Thomas Conrad

2010 Chemistry University of California, San Diego, La Jolla, CA 
"Thomas Conrad"


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Alexander Hoffmann grad student 2010 UCSD (Chemistry Tree)
 (The Genetic Basis for Adaptation of Escherichia coli to Growth in Minimal Media.)
Bernhard O. Palsson grad student 2010 UCSD
 (The Genetic Basis for Adaptation of Escherichia coli to Growth in Minimal Media.)
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Yong HT, Yamamoto N, Takeuchi R, et al. (2013) Development of a system for discovery of genetic interactions for essential genes in Escherichia coli K-12. Genes & Genetic Systems. 88: 233-40
Orth JD, Conrad TM, Na J, et al. (2011) A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011. Molecular Systems Biology. 7: 535
Conrad TM, Lewis NE, Palsson BØ. (2011) Microbial laboratory evolution in the era of genome-scale science. Molecular Systems Biology. 7: 509
Applebee MK, Joyce AR, Conrad TM, et al. (2011) Functional and metabolic effects of adaptive glycerol kinase (GLPK) mutants in Escherichia coli. The Journal of Biological Chemistry. 286: 23150-9
Nam H, Conrad TM, Lewis NE. (2011) The role of cellular objectives and selective pressures in metabolic pathway evolution. Current Opinion in Biotechnology. 22: 595-600
Charusanti P, Conrad TM, Knight EM, et al. (2010) Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene. Plos Genetics. 6: e1001186
Conrad TM, Frazier M, Joyce AR, et al. (2010) RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media. Proceedings of the National Academy of Sciences of the United States of America. 107: 20500-5
Lewis NE, Hixson KK, Conrad TM, et al. (2010) Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models. Molecular Systems Biology. 6: 390
Schellenberger J, Park JO, Conrad TM, et al. (2010) BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions. Bmc Bioinformatics. 11: 213
Conrad TM, Joyce AR, Applebee MK, et al. (2009) Whole-genome resequencing of Escherichia coli K-12 MG1655 undergoing short-term laboratory evolution in lactate minimal media reveals flexible selection of adaptive mutations. Genome Biology. 10: R118
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