William H. Sheffler, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
protein structure prediction
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"William Sheffler"

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David Baker grad student 2009 University of Washington
 (A volumetric score function for computational protein structure modeling and protein structure validation.)
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Publications

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Li Z, Wang S, Nattermann U, et al. (2023) Accurate computational design of three-dimensional protein crystals. Nature Materials
Watson JL, Juergens D, Bennett NR, et al. (2023) De novo design of protein structure and function with RFdiffusion. Nature
Sheffler W, Yang EC, Dowling Q, et al. (2023) Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock. Plos Computational Biology. 19: e1010680
Wu K, Bai H, Chang YT, et al. (2023) De novo design of modular peptide-binding proteins by superhelical matching. Nature
Wang JYJ, Khmelinskaia A, Sheffler W, et al. (2023) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America. 120: e2214556120
Said MY, Kang CS, Wang S, et al. (2022) Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks. Chemistry of Materials : a Publication of the American Chemical Society. 34: 9736-9744
Hsia Y, Mout R, Sheffler W, et al. (2021) Design of multi-scale protein complexes by hierarchical building block fusion. Nature Communications. 12: 2294
Divine R, Dang HV, Ueda G, et al. (2021) Designed proteins assemble antibodies into modular nanocages. Science (New York, N.Y.). 372
Ben-Sasson AJ, Watson JL, Sheffler W, et al. (2021) Author Correction: Design of biologically active binary protein 2D materials. Nature
Ben-Sasson AJ, Watson JL, Sheffler W, et al. (2021) Design of biologically active binary protein 2D materials. Nature
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