John Overington

Affiliations: 
European Bioinformatics Institute, Hinxton, England, United Kingdom 
Area:
Drug Discovery Informatics
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"John Overington"

Children

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Ben Stauch grad student 2008-2012 Cambridge
Felix Krueger grad student 2009-2013 Cambridge
Rita Santos grad student 2010-2014 Cambridge
Gerard JP van Westen post-doc 2012-2015 EMBL-EBI (Chemistry Tree)
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Publications

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Hingorani AD, Kuan V, Finan C, et al. (2019) Improving the odds of drug development success through human genomics: modelling study. Scientific Reports. 9: 18911
Oprea TI, Bologa CG, Brunak S, et al. (2018) Unexplored therapeutic opportunities in the human genome. Nature Reviews. Drug Discovery
Oprea TI, Bologa CG, Brunak S, et al. (2018) Unexplored therapeutic opportunities in the human genome. Nature Reviews. Drug Discovery
Tresadern G, Trabanco AA, Pérez-Benito L, et al. (2017) Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling. Journal of Chemical Information and Modeling
Mugumbate G, Mendes V, Blaszczyk M, et al. (2017) Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach. Frontiers in Pharmacology. 8: 681
Martínez-Jiménez F, Overington JP, Al-Lazikani B, et al. (2017) Rational design of non-resistant targeted cancer therapies. Scientific Reports. 7: 46632
Finan C, Gaulton A, Kruger FA, et al. (2017) The druggable genome and support for target identification and validation in drug development. Science Translational Medicine. 9
Santos R, Ursu O, Gaulton A, et al. (2016) A comprehensive map of molecular drug targets. Nature Reviews. Drug Discovery
Nguyen DT, Mathias S, Bologa C, et al. (2016) Pharos: Collating protein information to shed light on the druggable genome. Nucleic Acids Research
Gaulton A, Hersey A, Nowotka M, et al. (2016) The ChEMBL database in 2017. Nucleic Acids Research
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