Hooman Hefzi, Ph.D.

2013-2018 Bioengineering University of California, San Diego, La Jolla, CA 
"Hooman Hefzi"
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Gutierrez JM, Feizi A, Li S, et al. (2020) Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion. Nature Communications. 11: 68
Julie la Cour Karottki K, Hefzi H, Xiong K, et al. (2019) Awakening dormant glycosyltransferases in CHO cells with CRISPRa. Biotechnology and Bioengineering
Ley D, Pereira S, Pedersen LE, et al. (2019) Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion. Metabolic Engineering
Pristovsek N, Nallapereddy S, Grav LM, et al. (2019) Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering. Acs Synthetic Biology
Brunk E, Chang RL, Xia J, et al. (2018) Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow. Proceedings of the National Academy of Sciences of the United States of America
Abdel-Haleem AM, Hefzi H, Mineta K, et al. (2018) Functional interrogation of Plasmodium genus metabolism identifies species- and stage-specific differences in nutrient essentiality and drug targeting. Plos Computational Biology. 14: e1005895
Hefzi H, Ang KS, Hanscho M, et al. (2016) A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Systems. 3: 434-443.e8
Swainston N, Smallbone K, Hefzi H, et al. (2016) Recon 2.2: from reconstruction to model of human metabolism. Metabolomics : Official Journal of the Metabolomic Society. 12: 109
Golabgir A, Gutierrez JM, Hefzi H, et al. (2016) Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow. Biotechnology Advances
Hefzi H, Palsson BO, Lewis NE. (2013) Reconstruction of Genome-Scale Metabolic Networks Handbook of Systems Biology. 229-250
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