Matthew L. Hillwig, Ph.D.
Affiliations: | 2008 | Genetics, Development and Cell Biology | Iowa State University, Ames, IA, United States |
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"Matthew Hillwig"Parents
Sign in to add mentor| Eve S. Wurtele | grad student | 2008 | Iowa State | |
| (Understanding the biological activity of Hypericum species through metabolomics studies.) | ||||
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Publications
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| Xu M, Hillwig ML, Tiernan MS, et al. (2017) Probing Labdane-Related Diterpenoid Biosynthesis in the Fungal Genus Aspergillus. Journal of Natural Products |
| Hillwig ML, Zhu Q, Ittiamornkul K, et al. (2016) Discovery of a Promiscuous Non-Heme Iron Halogenase in Ambiguine Alkaloid Biogenesis: Implication for an Evolvable Enzyme Family for Late-Stage Halogenation of Aliphatic Carbons in Small Molecules. Angewandte Chemie (International Ed. in English) |
| Mafu S, Jia M, Zi J, et al. (2016) Probing the promiscuity of ent-kaurene oxidases via combinatorial biosynthesis. Proceedings of the National Academy of Sciences of the United States of America |
| Zhu Q, Hillwig ML, Doi Y, et al. (2016) Aliphatic Halogenase Enables Late-Stage C-H Functionalization: Selective Synthesis of Brominated Fischerindole Alkaloid with Enhanced Antibacterial Activity. Chembiochem : a European Journal of Chemical Biology |
| Liu X, Hillwig ML, Koharudin LM, et al. (2016) Unified biogenesis of ambiguine, fischerindole, hapalindole and welwitindolinone: identification of a monogeranylated indolenine as a cryptic common biosynthetic intermediate by an unusual magnesium-dependent aromatic prenyltransferase. Chemical Communications (Cambridge, England) |
| Ittiamornkul K, Zhu Q, Gkotsi DS, et al. (2015) Promiscuous indolyl vinyl isonitrile synthases in the biogenesis and diversification of hapalindole-type alkaloids. Chemical Science. 6: 6836-6840 |
| Mafu S, Potter KC, Hillwig ML, et al. (2015) Efficient heterocyclisation by (di)terpene synthases. Chemical Communications (Cambridge, England). 51: 13485-7 |
| Xu M, Hillwig ML, Lane AL, et al. (2014) Characterization of an orphan diterpenoid biosynthetic operon from Salinispora arenicola. Journal of Natural Products. 77: 2144-7 |
| Hillwig ML, Fuhrman HA, Ittiamornkul K, et al. (2014) Identification and characterization of a welwitindolinone alkaloid biosynthetic gene cluster in the stigonematalean Cyanobacterium Hapalosiphon welwitschii. Chembiochem : a European Journal of Chemical Biology. 15: 665-9 |
| Gao W, Sun HX, Xiao H, et al. (2014) Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza. Bmc Genomics. 15: 73 |