Kevin D. Costa, Ph.D.

Bioengineering University of California, San Diego, La Jolla, CA 
cardiac biomechanics, tissue engineering, atomic force microscopy
"Kevin Costa"
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Lee JJ, Rao S, Kaushik G, et al. (2018) Dehomogenized Elastic Properties of Heterogeneous Layered Materials in AFM Indentation Experiments. Biophysical Journal. 114: 2717-2731
Zhou N, Lee JJ, Stoll S, et al. (2017) Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 44: 701-715
Zhou N, Lee JJ, Stoll S, et al. (2016) Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension. Cardiovascular Research
Lee JJ, Galatioto J, Rao S, et al. (2016) Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome. Annals of Biomedical Engineering
Hernandez M, Patzig J, Mayoral SR, et al. (2016) Mechanostimulation Promotes Nuclear and Epigenetic Changes in Oligodendrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 806-13
Cashman TJ, Josowitz R, Johnson BV, et al. (2016) Human engineered cardiac tissues created using induced pluripotent stem cells reveal functional characteristics of BRAF-mediated hypertrophic cardiomyopathy Plos One. 11
Kerscher P, Turnbull IC, Hodge AJ, et al. (2015) Direct hydrogel encapsulation of pluripotent stem cells enables ontomimetic differentiation and growth of engineered human heart tissues. Biomaterials. 83: 383-395
Turnbull IC, Eltoukhy AA, Fish KM, et al. (2015) Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression. Molecular Therapy : the Journal of the American Society of Gene Therapy
Chen G, Li S, Karakikes I, et al. (2015) Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circulation. Arrhythmia and Electrophysiology. 8: 193-202
Ishikawa K, Fish K, Aguero J, et al. (2015) Stem cell factor gene transfer improves cardiac function after myocardial infarction in swine. Circulation. Heart Failure. 8: 167-74
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