Mitchell P. Levesque, Ph.D.

2005 Duke University, Durham, NC 
Bioinformatics, Genetics
"Mitchell Levesque"


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Philip N. Benfey grad student 2005 Duke (Plant Biology Tree)
 (Developing comparative genomic tools for identifying novel genes in biological networks.)
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Banik I, Cheng PF, Dooley CM, et al. (2020) NRAS melanoma tumor formation is reduced by p38-MAPK14 activation in zebrafish models and NRAS-mutated human melanoma cells. Pigment Cell & Melanoma Research
Rabbie R, Ansari-Pour N, Cast O, et al. (2020) Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases. Nature Communications. 11: 4306
Teh JL, Erkes DA, Cheng PF, et al. (2020) Activation of CD8+ T cells contributes to anti-tumor effects of CDK4/6 inhibitors plus MEK inhibitors. Cancer Immunology Research
Lazar I, Fabre B, Feng Y, et al. (2020) SPANX control of Lamin A/C modulates nuclear architecture and promotes melanoma growth. Molecular Cancer Research : McR
Vandamme N, Denecker G, Bruneel K, et al. (2020) The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype. Cancer Research
Nguyen MQ, Teh JLF, Purwin TJ, et al. (2020) Targeting PHGDH upregulation reduces glutathione levels and re-sensitizes resistant NRAS mutant melanoma to MEK inhibition. The Journal of Investigative Dermatology
Kaufmann C, Kempf W, Mangana J, et al. (2020) The role of Cyclin D1 and Ki-67 in the development and prognostication of thin melanoma. Histopathology
Uka R, Britschgi C, Krättli A, et al. (2020) Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth. Oncogene
Cheng P, Levesque MP, Dummer R, et al. (2020) Targeting complex, adaptive responses in melanoma therapy. Cancer Treatment Reviews. 86: 101997
Wenzina J, Holzner S, Puujalka E, et al. (2019) Inhibition of p38/MK2 signaling prevents vascular invasion of melanoma. The Journal of Investigative Dermatology
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