Harmen J. Bussemaker, Ph.D.
Affiliations: | 2001- | Biological Sciences | Columbia University, New York, NY |
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Parents
Sign in to add mentor| Matthieu Hubertus Joseph Jacob Ernst | grad student | 1989-1995 | Utrecht |
| Eric D. Siggia | post-doc | Rockefeller |
Children
Sign in to add trainee| Barrett C. Foat | grad student | 2007 | Columbia |
| Gabor Halasz | grad student | 2009 | Columbia |
| Lucas D. Ward | grad student | 2010 | Columbia (Computational Biology Tree) |
| Ronald G. Tepper | grad student | 2011 | Columbia |
| Eunjee Lee | grad student | 2012 | Columbia |
| Mina Fazlollahi | grad student | 2013 | Columbia |
| Allan Lazarovici | grad student | 2014 | Columbia |
| Todd Riley | post-doc | Columbia (Computational Biology Tree) | |
| Junbai Wang | post-doc | Columbia | |
| Xiang-Jun Lu | research scientist | Columbia |
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Publications
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| Li X, Lappalainen T, Bussemaker HJ. (2023) Identifying genetic regulatory variants that affect transcription factor activity. Cell Genomics. 3: 100382 |
| Trauernicht M, Rastogi C, Manzo SG, et al. (2023) Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements. Nucleic Acids Research. 51: 9690-9702 |
| Nora EP, Aerts S, Wittkopp PJ, et al. (2023) Emerging questions in transcriptional regulation. Cell Systems. 14: 247-251 |
| FitzPatrick VD, Leemans C, van Arensbergen J, et al. (2023) Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR. Nucleic Acids Research |
| Feng S, Rastogi C, Loker R, et al. (2022) Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors. Nature Communications. 13: 3808 |
| Flynn ED, Tsu AL, Kasela S, et al. (2022) Transcription factor regulation of eQTL activity across individuals and tissues. Plos Genetics. 18: e1009719 |
| Zhang L, Rube HT, Vakulskas CA, et al. (2020) Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes. Nucleic Acids Research |
| Kribelbauer JF, Loker RE, Feng S, et al. (2020) Context-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins. Molecular Cell |
| Kribelbauer JF, Lu XJ, Rohs R, et al. (2019) Towards a mechanistic understanding of DNA methylation readout by transcription factors. Journal of Molecular Biology |
| Sánchez-Higueras C, Rastogi C, Voutev R, et al. (2019) In vivo Hox binding specificity revealed by systematic changes to a single cis regulatory module. Nature Communications. 10: 3597 |