Gerard Manning
Affiliations: | 1989-1997 | Biochemistry | Stanford University, Palo Alto, CA |
| 2004-2012 | Salk Institute for Biological Studies, La Jolla, CA, United States | ||
| 2012- | Bioinformatics & Computational Biology | Genentech, Inc., San Francisco, CA, United States |
Area:
Bioinformatics, Genomics, Oncology, EvolutionWebsite:
http://manninglab.orgGoogle:
"Gerard Manning"Bio:
Developed the Drosophila tracheal system as a model for branching morphogenesis, during my PhD with Mark Krasnow at Stanford. Now working on evolutionary genomics, with a focus on protein kinases and still a soft spot for Drosophila and insect evo-devo, and on analysis of large-scale tumor mutation data
Cross-listing: FlyTree
Children
Sign in to add trainee| Eric D. Scheeff | post-doc | 2006-2011 | Salk Institute |
| Scott Anthony Becker | post-doc | 2008-2012 | Salk Institute |
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Publications
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| Petrie EJ, Sandow JJ, Lehmann WIL, et al. (2019) Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3. Cell Reports. 28: 3309-3319.e5 |
| Chen MJ, Dixon JE, Manning G. (2017) Genomics and evolution of protein phosphatases. Science Signaling. 10 |
| Foster SA, Whalen DM, Özen A, et al. (2016) Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell |
| Newton K, Manning G. (2016) Necroptosis and Inflammation. Annual Review of Biochemistry |
| Foster S, Whalen D, Ozen A, et al. (2016) Abstract 4374: Activation mechanism of oncogenic C-helix shifting mutations in BRAF, EGFR, and HER2 Cancer Research. 76: 4374-4374 |
| Babbitt PC, Bagos PG, Bairoch A, et al. (2015) Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database : the Journal of Biological Databases and Curation. 2015: bav063 |
| Rudolph J, Aliagas I, Crawford JJ, et al. (2015) Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series. Acs Medicinal Chemistry Letters. 6: 711-5 |
| Holliday GL, Bairoch A, Bagos PG, et al. (2015) Key challenges for the creation and maintenance of specialist protein resources. Proteins. 83: 1005-13 |
| Klijn C, Durinck S, Stawiski EW, et al. (2015) A comprehensive transcriptional portrait of human cancer cell lines. Nature Biotechnology. 33: 306-12 |
| Hunter T, Manning G. (2015) The eukaryotic protein kinase superfamily and the emergence of receptor tyrosine kinases Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 1-15 |