Paul A. Grimsrud, Ph.D.

Affiliations: 
2008 Biochemistry, Molecular Bio, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biochemistry, Molecular Biology
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David A. Bernlohr grad student 2008 UMN
 (Proteomic and biochemical analysis of adipose protein carbonylation in obesity linked insulin resistance.)
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Publications

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Anderson KA, deSouza B, Castellano-Escuder P, et al. (2025) SIRT4 Controls Macrophage Function and Wound Healing through Control of Protein Itaconylation in Mice. Biorxiv : the Preprint Server For Biology
Keenan EK, Bareja A, Lam Y, et al. (2024) Cysteine -acetylation is a post-translational modification involved in metabolic regulation. Biorxiv : the Preprint Server For Biology
Koves TR, Zhang GF, Davidson MT, et al. (2023) Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles. Cell Metabolism
Muoio DM, Williams AS, Grimsrud PA. (2022) Mitochondrial lysine acylation and cardiometabolic stress: Truth or consequence? Current Opinion in Physiology. 27
Trub AG, Wagner GR, Anderson KA, et al. (2022) Statin therapy inhibits fatty acid synthase via dynamic protein modifications. Nature Communications. 13: 2542
Bhatt DP, Mills CA, Anderson KA, et al. (2022) Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice. The Journal of Biological Chemistry. 101723
Williams AS, Koves TR, Pettway YD, et al. (2021) Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome. Iscience. 25: 103635
Davidson MT, Grimsrud P, Lai L, et al. (2020) Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure. Circulation Research
Williams AS, Koves TR, Davidson MT, et al. (2019) Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction. Cell Metabolism
Fisher-Wellman KH, Draper JA, Davidson MT, et al. (2019) Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics. Cell Reports. 26: 1557-1572.e8
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