Adam Frankel, Ph.D.

Affiliations: 
2001 University of California, Los Angeles, Los Angeles, CA 
Area:
macromolecular repair for DNA and proteins
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"Adam Frankel"

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Steven G. Clarke grad student 2001 UCLA
 (The emerging family of eukaryotic protein arginine N-methyltransferases.)
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Publications

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Hendrickson-Rebizant T, Sudhakar SRN, Rowley MJ, et al. (2024) Structure, Function, and Activity of Small Molecule and Peptide Inhibitors of Protein Arginine Methyltransferase 1. Journal of Medicinal Chemistry
Rowley MJ, Prout-Holm RA, Liu RW, et al. (2023) Protein arginine N-methyltransferase 2 (PRMT2) plays a noncatalytic role in the histone methylation activity of PRMT1. The Journal of Biological Chemistry. 105360
Rowley MJ, Taylor SA, Frankel A. (2022) Protein arginine N-methyltransferase activity determination with filter binding and phosphor screening (FBAPS) assay. Analytical Biochemistry. 653: 114778
Frankel A. (2020) Biological and chemical approaches to understanding protein arginine methylation. Methods (San Diego, Calif.)
Silva ACE, Wu CY, Citadin CT, et al. (2019) Protein Arginine Methyltransferases in Cardiovascular and Neuronal Function. Molecular Neurobiology
Brown JI, Page BDG, Frankel A. (2019) The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1. Methods (San Diego, Calif.)
Frankel A, Brown JI. (2018) Evaluation of kinetic data: What the numbers tell us about PRMTs. Biochimica Et Biophysica Acta. Proteins and Proteomics
Brown JI, Koopmans T, van Strien J, et al. (2017) Kinetic analysis of PRMT1 reveals multifactorial processivity and a sequential ordered mechanism. Chembiochem : a European Journal of Chemical Biology
Vhuiyan MI, Pak ML, Park MA, et al. (2017) PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X. Journal of Biochemistry
Wu H, Zheng W, Eram MS, et al. (2016) Structural basis of arginine asymmetrical dimethylation by PRMT6. The Biochemical Journal
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