Jason H. Yang, PhD

Affiliations: 
2019- Microbiology, Biochemistry and Molecular Genetics Rutgers New Jersey Medical School 
Area:
systems biology, biomedical engineering, infectious disease
Website:
https://www.jasonyanglab.org
Google:
"Jason H Yang"

Parents

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Ergin Atalar research assistant 2002-2002 Johns Hopkins Medical School
Raimond L. Winslow research assistant 2003-2006 Johns Hopkins
Jeffrey J. Saucerman grad student 2006-2012 UVA
James J. Collins post-doc 2012-2019 MIT

Collaborators

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Jin Zhang collaborator 2010-2011 Johns Hopkins Medical School
Bernhard O. Palsson collaborator 2015-2017 UCSD
BETA: Related publications

Publications

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Ofori-Anyinam B, Hamblin M, Coldren ML, et al. (2024) Catalase activity deficiency sensitizes multidrug-resistant Mycobacterium tuberculosis to the ATP synthase inhibitor bedaquiline. Nature Communications. 15: 9792
Lopatkin AJ, Yang JH. (2021) Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure. Frontiers in Digital Health. 3
Kim GL, Hooven TA, Norambuena J, et al. (2021) Growth and Stress Tolerance Comprise Independent Metabolic Strategies Critical for Staphylococcus aureus Infection. Mbio. e0081421
Lopatkin AJ, Bening SC, Manson AL, et al. (2021) Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371
Lopatkin AJ, Stokes JM, Zheng EJ, et al. (2019) Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nature Microbiology
Yang JH, Wright SN, Hamblin M, et al. (2019) A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. Cell
Yang JH, Bhargava P, McCloskey D, et al. (2017) Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host & Microbe. 22: 757-765.e3
Yang JH, Bening SC, Collins JJ. (2017) Antibiotic efficacy-context matters. Current Opinion in Microbiology. 39: 73-80
Takahashi N, Gruber CC, Yang JH, et al. (2017) Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America
Meylan S, Porter CB, Yang JH, et al. (2017) Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. Cell Chemical Biology
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