Matthew J. Culyba, Ph.D.

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Bioinformatics, Molecular Biology, Immunology
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"Matthew Culyba"

Parents

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Frederic D. Bushman grad student 2008 Penn
 (Catalysis by the poxvirus Holliday junction resolving enzyme.)
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Publications

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Lewis EB, Chen E, Culyba MJ. (2021) DNA cytosine methylation at the lexA promoter of Escherichia coli is stationary phase specific. G3 (Bethesda, Md.)
Selwood T, Larsen BJ, Mo CY, et al. (2018) Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response. Frontiers in Microbiology. 9: 2961
Culyba MJ, Kubiak JM, Mo CY, et al. (2018) Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network. Plos Genetics. 14: e1007405
Mo CY, Culyba MJ, Selwood T, et al. (2017) Inhibitors of LexA autoproteolysis and the bacterial SOS response discovered by an academic-industry partnership. Acs Infectious Diseases
Kubiak JM, Culyba MJ, Liu MY, et al. (2017) A small-molecule inducible synthetic circuit for control of the SOS gene network without DNA damage. Acs Synthetic Biology
Culyba M, Hwang Y, Attar S, et al. (2012) Bulged DNA substrates for identifying poxvirus resolvase inhibitors. Nucleic Acids Research. 40: e124
Culyba MJ, Hwang Y, Hu JY, et al. (2010) Metal cofactors in the structure and activity of the fowlpox resolvase. Journal of Molecular Biology. 399: 182-95
Culyba MJ, Hwang Y, Minkah N, et al. (2009) DNA binding and cleavage by the fowlpox virus resolvase. The Journal of Biological Chemistry. 284: 1190-201
Culyba MJ, Minkah N, Hwang Y, et al. (2007) DNA branch nuclease activity of vaccinia A22 resolvase. The Journal of Biological Chemistry. 282: 34644-52
Culyba MJ, Harrison JE, Hwang Y, et al. (2006) DNA cleavage by the A22R resolvase of vaccinia virus. Virology. 352: 466-76
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