Samuel C. Flores, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Computational Biology and Bioinformatics
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"Samuel Flores"

Parents

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Mark B. Gerstein grad student 2008 Yale
 (Flexibility and domain dynamics of proteins.)
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Publications

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Flores SC, Alexiou A, Glaros A. (2021) Mining the Protein Data Bank to improve prediction of changes in protein-protein binding. Plos One. 16: e0257614
Nosrati M, Solbak S, Nordesjö O, et al. (2017) Insights from engineering the Affibody-Fc interaction with a computational-experimental method. Protein Engineering, Design & Selection : Peds. 1-9
Cheng RR, Nordesjö O, Hayes RL, et al. (2016) Connecting the sequence-space of bacterial signaling proteins to phenotypes using coevolutionary landscapes. Molecular Biology and Evolution
Dourado DF, Flores SC. (2016) Modeling and fitting protein-protein complexes to predict change of binding energy. Scientific Reports. 6: 25406
Tek A, Korostelev AA, Flores SC. (2015) MMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory. Nucleic Acids Research
Fiesel FC, Caulfield TR, Moussaud-Lamodière EL, et al. (2015) Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin. Human Mutation. 36: 774-86
Caulfield TR, Fiesel FC, Moussaud-Lamodière EL, et al. (2014) Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin. Plos Computational Biology. 10: e1003935
Dourado DF, Flores SC. (2014) A multiscale approach to predicting affinity changes in protein-protein interfaces. Proteins. 82: 2681-90
Flores SC. (2014) Fast fitting to low resolution density maps: elucidating large-scale motions of the ribosome. Nucleic Acids Research. 42: e9
Flores SC. (2014) Elucidating Ribosomal Translocation with Internal Coordinate Flexible Fitting Biophysical Journal. 106
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