Year |
Citation |
Score |
2023 |
Smith MJ. Defining bone fide effectors of RAS GTPases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300088. PMID 37401638 DOI: 10.1002/bies.202300088 |
0.364 |
|
2022 |
Goudreault M, Gagné V, Jo CH, Singh S, Killoran RC, Gingras AC, Smith MJ. Afadin couples RAS GTPases to the polarity rheostat Scribble. Nature Communications. 13: 4562. PMID 35931706 DOI: 10.1038/s41467-022-32335-8 |
0.312 |
|
2022 |
Bernal Astrain G, Nikolova M, Smith MJ. Functional diversity in the RAS subfamily of small GTPases. Biochemical Society Transactions. PMID 35356965 DOI: 10.1042/BST20211166 |
0.317 |
|
2021 |
Killoran RC, Smith MJ. NMR Detection Methods for Profiling RAS Nucleotide Cycling. Methods in Molecular Biology (Clifton, N.J.). 2262: 169-182. PMID 33977476 DOI: 10.1007/978-1-0716-1190-6_9 |
0.378 |
|
2020 |
Singh S, Smith MJ. RAS GTPase signalling to alternative effector pathways. Biochemical Society Transactions. 48: 2241-2252. PMID 33125484 DOI: 10.1042/BST20200506 |
0.325 |
|
2020 |
Dhanaraman T, Singh S, Killoran RC, Singh A, Xu X, Shifman JM, Smith MJ. RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway. Science Signaling. 13. PMID 33051258 DOI: 10.1126/scisignal.abb4778 |
0.346 |
|
2020 |
Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Correction to: Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants. Molecular Diagnosis & Therapy. PMID 32572786 DOI: 10.1007/s40291-020-00479-2 |
0.301 |
|
2020 |
Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants. Molecular Diagnosis & Therapy. PMID 32306292 DOI: 10.1007/s40291-020-00462-x |
0.311 |
|
2019 |
Killoran RC, Smith MJ. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel. The Journal of Biological Chemistry. PMID 31088913 DOI: 10.1074/jbc.RA119.008653 |
0.376 |
|
2016 |
Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology. PMID 27820802 DOI: 10.1038/Nchembio.2231 |
0.311 |
|
2016 |
Fang Z, Marshall CB, Yin JC, Mazhab-Jafari MT, Gasmi-Seabrook GM, Smith MJ, Nishikawa T, Xu Y, Neel BG, Ikura M. Biochemical Classification of Disease-Associated Mutants of RAS-Like Protein Expressed in Many Tissues (RIT1). The Journal of Biological Chemistry. PMID 27226556 DOI: 10.1074/jbc.M116.714196 |
0.666 |
|
2015 |
Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proceedings of the National Academy of Sciences of the United States of America. 112: 6625-30. PMID 25941399 DOI: 10.1073/Pnas.1419895112 |
0.655 |
|
2014 |
Smith MJ, Ikura M. Integrated RAS signaling defined by parallel NMR detection of effectors and regulators. Nature Chemical Biology. 10: 223-30. PMID 24441586 DOI: 10.1038/nchembio.1435 |
0.347 |
|
2013 |
Long D, Marshall CB, Bouvignies G, Mazhab-Jafari MT, Smith MJ, Ikura M, Kay LE. A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues. Angewandte Chemie (International Ed. in English). 52: 10771-4. PMID 24039022 DOI: 10.1002/Anie.201305434 |
0.658 |
|
2013 |
Smith MJ, Neel BG, Ikura M. NMR-based functional profiling of RASopathies and oncogenic RAS mutations. Proceedings of the National Academy of Sciences of the United States of America. 110: 4574-9. PMID 23487764 DOI: 10.1073/pnas.1218173110 |
0.369 |
|
2012 |
Marshall CB, Meiri D, Smith MJ, Mazhab-Jafari MT, Gasmi-Seabrook GM, Rottapel R, Stambolic V, Ikura M. Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts. Methods (San Diego, Calif.). 57: 473-85. PMID 22750304 DOI: 10.1016/J.Ymeth.2012.06.014 |
0.655 |
|
2010 |
Mazhab-Jafari MT, Marshall CB, Smith M, Gasmi-Seabrook GM, Stambolic V, Rottapel R, Neel BG, Ikura M. Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. The Journal of Biological Chemistry. 285: 5132-6. PMID 20018863 DOI: 10.1074/Jbc.C109.064766 |
0.666 |
|
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