Patrick Weinkam, Ph.D.
Affiliations: | Chemistry | University of California, San Diego, La Jolla, CA |
Area:
protein folding, regulatory networks, glasses, many-body phenomenaGoogle:
"Patrick Weinkam"Parents
Sign in to add mentor| Peter G. Wolynes | grad student | 2009 | UCSD | |
| (The folding energy landscape of cytochrome c: Theoretical and experimental investigations.) | ||||
| Floyd E. Romesberg | grad student | 2004-2009 | Scripps Institute (Chemistry Tree) | |
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Publications
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| Cimermancic P, Weinkam P, Rettenmaier TJ, et al. (2016) CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites. Journal of Molecular Biology |
| Pieper U, Webb BM, Dong GQ, et al. (2014) ModBase, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Research. 42: D336-46 |
| Weinkam P, Sali A. (2013) Mapping polymerization and allostery of hemoglobin S using point mutations. The Journal of Physical Chemistry. B. 117: 13058-68 |
| Guttman M, Weinkam P, Sali A, et al. (2013) All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins. Structure (London, England : 1993). 21: 321-31 |
| Weinkam P, Chen YC, Pons J, et al. (2013) Impact of mutations on the allosteric conformational equilibrium. Journal of Molecular Biology. 425: 647-61 |
| Weinkam P, Pons J, Sali A. (2012) Structure-based model of allostery predicts coupling between distant sites. Proceedings of the National Academy of Sciences of the United States of America. 109: 4875-80 |
| Craig PO, Lätzer J, Weinkam P, et al. (2011) Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes. Journal of the American Chemical Society. 133: 17463-72 |
| Weinkam P, Zimmermann J, Romesberg FE, et al. (2010) The folding energy landscape and free energy excitations of cytochrome c. Accounts of Chemical Research. 43: 652-60 |
| Weinkam P, Romesberg FE, Wolynes PG. (2009) Chemical frustration in the protein folding landscape: grand canonical ensemble simulations of cytochrome c. Biochemistry. 48: 2394-402 |
| Weinkam P, Pletneva EV, Gray HB, et al. (2009) Electrostatic effects on funneled landscapes and structural diversity in denatured protein ensembles. Proceedings of the National Academy of Sciences of the United States of America. 106: 1796-801 |