Matthew James Smith - Publications

Affiliations: 
2015- IRIC, Université de Montréal 
Area:
RAS GTPases

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Smith MJ. Defining bone fide effectors of RAS GTPases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300088. PMID 37401638 DOI: 10.1002/bies.202300088  0.364
2022 Goudreault M, Gagné V, Jo CH, Singh S, Killoran RC, Gingras AC, Smith MJ. Afadin couples RAS GTPases to the polarity rheostat Scribble. Nature Communications. 13: 4562. PMID 35931706 DOI: 10.1038/s41467-022-32335-8  0.312
2022 Bernal Astrain G, Nikolova M, Smith MJ. Functional diversity in the RAS subfamily of small GTPases. Biochemical Society Transactions. PMID 35356965 DOI: 10.1042/BST20211166  0.317
2021 Killoran RC, Smith MJ. NMR Detection Methods for Profiling RAS Nucleotide Cycling. Methods in Molecular Biology (Clifton, N.J.). 2262: 169-182. PMID 33977476 DOI: 10.1007/978-1-0716-1190-6_9  0.378
2020 Singh S, Smith MJ. RAS GTPase signalling to alternative effector pathways. Biochemical Society Transactions. 48: 2241-2252. PMID 33125484 DOI: 10.1042/BST20200506  0.325
2020 Dhanaraman T, Singh S, Killoran RC, Singh A, Xu X, Shifman JM, Smith MJ. RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway. Science Signaling. 13. PMID 33051258 DOI: 10.1126/scisignal.abb4778  0.346
2020 Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Correction to: Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants. Molecular Diagnosis & Therapy. PMID 32572786 DOI: 10.1007/s40291-020-00479-2  0.301
2020 Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants. Molecular Diagnosis & Therapy. PMID 32306292 DOI: 10.1007/s40291-020-00462-x  0.311
2019 Killoran RC, Smith MJ. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel. The Journal of Biological Chemistry. PMID 31088913 DOI: 10.1074/jbc.RA119.008653  0.376
2016 Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology. PMID 27820802 DOI: 10.1038/Nchembio.2231  0.311
2016 Fang Z, Marshall CB, Yin JC, Mazhab-Jafari MT, Gasmi-Seabrook GM, Smith MJ, Nishikawa T, Xu Y, Neel BG, Ikura M. Biochemical Classification of Disease-Associated Mutants of RAS-Like Protein Expressed in Many Tissues (RIT1). The Journal of Biological Chemistry. PMID 27226556 DOI: 10.1074/jbc.M116.714196  0.666
2015 Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proceedings of the National Academy of Sciences of the United States of America. 112: 6625-30. PMID 25941399 DOI: 10.1073/Pnas.1419895112  0.655
2014 Smith MJ, Ikura M. Integrated RAS signaling defined by parallel NMR detection of effectors and regulators. Nature Chemical Biology. 10: 223-30. PMID 24441586 DOI: 10.1038/nchembio.1435  0.347
2013 Long D, Marshall CB, Bouvignies G, Mazhab-Jafari MT, Smith MJ, Ikura M, Kay LE. A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues. Angewandte Chemie (International Ed. in English). 52: 10771-4. PMID 24039022 DOI: 10.1002/Anie.201305434  0.658
2013 Smith MJ, Neel BG, Ikura M. NMR-based functional profiling of RASopathies and oncogenic RAS mutations. Proceedings of the National Academy of Sciences of the United States of America. 110: 4574-9. PMID 23487764 DOI: 10.1073/pnas.1218173110  0.369
2012 Marshall CB, Meiri D, Smith MJ, Mazhab-Jafari MT, Gasmi-Seabrook GM, Rottapel R, Stambolic V, Ikura M. Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts. Methods (San Diego, Calif.). 57: 473-85. PMID 22750304 DOI: 10.1016/J.Ymeth.2012.06.014  0.655
2010 Mazhab-Jafari MT, Marshall CB, Smith M, Gasmi-Seabrook GM, Stambolic V, Rottapel R, Neel BG, Ikura M. Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. The Journal of Biological Chemistry. 285: 5132-6. PMID 20018863 DOI: 10.1074/Jbc.C109.064766  0.666
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