Catherine S. Spina, Ph.D.

Affiliations: 
2013 Boston University, Boston, MA, United States 
Area:
Systems Biology, Synthetic Biology
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"Catherine Spina"

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James J. Collins grad student 2013 Boston University
 (A bone marrow-on-a-chip that maintains hematopoietic regenerative capacity in vitro.)
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Publications

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Aggen DH, Ager CR, Obradovic AZ, et al. (2020) Blocking Interleukin-1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multi-Dimensional Analyses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Powers JT, Tsanov KM, Pearson DS, et al. (2016) Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature
Torisawa YS, Spina CS, Mammoto T, et al. (2014) Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nature Methods. 11: 663-9
Jasuja R, Costello JC, Singh R, et al. (2014) Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell. 13: 303-10
Kalghatgi S, Spina CS, Costello JC, et al. (2013) Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells. Science Translational Medicine. 5: 192ra85
Morones-Ramirez JR, Winkler JA, Spina CS, et al. (2013) Silver enhances antibiotic activity against gram-negative bacteria. Science Translational Medicine. 5: 190ra81
Modi SR, Lee HH, Spina CS, et al. (2013) Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. Nature. 499: 219-22
Brynildsen MP, Winkler JA, Spina CS, et al. (2013) Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nature Biotechnology. 31: 160-5
Powers J, Spina C, Collins J, et al. (2012) Abstract 2948: The role of the RNA binding protein LIN28B in neuroblastoma Cancer Research. 72: 2948-2948
McKinney-Freeman S, Li H, Curran M, et al. (2009) A Systems Biology Approach to Study the Acquisition of Adult Repopulating Potential During Hematopoietic Stem Cell Ontogeny. Blood. 114: 1479-1479
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