| Year |
Citation |
Score |
| 2024 |
George A, Patil AG, Mahalakshmi R. ATP-independent assembly machinery of bacterial outer membranes: BAM complex structure and function set the stage for next-generation therapeutics. Protein Science : a Publication of the Protein Society. 33: e4896. PMID 38284489 DOI: 10.1002/pro.4896 |
0.38 |
|
| 2023 |
Bora JR, Mahalakshmi R. Empowering canonical biochemicals with cross-linked novelty: Recursions in applications of protein cross-links. Proteins. PMID 37589191 DOI: 10.1002/prot.26571 |
0.314 |
|
| 2023 |
Bora JR, Mahalakshmi R. Photoradical-mediated catalyst-independent protein cross-link with unusual fluorescence properties. Chembiochem : a European Journal of Chemical Biology. e202300380. PMID 37232210 DOI: 10.1002/cbic.202300380 |
0.344 |
|
| 2022 |
Hanif Sayyed UM, Mahalakshmi R. Mitochondrial Protein Translocation Machinery: From TOM Structural Biogenesis to Functional Regulation. The Journal of Biological Chemistry. 101870. PMID 35346689 DOI: 10.1016/j.jbc.2022.101870 |
0.386 |
|
| 2022 |
George A, Ravi R, Tiwari PB, Srivastava SR, Jain V, Mahalakshmi R. Engineering a Hyperstable Outer Membrane Protein Ail Using Thermodynamic Design. Journal of the American Chemical Society. 144: 1545-1555. PMID 35060711 DOI: 10.1021/jacs.1c05964 |
0.776 |
|
| 2021 |
Khan A, Kuriachan G, Mahalakshmi R. Cellular Interactome of Mitochondrial Voltage-Dependent Anion Channels: Oligomerization and Channel (Mis)Regulation. Acs Chemical Neuroscience. 12: 3497-3515. PMID 34503333 DOI: 10.1021/acschemneuro.1c00429 |
0.762 |
|
| 2021 |
Tiwari PB, Mahalakshmi R. Interplay of protein primary sequence, lipid membrane, and chaperone in β-barrel assembly. Protein Science : a Publication of the Protein Society. PMID 33410567 DOI: 10.1002/pro.4022 |
0.784 |
|
| 2020 |
Srivastava SR, Mahalakshmi R. Evolutionary selection of a 19-stranded mitochondrial β-barrel scaffold bears structural and functional significance. The Journal of Biological Chemistry. PMID 32817169 DOI: 10.1074/Jbc.Ra120.014366 |
0.839 |
|
| 2019 |
Gupta A, Mahalakshmi R. Single-residue physicochemical characteristics kinetically partition membrane protein self-assembly and aggregation. The Journal of Biological Chemistry. PMID 31844019 DOI: 10.1074/Jbc.Ra119.011342 |
0.76 |
|
| 2019 |
Iyer BR, Gupta S, Noordeen H, Ravi R, Pawar MD, George A, Mahalakshmi R. Molecular switch between structural compaction and thermodynamic stability by interface Xxx-Pro in transmembrane β-barrels. Biochemistry. PMID 31777252 DOI: 10.1021/Acs.Biochem.9B00731 |
0.792 |
|
| 2019 |
Gupta A, Mahalakshmi R. Reversible folding energetics of Yersinia Ail barrel reveals a hyperfluorescent intermediate. Biochimica Et Biophysica Acta. Biomembranes. 183097. PMID 31672545 DOI: 10.1016/J.Bbamem.2019.183097 |
0.78 |
|
| 2019 |
Iyer BR, Mahalakshmi R. Hydrophobic Characteristic Is Energetically Preferred for Cysteine in a Model Membrane Protein. Biophysical Journal. 117: 25-35. PMID 31221440 DOI: 10.1016/J.Bpj.2019.05.024 |
0.841 |
|
| 2019 |
Gupta A, Mahalakshmi R. Helix-strand interaction regulates stability and aggregation of the human mitochondrial membrane protein channel VDAC3. The Journal of General Physiology. PMID 30674561 DOI: 10.1085/Jgp.201812272 |
