Jason H. Yang, PhD
Affiliations: | 2019- | Microbiology, Biochemistry and Molecular Genetics | Rutgers New Jersey Medical School |
Area:
systems biology, biomedical engineering, infectious diseaseWebsite:
https://www.jasonyanglab.orgGoogle:
"Jason H Yang"Parents
Sign in to add mentor| Ergin Atalar | research assistant | 2002-2002 | Johns Hopkins Medical School |
| Raimond L. Winslow | research assistant | 2003-2006 | Johns Hopkins |
| Jeffrey J. Saucerman | grad student | 2006-2012 | UVA |
| James J. Collins | post-doc | 2012-2019 | MIT |
Collaborators
Sign in to add collaborator| Jin Zhang | collaborator | 2010-2011 | Johns Hopkins Medical School |
| Bernhard O. Palsson | collaborator | 2015-2017 | UCSD |
BETA: Related publications
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Publications
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| Ofori-Anyinam B, Hamblin M, Coldren ML, et al. (2024) Catalase activity deficiency sensitizes multidrug-resistant Mycobacterium tuberculosis to the ATP synthase inhibitor bedaquiline. Nature Communications. 15: 9792 |
| Lopatkin AJ, Yang JH. (2021) Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure. Frontiers in Digital Health. 3 |
| Kim GL, Hooven TA, Norambuena J, et al. (2021) Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection. Mbio. e0081421 |
| Lopatkin AJ, Bening SC, Manson AL, et al. (2021) Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371 |
| Lopatkin AJ, Stokes JM, Zheng EJ, et al. (2019) Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nature Microbiology |
| Yang JH, Wright SN, Hamblin M, et al. (2019) A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. Cell |
| Yang JH, Bhargava P, McCloskey D, et al. (2017) Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host & Microbe. 22: 757-765.e3 |
| Yang JH, Bening SC, Collins JJ. (2017) Antibiotic efficacy-context matters. Current Opinion in Microbiology. 39: 73-80 |
| Takahashi N, Gruber CC, Yang JH, et al. (2017) Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America |
| Meylan S, Porter CB, Yang JH, et al. (2017) Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. Cell Chemical Biology |