Marko Hyvonen
Affiliations: | University of Cambridge, Cambridge, England, United Kingdom |
Area:
Structural biology, biophysics, biochemistry, fragment-based drug discoveryGoogle:
"Marko Hyvonen"Children
Sign in to add traineeAdrian Harrington | grad student | 2002-2006 | Cambridge |
Ye Gu | grad student | 2008-2012 | Cambridge |
Emily Blythe | grad student | 2012-2013 | Cambridge |
Jane Cat Donaldson | grad student | 2009-2014 | Cambridge |
Miglė Kišonaitė | grad student | 2014-2015 | Cambridge |
Xuelu Wang | grad student | 2012-2016 | Cambridge |
Ruoqi-Emma Xu | grad student | 2012-2016 | Cambridge |
Clare Henry | grad student | 2013-2017 | Cambridge |
Margherite Guiata | grad student | 2016-2017 | Cambridge |
Thomas Cotton | grad student | 2015-2019 | Cambridge |
Joseph McLoughlin | grad student | 2015-2019 | Cambridge |
Richard Zhou | grad student | 2019-2020 | Cambridge |
Teodors Pantelejevs | grad student | 2015-2021 | Cambridge |
Matthew Ratcliff | grad student | 2016-2021 | Cambridge |
Collaborators
Sign in to add collaboratorFlorian Hollfelder | collaborator | 2005- | Cambridge (Chemistry Tree) |
David Spring | collaborator | 2010- | Cambridge (Chemistry Tree) |
Andrea Balan | collaborator | 2016- | University of São Paulo - Institute of Biomedical Science |
Morten Grotli | collaborator | 2018- | University of Gothenburg, Sweden |
Christopher Abell | collaborator | 2004-2020 | University of Cambridge (UK) (Chemistry Tree) |
BETA: Related publications
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Publications
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Brear P, De Fusco C, Atkinson EL, et al. (2022) A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action. Rsc Medicinal Chemistry. 13: 1420-1426 |
Battisti UM, Gao C, Nilsson O, et al. (2022) Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase. Chembiochem : a European Journal of Chemical Biology |
Brear P, Hyvönen M. (2022) Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2α. Acta Crystallographica. Section F, Structural Biology Communications. 78: 348-353 |
Neun S, Brear P, Campbell E, et al. (2022) Functional metagenomic screening identifies an unexpected β-glucuronidase. Nature Chemical Biology |
Karusheva Y, Ratcliff M, Mörseburg A, et al. (2022) The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels. The Journal of Applied Laboratory Medicine |
Pantelejevs T, Hyvönen M. (2022) Divergent binding mode for a protozoan BRC repeat to RAD51. The Biochemical Journal. 479: 1031-1043 |
Atkinson EL, Iegre J, D'Amore C, et al. (2022) Development of small cyclic peptides targeting the CK2α/β interface. Chemical Communications (Cambridge, England). 58: 4791-4794 |
Nain-Perez A, Foller Füchtbauer A, Håversen L, et al. (2022) Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase. European Journal of Medicinal Chemistry. 234: 114270 |
Synakewicz M, Eapen RS, Perez-Riba A, et al. (2022) Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix. Acs Nano. 16: 3895-3905 |
Talbot-Cooper C, Pantelejevs T, Shannon JP, et al. (2022) Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling. Cell Host & Microbe |