Marko Hyvonen

University of Cambridge, Cambridge, England, United Kingdom 
Structural biology, biophysics, biochemistry, fragment-based drug discovery
"Marko Hyvonen"


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Adrian Harrington grad student 2002-2006 Cambridge
Ye Gu grad student 2008-2012 Cambridge
Emily Blythe grad student 2012-2013 Cambridge
Jane Cat Donaldson grad student 2009-2014 Cambridge
Miglė Kišonaitė grad student 2014-2015 Cambridge
Xuelu Wang grad student 2012-2016 Cambridge
Ruoqi-Emma Xu grad student 2012-2016 Cambridge
Clare Henry grad student 2013-2017 Cambridge
Margherite Guiata grad student 2016-2017 Cambridge
Thomas Cotton grad student 2015-2019 Cambridge
Joseph McLoughlin grad student 2015-2019 Cambridge
Richard Zhou grad student 2019-2020 Cambridge
Teodors Pantelejevs grad student 2015-2021 Cambridge
Matthew Ratcliff grad student 2016-2021 Cambridge


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Florian Hollfelder collaborator 2005- Cambridge (Chemistry Tree)
David Spring collaborator 2010- Cambridge (Chemistry Tree)
Andrea Balan collaborator 2016- University of São Paulo - Institute of Biomedical Science
Morten Grotli collaborator 2018- University of Gothenburg, Sweden
Christopher Abell collaborator 2004-2020 University of Cambridge (UK) (Chemistry Tree)
BETA: Related publications


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Brear P, De Fusco C, Atkinson EL, et al. (2022) A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action. Rsc Medicinal Chemistry. 13: 1420-1426
Battisti UM, Gao C, Nilsson O, et al. (2022) Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase. Chembiochem : a European Journal of Chemical Biology
Brear P, Hyvönen M. (2022) Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2α. Acta Crystallographica. Section F, Structural Biology Communications. 78: 348-353
Neun S, Brear P, Campbell E, et al. (2022) Functional metagenomic screening identifies an unexpected β-glucuronidase. Nature Chemical Biology
Karusheva Y, Ratcliff M, Mörseburg A, et al. (2022) The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels. The Journal of Applied Laboratory Medicine
Pantelejevs T, Hyvönen M. (2022) Divergent binding mode for a protozoan BRC repeat to RAD51. The Biochemical Journal. 479: 1031-1043
Atkinson EL, Iegre J, D'Amore C, et al. (2022) Development of small cyclic peptides targeting the CK2α/β interface. Chemical Communications (Cambridge, England). 58: 4791-4794
Nain-Perez A, Foller Füchtbauer A, Håversen L, et al. (2022) Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase. European Journal of Medicinal Chemistry. 234: 114270
Synakewicz M, Eapen RS, Perez-Riba A, et al. (2022) Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix. Acs Nano. 16: 3895-3905
Talbot-Cooper C, Pantelejevs T, Shannon JP, et al. (2022) Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling. Cell Host & Microbe
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