Des Higgins, PhD

Affiliations: 
Conway Institute University College Dublin, Dublin, County Dublin, Ireland 
Area:
Bioinformatics
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"Des Higgins"
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Publications

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Duffy DJ, Krstic A, Halasz M, et al. (2015) Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget
Boyce K, Sievers F, Higgins DG. (2015) Instability in progressive multiple sequence alignment algorithms. Algorithms For Molecular Biology : Amb. 10: 26
Schwarzl T, Higgins DG, Kolch W, et al. (2015) Measuring Transcription Rate Changes via Time-Course 4-Thiouridine Pulse-Labelling Improves Transcriptional Target Identification. Journal of Molecular Biology. 427: 3368-74
Jehl P, Sievers F, Higgins DG. (2015) OD-seq: outlier detection in multiple sequence alignments. Bmc Bioinformatics. 16: 269
Boyce K, Sievers F, Higgins DG. (2015) Reply to Tan et al.: Differences between real and simulated proteins in multiple sequence alignments. Proceedings of the National Academy of Sciences of the United States of America. 112: E101
Sievers F, Higgins DG. (2014) Clustal omega. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. 48: 3.13.1-3.13.16
Sievers F, Hughes GM, Higgins DG. (2014) Systematic exploration of guide-tree topology effects for small protein alignments. Bmc Bioinformatics. 15: 338
Yin J, Morrissey ME, Shine L, et al. (2014) Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis. Bmc Genomics. 15: 825
Holland LM, Schröder MS, Turner SA, et al. (2014) Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans. Plos Pathogens. 10: e1004365
Boyce K, Sievers F, Higgins DG. (2014) Simple chained guide trees give high-quality protein multiple sequence alignments. Proceedings of the National Academy of Sciences of the United States of America. 111: 10556-61
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