0.767 |
|
| 2019 |
Mahalakshmi R. Aromatic interactions in β-hairpin scaffold stability: A historical perspective. Archives of Biochemistry and Biophysics. 661: 39-49. PMID 30395808 DOI: 10.1016/J.Abb.2018.11.001 |
0.459 |
|
| 2018 |
Srivastava SR, Zadafiya P, Mahalakshmi R. Hydrophobic Mismatch Modulates Stability and Plasticity of Human Mitochondrial VDAC2. Biophysical Journal. PMID 30503532 DOI: 10.1016/J.Bpj.2018.11.001 |
0.846 |
|
| 2018 |
Iyer BR, Vetal PV, Noordeen H, Zadafiya P, Mahalakshmi R. Salvaging the Thermodynamic Destabilization of Interface Histidine in Transmembrane β-Barrels. Biochemistry. 57: 6669-6678. PMID 30284812 DOI: 10.1021/Acs.Biochem.8B00805 |
0.843 |
|
| 2018 |
Lella M, Mahalakshmi R. Direct Structural Annotation of Membrane Protein Aggregation Loci using Peptide-Based Reverse Mapping. Journal of Physical Chemistry Letters. 9: 2967-2971. PMID 29763546 DOI: 10.1021/Acs.Jpclett.8B00953 |
0.823 |
|
| 2018 |
Chaturvedi D, Mahalakshmi R. Folding Determinants of Transmembrane β-Barrels Using Engineered OMP Chimeras Biochemistry. 57: 1987-1996. PMID 29537829 DOI: 10.1021/Acs.Biochem.8B00012 |
0.838 |
|
| 2018 |
Chaturvedi D, Mahalakshmi R. Position—Specific contribution of interface tryptophans on membrane protein energetics Biochimica Et Biophysica Acta. 1860: 451-457. PMID 29128310 DOI: 10.1016/J.Bbamem.2017.11.003 |
0.846 |
|
| 2018 |
Mahalakshmi R. Human Mitochondrial VDAC Functionality Governs Scaffold Stability Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1353 |
0.325 |
|
| 2017 |
Maurya SR, Mahalakshmi R. Mitochondrial VDAC2 and cell homeostasis: highlighting hidden structural features and unique functionalities Biological Reviews. 92: 1843-1858. PMID 28980434 DOI: 10.1111/Brv.12311 |
0.8 |
|
| 2017 |
Chaturvedi D, Mahalakshmi R. Transmembrane β-barrels: Evolution, folding and energetics. Biochimica Et Biophysica Acta. 1859: 2467-2482. PMID 28943271 DOI: 10.1016/J.Bbamem.2017.09.020 |
0.848 |
|
| 2017 |
Mahalakshmi R, Maurya SR, Burdak B, Surti P, Patel MS, Jain V. Structural plasticity of T4 transcription co-activator gp33 revealed by a protease-resistant unfolded state. Biochemical and Biophysical Research Communications. PMID 28807826 DOI: 10.1016/J.Bbrc.2017.08.038 |
0.794 |
|
| 2017 |
Iyer BR, Zadafiya P, Vetal PV, Mahalakshmi R. Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein. The Journal of Biological Chemistry. 292: 12351-12365. PMID 28592485 DOI: 10.1074/Jbc.M117.789446 |
0.84 |
|
| 2017 |
Lella M, Mahalakshmi R. Metamorphic Proteins: Emergence of Dual Protein Folds from One Primary Sequence. Biochemistry. 56: 2971-2984. PMID 28570055 DOI: 10.1021/Acs.Biochem.7B00375 |
0.812 |
|
| 2017 |
Lella M, Mahalakshmi R. Solvation driven conformational transitions in the second transmembrane domain of mycobacteriophage holin. Biopolymers. 108. PMID 27287926 DOI: 10.1002/Bip.22894 |
0.829 |
|
| 2016 |
Maurya SR, Mahalakshmi R. Control of human VDAC-2 scaffold dynamics by interfacial tryptophans is position specific Biochimica Et Biophysica Acta. 1858: 2993-3004. PMID 27641490 DOI: 10.1016/J.Bbamem.2016.09.011 |
0.873 |
|
| 2016 |
