David P. Lane
Affiliations: | Institute of Molecular and Cell Biology (A-STAR), Singapore, Singapore |
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"David Lane"Bio:
Institute of Molecular and Cell Biology (A-STAR), Proteos, 61 Biopolis Drive, Singapore 138673
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Nicholas Avrion Mitchison | grad student | UCL (London) (Cell Biology Tree) |
Children
Sign in to add trainee| Ted Hupp | post-doc | (Neurotree) | |
| Jonathan Wilson Yewdell | post-doc | Imperial College (Cell Biology Tree) |
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Publications
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| Spiegelberg D, Mortensen ACL, Palupi KD, et al. (2020) The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model. Frontiers in Oncology. 10: 1717 |
| Turnquist C, Beck JA, Horikawa I, et al. (2019) Radiation-induced astrocyte senescence is rescued by Δ133p53. Neuro-Oncology |
| Ladds MJGW, van Leeuwen IMM, Drummond CJ, et al. (2018) A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage. Nature Communications. 9: 1107 |
| von Muhlinen N, Horikawa I, Alam F, et al. (2018) p53 isoforms regulate premature aging in human cells. Oncogene |
| Muller P, Chan JM, Simoncik O, et al. (2017) Evidence for allosteric effects on p53 oligomerization induced by phosphorylation. Protein Science : a Publication of the Protein Society |
| Siau JW, Coffill CR, Zhang WV, et al. (2016) Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens. Scientific Reports. 6: 33972 |
| Tan YS, Reeks J, Brown CJ, et al. (2016) Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design. The Journal of Physical Chemistry Letters |
| Tan YS, Lane DP, Verma CS. (2016) Stapled peptide design: principles and roles of computation. Drug Discovery Today |
| Turnquist C, Horikawa I, Foran E, et al. (2016) p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration. Cell Death and Differentiation |
| Kannan S, Lane DP, Verma CS. (2016) Long range recognition and selection in IDPs: the interactions of the C-terminus of p53. Scientific Reports. 6: 23750 |