Hooman Hefzi, Ph.D.
Affiliations: | 2013-2018 | Bioengineering | University of California, San Diego, La Jolla, CA |
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"Hooman Hefzi"
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Publications
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| Kim SH, Shin S, Baek M, et al. (2023) Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening. Metabolic Engineering |
| Masson HO, Karottki KJC, Tat J, et al. (2023) From observational to actionable: rethinking omics in biologics production. Trends in Biotechnology |
| Ha TK, Òdena A, Karottki KJC, et al. (2022) Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and Bioengineering |
| Xiong K, Karottki KJC, Hefzi H, et al. (2021) Erratum: An optimized genome-wide, virus-free CRISPR screen for mammalian cells. Cell Reports Methods. 1: 100115 |
| Spahn PN, Zhang X, Hu Q, et al. (2021) Restoration of DNA Repair Mitigates Genome Instability and Increases Productivity of Chinese Hamster Ovary Cells. Biotechnology and Bioengineering |
| Xiong K, Karottki KJC, Hefzi H, et al. (2021) An optimized genome-wide, virus-free CRISPR screen for mammalian cells. Cell Reports Methods. 1 |
| Shamie I, Duttke SH, Karottki KJC, et al. (2021) A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells. Nar Genomics and Bioinformatics. 3: lqab061 |
| Karottki KJC, Hefzi H, Li S, et al. (2021) A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes. Metabolic Engineering |
| Gutierrez JM, Feizi A, Li S, et al. (2020) Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion. Nature Communications. 11: 68 |
| Julie la Cour Karottki K, Hefzi H, Xiong K, et al. (2019) Awakening dormant glycosyltransferases in CHO cells with CRISPRa. Biotechnology and Bioengineering |