Iyer BR, Mahalakshmi R. Distinct structural elements govern folding, stability and catalysis in the outer membrane enzyme PagP. Biochemistry. PMID 27525547 DOI: 10.1021/Acs.Biochem.6B00678 |
0.83 |
|
| 2016 |
Lella M, Mahalakshmi R. Engineering a Transmembrane Nanopore Ion Channel from a Membrane Breaker Peptide. Journal of Physical Chemistry Letters. 7: 2298-2303. PMID 27257735 DOI: 10.1021/Acs.Jpclett.6B00987 |
0.796 |
|
| 2016 |
Makwana KM, Mahalakshmi R. Capping β-hairpin with N-terminal d-amino acid stabilizes peptide scaffold. Biopolymers. 106: 260-266. PMID 26999275 DOI: 10.1002/Bip.22837 |
0.828 |
|
| 2016 |
De Pinto V, Reina S, Gupta A, Messina A, Mahalakshmi R. Role of cysteines in mammalian VDAC isoforms' function. Biochimica Et Biophysica Acta. PMID 26947058 DOI: 10.1016/J.Bbabio.2016.02.020 |
0.722 |
|
| 2016 |
Makwana KM, Mahalakshmi R. Stereopositional Outcome in the Packing of Dissimilar Aromatics in Designed β‐Hairpins Chemistry: a European Journal. 22: 4147-4156. PMID 26864542 DOI: 10.1002/Chem.201504428 |
0.835 |
|
| 2016 |
Reina S, Checchetto V, Saletti R, Gupta A, Chaturvedi D, Guardiani C, Guarino F, Scorciapino MA, Magrì A, Foti S, Ceccarelli M, Messina AA, Mahalakshmi R, Szabo I, De Pinto V. VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications. Oncotarget. PMID 26760765 DOI: 10.18632/Oncotarget.6850 |
0.813 |
|
| 2016 |
Maurya SR, Mahalakshmi R. VDAC-2: Mitochondrial outer membrane regulator masquerading as a channel? The Febs Journal. 283: 1831-6. PMID 26709731 DOI: 10.1111/Febs.13637 |
0.807 |
|
| 2016 |
Lella M, Kamilla S, Jain V, Mahalakshmi R. Molecular Mechanism of Holin Transmembrane Domain I in Pore Formation and Bacterial Cell Death. Acs Chemical Biology. PMID 26701742 DOI: 10.1021/Acschembio.5B00875 |
0.813 |
|
| 2015 |
Maurya SR, Mahalakshmi R. N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry. The Journal of Biological Chemistry. 290: 30240-52. PMID 26487717 DOI: 10.1074/Jbc.M115.693978 |
0.814 |
|
| 2015 |
Makwana KM, Mahalakshmi R. Implications of aromatic–aromatic interactions: From protein structures to peptide models Protein Science. 24: 1920-1933. PMID 26402741 DOI: 10.1002/Pro.2814 |
0.523 |
|
| 2015 |
Iyer BR, Mahalakshmi R. Residue-Dependent Thermodynamic Cost and Barrel Plasticity Balances Activity in the PhoPQ-Activated Enzyme PagP of Salmonella typhimurium. Biochemistry. 54: 5712-22. PMID 26334694 DOI: 10.1021/Acs.Biochem.5B00543 |
0.819 |
|
| 2015 |
Makwana KM, Mahalakshmi R. Trp-Trp Cross-Linking: A Structure–Reactivity Relationship in the Formation and Design of Hyperstable Peptide β-Hairpin and α-Helix Scaffolds Organic Letters. 17: 2498-2501. PMID 25938256 DOI: 10.1021/Acs.Orglett.5B01017 |
0.809 |
|
| 2015 |
Makwana KM, Mahalakshmi R. NMR Analysis of Tuning Cross-Strand Phe/Tyr/Trp-Trp Interactions in Designed β-Hairpin Peptides: Terminal Switch from L to D Amino Acid as a Strategy for β-Hairpin Capping. The Journal of Physical Chemistry. B. 119: 5376-85. PMID 25849307 DOI: 10.1021/Acs.Jpcb.5B00554 |
0.843 |
|
| 2015 |
Makwana KM, Mahalakshmi R. Nature of aryl-tyrosine interactions contribute to β-hairpin scaffold stability: NMR evidence for alternate ring geometry. Physical Chemistry Chemical Physics. 17: 4220-4230. PMID 25569770 DOI: 10.1039/C4Cp04991H |
