Albert Berghuis

Affiliations: 
Biochemistry McGill University, Montreal, QC, Canada 
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"Albert Berghuis"
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Zieliński M, Blanchet J, Hailemariam S, et al. (2022) Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One. 17: e0269684
Golkar T, Bassenden AV, Maiti K, et al. (2021) Structural basis for plazomicin antibiotic action and resistance. Communications Biology. 4: 729
Bassenden AV, Dumalo L, Park J, et al. (2021) Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Scientific Reports. 11: 11614
Zieliński M, Park J, Sleno B, et al. (2021) Structural and functional insights into esterase-mediated macrolide resistance. Nature Communications. 12: 1732
Park J, Pandya VR, Ezekiel SJ, et al. (2020) Phosphonate and Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthases: A Structure-Guided Perspective. Frontiers in Chemistry. 8: 612728
Bassenden AV, Park J, Rodionov D, et al. (2020) Revisiting the Catalytic Cycle and Kinetic Mechanism of ANT(2″): A Structural and Kinetic Study. Acs Chemical Biology
Toulouse JL, Yachnin BJ, Ruediger EH, et al. (2019) Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues. Acs Omega. 4: 10056-10069
Golkar T, Zieliński M, Berghuis AM. (2018) Look and Outlook on Enzyme-Mediated Macrolide Resistance. Frontiers in Microbiology. 9: 1942
Caldwell SJ, Berghuis AM. (2018) Plasticity of aminoglycoside binding to antibiotic kinase APH(2")-Ia. Antimicrobial Agents and Chemotherapy
Park J, Rodionov D, De Schutter JW, et al. (2017) Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. Plos One. 12: e0186447
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