Michael A. Kohanski, Ph.D.

2009 Boston University, Boston, MA, United States 
Systems Biology, Synthetic Biology
"Michael Kohanski"


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James J. Collins grad student 2009 Boston University
 (A systems biology approach to antibiotic-mediated cell death.)
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Lopatkin AJ, Bening SC, Manson AL, et al. (2021) Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371
Kohanski MA, Tharakan A, London NR, et al. (2017) Bactericidal antibiotics promote oxidative damage and programmed cell death in sinonasal epithelial cells. International Forum of Allergy & Rhinology
Dwyer DJ, Camacho DM, Kohanski MA, et al. (2012) Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Molecular Cell. 46: 561-72
Modi SR, Camacho DM, Kohanski MA, et al. (2011) Functional characterization of bacterial sRNAs using a network biology approach. Proceedings of the National Academy of Sciences of the United States of America. 108: 15522-7
Cohen SE, Lewis CA, Mooney RA, et al. (2010) Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 107: 15517-22
Kohanski MA, Dwyer DJ, Collins JJ. (2010) How antibiotics kill bacteria: from targets to networks. Nature Reviews. Microbiology. 8: 423-35
Kohanski MA, DePristo MA, Collins JJ. (2010) Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Molecular Cell. 37: 311-20
Davies BW, Kohanski MA, Simmons LA, et al. (2009) Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Molecular Cell. 36: 845-60
Dwyer DJ, Kohanski MA, Collins JJ. (2009) Role of reactive oxygen species in antibiotic action and resistance. Current Opinion in Microbiology. 12: 482-9
Dwyer DJ, Kohanski MA, Collins JJ. (2008) Networking opportunities for bacteria. Cell. 135: 1153-6
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