David P Nusinow, Ph.D.

Affiliations: 
2004-2008 Cell, Molecular, and Developmental Biology Sackler School of Graduate Biomedical Sciences (Tufts University) 
 2009-2011 Genetics Division Brigham and Women's Hospital, Boston 
 2012- Cell Biology Harvard Medical School, Boston, MA, United States 
Area:
Proteomics, Cancer, Computational Biology, Genetics
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"David Nusinow"
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Publications

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Huttlin EL, Bruckner RJ, Navarrete-Perea J, et al. (2021) Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Cell
Kuljanin M, Mitchell DC, Schweppe DK, et al. (2021) Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nature Biotechnology
Nusinow DP, Szpyt J, Ghandi M, et al. (2020) Quantitative Proteomics of the Cancer Cell Line Encyclopedia. Cell. 180: 387-402.e16
Li J, Paulo JA, Nusinow DP, et al. (2019) Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast. Cell Reports. 29: 2092-2104.e4
Erickson BK, Mintseris J, Schweppe DK, et al. (2019) Active instrument engagement combined with a real-time database search for improved performance of sample multiplexing workflows. Journal of Proteome Research
Cassa CA, Weghorn D, Balick DJ, et al. (2019) Reply to 'Selective effects of heterozygous protein-truncating variants'. Nature Genetics. 51: 3-4
Cassa CA, Weghorn D, Balick DJ, et al. (2017) Estimating the selective effects of heterozygous protein-truncating variants from human exome data. Nature Genetics
Chick JM, Kolippakkam D, Nusinow DP, et al. (2015) Erratum: A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides. Nature Biotechnology. 33: 882
Chick JM, Kolippakkam D, Nusinow DP, et al. (2015) A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides. Nature Biotechnology. 33: 743-9
McAlister GC, Nusinow DP, Jedrychowski MP, et al. (2014) MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Analytical Chemistry. 86: 7150-8
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