Patrick Weinkam, Ph.D.

Affiliations: 
Chemistry University of California, San Diego, La Jolla, CA 
Area:
protein folding, regulatory networks, glasses, many-body phenomena
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"Patrick Weinkam"

Parents

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Peter G. Wolynes grad student 2009 UCSD
 (The folding energy landscape of cytochrome c: Theoretical and experimental investigations.)
Floyd E. Romesberg grad student 2004-2009 Scripps Institute (Chemistry Tree)
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Publications

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Pieper U, Webb BM, Dong GQ, et al. (2014) ModBase, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Research. 42: D336-46
Weinkam P, Chen YC, Pons J, et al. (2013) Impact of mutations on the allosteric conformational equilibrium. Journal of Molecular Biology. 425: 647-61
Weinkam P, Pons J, Sali A. (2012) Structure-based model of allostery predicts coupling between distant sites. Proceedings of the National Academy of Sciences of the United States of America. 109: 4875-80
Craig PO, Hoffman RM, Lätzer J, et al. (2012) Analysis of Native H/D Exchange Dynamics in EX1/EX2 Conditions using Structure Based Model Simulations Biophysical Journal. 102: 448a
Craig PO, Lätzer J, Weinkam P, et al. (2011) Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes. Journal of the American Chemical Society. 133: 17463-72
Weinkam P, Zimmermann J, Romesberg FE, et al. (2010) The folding energy landscape and free energy excitations of cytochrome c. Accounts of Chemical Research. 43: 652-60
Craig PO, Lätzer J, Weinkam P, et al. (2010) Prediction of H Exchange from Perfectly Funneled Structure Based Models Biophysical Journal. 98: 638a
Weinkam P, Romesberg FE, Wolynes PG. (2009) Chemical frustration in the protein folding landscape: grand canonical ensemble simulations of cytochrome c. Biochemistry. 48: 2394-402
Weinkam P, Pletneva EV, Gray HB, et al. (2009) Electrostatic effects on funneled landscapes and structural diversity in denatured protein ensembles. Proceedings of the National Academy of Sciences of the United States of America. 106: 1796-801
Hegler JA, Weinkam P, Wolynes PG. (2008) The spectrum of biomolecular states and motions. Hfsp Journal. 2: 307-13
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