| Year |
Citation |
Score |
| 2023 |
Dym O, Aggarwal N, Ashani Y, Leader H, Albeck S, Unger T, Hamer-Rogotner S, Silman I, Tawfik DS, Sussman JL. The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallographica. Section D, Structural Biology. 79: 992-1009. PMID 37860961 DOI: 10.1107/S2059798323007672 |
0.532 |
|
| 2023 |
Pokorna S, Khersonsky O, Lipsh-Sokolik R, Goldenzweig A, Nielsen R, Ashani Y, Peleg Y, Unger T, Albeck S, Dym O, Tirosh A, Tarayra R, Hocquemiller M, Laufer R, Ben-Dor S, et al. Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification. The Febs Journal. PMID 36808692 DOI: 10.1111/febs.16758 |
0.428 |
|
| 2021 |
Peleg Y, Vincentelli R, Collins BM, Chen KE, Livingstone EK, Weeratunga S, Leneva N, Guo Q, Remans K, Perez K, E K Bjerga G, Larsen Ø, Vaněk O, Skořepa O, Jacquemin S, ... ... Dym O, et al. Community-wide experimental evaluation of the PROSS stability-design method. Journal of Molecular Biology. 166964. PMID 33781758 DOI: 10.1016/j.jmb.2021.166964 |
0.306 |
|
| 2021 |
Daniel E, Maksimainen MM, Smith N, Ratas V, Biterova E, Murthy SN, Rahman MT, Kiema TR, Sridhar S, Cordara G, Dalwani S, Venkatesan R, Prilusky J, Dym O, Lehtiö L, et al. IceBear: an intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition. Acta Crystallographica. Section D, Structural Biology. 77: 151-163. PMID 33559605 DOI: 10.1107/S2059798320015223 |
0.482 |
|
| 2019 |
Ben-David M, Soskine M, Dubovetskyi A, Cherukuri KP, Dym O, Sussman JL, Liao Q, Szeler K, Kamerlin SCL, Tawfik DS. Enzyme neo- versus re-functionalization - an epistatic ratchet versus a smooth reversible transition. Molecular Biology and Evolution. PMID 31873734 DOI: 10.1093/Molbev/Msz298 |
0.448 |
|
| 2019 |
Novichkova DA, Lushchekina SV, Dym O, Masson P, Silman I, Sussman JL. The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability. Chemico-Biological Interactions. PMID 31202688 DOI: 10.1016/J.Cbi.2019.06.012 |
0.455 |
|
| 2018 |
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, et al. Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Molecular Cell. 70: 380. PMID 29677494 DOI: 10.1016/j.molcel.2018.03.035 |
0.491 |
|
| 2016 |
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, et al. Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Molecular Cell. PMID 27425410 DOI: 10.1016/J.Molcel.2016.06.012 |
0.531 |
|
| 2016 |
Dym O, Song W, Felder C, Roth E, Shnyrov V, Ashani Y, Xu Y, Joosten RP, Weiner L, Sussman JL, Silman I. The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue/Acetylcholinesterase Complex. Protein Science : a Publication of the Protein Society. PMID 26990888 DOI: 10.1002/Pro.2923 |
0.525 |
|
| 2012 |
Xu Y, Li MJ, Greenblatt H, Chen W, Paz A, Dym O, Peleg Y, Chen T, Shen X, He J, Jiang H, Silman I, Sussman JL. Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. Acta Crystallographica. Section D, Biological Crystallography. 68: 13-25. PMID 22194329 DOI: 10.1107/S0907444911047251 |
0.521 |
|
| 2011 |
Li MJ, Greenblatt HM, Dym O, Albeck S, Pais A, Gunanathan C, Milstein D, Degani H, Sussman JL. Structure of estradiol metal chelate and estrogen receptor complex: the basis for designing a new class of selective estrogen receptor modulators. Journal of Medicinal Chemistry. 54: 3575-80. PMID 21473635 DOI: 10.1021/Jm200192Y |
0.418 |
|
| 2011 |
Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. A de novo protein binding pair by computational design and directed evolution. Molecular Cell. 42: 250-60. PMID 21458342 DOI: 10.1016/J.Molcel.2011.03.010 |
0.312 |
|
| 2010 |
Yadid I, Kirshenbaum N, Sharon M, Dym O, Tawfik DS. Metamorphic proteins mediate evolutionary transitions of structure. Proceedings of the National Academy of Sciences of the United States of America. 107: 7287-92. PMID 20368465 DOI: 10.1073/Pnas.0912616107 |
0.304 |
|
| 2008 |
Cohen S, Dym O, Albeck S, Ben-Dov E, Cahan R, Firer M, Zaritsky A. High-resolution crystal structure of activated Cyt2Ba monomer from Bacillus thuringiensis subsp. israelensis. Journal of Molecular Biology. 380: 820-7. PMID 18571667 DOI: 10.1016/j.jmb.2008.05.010 |
0.357 |
|
| 2008 |
Meged R, Dym O, Sussman JL. High throughput pH optimization of protein crystallization. Methods in Molecular Biology (Clifton, N.J.). 426: 411-418. PMID 18542880 DOI: 10.1007/978-1-60327-058-8_27 |
0.482 |
|
| 2008 |
Manicka S, Peleg Y, Unger T, Albeck S, Dym O, Greenblatt HM, Bourenkov G, Lamzin V, Krishnaswamy S, Sussman JL. Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12. Proteins. 71: 2102-8. PMID 18361457 DOI: 10.1002/Prot.22023 |
0.513 |
|
| 2008 |
Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Dym O, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202 |
0.444 |
|
| 2007 |
Shaaltiel Y, Bartfeld D, Hashmueli S, Baum G, Brill-Almon E, Galili G, Dym O, Boldin-Adamsky SA, Silman I, Sussman JL, Futerman AH, Aviezer D. Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system. Plant Biotechnology Journal. 5: 579-90. PMID 17524049 DOI: 10.1111/J.1467-7652.2007.00263.X |
0.454 |
|
| 2005 |
Albeck S, Burstein Y, Dym O, Jacobovitch Y, Levi N, Meged R, Michael Y, Peleg Y, Prilusky J, Schreiber G, Silman I, Unger T, Sussman JL. Three-dimensional structure determination of proteins related to human health in their functional context at the Israel Structural Proteomics Center (ISPC) Acta Crystallographica Section D: Biological Crystallography. 61: 1364-1372. PMID 16204888 DOI: 10.1107/S0907444905023565 |
0.535 |
|
| 2003 |
Wang W, Dgany O, Dym O, Altman A, Shoseyov O, Almog O. Crystallization and preliminary X-ray crystallographic analysis of SP1, a novel chaperone-like protein. Acta Crystallographica. Section D, Biological Crystallography. 59: 512-4. PMID 12595711 |
0.3 |
|
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