0.834 |
|
| 2015 |
Gupta A, Iyer BR, Chaturvedi D, Maurya SR, Mahalakshmi R. Thermodynamic, structural and functional properties of membrane protein inclusion bodies are analogous to purified counterparts: Case study from bacteria and humans Rsc Advances. 5: 1227-1234. DOI: 10.1039/C4Ra11207E |
0.492 |
|
| 2014 |
Chaturvedi D, Mahalakshmi R. Juxtamembrane tryptophans have distinct roles in defining the OmpX barrel-micelle boundary and facilitating protein-micelle association. Febs Letters. 588: 4464-71. PMID 25448987 DOI: 10.1016/J.Febslet.2014.10.017 |
0.858 |
|
| 2014 |
Gupta A, Zadafiya P, Mahalakshmi R. Differential contribution of tryptophans to the folding and stability of the attachment invasion locus transmembrane β-barrel from Yersinia pestis. Scientific Reports. 4: 6508. PMID 25266561 DOI: 10.1038/Srep06508 |
0.783 |
|
| 2014 |
Makwana KM, Mahalakshmi R. Asymmetric contribution of aromatic interactions stems from spatial positioning of the interacting aryl pairs in β-hairpins. Chembiochem. 15: 2357-2360. PMID 25196944 DOI: 10.1002/Cbic.201402340 |
0.821 |
|
| 2014 |
Maurya SR, Mahalakshmi R. Cysteine residues impact the stability and micelle interaction dynamics of the human mitochondrial β-barrel anion channel hVDAC-2. Plos One. 9: e92183. PMID 24642864 DOI: 10.1371/Journal.Pone.0092183 |
0.848 |
|
| 2014 |
Maurya SR, Mahalakshmi R. Influence of protein-micelle ratios and cysteine residues on the kinetic stability and unfolding rates of human mitochondrial VDAC-2. Plos One. 9: e87701. PMID 24494036 DOI: 10.1371/Journal.Pone.0087701 |
0.859 |
|
| 2014 |
Makwana KM, Mahalakshmi R. Comparative analysis of cross strand aromatic-Phe interactions in designed peptide β-hairpins. Organic and Biomolecular Chemistry. 12: 2053-2061. PMID 24413913 DOI: 10.1039/C3Ob42247J |
0.83 |
|
| 2014 |
Ravikiran B, Mahalakshmi R. Unusual post-translational protein modifications: the benefits of sophistication Rsc Advances. 4: 33958-33974. DOI: 10.1039/C4Ra04694C |
0.39 |
|
| 2013 |
Chaturvedi D, Mahalakshmi R. Methionine mutations of outer membrane protein X influence structural stability and beta-barrel unfolding. Plos One. 8: e79351. PMID 24265768 DOI: 10.1371/Journal.Pone.0079351 |
0.853 |
|
| 2013 |
Lella M, Mahalakshmi R. Pro-Gly mediated conformational switch of mycobacteriophage D29 holin transmembrane domain I is lipid concentration driven. Chemical Communications. 49: 9594-9596. PMID 24018990 DOI: 10.1039/C3Cc45058A |
0.814 |
|
| 2013 |
Makwana KM, Raghothama S, Mahalakshmi R. Stabilizing effect of electrostatic vs. aromatic interactions in diproline nucleated peptide β-hairpins Physical Chemistry Chemical Physics. 15: 15321-15324. PMID 23942893 DOI: 10.1039/C3Cp52770K |
0.822 |
|
| 2013 |
Maurya SR, Mahalakshmi R. Modulation of human mitochondrial voltage-dependent anion channel 2 (hVDAC-2) structural stability by cysteine-assisted barrel-lipid interactions. The Journal of Biological Chemistry. 288: 25584-92. PMID 23873934 DOI: 10.1074/Jbc.M113.493692 |
0.85 |
|
| 2013 |
Maurya SR, Chaturvedi D, Mahalakshmi R. Modulating lipid dynamics and membrane fluidity to drive rapid folding of a transmembrane barrel. Scientific Reports. 3: 1989. PMID 23771099 DOI: 10.1038/Srep01989 |
