Amer Alam
Affiliations: | University of Texas Southwestern Medical Center, Dallas, TX, United States |
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"Amer Alam"Parents
Sign in to add mentorYouxing Jiang | grad student | UT Southwestern | |
Kaspar P. Locher | post-doc | ETH Zürich |
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Publications
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Alam A, Locher KP. (2023) Structure and Mechanism of Human ABC Transporters. Annual Review of Biophysics |
Nosol K, Romane K, Irobalieva RN, et al. (2020) Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proceedings of the National Academy of Sciences of the United States of America |
Olsen JA, Alam A, Kowal J, et al. (2019) Structure of the human lipid exporter ABCB4 in a lipid environment. Nature Structural & Molecular Biology |
Alam A, Kowal J, Broude E, et al. (2019) Structural insight into substrate and inhibitor discrimination by human P-glycoprotein. Science (New York, N.Y.). 363: 753-756 |
Alam A, Küng R, Kowal J, et al. (2018) Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proceedings of the National Academy of Sciences of the United States of America |
Alam A, Woo JS, Schmitz J, et al. (2016) Structural basis of transcobalamin recognition by human CD320 receptor. Nature Communications. 7: 12100 |
Alam A, Jiang Y. (2011) Structural studies of ion selectivity in tetrameric cation channels Journal of General Physiology. 137: 397-403 |
Derebe MG, Zeng W, Li Y, et al. (2011) Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore. Proceedings of the National Academy of Sciences of the United States of America. 108: 592-7 |
Derebe MG, Sauer DB, Zeng W, et al. (2011) Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proceedings of the National Academy of Sciences of the United States of America. 108: 598-602 |
Alam A, Jiang Y. (2009) High-resolution structure of the open NaK channel Nature Structural and Molecular Biology. 16: 30-34 |