Xuebing Wu, Ph.D.
|2010-2014||Koch Institute||Massachusetts Institute of Technology, Cambridge, MA, United States|
|2014-2018||David Bartel Lab||Whitehead Institute for Biomedical Research (MIT)|
|2018-||Medicine; Systems Biology||Columbia University, New York, NY|
Xuebing Wu, PhD, joined Columbia University as an assistant professor in November, 2018. Dr. Wu received his BS and MS in Control Science and Engineering from Tsinghua University, Beijing. He pursued his PhD in Computational and Systems Biology at MIT with Phillip Sharp and Christopher Burge. He worked as an Helen Hay Whitney Fellow in Dr. David Bartel’s lab at Whitehead Institute/MIT prior to joining Columbia. The Wu lab integrates CRISPR, genomics, and machine learning to both decode and target RNA in human health and disease. The Wu lab seeks to bridge the discovery of basic mechanisms of gene regulation with the development of novel therapeutics for human diseases, focusing on cancer and cardiometabolic diseases.
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|Zhang C, Konermann S, Brideau NJ, et al. (2018) Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Cell. 175: 212-223.e17|
|Tycko J, Barrera LA, Huston NC, et al. (2018) Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells. Nature Communications. 9: 3542|
|Li Z, Jiang X, Chen P, et al. (2018) Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines. Oncology Letters. 16: 4033-4042|
|Tycko J, Barrera LA, Huston NC, et al. (2018) Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells. Nature Communications. 9: 2962|
|Jiang W, Wei Y, Long Y, et al. (2018) A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in . Elife. 7|
|Wu K, Feng G, Liu Y, et al. (2018) Enhanced hydrolysis of mechanically pretreated cellulose in water/CO system. Bioresource Technology. 261: 28-35|
|Wu K, Yang M, Hu H, et al. (2018) ZrMn oxides for aqueous-phase ketonization of acetic acid: effect of crystal and porosity. Chemistry, An Asian Journal|
|Liu XS, Wu H, Krzisch M, et al. (2018) Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell|
|Chiu AC, Suzuki HI, Wu X, et al. (2018) Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP. Molecular Cell|
|Jiang W, Wei Y, Long Y, et al. (2018) Author response: A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans Elife|