0.794 |
|
| 2012 |
Gupta A, Chaturvedi D, Mahalakshmi R. Modified CNBr Cleavage Protocol for Efficient Separation of Met-Ser Containing OmpX-Om14 Membrane Protein Fusion International Review of Biophysical Chemistry. 3: 147-156. DOI: 10.15866/Irebic.V3I5.1572 |
0.443 |
|
| 2011 |
Plesniak LA, Mahalakshmi R, Rypien C, Yang Y, Racic J, Marassi FM. Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipids. Biochimica Et Biophysica Acta. 1808: 482-489. PMID 20883662 DOI: 10.1016/J.Bbamem.2010.09.017 |
0.462 |
|
| 2009 |
Petrovic AG, Polavarapu PL, Mahalakshmi R, Balaram P. Characterization of folded conformations in a tetrapeptide containing two tryptophan residues by vibrational circular dichroism. Chirality. 21: E76-85. PMID 19750497 DOI: 10.1002/Chir.20779 |
0.494 |
|
| 2008 |
Mahalakshmi R, Marassi FM. Orientation of the Escherichia coli Outer Membrane Protein OmpX in Phospholipid Bilayer Membranes Determined by Solid-State NMR Biochemistry. 47: 6531-6538. PMID 18512961 DOI: 10.1021/Bi800362B |
0.514 |
|
| 2008 |
Sengupta A, Mahalakshmi R, Shamala N, Balaram P. Aromatic interactions in tryptophan-containing peptides: crystal structures of model tryptophan peptides and phenylalanine analogs. Journal of Peptide Research. 65: 113-129. PMID 15686542 DOI: 10.1111/J.1399-3011.2004.00191.X |
0.539 |
|
| 2007 |
Mahalakshmi R, Franzin CM, Choi J, Marassi FM. NMR structural studies of the bacterial outer membrane protein OmpX in oriented lipid bilayer membranes. Biochimica Et Biophysica Acta. 1768: 3216-24. PMID 17916325 DOI: 10.1016/J.Bbamem.2007.08.008 |
0.453 |
|
| 2007 |
Mahalakshmi R, Sengupta A, Raghothama S, Shamala N, Balaram P. Tryptophan rich peptides: influence of indole rings on backbone conformation. Biopolymers. 88: 36-54. PMID 17091496 DOI: 10.1002/Bip.20625 |
0.765 |
|
| 2006 |
Mahalakshmi R, Balaram P. Non-protein amino acids in the design of secondary structure scaffolds. Methods in Molecular Biology (Clifton, N.J.). 340: 71-94. PMID 16957333 DOI: 10.1385/1-59745-116-9:71 |
0.558 |
|
| 2006 |
Mahalakshmi R, Raghothama S, Balaram P. NMR analysis of aromatic interactions in designed peptide β-hairpins Journal of the American Chemical Society. 128: 1125-1138. PMID 16433528 DOI: 10.1021/Ja054040K |
0.756 |
|
| 2005 |
Mahalakshmi R, Shanmugam G, Polavarapu PL, Balaram P. Circular dichroism of designed peptide helices and beta-hairpins: analysis of Trp- and Tyr-rich peptides. Chembiochem : a European Journal of Chemical Biology. 6: 2152-8. PMID 16261550 DOI: 10.1002/Cbic.200500152 |
0.577 |
|
| 2005 |
Mahalakshmi R, Sengupta A, Raghothama S, Shamala N, Balaram P. Tryptophan-containing peptide helices: interactions involving the indole side chain. The Journal of Peptide Research : Official Journal of the American Peptide Society. 66: 277-96. PMID 16218995 DOI: 10.1111/J.1399-3011.2005.00301.X |
0.575 |
|
| 2004 |
Padmashri R, Chakrabarti KS, Sahal D, Mahalakshmi R, Sarma SP, Sikdar SK. Functional characterization of the pentapeptide QYNAD on rNav1.2 channels and its NMR structure. PflüGers Archiv: European Journal of Physiology. 447: 895-907. PMID 14691725 DOI: 10.1007/S00424-003-1194-9 |
0.354 |
|
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