Thomas Down, PhD

Affiliations: 
Gurdon Institute 
Website:
http://www.gurdon.cam.ac.uk/down.html
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Publications

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Howe KL, Bolt BJ, Cain S, et al. (2016) WormBase 2016: expanding to enable helminth genomic research. Nucleic Acids Research. 44: D774-80
Geihs M, Yan Y, Walter K, et al. (2015) An interactive genome browser of association results from the UK10K cohorts project. Bioinformatics (Oxford, England)
Puszyk W, Down T, Grimwade D, et al. (2013) The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells. The Embo Journal. 32: 1941-52
Gemma C, Ramagopalan SV, Down TA, et al. (2013) Inactive or moderately active human promoters are enriched for inter-individual epialleles. Genome Biology. 14: R43
Evans AL, Faial T, Gilchrist MJ, et al. (2012) Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. Plos One. 7: e33346
Saied MH, Marzec J, Khalid S, et al. (2012) Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats. Plos One. 7: e33213
Movassagh M, Choy MK, Knowles DA, et al. (2011) Distinct epigenomic features in end-stage failing human hearts. Circulation. 124: 2411-22
Rakyan VK, Down TA, Balding DJ, et al. (2011) Epigenome-wide association studies for common human diseases. Nature Reviews. Genetics. 12: 529-41
Cheung MS, Down TA, Latorre I, et al. (2011) Systematic bias in high-throughput sequencing data and its correction by BEADS. Nucleic Acids Research. 39: e103
Feber A, Wilson GA, Zhang L, et al. (2011) Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors. Genome Research. 21: 515-24
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