Takashi Ochi

Affiliations: 
MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
Area:
Structure Biology
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"Takashi Ochi"
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Publications

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Ochi T, Quarantotti V, Lin H, et al. (2020) CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions. Structure (London, England : 1993)
Wu Q, Liang S, Ochi T, et al. (2019) Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways. Progress in Biophysics and Molecular Biology
Wang JL, Duboc C, Wu Q, et al. (2018) Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature Structural & Molecular Biology
Chang HH, Watanabe G, Gerodimos CA, et al. (2016) Different DNA End Configurations Dictate Which NHEJ Components are Most Important for Joining Efficiency. The Journal of Biological Chemistry
Wu Q, Paul A, Su D, et al. (2016) Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites. Molecular Cell
Murray JE, van der Burg M, IJspeert H, et al. (2015) Mutations in the NHEJ component XRCC4 cause primordial dwarfism. American Journal of Human Genetics. 96: 412-24
Ochi T, Blackford AN, Coates J, et al. (2015) DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science (New York, N.Y.). 347: 185-8
Ascher DB, Jubb HC, Pires DEV, et al. (2015) Protein-protein interactions: Structures and druggability Nato Science For Peace and Security Series a: Chemistry and Biology. 38: 141-163
Ochi T, Wu Q, Blundell TL. (2014) The spatial organization of non-homologous end joining: from bridging to end joining. Dna Repair. 17: 98-109
Ochi T, Gu X, Blundell TL. (2013) Structure of the catalytic region of DNA ligase IV in complex with an Artemis fragment sheds light on double-strand break repair. Structure (London, England : 1993). 21: 672-9
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