Rumen Kostadinov, Ph.D.

Affiliations: 
2012 Genomics and Computational Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Genetics, Medicine and Surgery, Cell Biology
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"Rumen Kostadinov"

Parents

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Carlo C. Maley grad student 2012 Penn
 (Evolutionary dynamics of neoplastic cell populations in Barrett's esophagus.)
Rafael A. Irizarry post-doc 2012-2014 Johns Hopkins Bloomberg School of Public Health (MathTree)

Collaborators

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Mary  K. Kuhner collaborator 2006-2012 Penn (Evolution Tree)
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Publications

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Guest E, Yoo B, Kostadinov R, et al. (2019) Single Cell Sequencing Reveals Heterogeneity of Gene Expression in KMT2A Rearranged Infant ALL at Relapse Compared to Diagnosis Blood. 134: 2756-2756
Yoo B, Farooqi MS, Kostadinov R, et al. (2019) Abstract 3649: Allelic imbalance in KMT2A-rearranged infant acute lymphoblastic leukemia Cancer Research. 79: 3649-3649
Kostadinov R, Yoo B, Farooqi MS, et al. (2018) Whole Genome Bisulfite Sequencing (WGBS) Robustly Measures the Pharmacodynamic Effect of Decitabine/Vorinostat Epigenetic Treatment in Relapsed Pediatric ALL Demonstrating Potent Hypomethylation Associated with Upregulation of PRC2 and TP53 Targets Blood. 132: 918-918
Somarelli JA, Ware KE, Kostadinov R, et al. (2016) PhyloOncology: Understanding cancer through phylogenetic analysis. Biochimica Et Biophysica Acta
Kostadinov R, Maley CC, Kuhner MK. (2016) Bulk Genotyping of Biopsies Can Create Spurious Evidence for Hetereogeneity in Mutation Content. Plos Computational Biology. 12: e1004413
Kuhner MK, Kostadinov R, Reid BJ. (2016) Limitations of the driver/passenger model in cancer prevention. Cancer Prevention Research (Philadelphia, Pa.)
Cutler J, Tahir R, Kostadinov R, et al. (2016) Proteomic/Transcriptomic Signatures of Infant MLL-r Rearranged B-ALL at Diagnosis and Relapse Reveal Lineage Plasticity and Diagnostic Heterogeneity Blood. 128: 2697-2697
Kostadinov R, Farooqi M, Yoo B, et al. (2016) Landscape of Somatic Mutations and Gene Expression Changes in Relapsed Infant MLL-Rearranged Acute Lymphoblastic Leukemia Blood. 128: 1735-1735
Kostadinov R, Scharpf R, Brown P. (2015) Identifying Subclonal Epigenetic Changes Driving Chemoresistance in Infant MLL-r Acute Lymphoblastic Leukemias Blood. 126: 809-809
Li X, Galipeau PC, Paulson TG, et al. (2014) Temporal and spatial evolution of somatic chromosomal alterations: a case-cohort study of Barrett's esophagus. Cancer Prevention Research (Philadelphia, Pa.). 7: 114-27
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