William J. Blake, Ph.D.

2003 Boston University, Boston, MA, United States 
Systems Biology, Synthetic Biology
"William Blake"


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James J. Collins grad student 2003 Boston University
 (Development of artificial gene regulatory networks in Saccharomyces cerevisiae: Genetic switches and noise modulation.)
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Dymond JS, Richardson SM, Coombes CE, et al. (2011) Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 477: 471-6
Blake WJ, Balázsi G, Kohanski MA, et al. (2006) Phenotypic consequences of promoter-mediated transcriptional noise. Molecular Cell. 24: 853-65
Volfson D, Marciniak J, Blake WJ, et al. (2006) Origins of extrinsic variability in eukaryotic gene expression. Nature. 439: 861-4
Blake WJ, Collins JJ. (2005) And the noise played on: stochastic gene expression and HIV-1 infection. Cell. 122: 147-9
Kaern M, Elston TC, Blake WJ, et al. (2005) Stochasticity in gene expression: from theories to phenotypes. Nature Reviews. Genetics. 6: 451-64
Isaacs FJ, Blake WJ, Collins JJ. (2005) Molecular biology. Signal processing in single cells. Science (New York, N.Y.). 307: 1886-8
Blake WJ, Isaacs FJ. (2004) Synthetic biology evolves. Trends in Biotechnology. 22: 321-4
Kaern M, Blake WJ, Collins JJ. (2003) The engineering of gene regulatory networks. Annual Review of Biomedical Engineering. 5: 179-206
Blake WJ, KAErn M, Cantor CR, et al. (2003) Noise in eukaryotic gene expression. Nature. 422: 633-7
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