David B. Sauer

Affiliations: 
2021- Centre for Medicines Discovery University of Oxford, Oxford, United Kingdom 
Area:
Membrane proteins
Website:
http://davidbsauer.com
Google:
"https://scholar.google.com/citations?sortby=pubdate&hl=en&user=F9G61tAAAAAJ&view_op=list_works"

Parents

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Jennifer Hovis research assistant 2003-2005 Purdue (Chemistry Tree)
Youxing Jiang grad student 2005-2012 University of Texas Southwester Medical Center
Da-Neng Wang post-doc 2012-2021 NYU School of Medicine (Microtree)
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Publications

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Liang Q, Chi G, Cirqueira L, et al. (2024) The binding and mechanism of a positive allosteric modulator of Kv3 channels. Nature Communications. 15: 2533
Sauer DB, Marden JJ, Sudar JC, et al. (2022) Structural basis of ion - substrate coupling in the Na-dependent dicarboxylate transporter VcINDY. Nature Communications. 13: 2644
Brawley DN, Sauer DB, Li J, et al. (2022) Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus. Nature Chemical Biology
Sauer DB, Wang B, Sudar JC, et al. (2021) The ups and downs of elevator-type di-/tricarboxylate membrane transporters. The Febs Journal
Sauer DB, Song J, Wang B, et al. (2021) Structure and inhibition mechanism of the human citrate transporter NaCT. Nature
Sauer DB, Trebesch N, Marden JJ, et al. (2020) Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife. 9
Sauer DB, Wang DN. (2019) Predicting the Optimal Growth Temperatures of Prokaryotes using only Genome Derived Features. Bioinformatics (Oxford, England)
Sauer DB, Karpowich NK, Song JM, et al. (2015) Rapid Bioinformatic Identification of Thermostabilizing Mutations. Biophysical Journal. 109: 1420-8
Sauer DB, Karpowich NK, Wang D. (2015) Bioinformatic Methods for the Rapid Identification of Thermostabilizing Mutants Biophysical Journal. 108: 92a
Lam YL, Zeng W, Sauer DB, et al. (2014) The conserved potassium channel filter can have distinct ion binding profiles: structural analysis of rubidium, cesium, and barium binding in NaK2K. The Journal of General Physiology. 144: 181-92
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