Jason H. Yang, PhD

2019- Microbiology, Biochemistry and Molecular Genetics Rutgers New Jersey Medical School 
systems biology
"Jason H Yang"


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Ergin Atalar research assistant 2002-2002 Johns Hopkins Medical School
Raimond L. Winslow research assistant 2003-2006 Johns Hopkins
Jeff Saucerman grad student 2006-2012 UVA
James J. Collins post-doc 2012-2019 MIT


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Jin Zhang collaborator 2010-2011 Johns Hopkins Medical School
Bernhard O. Palsson collaborator 2015-2017 UCSD
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Lopatkin AJ, Bening SC, Manson AL, et al. (2021) Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science (New York, N.Y.). 371
Chivukula RR, Montoro DT, Leung HM, et al. (2020) A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nature Medicine
Lopatkin AJ, Stokes JM, Zheng EJ, et al. (2019) Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nature Microbiology
Yang JH, Wright SN, Hamblin M, et al. (2019) A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action. Cell
Yang JH, Bhargava P, McCloskey D, et al. (2017) Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host & Microbe. 22: 757-765.e3
Yang JH, Bening SC, Collins JJ. (2017) Antibiotic efficacy-context matters. Current Opinion in Microbiology. 39: 73-80
Takahashi N, Gruber CC, Yang JH, et al. (2017) Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America
Meylan S, Porter CB, Yang JH, et al. (2017) Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. Cell Chemical Biology
Lobritz MA, Belenky P, Porter CB, et al. (2015) Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America
Dwyer DJ, Belenky PA, Yang JH, et al. (2014) Antibiotics induce redox-related physiological alterations as part of their lethality. Proceedings of the National Academy of Sciences of the United States of America. 111: E2100-9
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