Catherine S. Spina, Ph.D.

Affiliations: 
2013 Boston University, Boston, MA, United States 
Area:
Systems Biology, Synthetic Biology
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"Catherine Spina"

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James J. Collins grad student 2013 Boston University
 (A bone marrow-on-a-chip that maintains hematopoietic regenerative capacity in vitro.)
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Publications

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Powers JT, Tsanov KM, Pearson DS, et al. (2016) Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature
Torisawa YS, Spina CS, Mammoto T, et al. (2014) Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nature Methods. 11: 663-9
Urbach A, Yermalovich A, Zhang J, et al. (2014) Lin28 sustains early renal progenitors and induces Wilms tumor. Genes & Development. 28: 971-82
Jasuja R, Costello JC, Singh R, et al. (2014) Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell. 13: 303-10
Kalghatgi S, Spina CS, Costello JC, et al. (2013) Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells. Science Translational Medicine. 5: 192ra85
Morones-Ramirez JR, Winkler JA, Spina CS, et al. (2013) Silver enhances antibiotic activity against gram-negative bacteria. Science Translational Medicine. 5: 190ra81
Modi SR, Lee HH, Spina CS, et al. (2013) Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. Nature. 499: 219-22
Zardi EM, Navarini L, Sambataro G, et al. (2013) Hepatic PPARs: their role in liver physiology, fibrosis and treatment. Current Medicinal Chemistry. 20: 3370-96
Brynildsen MP, Winkler JA, Spina CS, et al. (2013) Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nature Biotechnology. 31: 160-5
Spina CS, Ton L, Yao M, et al. (2007) Selective vitamin D receptor modulators and their effects on colorectal tumor growth. The Journal of Steroid Biochemistry and Molecular Biology. 103: 757-62
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