Gerard Manning

1989-1997 Biochemistry Stanford University, Palo Alto, CA 
 2004-2012 Salk Institute for Biological Studies, La Jolla, CA, United States 
 2012- Bioinformatics & Computational Biology Genentech, Inc., San Francisco, CA, United States 
Bioinformatics, Genomics, Oncology, Evolution
"Gerard Manning"

Developed the Drosophila tracheal system as a model for branching morphogenesis, during my PhD with Mark Krasnow at Stanford. Now working on evolutionary genomics, with a focus on protein kinases and still a soft spot for Drosophila and insect evo-devo, and on analysis of large-scale tumor mutation data

Cross-listing: FlyTree


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Mark Krasnow grad student 1989-1997 (FlyTree)


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Tony Hunter collaborator 2002- Salk Institute (DevTree)
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Petrie EJ, Sandow JJ, Lehmann WIL, et al. (2019) Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3. Cell Reports. 28: 3309-3319.e5
Chen MJ, Dixon JE, Manning G. (2017) Genomics and evolution of protein phosphatases. Science Signaling. 10
Foster SA, Whalen DM, Özen A, et al. (2016) Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell
Newton K, Manning G. (2016) Necroptosis and Inflammation. Annual Review of Biochemistry
Foster S, Whalen D, Ozen A, et al. (2016) Abstract 4374: Activation mechanism of oncogenic C-helix shifting mutations in BRAF, EGFR, and HER2 Cancer Research. 76: 4374-4374
Babbitt PC, Bagos PG, Bairoch A, et al. (2015) Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database : the Journal of Biological Databases and Curation. 2015: bav063
Rudolph J, Aliagas I, Crawford JJ, et al. (2015) Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series. Acs Medicinal Chemistry Letters. 6: 711-5
Holliday GL, Bairoch A, Bagos PG, et al. (2015) Key challenges for the creation and maintenance of specialist protein resources. Proteins. 83: 1005-13
Klijn C, Durinck S, Stawiski EW, et al. (2015) A comprehensive transcriptional portrait of human cancer cell lines. Nature Biotechnology. 33: 306-12
Hunter T, Manning G. (2015) The eukaryotic protein kinase superfamily and the emergence of receptor tyrosine kinases Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 1-15
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