DOI: 10.1038/Sj.Cdd.4401853  0.443
2004 Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nature Neuroscience. 7: 364-72. PMID 15034583 DOI: 10.1038/Nn1210  0.589
2000 Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America. 97: 9064-9. PMID 10922060 DOI: 10.1073/Pnas.97.16.9064  0.575
Show low-probability matches.